#METABOLOMICS WORKBENCH kuppal2_20190508_113047 DATATRACK_ID:1723 STUDY_ID:ST001181 ANALYSIS_ID:AN001959 PROJECT_ID:PR000793 VERSION 1 CREATED_ON May 15, 2019, 7:59 am #PROJECT PR:PROJECT_TITLE Child Health and Development Studies womb to breast cancer F0 metabolomics PR:PROJECT_SUMMARY This study measured untargeted metabolomics in 397 maternal perinatal serum PR:PROJECT_SUMMARY samples (mostly early postpartum) collected during 1959-1967 in the Child Health PR:PROJECT_SUMMARY and Development Studies (CHDS) and assessed associations between metabolites and PR:PROJECT_SUMMARY environmental chemical concentrations in maternal serum. PR:INSTITUTE Emory University PR:DEPARTMENT Medicine PR:LABORATORY Dean Jones PR:LAST_NAME Hu PR:FIRST_NAME Xin PR:ADDRESS 615 Michael Street, Room 225 PR:EMAIL xin.hu2@emory.edu PR:PHONE 4047275091 PR:CONTRIBUTORS Child Health and Development Studies, Public Health Institute #STUDY ST:STUDY_TITLE Child Health and Development Studies womb to breast cancer F0 metabolomics ST:STUDY_SUMMARY We used high resolution metabolomics to understand DDT-induced alterations of in ST:STUDY_SUMMARY utero environment and potential health effects. This study measured endogenous ST:STUDY_SUMMARY metabolites in 397 maternal perinatal serum samples collected during 1959-1967 ST:STUDY_SUMMARY in the Child Health and Development Studies (CHDS) and assessed associations ST:STUDY_SUMMARY between metabolites and envrionmental chemical concentrations in maternal serum. ST:INSTITUTE Emory University ST:LAST_NAME Hu ST:FIRST_NAME Xin ST:ADDRESS Emory University Whitehead building (Rm 225), 615 Michael Street ST:EMAIL xin.hu2@emory.edu ST:PHONE 4047275091 #SUBJECT SU:SUBJECT_TYPE Human SU:SUBJECT_SPECIES Homo sapiens SU:TAXONOMY_ID 9606 SU:AGE_OR_AGE_RANGE 16-44 years old SU:GENDER Female #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS - 1.01_subj Trimester:4 Mother Age=29; yrdraw=1965; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 1.02_subj Trimester:4 Mother Age=25; yrdraw=1965; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 1.03_subj Trimester:4 Mother Age=29; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 1.04_subj Trimester:4 Mother Age=35; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 1.05_subj Trimester:4 Mother Age=25; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 1.06_subj Trimester:4 Mother Age=33; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 1.07_subj Trimester:4 Mother Age=37; yrdraw=1965; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 1.09_subj Trimester:4 Mother Age=34; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 1.1_subj Trimester:4 Mother Age=27; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 1.11_subj Trimester:4 Mother Age=16; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 1.12_subj Trimester:4 Mother Age=36; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 10.01_subj Trimester:4 Mother Age=38; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 10.03_subj Trimester:4 Mother Age=22; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 10.07_subj Trimester:4 Mother Age=20; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 10.08_subj Trimester:4 Mother Age=30; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 10.09_subj Trimester:4 Mother Age=29; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 10.1_subj Trimester:4 Mother Age=23; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 10.11_subj Trimester:4 Mother Age=29; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 11.01_subj Trimester:4 Mother Age=20; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 11.02_subj Trimester:4 Mother Age=22; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 11.03_subj Trimester:4 Mother Age=23; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 11.04_subj Trimester:4 Mother Age=26; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 11.05_subj Trimester:4 Mother Age=41; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 11.06_subj Trimester:4 Mother Age=35; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 11.09_subj Trimester:4 Mother Age=19; yrdraw=1965; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 11.1_subj Trimester:4 Mother Age=36; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 11.11_subj Trimester:4 Mother Age=21; yrdraw=1964; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 11.12_subj Trimester:4 Mother Age=24; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 12.01_subj Trimester:4 Mother Age=23; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 12.03_subj Trimester:4 Mother Age=28; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 12.05_subj Trimester:4 Mother Age=28; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 12.06_subj Trimester:4 Mother Age=31; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 12.07_subj Trimester:4 Mother Age=23; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 12.08_subj Trimester:4 Mother Age=26; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 12.09_subj Trimester:4 Mother Age=25; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 12.1_subj Trimester:4 Mother Age=33; yrdraw=1960; daysafterdelivery.x=3 SUBJECT_SAMPLE_FACTORS - 12.11_subj Trimester:4 Mother Age=20; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 12.12_subj Trimester:4 Mother Age=22; yrdraw=1960; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 13.01_subj Trimester:3 Mother Age=25; yrdraw=1964; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 13.02_subj Trimester:4 Mother Age=35; yrdraw=1960; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 13.03_subj Trimester:4 Mother Age=24; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 13.04_subj Trimester:4 Mother Age=27; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 13.05_subj Trimester:4 Mother Age=21; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 13.08_subj Trimester:3 Mother Age=31; yrdraw=1964; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 13.09_subj Trimester:4 Mother Age=26; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 13.1_subj Trimester:4 Mother Age=18; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 13.11_subj Trimester:3 Mother Age=24; yrdraw=1964; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 13.12_subj Trimester:4 Mother Age=30; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 14.01_subj Trimester:3 Mother Age=23; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 14.02_subj Trimester:3 Mother Age=23; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 14.03_subj Trimester:3 Mother Age=30; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 14.04_subj Trimester:3 Mother Age=35; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 14.05_subj Trimester:4 Mother Age=36; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 14.06_subj Trimester:4 Mother Age=25; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 14.07_subj Trimester:4 Mother Age=27; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 14.08_subj Trimester:4 Mother Age=20; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 14.09_subj Trimester:4 Mother Age=22; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 14.1_subj Trimester:4 Mother Age=24; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 14.11_subj Trimester:4 Mother Age=36; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 14.12_subj Trimester:4 Mother Age=26; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 15.01_subj Trimester:4 Mother Age=24; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 15.03_subj Trimester:4 Mother Age=22; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 15.04_subj Trimester:4 Mother Age=38; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 15.05_subj Trimester:4 Mother Age=17; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 15.07_subj Trimester:4 Mother Age=20; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 15.08_subj Trimester:4 Mother Age=27; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 15.09_subj Trimester:4 Mother Age=25; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 15.1_subj Trimester:4 Mother Age=20; yrdraw=1963; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 15.11_subj Trimester:4 Mother Age=19; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 15.12_subj Trimester:4 Mother Age=24; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 16.01_subj Trimester:3 Mother Age=23; yrdraw=1961; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 16.02_subj Trimester:4 Mother Age=23; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 16.03_subj Trimester:4 Mother Age=25; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 16.05_subj Trimester:4 Mother Age=36; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 16.06_subj Trimester:4 Mother Age=19; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 16.07_subj Trimester:3 Mother Age=27; yrdraw=1961; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 16.09_subj Trimester:3 Mother Age=17; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 16.1_subj Trimester:4 Mother Age=25; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 16.11_subj Trimester:4 Mother Age=17; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 16.12_subj Trimester:4 Mother Age=36; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 17.02_subj Trimester:4 Mother Age=26; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 17.04_subj Trimester:3 Mother Age=25; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 17.05_subj Trimester:4 Mother Age=34; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 17.06_subj Trimester:4 Mother Age=25; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 17.07_subj Trimester:3 Mother Age=NA; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 17.08_subj Trimester:4 Mother Age=27; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 17.09_subj Trimester:4 Mother Age=21; yrdraw=1962; daysafterdelivery.x=3 SUBJECT_SAMPLE_FACTORS - 17.12_subj Trimester:4 Mother Age=36; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 18.01_subj Trimester:4 Mother Age=31; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 18.03_subj Trimester:4 Mother Age=30; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 18.04_subj Trimester:3 Mother Age=27; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 18.05_subj Trimester:3 Mother Age=32; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 18.06_subj Trimester:4 Mother Age=28; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 18.07_subj Trimester:4 Mother Age=25; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 18.08_subj Trimester:3 Mother Age=39; yrdraw=1959; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 18.09_subj Trimester:4 Mother Age=19; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 18.1_subj Trimester:4 Mother Age=24; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 18.11_subj Trimester:3 Mother Age=31; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 18.12_subj Trimester:4 Mother Age=24; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 19.01_subj Trimester:4 Mother Age=27; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 19.02_subj Trimester:4 Mother Age=19; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 19.03_subj Trimester:4 Mother Age=30; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 19.04_subj Trimester:4 Mother Age=22; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 19.05_subj Trimester:4 Mother Age=36; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 19.06_subj Trimester:4 Mother Age=31; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 19.07_subj Trimester:3 Mother Age=44; yrdraw=1964; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 19.08_subj Trimester:3 Mother Age=39; yrdraw=1964; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 19.09_subj Trimester:3 Mother Age=20; yrdraw=1964; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 19.1_subj Trimester:4 Mother Age=27; yrdraw=1961; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 19.11_subj Trimester:3 Mother Age=19; yrdraw=1964; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 2.01_subj Trimester:4 Mother Age=32; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 2.03_subj Trimester:4 Mother Age=21; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 2.04_subj Trimester:4 Mother Age=36; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 2.05_subj Trimester:4 Mother Age=23; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 2.06_subj Trimester:3 Mother Age=26; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 2.09_subj Trimester:4 Mother Age=25; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 2.11_subj Trimester:4 Mother Age=27; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 2.12_subj Trimester:3 Mother Age=25; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 20.01_subj Trimester:4 Mother Age=29; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 20.03_subj Trimester:4 Mother Age=25; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 20.04_subj Trimester:4 Mother Age=21; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 20.05_subj Trimester:4 Mother Age=27; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 20.06_subj Trimester:4 Mother Age=25; yrdraw=1966; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 20.07_subj Trimester:4 Mother Age=36; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 20.08_subj Trimester:3 Mother Age=33; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 20.09_subj Trimester:3 Mother Age=38; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 20.1_subj Trimester:3 Mother Age=21; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 20.11_subj Trimester:3 Mother Age=35; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 21.01_subj Trimester:3 Mother Age=23; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 21.02_subj Trimester:3 Mother Age=37; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 21.03_subj Trimester:3 Mother Age=30; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 21.04_subj Trimester:4 Mother Age=25; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 21.06_subj Trimester:4 Mother Age=23; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 21.07_subj Trimester:4 Mother Age=20; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 21.08_subj Trimester:4 Mother Age=26; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 21.09_subj Trimester:4 Mother Age=32; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 21.1_subj Trimester:3 Mother Age=25; yrdraw=1959; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 21.11_subj Trimester:4 Mother Age=24; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 21.12_subj Trimester:4 Mother Age=18; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 22.03_subj Trimester:4 Mother Age=24; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 22.06_subj Trimester:4 Mother Age=31; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 22.07_subj Trimester:4 Mother Age=25; yrdraw=1962; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 22.11_subj Trimester:4 Mother Age=35; yrdraw=1962; daysafterdelivery.x=5 SUBJECT_SAMPLE_FACTORS - 22.12_subj Trimester:4 Mother Age=35; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 23.01_subj Trimester:4 Mother Age=24; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 23.02_subj Trimester:3 Mother Age=42; yrdraw=1961; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 23.04_subj Trimester:4 Mother Age=30; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 23.05_subj Trimester:3 Mother Age=31; yrdraw=1961; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 23.06_subj Trimester:3 Mother Age=29; yrdraw=1961; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 23.07_subj Trimester:4 Mother Age=27; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 23.08_subj Trimester:4 Mother Age=24; yrdraw=1961; daysafterdelivery.x=3 SUBJECT_SAMPLE_FACTORS - 23.1_subj Trimester:3 Mother Age=22; yrdraw=1961; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 23.11_subj Trimester:4 Mother Age=28; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 23.12_subj Trimester:4 Mother Age=29; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 24.01_subj Trimester:4 Mother Age=18; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 24.02_subj Trimester:4 Mother Age=27; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 24.03_subj Trimester:3 Mother Age=26; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 24.04_subj Trimester:3 Mother Age=29; yrdraw=1959; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 24.05_subj Trimester:4 Mother Age=33; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 24.06_subj Trimester:2 Mother Age=34; yrdraw=1963; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 24.07_subj Trimester:3 Mother Age=24; yrdraw=1959; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 24.08_subj Trimester:4 Mother Age=21; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 24.09_subj Trimester:2 Mother Age=23; yrdraw=1963; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 24.11_subj Trimester:2 Mother Age=33; yrdraw=1962; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 24.12_subj Trimester:2 Mother Age=25; yrdraw=1963; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 25.01_subj Trimester:3 Mother Age=27; yrdraw=1966; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 25.02_subj Trimester:4 Mother Age=20; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 25.03_subj Trimester:3 Mother Age=21; yrdraw=1965; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 25.04_subj Trimester:4 Mother Age=24; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 25.05_subj Trimester:4 Mother Age=35; yrdraw=1963; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 25.07_subj Trimester:4 Mother Age=28; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 25.08_subj Trimester:4 Mother Age=17; yrdraw=1966; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 25.09_subj Trimester:3 Mother Age=30; yrdraw=1966; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 25.11_subj Trimester:4 Mother Age=20; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 26.01_subj Trimester:4 Mother Age=35; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 26.02_subj Trimester:4 Mother Age=27; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 26.03_subj Trimester:4 Mother Age=38; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 26.04_subj Trimester:4 Mother Age=22; yrdraw=1961; daysafterdelivery.x=- SUBJECT_SAMPLE_FACTORS - 26.05_subj Trimester:4 Mother Age=25; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 26.06_subj Trimester:4 Mother Age=NA; yrdraw=1961; daysafterdelivery.x=3 SUBJECT_SAMPLE_FACTORS - 26.08_subj Trimester:4 Mother Age=34; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 26.09_subj Trimester:4 Mother Age=25; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 26.1_subj Trimester:4 Mother Age=21; yrdraw=1961; daysafterdelivery.x=4 SUBJECT_SAMPLE_FACTORS - 26.11_subj Trimester:4 Mother Age=20; yrdraw=1962; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 27.01_subj Trimester:4 Mother Age=18; yrdraw=1965; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 27.02_subj Trimester:4 Mother Age=24; yrdraw=1964; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 27.03_subj Trimester:4 Mother Age=32; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 27.04_subj Trimester:4 Mother Age=27; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 27.05_subj Trimester:4 Mother Age=17; yrdraw=1965; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 27.06_subj Trimester:4 Mother Age=26; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 27.08_subj Trimester:4 Mother Age=23; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 27.09_subj Trimester:4 Mother Age=19; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 27.11_subj Trimester:4 Mother Age=31; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 28.01_subj Trimester:3 Mother Age=20; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 28.02_subj Trimester:3 Mother Age=20; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 28.03_subj Trimester:4 Mother Age=33; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 28.04_subj Trimester:3 Mother Age=37; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 28.05_subj Trimester:4 Mother Age=21; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 28.06_subj Trimester:4 Mother Age=25; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 28.08_subj Trimester:4 Mother Age=23; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 28.09_subj Trimester:4 Mother Age=28; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 28.1_subj Trimester:3 Mother Age=42; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 28.11_subj Trimester:4 Mother Age=29; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 28.12_subj Trimester:4 Mother Age=26; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 29.01_subj Trimester:4 Mother Age=19; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 29.02_subj Trimester:4 Mother Age=22; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 29.03_subj Trimester:4 Mother Age=21; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 29.04_subj Trimester:3 Mother Age=36; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 29.05_subj Trimester:4 Mother Age=18; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 29.06_subj Trimester:4 Mother Age=23; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 29.08_subj Trimester:3 Mother Age=27; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 29.1_subj Trimester:3 Mother Age=33; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 29.11_subj Trimester:4 Mother Age=16; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 29.12_subj Trimester:4 Mother Age=38; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 3.01_subj Trimester:4 Mother Age=23; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 3.03_subj Trimester:4 Mother Age=34; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 3.05_subj Trimester:4 Mother Age=26; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 3.07_subj Trimester:4 Mother Age=21; yrdraw=1965; daysafterdelivery.x=3 SUBJECT_SAMPLE_FACTORS - 3.08_subj Trimester:4 Mother Age=19; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 3.09_subj Trimester:4 Mother Age=37; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 3.11_subj Trimester:4 Mother Age=18; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 3.12_subj Trimester:4 Mother Age=27; yrdraw=1965; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 30.01_subj Trimester:4 Mother Age=21; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 30.03_subj Trimester:4 Mother Age=21; yrdraw=1964; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 30.04_subj Trimester:4 Mother Age=25; yrdraw=1962; daysafterdelivery.x=3 SUBJECT_SAMPLE_FACTORS - 30.07_subj Trimester:4 Mother Age=28; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 30.08_subj Trimester:4 Mother Age=30; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 30.1_subj Trimester:4 Mother Age=23; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 30.11_subj Trimester:4 Mother Age=22; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 31.01_subj Trimester:4 Mother Age=31; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 31.02_subj Trimester:4 Mother Age=23; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 31.03_subj Trimester:4 Mother Age=26; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 31.04_subj Trimester:4 Mother Age=22; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 31.05_subj Trimester:4 Mother Age=17; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 31.06_subj Trimester:4 Mother Age=31; yrdraw=1966; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 31.07_subj Trimester:4 Mother Age=29; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 31.09_subj Trimester:4 Mother Age=26; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 31.1_subj Trimester:4 Mother Age=25; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 31.12_subj Trimester:4 Mother Age=22; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 32.02_subj Trimester:4 Mother Age=21; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 32.03_subj Trimester:4 Mother Age=21; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 32.04_subj Trimester:4 Mother Age=22; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 32.05_subj Trimester:4 Mother Age=23; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 32.06_subj Trimester:4 Mother Age=34; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 32.07_subj Trimester:1 Mother Age=25; yrdraw=1963; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 32.08_subj Trimester:1 Mother Age=20; yrdraw=1963; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 32.09_subj Trimester:4 Mother Age=22; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 32.1_subj Trimester:4 Mother Age=26; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 32.11_subj Trimester:1 Mother Age=40; yrdraw=1963; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 32.12_subj Trimester:4 Mother Age=18; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 33.01_subj Trimester:3 Mother Age=20; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 33.02_subj Trimester:4 Mother Age=21; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 33.04_subj Trimester:3 Mother Age=26; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 33.05_subj Trimester:3 Mother Age=27; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 33.06_subj Trimester:4 Mother Age=22; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 33.08_subj Trimester:4 Mother Age=39; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 33.1_subj Trimester:4 Mother Age=37; yrdraw=1962; daysafterdelivery.x=3 SUBJECT_SAMPLE_FACTORS - 33.11_subj Trimester:4 Mother Age=30; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 33.12_subj Trimester:4 Mother Age=21; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 34.01_subj Trimester:4 Mother Age=38; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 34.03_subj Trimester:4 Mother Age=28; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 34.06_subj Trimester:4 Mother Age=27; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 35.01_subj Trimester:4 Mother Age=34; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 35.02_subj Trimester:4 Mother Age=22; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 35.03_subj Trimester:4 Mother Age=22; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 35.04_subj Trimester:4 Mother Age=23; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 35.05_subj Trimester:3 Mother Age=22; yrdraw=1962; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 35.06_subj Trimester:4 Mother Age=24; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 35.07_subj Trimester:3 Mother Age=23; yrdraw=1963; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 35.08_subj Trimester:4 Mother Age=31; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 35.1_subj Trimester:4 Mother Age=24; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 35.11_subj Trimester:3 Mother Age=23; yrdraw=1963; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 36.01_subj Trimester:4 Mother Age=22; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 36.02_subj Trimester:4 Mother Age=23; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 36.03_subj Trimester:4 Mother Age=27; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 36.04_subj Trimester:4 Mother Age=26; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 36.05_subj Trimester:4 Mother Age=25; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 36.06_subj Trimester:4 Mother Age=24; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 36.07_subj Trimester:4 Mother Age=27; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 36.08_subj Trimester:4 Mother Age=34; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 36.09_subj Trimester:4 Mother Age=27; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 36.11_subj Trimester:4 Mother Age=25; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 37.01_subj Trimester:3 Mother Age=31; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 37.03_subj Trimester:4 Mother Age=21; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 37.04_subj Trimester:4 Mother Age=24; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 37.05_subj Trimester:3 Mother Age=30; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 37.06_subj Trimester:4 Mother Age=24; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 37.07_subj Trimester:3 Mother Age=23; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 37.08_subj Trimester:4 Mother Age=39; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 37.1_subj Trimester:4 Mother Age=34; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 37.11_subj Trimester:4 Mother Age=26; yrdraw=1963; daysafterdelivery.x=3 SUBJECT_SAMPLE_FACTORS - 38.01_subj Trimester:4 Mother Age=35; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 38.02_subj Trimester:4 Mother Age=24; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 38.03_subj Trimester:2 Mother Age=26; yrdraw=1962; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 38.04_subj Trimester:2 Mother Age=26; yrdraw=1961; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 38.05_subj Trimester:2 Mother Age=26; yrdraw=1962; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 38.06_subj Trimester:4 Mother Age=30; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 38.07_subj Trimester:4 Mother Age=32; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 38.08_subj Trimester:4 Mother Age=29; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 38.09_subj Trimester:4 Mother Age=23; yrdraw=1962; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 38.1_subj Trimester:4 Mother Age=20; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 38.11_subj Trimester:4 Mother Age=19; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 39.01_subj Trimester:2 Mother Age=30; yrdraw=1963; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 39.02_subj Trimester:2 Mother Age=21; yrdraw=1963; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 39.03_subj Trimester:3 Mother Age=27; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 39.04_subj Trimester:4 Mother Age=18; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 39.05_subj Trimester:3 Mother Age=26; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 39.06_subj Trimester:2 Mother Age=22; yrdraw=1964; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 39.07_subj Trimester:4 Mother Age=28; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 39.09_subj Trimester:4 Mother Age=26; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 39.1_subj Trimester:2 Mother Age=22; yrdraw=1963; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 39.11_subj Trimester:4 Mother Age=27; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 39.12_subj Trimester:3 Mother Age=26; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 4.02_subj Trimester:4 Mother Age=18; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 4.03_subj Trimester:4 Mother Age=42; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 4.04_subj Trimester:4 Mother Age=19; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 4.07_subj Trimester:4 Mother Age=37; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 4.09_subj Trimester:4 Mother Age=23; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 4.1_subj Trimester:4 Mother Age=42; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 4.11_subj Trimester:4 Mother Age=18; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 4.12_subj Trimester:4 Mother Age=19; yrdraw=1963; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 40.01_subj Trimester:4 Mother Age=22; yrdraw=1960; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 40.04_subj Trimester:4 Mother Age=25; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 40.07_subj Trimester:4 Mother Age=36; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 40.08_subj Trimester:4 Mother Age=27; yrdraw=1961; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 40.09_subj Trimester:3 Mother Age=22; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 40.1_subj Trimester:3 Mother Age=20; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 40.11_subj Trimester:4 Mother Age=27; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 40.12_subj Trimester:4 Mother Age=28; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 41.01_subj Trimester:3 Mother Age=30; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 41.02_subj Trimester:3 Mother Age=24; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 41.03_subj Trimester:4 Mother Age=22; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 41.04_subj Trimester:4 Mother Age=19; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 41.05_subj Trimester:2 Mother Age=24; yrdraw=1962; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 41.06_subj Trimester:4 Mother Age=16; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 41.07_subj Trimester:2 Mother Age=34; yrdraw=1961; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 41.08_subj Trimester:2 Mother Age=28; yrdraw=1962; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 41.09_subj Trimester:3 Mother Age=23; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 41.1_subj Trimester:2 Mother Age=22; yrdraw=1961; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 41.11_subj Trimester:4 Mother Age=28; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 41.12_subj Trimester:3 Mother Age=42; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 42.01_subj Trimester:4 Mother Age=24; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 42.04_subj Trimester:4 Mother Age=22; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 42.05_subj Trimester:4 Mother Age=24; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 42.06_subj Trimester:4 Mother Age=35; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 42.07_subj Trimester:4 Mother Age=18; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 42.08_subj Trimester:4 Mother Age=32; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 5.01_subj Trimester:4 Mother Age=22; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 5.02_subj Trimester:4 Mother Age=23; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 5.03_subj Trimester:3 Mother Age=40; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 5.04_subj Trimester:3 Mother Age=26; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 5.06_subj Trimester:4 Mother Age=26; yrdraw=1966; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 5.07_subj Trimester:4 Mother Age=32; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 5.08_subj Trimester:4 Mother Age=38; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 5.1_subj Trimester:3 Mother Age=19; yrdraw=1960; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 5.11_subj Trimester:4 Mother Age=36; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 5.12_subj Trimester:4 Mother Age=22; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 6.01_subj Trimester:4 Mother Age=31; yrdraw=1961; daysafterdelivery.x=3 SUBJECT_SAMPLE_FACTORS - 6.02_subj Trimester:4 Mother Age=26; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 6.03_subj Trimester:4 Mother Age=39; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 6.04_subj Trimester:4 Mother Age=27; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 6.05_subj Trimester:4 Mother Age=22; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 6.06_subj Trimester:4 Mother Age=36; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 6.07_subj Trimester:4 Mother Age=38; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 6.08_subj Trimester:4 Mother Age=28; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 6.09_subj Trimester:4 Mother Age=41; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 6.1_subj Trimester:4 Mother Age=32; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 6.11_subj Trimester:4 Mother Age=25; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 6.12_subj Trimester:4 Mother Age=29; yrdraw=1961; daysafterdelivery.x=3 SUBJECT_SAMPLE_FACTORS - 7.01_subj Trimester:4 Mother Age=18; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 7.02_subj Trimester:4 Mother Age=24; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 7.03_subj Trimester:4 Mother Age=24; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 7.04_subj Trimester:4 Mother Age=27; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 7.05_subj Trimester:4 Mother Age=29; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 7.06_subj Trimester:4 Mother Age=21; yrdraw=1966; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 7.07_subj Trimester:4 Mother Age=40; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 7.08_subj Trimester:4 Mother Age=32; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 7.09_subj Trimester:4 Mother Age=25; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 7.1_subj Trimester:4 Mother Age=18; yrdraw=1962; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 7.11_subj Trimester:4 Mother Age=23; yrdraw=1966; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 8.01_subj Trimester:4 Mother Age=41; yrdraw=1965; daysafterdelivery.x=5 SUBJECT_SAMPLE_FACTORS - 8.02_subj Trimester:4 Mother Age=26; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 8.03_subj Trimester:4 Mother Age=31; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 8.05_subj Trimester:4 Mother Age=18; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 8.06_subj Trimester:4 Mother Age=27; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 8.07_subj Trimester:4 Mother Age=21; yrdraw=1965; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 8.08_subj Trimester:4 Mother Age=23; yrdraw=1964; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 8.09_subj Trimester:4 Mother Age=24; yrdraw=1965; daysafterdelivery.x=1 SUBJECT_SAMPLE_FACTORS - 8.1_subj Trimester:4 Mother Age=28; yrdraw=1961; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 8.11_subj Trimester:4 Mother Age=22; yrdraw=1965; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 9.01_subj Trimester:3 Mother Age=41; yrdraw=1961; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 9.02_subj Trimester:3 Mother Age=22; yrdraw=1961; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 9.04_subj Trimester:4 Mother Age=38; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 9.05_subj Trimester:4 Mother Age=32; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 9.07_subj Trimester:4 Mother Age=20; yrdraw=1960; daysafterdelivery.x=2 SUBJECT_SAMPLE_FACTORS - 9.08_subj Trimester:3 Mother Age=25; yrdraw=1961; daysafterdelivery.x=N SUBJECT_SAMPLE_FACTORS - 9.1_subj Trimester:4 Mother Age=24; yrdraw=1960; daysafterdelivery.x=2 #COLLECTION CO:COLLECTION_SUMMARY Blood serum samples were collected from nonfasting participants in the CHDS CO:COLLECTION_SUMMARY Study during preganancy (trimester 1-3) or early postpartum (trimester 4). The CO:COLLECTION_SUMMARY CHDS recruited women residing in the Oakland, California area who were members CO:COLLECTION_SUMMARY of the Kaiser Foundation Health Plan and received obstetric care for pregnancies CO:COLLECTION_SUMMARY between 1959 and 1967. All serum samples were stored at -20°C at the repository CO:COLLECTION_SUMMARY and shipped frozen to the laboratory for further storage at -80°C. CO:SAMPLE_TYPE Blood (serum) #TREATMENT TR:TREATMENT_SUMMARY Samples were received frozen in aliquouts of <250uL. Prior to analysis, samples TR:TREATMENT_SUMMARY were thawed and prepared for HRM analysis using the standard protocols described TR:TREATMENT_SUMMARY in the Sample Preparation section. #SAMPLEPREP SP:SAMPLEPREP_SUMMARY Samples were prepared for metabolomics analysis using established SP:SAMPLEPREP_SUMMARY methods(Johnson et al. (2010). Analyst; Go et al. (2015). Tox Sci). Prior to SP:SAMPLEPREP_SUMMARY analysis, plasma aliquots were removed from storage at -80 degrees C and thawed SP:SAMPLEPREP_SUMMARY on ice. Each cryotube was then vortexed briefly to ensure homogeneity, and 50 SP:SAMPLEPREP_SUMMARY microliters was transferred to a clean microfuge tube. Immediately after, the SP:SAMPLEPREP_SUMMARY plasma was treated with 100 microliters of ice-cold LC-MS grade acetonitrile SP:SAMPLEPREP_SUMMARY (Sigma Aldrich) containing 2.5 microliters of internal standard solution with SP:SAMPLEPREP_SUMMARY eight stable isotopic chemicals selected to cover a range of chemical SP:SAMPLEPREP_SUMMARY properties. Following addition of acetonitrile, urine was equilibrated for 30 SP:SAMPLEPREP_SUMMARY min on ice, upon which precipitated proteins were removed by centrifuge (14,000 SP:SAMPLEPREP_SUMMARY rpm at 4 degrees C for 10 min). The resulting supernatant (100 microliters) was SP:SAMPLEPREP_SUMMARY removed, added to a low volume autosampler vial and maintained at 4 degrees C SP:SAMPLEPREP_SUMMARY until analysis (<22 h). SP:SAMPLEPREP_PROTOCOL_ID HRM_SP_082016_01 SP:SAMPLEPREP_PROTOCOL_FILENAME HRM_sample_preparation_082016_01.pdf #CHROMATOGRAPHY CH:CHROMATOGRAPHY_SUMMARY Mass spectral data were collected with a 10-minute gradient on a Thermo CH:CHROMATOGRAPHY_SUMMARY QExactive coupled with Dionex Ultimate 3000 (Thermo Fisher, San Diego, CA) set CH:CHROMATOGRAPHY_SUMMARY to collect data from m/z 85 to 1275 in positive ionization mode at 70,000 CH:CHROMATOGRAPHY_SUMMARY resolution. Three technical replicates were run for each sample using dual CH:CHROMATOGRAPHY_SUMMARY chromatography measuring both polarities (positive and negative) with a C18 CH:CHROMATOGRAPHY_SUMMARY column (Higgins Analytical, 100x2.1mm, 5uL). The right pump controls the CH:CHROMATOGRAPHY_SUMMARY gradient with Solvent A as 100% water, Solvent B as 100% Acetontrile, and CH:CHROMATOGRAPHY_SUMMARY Solvent C as 98% water with 2% Formic Acid. The left pump is set up to wash CH:CHROMATOGRAPHY_SUMMARY (Acetonitrile with 2% Formic Acid) one of the columns while the other column is CH:CHROMATOGRAPHY_SUMMARY running the gradient. CH:CHROMATOGRAPHY_TYPE Reversed phase CH:INSTRUMENT_NAME Thermo Dionex Ultimate 3000 CH:COLUMN_NAME Thermo Accucore C18 (100 2.1mm, 2.6um) #ANALYSIS AN:ANALYSIS_TYPE MS AN:LABORATORY_NAME Clinical Biomarker AN:OPERATOR_NAME Vilinh Tran AN:DETECTOR_TYPE Orbitrap AN:SOFTWARE_VERSION Xcalibur 3.0.63 AN:ACQUISITION_DATE March, 2014 #MS MS:INSTRUMENT_NAME Thermo Q Exactive Orbitrap MS:INSTRUMENT_TYPE Orbitrap MS:MS_TYPE ESI MS:ION_MODE POSITIVE MS:MS_COMMENTS Mass spectral data were collected with a 10-minute gradient on a Thermo MS:MS_COMMENTS QExactive coupled with Dionex Ultimate 3000 (Thermo Fisher, San Diego, CA) set MS:MS_COMMENTS to collect data from m/z 85 to 1275 in positive ionization mode at 70,000 MS:MS_COMMENTS resolution. Three technical replicates were run for each sample using dual MS:MS_COMMENTS chromatography measuring both polarities (positive and negative) with a C18 MS:MS_COMMENTS column (Higgins Analytical, 100x2.1mm, 5uL). The right pump controls the MS:MS_COMMENTS gradient with Solvent A as 100% water, Solvent B as 100% Acetontrile, and MS:MS_COMMENTS Solvent C as 98% water with 2% Formic Acid. The left pump is set up to wash MS:MS_COMMENTS (Acetonitrile with 2% Formic Acid) one of the columns while the other column is MS:MS_COMMENTS running the gradient. The raw data was processed with Xcalibur 3.0.63 MS:ACQUISITION_DATE March, 2014 MS:MS_RESULTS_FILE ST001181_AN001959_Results.txt UNITS:Peak area Has m/z:Yes Has RT:Yes RT units:Seconds #END