#METABOLOMICS WORKBENCH efahy_20191217_103517_mwtab.txt DATATRACK_ID:1874 STUDY_ID:ST001289 ANALYSIS_ID:AN002142 PROJECT_ID:PR000871
VERSION             	1
CREATED_ON             	December 17, 2019, 11:05 am
#PROJECT
PR:PROJECT_TITLE                 	Regulated accumulation of desmosterol integrates macrophage lipid metabolism and
PR:PROJECT_TITLE                 	inflammatory responses
PR:PROJECT_SUMMARY               	Inflammation and macrophage foam cells are characteristic features of
PR:PROJECT_SUMMARY               	atherosclerotic lesions, but the mechanisms linking cholesterol accumulation to
PR:PROJECT_SUMMARY               	inflammation and LXR-dependent response pathways are poorly understood. To
PR:PROJECT_SUMMARY               	investigate this relationship, we utilized lipidomic and transcriptomic methods
PR:PROJECT_SUMMARY               	to evaluate the effect of diet and LDL receptor genotype on macrophage foam cell
PR:PROJECT_SUMMARY               	formation within the peritoneal cavities of mice. Foam cell formation was
PR:PROJECT_SUMMARY               	associated with significant changes in hundreds of lipid species and unexpected
PR:PROJECT_SUMMARY               	suppression, rather than activation, of inflammatory gene expression. We provide
PR:PROJECT_SUMMARY               	evidence that regulated accumulation of desmosterol underlies many of the
PR:PROJECT_SUMMARY               	homeostatic responses observed in macrophage foam cells, including activation of
PR:PROJECT_SUMMARY               	LXR target genes, inhibition of SREBP target genes, selective reprogramming of
PR:PROJECT_SUMMARY               	fatty acid metabolism and suppression of inflammatory response genes. These
PR:PROJECT_SUMMARY               	observations suggest that macrophage activation in atherosclerotic lesions
PR:PROJECT_SUMMARY               	results from extrinsic, pro-inflammatory signals generated within the artery
PR:PROJECT_SUMMARY               	wall that suppress homeostatic and anti-inflammatory functions of desmosterol.
PR:INSTITUTE                     	University of California, San Diego
PR:DEPARTMENT                    	Bioengineering
PR:LAST_NAME                     	Fahy
PR:FIRST_NAME                    	Eoin
PR:ADDRESS                       	9500 Gilman, La Jolla, CA, 92093, USA
PR:EMAIL                         	efahy@ucsd.edu
PR:PHONE                         	858-534-4076
#STUDY
ST:STUDY_TITLE                   	Regulated accumulation of desmosterol integrates macrophage lipid metabolism and
ST:STUDY_TITLE                   	inflammatory responses
ST:STUDY_SUMMARY                 	To investigate the relationship between hypercholesterolemia, foam cell
ST:STUDY_SUMMARY                 	formation and inflammation, we performed lipidomic and transcriptomic analyses
ST:STUDY_SUMMARY                 	of elicited peritoneal macrophages in wild type (WT) or LDL receptor knockout
ST:STUDY_SUMMARY                 	(LDLR KO) mice fed either a normal cholesterol, normal fat (NCNF) diet or a high
ST:STUDY_SUMMARY                 	cholesterol, high fat (HCHF) 'Western' style diet. The combination of the LDLR
ST:STUDY_SUMMARY                 	KO genotype and the HCHF diet results in the formation of macrophage foam cells
ST:STUDY_SUMMARY                 	in the elicited peritoneal macrophage population. Analysis of macrophages from
ST:STUDY_SUMMARY                 	the above four experimental groups revealed massive reprogramming of the
ST:STUDY_SUMMARY                 	lipidome in response to both diet and genotype. These studies confirmed and
ST:STUDY_SUMMARY                 	extended prior knowledge regarding the roles of SREBP and LXR signaling in
ST:STUDY_SUMMARY                 	cholesterol and fatty acid homeostasis. Unexpectedly, peritoneal macrophage foam
ST:STUDY_SUMMARY                 	cells exhibited a strongly 'deactivated' phenotype, with marked suppression of
ST:STUDY_SUMMARY                 	pro-inflammatory mediators that are normally characteristic of the inflammatory
ST:STUDY_SUMMARY                 	responses associated with atherosclerotic lesions. Many of these changes in gene
ST:STUDY_SUMMARY                 	expression and lipid metabolism appear to be related to the paradoxical
ST:STUDY_SUMMARY                 	accumulation of high levels of desmosterol, the last intermediate in the Bloch
ST:STUDY_SUMMARY                 	pathway of cholesterol biosynthesis. WT or LDLR KO mice were fed either a NCNF
ST:STUDY_SUMMARY                 	diet or a HCHF diet for twelve weeks to establish four experimental groups
ST:STUDY_SUMMARY                 	(WT-NCNF diet, WT-HCHF diet, KO-NCNF diet, and KO-HCHF diet). As expected, the
ST:STUDY_SUMMARY                 	combination of the HCHF diet and LDLR KO genotype resulted in a synergistic
ST:STUDY_SUMMARY                 	effect on serum lipid levels. Elicited peritoneal macrophages (92-96%
ST:STUDY_SUMMARY                 	F4/80-positive) were immediately prepared for analysis, thereby preserving in
ST:STUDY_SUMMARY                 	vivo gene expression and lipid profiles. Macrophages derived from LDLR KO mice
ST:STUDY_SUMMARY                 	fed the HCHF diet contained nearly four-fold more total cholesterol than cells
ST:STUDY_SUMMARY                 	from WT mice fed the same diet. Quantitative analysis of 245 lipid species
ST:STUDY_SUMMARY                 	revealed significant changes in nearly all major lipid classes. Using a two-way
ST:STUDY_SUMMARY                 	ANOVA model, we found that 176 (72%) of the lipids analyzed were significantly
ST:STUDY_SUMMARY                 	affected by the HCHF diet, 133 (54%) by the LDLR KO genotype, and 114 (46%) by
ST:STUDY_SUMMARY                 	interactions between the HCHF diet and LDLR KO genotype. Many of the observed
ST:STUDY_SUMMARY                 	interactions (60%) were synergistic.
ST:INSTITUTE                     	LIPID MAPS
ST:DEPARTMENT                    	Multiple
ST:LABORATORY                    	Multiple
ST:LAST_NAME                     	Fahy
ST:FIRST_NAME                    	Eoin
ST:ADDRESS                       	9500 Gilman, La Jolla, CA, 92093, USA
ST:EMAIL                         	efahy@ucsd.edu
ST:PHONE                         	858-534-4076
ST:PUBLICATIONS                  	Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D,
ST:PUBLICATIONS                  	Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy
ST:PUBLICATIONS                  	RC, Merrill AH Jr, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E,
ST:PUBLICATIONS                  	Subramaniam S, Quehenberger O, Russell DW, Glass CK. Regulated accumulation of
ST:PUBLICATIONS                  	desmosterol integrates macrophage lipid metabolism and inflammatory responses.
ST:PUBLICATIONS                  	Cell. 2012 Sep 28;151(1):138-52. doi: 10.1016/j.cell.2012.06.054. PMID:
ST:PUBLICATIONS                  	23021221; PMCID: PMC3464914.
#SUBJECT
SU:SUBJECT_TYPE                  	Mammal
SU:SUBJECT_SPECIES               	Mus musculus
SU:TAXONOMY_ID                   	10090
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data
SUBJECT_SAMPLE_FACTORS           	-	5_1	Genotype:Wild type | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	5_2	Genotype:Wild type | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	5_3	Genotype:Wild type | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	5_4	Genotype:Wild type | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	5_5	Genotype:Wild type | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	5_6	Genotype:Wild type | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	5_7	Genotype:Wild type | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	5_8	Genotype:Wild type | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	5_9	Genotype:Wild type | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	6_1	Genotype:Wild type | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	6_2	Genotype:Wild type | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	6_3	Genotype:Wild type | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	6_4	Genotype:Wild type | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	6_5	Genotype:Wild type | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	6_6	Genotype:Wild type | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	6_7	Genotype:Wild type | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	6_8	Genotype:Wild type | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	6_9	Genotype:Wild type | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	7_1	Genotype:LDLR-KO | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	7_2	Genotype:LDLR-KO | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	7_3	Genotype:LDLR-KO | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	7_4	Genotype:LDLR-KO | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	7_5	Genotype:LDLR-KO | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	7_6	Genotype:LDLR-KO | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	7_7	Genotype:LDLR-KO | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	7_8	Genotype:LDLR-KO | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	7_9	Genotype:LDLR-KO | Diet:Normal	
SUBJECT_SAMPLE_FACTORS           	-	8_1	Genotype:LDLR-KO | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	8_2	Genotype:LDLR-KO | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	8_3	Genotype:LDLR-KO | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	8_4	Genotype:LDLR-KO | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	8_5	Genotype:LDLR-KO | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	8_6	Genotype:LDLR-KO | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	8_7	Genotype:LDLR-KO | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	8_8	Genotype:LDLR-KO | Diet:High fat	
SUBJECT_SAMPLE_FACTORS           	-	8_9	Genotype:LDLR-KO | Diet:High fat	
#COLLECTION
CO:COLLECTION_SUMMARY            	Male WT C57BL6 or LDL receptor knockout mice (Jackson Laboratory) were fed a
CO:COLLECTION_SUMMARY            	normal cholesterol/normal fat (NCNF) diet or a high cholesterol/high fat (HCHF)
CO:COLLECTION_SUMMARY            	diet (Harlan Teklad, catalog # 96121 including 21% milk fat and 1.25%
CO:COLLECTION_SUMMARY            	cholesterol) for 12 weeks in an IACUC-approved animal facility. Cells were
CO:COLLECTION_SUMMARY            	harvested from the peritoneal cavity 4 days after i.p. administration of 3%
CO:COLLECTION_SUMMARY            	thioglycollate medium. Cells were immediately counted, aliquoted, pelleted and
CO:COLLECTION_SUMMARY            	sent for cDNA microarray analysis and lipid measurement. For all other
CO:COLLECTION_SUMMARY            	experiments primary cells were isolated from male 6–8 week-old C57BL6 mice
CO:COLLECTION_SUMMARY            	(Charles River Laboratories).
CO:SAMPLE_TYPE                   	Macrophages
#TREATMENT
TR:TREATMENT_SUMMARY             	Mouse thioglycollate-elicited macrophages and bone marrow derived macrophages
TR:TREATMENT_SUMMARY             	were obtained and cultured as described previously (Heinz et al., 2010). For
TR:TREATMENT_SUMMARY             	various ligand treatments, cells were in Phenol-red free RPMI-1640 (Invitrogen)
TR:TREATMENT_SUMMARY             	supplemented with either 10% heat-inactivated FBS (Hyclone) or 10%
TR:TREATMENT_SUMMARY             	lipid-deficient FBS (Hyclone) for 24hr before treatment, then treated with
TR:TREATMENT_SUMMARY             	either 1µM GW3965, 0.25-20µM desmosterol, or 0.3-30µg/ml cholesterol for
TR:TREATMENT_SUMMARY             	12-24hr. 50µM melavonate and 10µM Mevastatin (Sigma) were added to media in
TR:TREATMENT_SUMMARY             	desmosterol response experiments. For TLR repression studies, cells were
TR:TREATMENT_SUMMARY             	cultured in medium containing Phenol-red free RPMI 1640 (Invitrogen) with either
TR:TREATMENT_SUMMARY             	heat-inactivated FBS (Hyclone) or lipid-deficient FBS (Hyclone) for 24hr, then
TR:TREATMENT_SUMMARY             	pretreated with either 20-30µM desmosterol, 50µg/ml cholesterol, 5µM
TR:TREATMENT_SUMMARY             	triparanol, or 50-100µM 9Z-palmitoleic acid for 18hr. Cells were stimulated
TR:TREATMENT_SUMMARY             	with Pam3CSK4 (300ng/ml), PolyI:C (50ng/ml), LPS (100ng/ml), TNFa (30ng/ml), or
TR:TREATMENT_SUMMARY             	KLA (100ng/ml) for 6hr. See Extended Experimental Procedures for additional
TR:TREATMENT_SUMMARY             	details at https://doi.org/10.1016/j.cell.2012.06.054
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	The various extraction procedures and lipidomic analyses for each lipid class
SP:SAMPLEPREP_SUMMARY            	are described in the <a
SP:SAMPLEPREP_SUMMARY            	href=https://doi.org/10.1016/j.cell.2012.06.054>publication</a>
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_SUMMARY        	See publication for details <a
CH:CHROMATOGRAPHY_SUMMARY        	href=https://doi.org/10.1016/j.cell.2012.06.054>publication</a>
CH:CHROMATOGRAPHY_TYPE           	Several
CH:INSTRUMENT_NAME               	Several
CH:COLUMN_NAME                   	Several
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:INSTRUMENT_NAME               	Several
MS:INSTRUMENT_TYPE               	Several
MS:MS_TYPE                       	Other
MS:ION_MODE                      	UNSPECIFIED
MS:MS_COMMENTS                   	See publication for details. <a
MS:MS_COMMENTS                   	href=https://doi.org/10.1016/j.cell.2012.06.054>publication</a>
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS	pmol/1E6 cells
MS_METABOLITE_DATA_START
Samples	5_1	5_2	5_3	5_4	5_5	5_6	5_7	5_8	5_9	6_1	6_2	6_3	6_4	6_5	6_6	6_7	6_8	6_9	7_1	7_2	7_3	7_4	7_5	7_6	7_7	7_8	7_9	8_1	8_2	8_3	8_4	8_5	8_6	8_7	8_8	8_9
Factors	Genotype:Wild type | Diet:Normal	Genotype:Wild type | Diet:Normal	Genotype:Wild type | Diet:Normal	Genotype:Wild type | Diet:Normal	Genotype:Wild type | Diet:Normal	Genotype:Wild type | Diet:Normal	Genotype:Wild type | Diet:Normal	Genotype:Wild type | Diet:Normal	Genotype:Wild type | Diet:Normal	Genotype:Wild type | Diet:High fat	Genotype:Wild type | Diet:High fat	Genotype:Wild type | Diet:High fat	Genotype:Wild type | Diet:High fat	Genotype:Wild type | Diet:High fat	Genotype:Wild type | Diet:High fat	Genotype:Wild type | Diet:High fat	Genotype:Wild type | Diet:High fat	Genotype:Wild type | Diet:High fat	Genotype:LDLR-KO | Diet:Normal	Genotype:LDLR-KO | Diet:Normal	Genotype:LDLR-KO | Diet:Normal	Genotype:LDLR-KO | Diet:Normal	Genotype:LDLR-KO | Diet:Normal	Genotype:LDLR-KO | Diet:Normal	Genotype:LDLR-KO | Diet:Normal	Genotype:LDLR-KO | Diet:Normal	Genotype:LDLR-KO | Diet:Normal	Genotype:LDLR-KO | Diet:High fat	Genotype:LDLR-KO | Diet:High fat	Genotype:LDLR-KO | Diet:High fat	Genotype:LDLR-KO | Diet:High fat	Genotype:LDLR-KO | Diet:High fat	Genotype:LDLR-KO | Diet:High fat	Genotype:LDLR-KO | Diet:High fat	Genotype:LDLR-KO | Diet:High fat	Genotype:LDLR-KO | Diet:High fat
10Z-Heptadecenoic acid	0.8	0.4	0.6	0.8	1.1	0.9	1.1	0.8	0.6	5.3	4.5	2.2	8.9	10.6	9.6	7.2	9	7.3	0.8	1.3	0.9	13.2	0.7	0.9	0.6	0.5	1.1	11.9	11.5	11.5	11.9	16.1	12.9	13	14.9	12.5
11(12)-EpETE	1.3	0.3	0.3	0.2	0.3	0.4	0.3	0.5	0.3										0.2	0.2	0.9	0.6	0.2	0.3	0.7	0.3	0.1	0.2	0.2	0.4	0.1	0.2	0.2	0.2	0.1	0.6
11-HETE	0.8	0.4	0.4	0.3	0.5	0.3	0.4	0.3	0.7	0.2	0.5	0.5	0.6	0.6	0.3	0.5	0.8	0.8	0.4	0.4	0.3	0.6	0.4	0.8	0.3	1.7	0.9	0.3	0.4	0.3	0.4	0.4	0.2	0.3	0.5	0.3
11Z,14Z-Eicosadienoic acid	155.8	148.8	178.3	178	251.9	240.4	209.6	204.4	205	48.8	48.1	50	76.1	84.8	83.3	75.5	72.1	69.2	299.6	310.7	309.2	289.9	280.4	306.4	324.8	337.5	303.8	130	107.9	106.2	112.5	139.7	112.1	90.9	106.4	84.8
12-HETE	49.3	44.4	40.3	101.6	97.5	127.1	120.7	131.4	132.3	11.6	13.8	6.3	63.1	67.6	45	105.9	123.4	121.8	160.7	163.7	162.9	156.5	253.5	272.8	193.4	202.1	83.9	31.9	41.7	50.1	48.5	45.3	44.5	64.9	77.4	74.4
12-Oxo-ETE	4.9	1.6	1.1	1.2	1.1	2.2	1.1	2.2	1.1										1.3	1.2	4.3	1.1	1.2	2.2		2.9	1.2	0.9	1	2.3	1		1.2	1.5		2
13,16,19-Docosatrienoic acid	1.3	1.3	1.4	1.7	2.2	2.2	2.1	1.8	2.1	1.7	1.8	1.7	2	2	2.2	2.4	2.2	3	3.1	2.9	3.1	2.8	3.2	3.2	3.3	3.6	3.3	3	3	3.1	3.9	4.1	3.7	2.6	2.7	2.9
13Z,16Z-Docosadienoic acid	50.8	49.7	62.8	58.6	86.2	80.9	80.1	70.5	70.5	20.1	14.3	15.2	20.2	24.7	21.6	22.8	21.8	25.4	109.8	111.2	118.3	103	110.9	116.6	124.7	134.7	112.6	34.9	34.8	43	31.1	48.3	32.7	22	30.1	20.5
14(15)-EpETE	8.8	1.3	1	1.8	1.5	3.8	2.1	5.2	1.6										1.9	2.4	2.3	1.5	3	2	3.3	1.8	0.6	0.8	0.8	3.2	1.1	0.6	1.1	1.2		4.9
15-Deoxy-delta-12,14-PGD2	1.7	1.1	2.4	1.7	4	4.6	2.7	3.2	1.9	2.8	0.8	1.5	5.4	0.3	0.2	0.9	3.2	0.6	3.2	3.3	0.9	2.6	3.6	3.5	4.4	0.8	0.6	2.4	3.3	4.5	2.8	3.2	3.7	4.2	2.9	4.4
15-Deoxy-delta-12,14-PGJ2	1.1	0.1	0.9	0.4	1.6	2	2	1.9	0.9	0.3	1.4	2	0.6	1.9	0.6	1.5	0.4	0.6	18	29.7	9.9	14.8	11.5	10.8	9.6	35.9	43.9	19.9	23.5	15.7	16.7	15.4	25.9	22.5	24.7	19.3
15S-HETE	8.2	8.2	6.2	10.6	9.4	9.8	10.2	9.7	11.2	25.8	27.3	23.8	14.3	20.2	19.4	26.4	21.1	30.7	10.7	16.8	14	11.4	9.7	24.7	16.3	16.7	14	2.3	2.9	2.4	2.2	1.6	3.6	1.9	-0.3	2.9
2,3-Dinor-TXB2	1	1.7	0.8	2.6	3	-0.2	3.3	3.1	0.7				0.9	2.5	1	5.4	2.4	2.2	6.3	6.9	4.5	0.7	1.8	17.1	7.9	0.5	0.1	2.1	1.2	2.9	2.1	4.3	1.7	0.8	2.3	6.3
20-HETE	23.2	13.9	10.2	11.3	10.8	10.7	15.6	12.5	7.6	15.4	12.2	7.4	6.5	15.8	7.6	16.3	3.1	5.7	9.6	9.5	25.9	9.3	34.7	7.6	24.9	7.9	6	9.6	11.8	14	8.7	16	14.5	23.9	17.1	8.6
22R-Hydroxycholesterol							5.2	7.7			9.4	4.1			16.3			22.1	13.7	4.5	1.9	10.2	4.8	8.2	12.4	3.2	4.9	13.6	16.1		5.2	19.9	35.3	3.7	9	4.4
24,25-Epoxycholesterol	0.249	0.131	0.147	0.127						0.032	0.049	0.039	0.069	0.059					0.267	0.271	0.12	0.17	0.161					0.165	0.229	0.211	0.241	0.239				
24S-Hydroxycholesterol	0.221	0.185	0.336	0.288						0.308	0.457	0.471	0.385	0.333					0.582	1.101	0.612	0.567	0.54					6.286	5.119	3.169	6.909	9.219				
25-Hydroxycholesterol							0.9	0.3	1.5		2.1	1.4			2.2		0.4	1.9	2.8	1.1	1.2	2.2	1.6	2.5	2.8	1.1	0.8	4.9	5.3	2.8	2.7	3.8	4.9	4.1	3.5	2.4
27-Hydroxycholesterol							2.3	0.9			1.4	0.6	0.9	0.7	2.4		1.2	1.9	1.4		5.2	1.4	0.9	1.1	1.4	1.4	0.6	2.3	2.2	1.5	3	3.4	3.9	2.8	3.1	2
4beta-Hydroxy-cholesterol	4	4	4.1	4.8	4.5	4.9	5.5	4.9	5	3	4	3.5	3.3	3.1	5.2	4.9	5.2	5.9	5.3	5.2	5.1	4.9	4.9	5.8	4.9	4.1	5.3	4.6	4.2	3.8	3.7	4	4.3	3.7	3.8	4.5
5,8,11-Eicosatrienoic acid	59.7	55.4	63.3	79.9	108.1	105.7	98.8	81.1	98.7	58.8	65.1	64.8	107.4	110.6	130.8	101.5	102.2	106.6	153	146.9	165.3	149.3	161.4	166	138	147.1	137.9	114.3	116.9	118	159.5	161.1	144	113.9	120.2	107.6
5-HETE	2.1	1.5	1.9	2.6	3.6	2.8	3.1	2.2	3.9	4.5	11.2	7.7	7.4	3.3	5.9	4.6	6.2	5.6	3	2.3	2	3.6	3.8	4	2.2	4.2	3.8	1.5	2	1.6	2.2	2.1	1.6	1.6	2	1.9
7,10,13,16,19-Docosapentaenoic acid	48.3	45.2	50.9	58.9	81.1	77.2	73.3	62.3	74.2	164.1	171.9	170.1	268.5	273.6	324.4	255.9	248.5	250.9	118.7	110	124.3	114.2	122.5	128.7	109.2	116.5	110.9	302.3	304.5	305.1	421.2	417.2	397.5	309.5	340.6	300.3
7alpha-Hydroxy-cholesterol	1.8	4.1	4	4.8	2.4	1.8	2.7	3.7	1	4.5	13.1	3.2	2.6	1.6	7	1.6	2.2	7.8	9.4	3.3	3.1	5.3	5	4.9	8	3.7	3.5	13.5	13.9	6.3	7.8	11.5	12.9	7.8	10.6	7.1
7-Dehydrocholesterol																																				
7-Oxo-cholesterol																																				
8(9)-EpETE	1.7	1.1	0.5	0.7	0.9	1.9	1	1.8																												
8-HETE	3.7	4.7	5.2	5.3	6.6	2.9	4.9	2.5	8.8	25.5	32.4	15.7	11.5	23.8	15.7	6.1	14.9	15.6	7.2	6.1	2	10.6	8.9	3.4	2.7	22.5	21	6.3	9	2.4	4.7	8.4	10.6	4.4	11.1	2.4
Adrenic acid	169.4	161.8	173	196.7	257.9	261.1	226.3	214.6	245.2	49.8	52.7	52.7	96.9	99.2	116.9	97.2	98.3	101.1	379.3	378.6	383.1	375	377.6	413.6	357.4	364.8	357	123.2	125.3	127.2	151.7	154.7	139.7	115.7	125	112.2
alpha-Linolenic acid	1.2	1.1	1.3	1.4	2	1.8	2.1	1.5	2	1.1	1.2	1.3	2.1	2	2.3	1.5	1.9	1.8	2.8	2.5	3	2.5	2.9	2.7	2.3	2.6	2.4	2.3	2.3	2.4	4.1	3.3	3.7	3.5	3.7	3.3
Arachidic acid	10.6	13.4	15.4	14.2	18.3	17.1	17.8	17.2	17.2	31.8	14.6	17	22.8	24.6	24.7	19.3	19.5	20.6	25.9	30	21.9	23.8	22.7	31.3	22.3	26.6	20.7	29	28.3	30.6	33.2	35.1	34.7	25.4	25.2	22.5
Arachidonic acid	3	2.7	2.2	4.1	3.3	2.6	2.7	2.7	2	2.6	2.4	4.1	4.2	4.1	2.8	4.3	2.6	3.7	3.8	3.1	2.7	5.4	3.8	4.5	2.9	3.5	3.2	2	5.4	3.4	2.3	3.3	1.7	3.5	3.9	3.5
Arachidonoyl-EA	0.8	0.8	0.8	0.8	0.6	0.6	1	0.7					0.7	0.8	0.7	0.9	0.7	0.8	0.7	0.7	1.4	1	1.1		1.3		0.7	0.7	0.7	1	1	0.7		0.8	0.8	1
Behenic acid	1.4	1.5	1.8	2	2.1	2.2	2.4	2.4	2.4	2.4	2.3	2.6	3.5	3.9	4.1	3	3.1	3.3	3.8	3.8	3.4	3.2	3.4	3.9	4.2	3.9	3.8	5.5	5.4	5.8	6.9	7.3	7.1	5.2	5.4	4.9
Bishomo-gamma-linolenic acid	7.2	6.4	7.2	9.6	12.8	11.9	11.3	8.9	10.7	11.8	13.2	12.5	18.8	17.4	20.7	16.4	18.2	17	17.3	16.4	18.2	15.6	16.5	16.7	16.7	17.2	16.4	25	24.4	24.4	34.9	35.5	31.8	29.3	30.3	28.3
CE(14:0)	0.4	0.3	0.7		0.8	0.5	0.4	0.5	0.7	16.2	10.2	18	14.3	26.6	40.8	19.5	26.5	17.8	2.8	4.5	2.5	2.3		2.9	4.2	3.7	2.7	108.5	93.9	75.9	58.6	85.1	72.6	47.4	79.7	87.3
CE(14:1)	0.3										11.3	7.9	10.2	13	19.1	10.8	10.8	12	0.6									30.8	33.7	23.1	39.7	41.1	47.5	20.4	29.1	26.3
CE(16:0)	14.1	20.3	16.3	24.1	55.8	38.2	22.6	26.8	38.5	145.7	176.8	228.5	101.1	148.6	135.1	133.4	122.2	94	98.1	94.6	127.5	80.5	61.7	94.6	67	50.2	85.8	450.6	394.8	359.6	238.5	373.1	428.9	275.5	283.8	277.3
CE(16:1)	2.6	3.9	4.2	8.2	13.9	8.2	5	8.6	5.7	111.7	118.9	115.1	203.8	158.8	258.2	213.2	194.1	140.8	54.7	43.3	52.7	35.3	20.7	42.2	18	16.1	25.8	287.9	285	248.8	256.8	376.2	359.1	263.9	273	245.7
CE(16:2)	0.2	0.4	0.8	1.1	1.8	1	0.6	1.2	0.6	24.4	29.9	48.2	66.7	48.7	75.2	72.4	65	45.3	12.3	8.8	8	6	3.7	8.9	3.2	2.3	3.5	80.4	69.5	75.8	84.9	109.4	108.9	81.2	75.5	65.8
CE(18:0)	7.8	6.1	5.5	9.6	11.3	18.3	7.7	14.6	8	70.5	78.5	103	64	107	73	92.5	68	61.5	55.5	61.5	70	43.3	25.8	45.2	31.1	25	22	180.9	163.9	158.4	191.4	136	119	89	108.5	94.5
CE(18:1)	31.3	41.4	43.3	123.7	98.2	190.1	61.6	104.1	60	998.2	1730.9	1284.9	439.6	945.1	1640.6	1497.3	1412.3	934.5	876.1	684.9	780.5	546.9	309.5	605.3	257	214	350.4	2670.7	2352.1	2038.9	1927.4	2500.8	1938	1348.6	1470.7	1587.6
CE(18:2)	4.6	7.8	8.5	31.5	15.1	33.6	5.3	10.2	17	142.7	131.4	171	171	229.9	256	228.8	197.1	151.8	258.2	166.5	219.7	139.3	60.7	139.3	51.3	44.1	66.4	318.3	291.1	267.3	306.9	364.7	371.5	241.2	228.8	240.1
CE(20:0)	0.3	1.2	0.8	1.5	2	2.6	1.2	1.6	2.2	10.9	16.9	11.9	12	9.2	26.3	12.7	12.4	8.1	6	6.2	7.5	5.6	3.8	4.6	2.2	2.2	2.6	11.2	11.2	7.7	11.8	10.1	14.9	6.9	5.7	4.5
CE(20:1)	0.9	0.6	1	1.6	2.7	2.4	1	2.6	1.2	14.1	17.4	32.7	8.2	20.5	11.5	15.8	15	15.7	14.2	12.8	12.3	5.2	4.4	9.6	2.9	3.1	5.9	17.7	29.9	22.4	21.1	25.6	35.5	17.5	21.4	22.2
CE(20:2)	4.2	1	1.6	3.3	4.6	2.6	2	3.5	2	26.7	24.4	19.8	18.7	22.2	23.8	24.6	22.8	18.7	27.5	22.4	26.6	14.9	9.2	21	8	9.2	13.5	47.4	41.8	30.8	47.9	50.6	40	30.8	31.6	28.8
CE(20:4)	0.3	8.1	8.2	21.2	25.1	36.8	11.2	16.9	9.3	62.9	220.4	268.3	191.2	188.6	125.4	491.4	227.1	440.9	491.4	227.1	440.9	227.1	61.5	191.2	48.2	31.7	50.6	241.7	241.7	207.2	203.2	256.3	240.4	201.9	200.5	191.2
CE(22:1)	0.6	0.3	0.4	0.5	1.6	1	0.4	1.3	0.5	7.8	10.9	17.5	5.6	13.5	9.1	10	14.6	8.5	8	4.4	10.5	4.5	1.7	4.9	1.9	1.7	2.2	17	16.9	13.9	13.5	17.4	15.3	11.8	15	16.9
CE(22:6)	0.1	4.9	4.1	11.4	7.6	15.1	6.7	9.5	3.8	65.5	70.5	284.2	61	224.4	243	223.1	265.6	155.4	176.6	82.5	148.7	101.5	30	78.6	19.8	17.5	24.3	349.3	298.8	276.2	351.9	314.7	334.7	247	269.6	264.3
Cer(d18:0/16:0)	153.1	243.2	191.5	264.7	273.3	231.4	210.6	188.2	293.7	97.4	456.1	333.1	352	541.3	538.5	297.3	241.1	434.1	257	346.2	248.1	237.7	236.1	246.9	282.7	273.2	301.6	456	469.1	378.5	513.8	390.9	679.3	571.3	389	602.7
Cer(d18:0/18:0)	22.2	11.6	14.7	19.9	26	11.9	14	17.6	14.6	8.6	9.2	26.3	14.6	23.3	25.7	13.8	18.4	21.1	22.6	30.2	24.1	16.7	18.3	17.2	20.7	22.6	18.2	25.8	34.1	35.1	25.1	70.2	45.4	23.7	18.8	29.1
Cer(d18:0/20:0)	5.2	5.2	9.2	10	2.9	3.5	3	6.5	5.9	6.8	1.5	1.5	3.6	16.2	14.5	4.5	3.3	5.9	7.3	14.1	9.3	7.1	10.8	10.2	8.1	11.5	12.4	12	14.6	15.9	10.7	12.8	17.8	14.7	8.4	13.3
Cer(d18:0/22:0)	16.1	9.4	11.4	20.5	10.6	22.8	18	15.4	14.9	21.5	5.9	14.3	14.6	33.4	29.5	17.1	10.5	33.3	19	32.4	24.7	16.7	23.9	22.6	24.3	20	21.4	72	38.9	43.4	37.9	34	62.1	42	29.8	35.6
Cer(d18:0/24:0)	15.3	10	9.8	23.8	23.7	13	6.9	19.7	19.5	9.5	52.5	41.2	23.3	41.7	35.8	30	10.8	30.6	28.6	13.8	14	23.7	13.8	25.7	32	27.8	29.3	44	40.7	38.8	39.6	81.6	61	42.3	51.6	39
Cer(d18:0/24:1)	54.8	31.6	74	91.9	63.5	57.1	52.7	72.3	73.3	45.2	90.8	107.6	114.4	185.7	177.7	82.7	68.3	145.9	91.4	73.7	42.9	88.9	84.8	93.7	81.9	85.1	70.4	130.4	162.5	168.1	155.3	108	210.3	204.7	189.3	131.4
Cer(d18:0/26:0)	0.5		0.1	0.7	1.8	0.1	0.3	2.7	1.4	1.4	0.4	2.6	0.1	3.9	1.7	0.2	0.1		0.1	1.5		1.6	0.8	1.3	0.3			1.5	2.7	1.7	3.1	4.9	5.4	1.4	4.8	0.5
Cer(d18:0/26:1)	2.6	2.6	2.4	4.8	5.5	0.3	3.7	1.1	1.4	0.9	2.6	7.2	3.8	8.8	2.2		3.1	2.9	1.8	4.1	3.3	6.1	3.2	6	0.9	4.9	4.6	2.2	6.9	2.4	1.7	19.2	2.8	4.3	4.1	1.7
Cer(d18:1/16:0)	343.3	334.9	345.3	421.8	386.2	402	419.3	446.7	462.6	134.3	448.4	391.8	490.4	465	462.3	531.7	454.7	493.9	383.7	365.5	363	412.9	389	378.3	430.3	467.6	489.4	406.7	494.9	426.2	566.8	496.9	672.9	644.1	662.2	659.1
Cer(d18:1/18:0)	16.8	15.7	16.5	16	14.1	16	13.8	12.3	13.8	3.2	12.2	8.7	16.2	10.7	14.4	12.1	13.8	11.5	13.5	14.5	16.7	14.9	15.4	15	15.8	16.5	16.6	17.5	11.2	14.4	17.8	46.3	19.4	16.8	15.1	17.3
Cer(d18:1/20:0)	5.8	6.7	6.1	4.4	4.8	6.5	7.5	6.3	5.5	1.7	5.3	3.4	8.9	7.1	7.2	6.6	5.8	6.3	7.7	5.9	6.3	6.2	5.6	6.1	6.6	6.8	7.2	8.1	10.7	7.4	7.9	11	9.5	9.9	8.4	8.2
Cer(d18:1/22:0)	36	33.6	33	34.9	36.8	37.3	40.8	44.3	40.9	51	13.3	40.8	50.1	42.8	50.9	40.1	47.5	39.2	39.4	39.4	42.2	45.7	41.4	39.6	45.7	43.3	42.9	45.3	54.9	66.1	58.7	61.4	69.4	59.1	65.3	72.1
Cer(d18:1/24:0)	92.1	87.8	103.9	102.4	110.9	113.8	117.5	113.8	133	41.2	130.6	133.8	121.6	122.9	131	108.2	108.7	110.5	126.5	106.3	112.7	111.6	122.9	119.6	130.1	139.4	130	156.2	168.4	209.4	200.4	183.7	221.5	185.9	193.2	181.1
Cer(d18:1/24:1)	540.1	516.8	565.2	542.9	625.7	599.1	618	583	694.2	317.7	669.8	618.6	669.4	620.4	644.7	677.7	611.6	590.5	454.2	566.3	577.5	570.8	580.6	532.1	662.9	602.7	609.6	587.4	533.3	637.8	705.4	694.1	786.7	680.2	693.7	727.3
Cer(d18:1/26:0)	2.9	2.8	2.9	2	2.2	3	3.3	3.3	3	3.1	5.5	4.4	3.1	3.2	2.3	1.8	2.3	3.1	1.9	3.1	2.9	2.6	3.1	3.3	2.5	2	2.7	2.5	2.4	4	3.1	12.4	3.6	3.9	3.6	2.6
Cer(d18:1/26:1)	6.7	5	6.5	5.8	9	4.6	8.5	6.4	6.2	24.2	5.7	10.2	9.7	9.3	8.2	8.5	8.8	5.6	5.2	7.3	6.5	5.6	7	10.3	8	6.5	6.9	9.5	7.7	15.9	10.9	67.6	9.4	6.5	14.4	8.7
Cerotic acid	0.4	0.4	0.4	0.7	0.6	0.5	0.6	0.7	0.8	0.6	0.6	0.6	0.6	0.8	0.7	0.5	0.6	0.6	1.1	0.8	0.7	0.6	0.6	0.7	1	0.8	0.7	0.9	1	1.1	1.4	1.3	1.9	0.8	0.8	0.8
Cholestenone	0.4	0.4	0.8	1		1.5				0.7			1					1.1																	2.5	
Cholesterol	8608.2	9353.6	8621.9	10862.8	15333.6	10251	10186.4	10508.7	12393.4	10169.3	9653.7	9843.2	9796.5	9379.7	12614.8	12065.5	12439	12022.1	14196.9	13443.8	13696.6	13579.4	12170.8	13215.7	13824.5	13884.3	13937.6	29649.1	27369.1	41150.6	42326.3	33207.4	32160.7	29794.4	29279.4	46907.7
cis-Erucic acid	33.1	31.9	39.2	39.9	58.5	55.1	55	48.2	49.1	54.2	53.6	55.9	77	87.7	86.1	79.6	75.2	77.3	71.4	77.5	77.6	69	70.8	74.1	72.1	77.7	66.9	97.7	99.2	120.7	112.2	137.9	111.7	79.5	91.4	75.9
CL(68:4)										0.1	0.1	0.1	0.1	0.2	0.1	0.1	0.1	0.1										0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1
CL(68:5)									0.1	0.2	0.2	0.2	0.3	0.3	0.3	0.3	0.3	0.3										0.3	0.3	0.3	0.4	0.3	0.4	0.3	0.3	0.3
CL(70:4)	0.1	0.2	0.1	0.2	0.2	0.2	0.3	0.2	0.2	0.2	0.3	0.3	0.3	0.4	0.4	0.3	0.3	0.3	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.3	0.3	0.3	0.2	0.3	0.2
CL(70:5)	0.1	0.1	0.1	0.2	0.2	0.2	0.2	0.1	0.2	0.5	0.5	0.5	0.8	1	0.9	0.6	0.6	0.6	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.5	0.5	0.5	0.6	0.7	0.7	0.6	0.5	0.6
CL(70:6)	0.4	0.4	0.4	0.6	0.6	0.6	0.6	0.6	0.6	0.8	0.7	0.7	0.9	0.9	0.9	0.7	0.7	0.7	0.5	0.5	0.5	0.4	0.5	0.5	0.6	0.4	0.4	0.9	0.9	0.8	1	1	1.1	0.9	0.7	0.8
CL(72:4)										0.1	0.1	0.1		0.1	0.1	0.1	0.1	0.1											0.1	0.1	0.1	0.1	0.1			
CL(72:5)	0.4	0.4	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.4	0.4	0.4	0.7	0.8	0.8	0.5	0.5	0.4	0.5	0.6	0.5	0.5	0.5	0.4	0.7	0.5	0.5	0.1	0.3	0.3	0.3	0.5	0.4	0.3	0.5	0.4
CL(72:6)	0.7	0.6	0.7	0.9	1.1	0.9	1.1	1.1	1.1	1.2	0.9	0.8	1.3	1.3	1.3	1	0.9	0.9	0.9	0.8	0.9	0.9	0.8	0.8	0.7	0.9	1	0.9	1.2	0.9	1.4	1.5	1.3	0.9	0.9	1.1
CL(72:7)	1.3	1.5	1.4	1.8	2.1	1.8	1.6	1.7	1.5	0.8	0.7	0.7	1	0.9	0.8	0.6	0.6	0.7	1.4	1.3	1.4	1.3	1.4	1.5	2	1.3	1.3	0.8	0.9	0.9	1	1	1	0.7	0.6	0.7
CL(72:8)	1.9	1.8	1.7	2.3	2.1	2	1.8	2	1.9	0.4	0.4	0.4	0.4	0.5	0.4	0.3	0.3	0.3	1.6	1.5	1.5	1.3	1.4	1.4	2.2	1.5	1.6	0.5	0.5	0.4	0.5	0.5	0.6	0.4	0.4	0.4
CL(74:6)	0.1	0.1	0.1	0.2	0.1	0.2	0.1	0.2	0.1				0.1		0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.2	0.1	0.2	0.1				0.1			0.1		
CL(74:7)	0.3	0.3	0.3	0.3	0.4	0.4	0.2	0.3	0.3	0.1	0.1	0.1	0.2	0.1	0.2	0.1	0.1	0.1	0.3	0.3	0.4	0.3	0.3	0.3	0.5	0.4	0.6	0.1	0.1	0.1	0.1	0.2	0.1	0.1	0.1	0.1
CL(74:8)	0.5	0.5	0.5	0.8	0.6	0.6	0.6	0.7	0.5	0.3	0.2	0.3	0.4	0.4	0.4	0.2	0.3	0.3	0.6	0.4	0.5	0.4	0.5	0.4	0.6	0.5	0.4	0.3	0.3	0.3	0.4	0.4	0.4	0.2	0.3	0.3
CL(74:9)	0.6	0.5	0.6	0.7	0.7	0.7	0.7	0.7	0.6	0.2	0.2	0.3	0.3	0.3	0.3	0.2	0.2	0.2	0.5	0.5	0.6	0.5	0.5	0.5	0.6	0.8	0.6	0.3	0.3	0.3	0.3	0.3	0.4	0.2	0.2	0.3
Coenzyme Q9	30	24	21.2	42.7	38.3	46.9	44.3	44.2	42.3	26.5	24.1	28.1	32.9	35.3	32.6	28	29.6	34.4	43.1	49.6	44.3	46.2	42.1	43.6	40.5	40.8	42.5	11.5	12.5	8.9	24.4	21	25.4	14.4	18.8	14.6
Desmosterol	109.278	66.725	71.997	78.319						54.065	95.618	94.509	64.233	76.17					77.267	71.551	97.07	47.622	54.883					213.208	506.181	338.763	362.582	321.516				
DHA	118.4	112.7	125.2	121.9	164.7	159.8	157.5	138.8	159.8	216	221.9	221.3	330.9	333.7	398	307.8	300.3	298.3	243.1	227	255.5	242.8	255.8	270.1	250.4	263	259.8	464.9	457.7	458.9	562.1	556.2	524.3	484.7	534.8	463.9
Dolichol-18	1.6156	1.6156	1.8464	2.0772	2.308	2.0772	2.0772	2.0772	2.0772	2.5388	2.308	2.7696	4.1544	4.1544	3.6928	3.2312	3.0004	3.0004	2.308	2.308	2.5388	2.308	2.0772	2.5388	2.5388	2.308	2.308	2.5388	2.7696	2.7696	3.9236	4.1544	4.1544	3.462	3.462	3.6928
Dolichol-19	1.387	1.387	1.6644	1.6644	1.9418	1.9418	1.9418	1.9418	1.9418	1.9418	1.9418	2.2192	3.3288	3.3288	3.0514	2.774	2.4966	2.4966	2.2192	2.2192	1.9418	1.9418	1.9418	1.9418	1.9418	1.9418	2.2192	1.9418	1.9418	1.9418	2.774	3.0514	2.774	2.4966	2.4966	2.4966
Dolichol-20	0.3036	0.1518	0.3036	0.3036	0.3036	0.3036	0.3036	0.3036	0.3036	0.3036	0.3036	0.3036	0.4554	0.4554	0.4554	0.4554	0.4554	0.4554	0.4554	0.3036	0.3036	0.3036	0.4554	0.3036	0.4554	0.3036	0.3036	0.3036	0.3036	0.3036	0.4554	0.3036	0.3036	0.4554	0.4554	0.3036
EPA	8.7	7.8	9.1	11.1	15.4	12.8	14.7	10.1	12	51.3	62.7	57.9	114.5	94.4	116.8	76	97	84	32.4	27.1	35	27.6	26.6	25.5	20.4	20.4	20.6	191.6	184.2	193.8	281.4	288.7	260.1	267.3	286.4	252.5
gamma-Linolenic acid	17.3	15.4	16.8	25.7	33.4	29.7	27.4	23.2	27	29.3	30.9	29.4	60	54	51.4	36.3	40.4	37	42.5	41.1	42.7	38.7	38.7	40.4	36.4	36.8	35.5	60	58.3	58.9	71.4	74.4	78.6	92.9	97.7	86.8
GlcCer(d18:0/16:0)	48.9	100.2	67.1	91.1	146.7	108.3	51.8	19.4	83.5	35.2	39.8		57.9	118.4	59	84.6	116.1	42.6	157.1	54.1	41.9	107.9	86.1	87.9	33.5	135.8	51.4	21.1	87.1	53	140.6	92.4	69.8	58.7	169.1	103.3
GlcCer(d18:0/18:0)	16.3	8.6			2.3		7.3		0.3		33.4			0.7	1.2				9.7			0.5	7.1			20.2		13.1					0.4		3.8	3.8
GlcCer(d18:0/20:0)		7	1.2	6.2	2.7	0.8	3.4		3.2	22.3	14.9		13.8		4.1	3.6		0.2		4.1		3.2		0.3	2.7		8.5			0.2	4.1	1	11.4	0.9		4.6
GlcCer(d18:0/22:0)	7.8		27.3	17.5	16.2	10.6			12.7		20.5		0.2	10.9	23.8	11.5	8	32.1	2.1	12.2		12.7	16.6	14.4		6		60.5			14.9	5.6	3.3	43	5.5	14.9
GlcCer(d18:0/24:0)	5.6		41	12.9		36.4			6.9	33.9		6.5	17.9	7.4			47		2.7	7.2			8.9		2	4.3		11.1	8.6	144.3	16.7	10.1		6.1	32.3	26.2
GlcCer(d18:0/24:1)	31.8	29.9	23	66.9		56.3	59.6		56.7	46.7		12	37.6	47.1	22	23.3	36.1	21.6	35.6	41.4	35.8	52.8	5.8	11	37.7	56.7	22.4	50.5	18.1	19	23.8		27.1	37.5	30.7	64.4
GlcCer(d18:0/26:0)	5.9				1.3					7.1		36.4		2.7			2.7	2.3		3		2.5						53.3					5.7		4.8	1
GlcCer(d18:0/26:1)		2.5			1.4	1.6	8.2		4.6				5		1.6					2.1	2.7				3.6				1.3						1.7	1.5
GlcCer(d18:1/16:0)	608.3	710.5	754.8	838.6	916.7	771.9	819.1	656.3	840.8	225.1	866.3	840.7	1142.9	941.2	1094.5	688.9	687.5	845.9	838.6	891.3	904.3	854.5	865.3	871.5	768.2	657.7	722.5	714.7	583.3	545.3	844	897.6	932.5	688.2	716.3	702.6
GlcCer(d18:1/18:0)	21.9	16.8	13.9	20.9	18.4	19.5	14.7	20.7	26.6	4.6	29.7	28.2	38.5	29.5	31.1	25	24.2	16.5	14.6	18.2	23	20.7	18.3	19.7	23.4	22.7	24.1	23.6	16.3	17.1	17.3	18.6	24.6	10.2	16.6	13.9
GlcCer(d18:1/20:0)	10.8	7	13.6	8.1	13.2	10.9	14	9.1	11.2	5.2	16.9	13.4	13.7	14.3	18.1	10.4	16.2	8.6	13.3	10.1	10.8	24.7	18.2	11.7	10.8	14.3	13	8.7	14.8	13	12.8	9.6	9.4	11.2	10.6	8.4
GlcCer(d18:1/22:0)	97.9	111.5	111.9	120.6	126.9	157.4	112.3	142.7	124.1	58.8	186.3	190.3	179.8	143.1	134.8	134.6	118.3	107.2	110.8	129	121.3	190	125.4	115.4	146	126.5	170.3	222.6	104.5	146.2	114.4	143.4	131	118.6	145.2	126.3
GlcCer(d18:1/24:0)	237.8	207.9	231.3	250	260.6	330.1	267.6	234.7	264.2	395.3	110.9	381.2	301.7	233.7	218.2	214.7	240	211.6	284.3	246.9	213.6	428.2	271.9	254.2	285	459.3	297.7	441.5	328.8	231.4	277.2	270.5	257.5	237.2	292.1	221.3
GlcCer(d18:1/24:1)	591.7	696.8	598.7	724.7	737.5	881.4	701.7	740.2	733.7	784.7	829.2	259.6	813.7	970.6	798.5	736.3	579.2	683.3	639.2	750	769.6	872.7	718.6	731.8	781.5	700	848.6	560.9	658.5	587	664	620.5	672.5	521.1	606.7	548.8
GlcCer(d18:1/26:0)	5.6	5.6	5.7	2.5	5	3.3	3.8	1.7	1.9	2.3	2.1	8.2	2.9	2.5	2	2.8	1.4	3	3	2		5.1	4.4	2.4	2.5	4	2.2	4.5	8	1.7	1.7	2.8	3.1	2.2	1.6	1.2
GlcCer(d18:1/26:1)	8.8	8.1	4	5.7	5.4	7.3	8.9	6	3.4	5.1	10.4	2.2	5.5	9.9	4.3	2.3	5.7	6	4.7	7.6	6.5	5.1	8.1	3.2	5.1	8.9	6.3	6.4	6.9	3.3	6	3.3	5.7	2.1	3.9	3.3
Lanosterol	2.5	2.3	2.6	3.5	2.8	6.8	2.6	3.2	4.6	3.7	3.2	2.9	3.4	3.9	4	4.9	4.3	4.7	2.6	2.4	2.5	2.8	2.7	2.9	2.9	3.5	2.4	5.3	4.7		9.4	10.3	10.6		9	8.6
Lauric acid	6.3	16.5	2.5	5.8	23	3.8	8.1	1.8	22.6	12.3	10.2	17.7	23.5	23.7	23.2	22.9	18.7	18.2	5.4	5.2	4.2	19.4	2.8	5	4.7	6.1	3.9	19.3	17.7	24	31.4	30.8	31.2	58.5	45	38.6
Lignoceric acid	2.9	2.8	3.1	3.6	3.9	3.9	4.3	4.2	4.7	4.1	4.2	4.4	5.1	5.7	5.9	4.8	5	5.3	6.7	6.1	6.2	5.3	6	6.3	7.3	6.7	6.5	8.4	8.5	8.7	11.2	11.7	12	7.2	7.6	7.1
Linoleic acid	550.7	502	533.6	713.5	867.2	861.3	720.5	696.1	764.7	306.5	344.8	337	635.6	552.2	555.8	432.5	462.5	433.2	1080.4	1134.1	1065.5	1057.7	1092.1	997.4	1034.5	1042.1	1009.2	686.2	666.4	668.8	784.6	741.4	803.6	839.1	865.1	775.2
LTE4	7.6	5.6	4.3	3.4	5.4	6.2	7.9	3.6	3.8	4.9	3.7	7.5	5.9	6.7	4.4	6	5	6.8	6.4	3.5	3.5	5.1	3.6	6.5	3.6	5	4.4	6.7	7	7.6	3.7	7.6	6.8	6.9	7.2	8.2
Margaric acid	26	35.9	40.1	36.5	48.2	43.8	44.9	43	42.6	67.9	65	70.5	99.4	103.8	108	78.7	79.6	81.4	58.7	73.7	48.7	54.1	49.6	73.5	52.6	48	49	119.5	116.1	123.6	139	145.2	139.2	123.9	124.9	114.9
Myristic acid	61.9	85.1	89.9	89.1	110.4	97.6	105.9	102.7	99.6	213.6	212.2	217.7	326.5	338.8	367.7	260.4	264	263.6	129.8	136.5	109.5	128.3	116.4	142.8	128.6	114.9	118.9	384.8	374	384	441.1	429.9	430	440.6	477.2	408.6
Nervonic acid	2.2	2.3	2.8	2.4	3.3	3.5	3.7	3.4	3.3	3.1	3.1	3.5	4.2	4.8	4.6	4.5	4.3	4.3	5	4.7	5.4	4.4	4.9	5.1	5.1	5.9	4.6	7.2	7.2	8.4	8.6	10.6	8.5	5.9	6.8	5.7
Oleic acid	940.2	860.6	845.4	966.9	1034.2	1055.3	924.8	981.7	982.1	1207.6	1161	1137.8	1346.7	1289.7	1348.5	1274.3	1169.1	1164	1097.4	1144.8	1084.7	1074.9	1127.4	1138.1	1102.4	1081.8	1079.5	1318.1	1344.8	1301.6	1274.4	1264.3	1269	1291.1	1332.1	1269.6
PA(32:0)	10.9	11.2	11.2	12.9	13	12.2	10	7.4		4.7	4.1	5.6	4.5	8.3	7.7	7.1	6.3		10.9	9.2	8.7	6.2	8.4	9.1	9.2	8.1		6.2	6.2	6.6	5.5	8.4	7.8	9.4	9.1	
PA(32:1)	1.8	3.3	1.4	1.5	1.9	1.7	1.4	2.3		2.9	3.2	3.9	3.6	6.6	5.1	4.6	5.7		2.2	1.7	2.6	1.4	1.9	2.8	1.7	2.2		5.2	5.1	5.1	4.6	7.7	6	6.7	7.6	
PA(34:0)	9.3	15.8	9.8	11	7.2	8.9	9.5	8.6		4.7	4.2	3.8	4.2	5.5	5.1	4.9	6		7.6	6.8	7.8	6.4	6.1	6.8	8.6	7.2		7.4	6.4	7.6	7.7	8.3	8.1	7.6	8.3	
PA(34:1)	20.9	27.6	20.4	24.7	21.5	22.2	18	21.5		20.8	18.1	20.9	18.3	22.5	19.2	27.1	23.5		21.5	9.3	15.2	17.5	17	13.7	16.8	16.2		15.3	17.4	19	16.9	26.4	24.1	19.9	19.9	
PA(34:2)	7.4	6	5	7	4.7	5.5	4.7	5.6		4.7	5	5.1	4.3	6.6	5.4	4.4	5.1		5.6	5.2	2.6	4	3.6	4.6	4.5	4.6		4.2	4	4.2	4.9	7.1	4.9	5.5	6.2	
PA(36:0)	4.9	6.5	3.4	4.9	4.1	3.8	4	3.5		4.6	4.3	4.7	4.4	6.1	6.3	5	7.1		4.1	4.5	3.8	1.8	3.7	4.5	3.9	4.6		3.3	3.8	3.2	3.2	3.6	4.3	4.1	4.1	
PA(36:1)	35.5	21.7	29.1	26.1	22.4	23.4	19.3	20.6		22.1	17.6	21	19.9	17.5	16.6	25	22		20.3	22.4	12.4	26.1	17.8	20.8	19.8	21.3		17.5	20.5	20.4	18.3	20.4	24.5	21.1	26.6	
PA(36:2)	34.2	41.8	41.6	32.8	33.9	33.8	27.9	33.3		25.6	23.7	25.2	21.9	24.4	21	30.7	24.8		12.6	26.1	34.4	29.5	28.8	21.8	24.1	27.4		16.6	18.8	16.1	18.2	25.9	21.2	24	20.7	
PA(36:3)	5.8	8.9	6.9	6.3	7.2	5.9	8	6.7		3	6.3	4.2	7.3	9.7	8.3	6.3	7.7		4.5	5.8	1.7	7.2	3.6	4.7	5.7	4.9		4.6	4.9	5.4	5.4	7.7	6.2	6.3	8.3	
PA(36:4)	4.6	3.7	5.9	3.9	4	5.1	5.7	3.6		3	3.7	3.1	2.8	4.9	2.6	5.7	3.9		3.7	1.7	5.1	6.4	5.1	3.3	5.5	4.8		2.5	2.3	3.2	2.8	3.6	4.8	3.7	4.6	
PA(38:2)	3.4	2.7	2.8	2.4	2.9	2.3	2.1	2.6		2.4	2.6	2.8	2.7	2.8	3.3	3.7	3.3		2.4	1.1	2.5	1.1	2.7	2.6	2.3	2.5		1.6	1.9	1.8	1.7	2	1.9	2.2	2.6	
PA(38:3)	8.7	8.7	9.3	12.5	7.7	6.7	8.7	5.8		6.9	9	7	8.9	10.4	9.8	8	11.2		10.1	7.6	3.7	8.5	8.1	10	7.5	8.9		6.7	8.4	8.1	8.1	8.6	9.9	9	10.6	
PA(38:4)	28	27.7	18.3	19.8	19.3	18	23.6	17.4		11.3	12.2	13.2	13	16.4	16.7	15.7	17.8		20.7	29.1	24.4	11.2	23.1	18.3	22.4	24.9		14.3	15.2	14.5	14	18	17.3	13.3	19.5	
PA(40:3)	5.5	3.5	7.7	6.7	3.3	2.9	4.8	4.8		1.6	0.8	2.7	1	4.2	3.9	3.2	2.1		3.8	4.4	4.1	2.9	5.2	4	5.7	6		2.4	1.7	2.6	2.6	2.3	2.8	2.7	2.6	
PA(40:4)	27	22.7	27.8	23.9	18.8	19.8	14.6	20		3.8	6.7	6.1	3.2	9.1	9.8	9.7	9.6		21.8	34.3	27.5	14.5	31.7	17.8	24.5	23.8		6.3	7.7	5.7	5.7	6.5	8.7	9.5	7.7	
PA(40:5)	10.5	17.4	21.6	12	8.7	13.8	12.8	10.8		8.3	15.3	14.2	15.3	14.5	22.3	21.7	13		14.4	18.9	16.2	9.5	13.8	13.3	18.1	17.3		11.3	16.9	15.4	11.7	19.7	17.3	14.7	15.9	
PA(40:6)	12.3	13.1	18	13.3	11	7.2	8.6	8.6		9	11	9.3	10.2	13.1	11.9	19.5	21		8.4	13.9	12.6	6.6	11	8.3	12.4	13.8		14	14.5	14.5	16.6	19.9	16.7	16.5	17.1	
Palmitic acid	811	929.3	891.8	1016.8	1174.7	1209.9	912.9	1138.6	1063.3	1799.6	1483	1388.8	2207.8	2422	2584.1	1846.2	1576.3	1516.3	1356.9	1592.5	1233.1	1441.9	1228.4	1548	1342.4	1246.2	1264.3	2476.4	2457.9	2292.6	2254.8	2141.4	2269.7	2450.8	2753.6	2359.8
Palmitoleic acid	68.4	62.1	72.8	102.5	142.6	129.2	138.5	100.7	116.9	360	393.2	386.4	652.1	668.9	708.1	487.7	541.3	509.9	215.7	204.7	226.8	191.7	204.4	207.6	156.1	164.8	154.6	734.9	728.1	778.4	833.8	871.3	836.5	949.9	1045.3	881.5
PC(32:0)	57	55.4	57.4	44	51.8	43.1	50.7	45.1		39.4	40.5	38.8	35.6	43.2	45.1	40.3	42.5		46.4	55.2	38.1	50	73.2	54.2	46.9	55.9		43.7	42.3	43.1	40.7	49.6	61.7	47.2	49.6	
PC(32:1)	21.2	25	27.7	29.6	25.7	25	22.2	23		41.2	43.6	42.6	44.3	46.4	47.9	51.4	45		68.5	29.8	21.3	26.7	26.7	10.4	27.9	29.3		51.9	55.9	51.7	51.2	73.4	60	55.7	55.5	
PC(32:2)	3.2	3.8	3.3	3.7	3	3.7	3.2	2.9		7	6.8	6.1	6.4	8.3	7.3	7.2	6.8		3.5	2.6	3.5	3.8	3.5	3.6	2.3	4		7.9	9.1	7.8	8	8.9	10	8.9	8.2	
PC(34:0)	19.7	30.4	27.7	28.2	21.6	23.8	24.4	22.2		25.3	28.2	23.6	24.7	29.6	31.1	29.1	27.3		22.9	18.1	20.8	21.5	39	24.8	26.4	24.6		22.2	29.9	29.4	24.2	27.2	31.9	27.7	29.4	
PC(34:1)	49.5	62.5	63.5	40.3	44.5	48.9	44.2	40.9		49.3	43.8	43.8	46.4	44.3	50.4	52.8	51.8		37.5	48.7	58.2	46.4	42.1	66.9	54.3	49.4		58.9	57.6	59.2	51.5	59.2	73.6	68.5	57.5	
PC(34:2)	47.7	32.7	44.9	39.2	30.2	31.6	36	37.1		24.1	24.6	25.7	23.6	28	26.2	27.3	25.1		31.7	34.7	42.8	27.8	36.4	38.5	45.1	28.9		31.5	33.8	34.7	35.8	39.3	37	38.4	45.7	
PC(34:3)	4.9	4.2	5.3	3.5	3.8	4.5	4.1	3.7		4.3	4	4.2	4.4	4.9	4.3	4.6	4.4		3.9	4.4	3.6	4.4	4.2	6.2	4.6	4.1		5.6	5.5	6.1	5.3	6	7.6	6.5	6.3	
PC(36:0)	5.5	10.2	6.6	10.1	7.7	8.1	9.8	9.3		13.3	15.1	14.9	10.3	14.9	14.8	13	14.2		8.9	8.6	5.1	10.1	11.1	8	7.9	14.2		11.2	10.2	13.1	14.2	14.2	15.1	11.9	17.4	
PC(36:1)	55.7	43.9	60.1	38.1	46.9	53.3	48.1	47.3		59.4	54.9	57.3	59.8	67.7	64.7	60.5	69.4		45.4	46.9	38.8	97.9	48.1	55.8	74	49.2		67	70.7	59.9	66.8	73.5	76.4	98.8	75.3	
PC(36:2)	102.2	124	130.8	79.5	80.7	92.2	92.9	87.1		92.8	73.6	92.7	94.1	97.1	104.3	99.9	79.9		92.8	88.4	67.7	12.7	84.7	94.5	93.4	132.2		36	40.1	36.8	37.2	31.7	31.5	28.6	27	
PC(36:3)	52.4	97.7	83.3	67.1	52.9	53.1	57.2	60.9		43.6	40.5	38.6	39.8	47.4	46.4	46.8	40.6		58.1	64.1	48.9	61.5	62.9	60.5	87	52.7		51.7	51.7	56.1	56.6	72.1	56	64.2	58.8	
PC(36:4)	69.6	57.9	42.6	70.4	44.7	49.1	40.6	43.9		26	28	31.6	28.9	32	33	35.6	36.6		47.9	54.7	62.4	58.3	44.7	75.6	62	55.5		53.5	47.9	47.9	47.9	59.6	50.7	63.2	57.1	
PC(38:2)	23.9	12.2	13.2	14.8	12.2	15	14.7	12.9		15.1	13.8	13.7	13.5	16	16.3	16.9	18.2		9.8	8.9	7.7	13	13.7	18.1	11.9	11.2		13.9	15.7	13.7	12.8	14.7	15.2	18.3	15.9	
PC(38:3)	29	54.8	41.6	37.4	38.2	32.5	34.9	35		25.1	26	24.7	27.7	32.5	30.8	34.3	31.9		39.88	37.1	26.49	22.16	30.94	38.14	58.91	31.99		25.54	35.43	34.05	32.87	32.26	31.74	40.43	35	
PC(38:4)	91.89	120.91	74.52	61.26	82.34	78.9	70.18	68.1		45.34	44.85	48.51	40.61	50.97	56.97	58.35	52.19		82.41	69.2	57.85	90.56	78.79	76.06	15.97	82.2		70.63	58.31	67.09	66.64	72.33	86.9	68.51	69.68	
PC(38:5)	40.64	73.84	53.47	49.15	48.47	48.57	43.78	47.4		60.77	51.63	53.15	47.97	56.36	65.83	64.2	64.91		54.91	53.87	43.95	41.15	55.82	53.13	74.92	48.53		67.36	56.96	67.05	73.82	86.13	71.19	68.83	67.81	
PC(38:6)	65.88	60.53	55.59	49	58.47	52.71	60.12	52.71		63.82	67.53	63	63	63.82	62.18	63.41	63		65.06	55.59	69.18	64.65	56.42	61.35	84.82	66.3		73.71	83.59	90.18	79.47	93.88	112.41	86.06	84.41	
PC(40:3)	14.53	14.34	14.45	25.37	15.28	17.57	16.82	13.38		8.73	8.66	10.42	10.51	13.33	12.97	10.97	12.33		9.71	9.08	7.65	15.21	12	15.32	16.99	15.89		9.53	8.73	9.23	8.96	9.47	12.02	11.22	9.72	
PC(40:4)	40.92	35.72	40.86	69.35	43.93	37.14	42.39	35.7		17.25	18.5	17.81	15.03	20.69	27.47	21.06	24.25		25.9	32.1	27.21	35.37	32.38	46.7	36.26	39.3		18.61	18.12	15.49	15.88	18.05	19.39	19.56	18.65	
PC(40:5)	39.5	45.9	36.4	80.79	35.12	41.78	41.56	33.51		29.29	35.31	31.57	29.25	36.88	35.39	37.63	34.12		25.19	29.54	35.2	30.19	34.14	31.33	47.33	36.56		23.89	31.16	30.94	32.75	32.23	35.32	34.33	38.17	
PC(40:6)	36.51	42.86	65.31	46.23	40.69	38.91	40	35.14		70.8	55.2	58.17	60.57	64.05	65.66	67.6	30.23		44.12	35.03	31.48	40.23	43.43	40.29	45.66	59.66		54.97	71.66	62.85	66.97	69.15	76.46	64.29	59.37	
PC(P-36:0)/PC(O-36:1)	5.7	9.3	5.9	6.5	5.8	6.2	6.3	5.4		12.4	9.3	11.2	9.7	10.6	10	11.4	10.5		5.2	3.6	4.7	4.1	5.7	5	7.5	6		8.3	9.8	9.1	8.8	9.9	10.5	9.6	10.5	
PC(P-36:1)/PC(O-36:2)	18.8	16.3	16.3	15.5	12.6	15.2	13	15.6		21.1	18.4	19	22.9	21.5	20.4	18.8	20.4		9.3	12.5	12.1	10.1	11.5	19.5	14.7	13.2		17.5	18.6	18.4	19.7	22.6	20.4	26.8	19.3	
PC(P-36:2)/PC(O-36:3)	20.2	22.1	22.5	23.7	17.7	18.4	21.7	20.9		18.2	19.4	17.4	17.1	19.1	17.7	17.7	17.9		19.5	16	17.8	12.8	18.7	21.2	32.9	18.3		18.9	19.4	20.7	20.9	22.6	21	22.7	26.3	
PC(P-36:3)/PC(O-36:4)	36.4	38.5	32.4	34.7	34.3	28	33.9	28.9		21.5	21.4	23.7	21.1	23.5	23.8	25.1	26		29	38.2	34.9	26.4	41.5	30.5	58.3	32		32.9	32.8	29.8	35.9	38.7	34.9	44.5	33.2	
PC(P-36:4)/PC(O-36:5)	4.2	3.5	3.3	2.6	3.3	3.8	3.9	4.1		3.4	3.8	3.9	3.7	4.5	4.8	4.8	4.6		3.7	4	4	2.6	4.2	5.4	3.8	7.1		4.9	5.3	5.3	4.8	8	5.6	6.4	6.4	
PC(P-38:1)/PC(O-38:2)	3.2	3.1	3.7	6	3	3.5	3.3	3.2		5.2	4.3	5.3	4.8	4.6	4.3	5	4.6		2.6	1.6	2.7	2.3	3	3.8	3.5	3.2		4.1	3.8	3.5	3.9	4.3	4.1	4.6	4.1	
PC(P-38:2)/PC(O-38:3)	24.26	15.84	15.25	13.53	15.21	15.56	15.07	15.06		13.05	14.04	15.61	16.11	16.17	16.25	17.61	16.25		9.32	14.36	11.85	11.23	14.55	14.61	15.77	17.03		12.75	14.79	14.06	13.93	15.98	15.42	15.47	14.18	
PC(P-38:4)/PC(O-38:5)	55.86	49.89	52.1	50.74	44.88	52.92	45.02	54.6		43.78	36.05	39.68	33.78	43.72	42.41	47.77	46.33		62.58	51.33	39.52	45.08	62.78	55.57	43.43	51.23		53.68	46.57	50.69	52.91	56.79	55.69	54.99	69.04	
PC(P-38:5)/PC(O-38:6)	6.17	7.3	7.04	6.34	6.21	5.97	6.85	5.6		10.2	8.52	9.21	8.25	9.83	9.15	10.71	10.25		5.82	5.95	6.85	4.66	10.69	6.59	6.1	7.7		11.8	12.54	11.49	12.23	17.66	13.05	14.35	12.13	
PE(32:0)	6.62	7.64	8.02	10.16	10.81	10.23	10.92	9.2		7.2	7.33	7.05	7.79	8.83	9.1	8.98	7.38		9.29	9.44	7.95	11.08	9.96	8.58	9.18	9.13		7.48	8.66	8.11	8.5	11.72	9.96	11.41	11.24	
PE(32:1)	3.65	7.17	4.39	4.56	5.17	5.8	5.51	5.36		12.22	10.45	11.69	12.67	14.32	11.55	13.96	13.39		6.38	4.64	7.11	4.95	6.04	5.25	5.18	5.18		17.28	16.59	18.94	14.39	21.47	18.38	20.44	22.02	
PE(32:2)	2.45	1.89	1.46	1.29	1.12	1.54	1.47	1.83		3.09	3	3.03	3.57	4.18	4.3	4.28	3.65		1.3	1.92	1.29	1.15	1.97	1.47	1.97	1.82		3.39	3.59	3.39	3.59	4.72	4.07	5.13	4.87	
PE(34:0)	12.79	13.86	14.04	11.82	14.65	16.25	16.07	16.51		15.68	17.28	14.7	15.71	16.9	19.92	18.44	16.01		16.07	15.03	14.18	12.88	15.72	15.97	13.99	16.23		16.25	16.47	16.13	15.77	19.11	16.66	16.25	17.41	
PE(34:1)	37.18	41.56	45.95	40.85	49.85	49.86	45.22	48.59		49.49	54.37	52.56	51.64	58.27	52.08	58.52	57.89		42.8	40.32	50.18	47.63	44.8	45.57	42.73	44.71		45.95	52.27	54.59	50.45	65.63	57.58	69.36	68.1	
PE(34:2)	22.74	29.24	23.95	21.56	27.64	27.81	25.45	27.52		25.03	23.21	26.53	24.56	26.37	22.45	25.25	26.4		27.62	27.45	23.41	22.23	25	23.28	24.49	21.75		28.32	28.35	29.81	23.88	31.41	36.35	35.07	36.35	
PE(36:1)	61.41	54.1	52.16	43.96	44.97	44.43	39.55	40.94		50.08	45.79	52.67	53.09	34.97	36.66	40.45	31.9		51.88	49.84	57.83	48.28	41.06	39.49	43.65	44.67		58.44	53.53	53.26	53.21	47.25	59.84	56.53	59.42	
PE(36:2)	73.29	71.26	76.29	66.58	42.08	41.1	39.14	43.8		61.82	54.77	64.31	64.03	46.2	47.19	40.9	48.45		65.52	65.8	88.99	70.81	36.34	38.9	37.57	39.58		72.75	61.14	63.08	62.04	58.36	59.84	60.81	48.21	
PE(36:3)	39.98	35	38.16	37.27	70.22	80.08	67.56	75.53		36.6	43.32	39.71	41.24	64.9	59.59	71.36	66.8		33.26	42.02	41.31	35.35	69.08	69.08	66.04	62.62		44.69	42.33	48.42	45.26	80.85	69.08	85.77	83.88	
PE(36:4)	47.19	37.99	44.13	43.41	50.91	51.3	58.8	56.83		33.71	33.77	34.07	28.47	59.59	62.35	49.72	54.07		49.6	41.18	50.98	39.97	55.25	52.09	54.86	50.91		42.38	44.91	48.39	51.23	61.17	66.69	73.4	74.19	
PE(38:3)	46.49	69.69	78.39	72.05	63.32	54.94	51.08	59.74		40.32	46.22	45.57	44.38	50.28	50.36	42.78	46.18		64.12	61.88	62.12	60.01	53.99	59.85	60.25	62.91		55.14	67.57	56.85	55.57	71.29	64.88	56.45	59.44	
PE(38:4)	154.7	181.04	115.87	144.39	107.92	105	147.11	124.61		76.85	66.32	75.01	75.37	87.6	75.01	79.72	90.09		139.57	169.49	142.31	130.75	103.25	127.43	127.5	124.56		102.13	106.3	120.12	118.78	119.32	145.27	127.8	107.08	
PE(38:5)	38.99	32.04	30.52	35.41	26.89	33.41	30.25	27.25		44.14	36.17	45.58	45.96	51.43	50	44.18	46.05		32.34	38.2	40.68	30.25	31.56	32.2	30.3	31.08		64.05	61.14	58.32	69.87	69.14	80.45	78.85	64.06	
PE(38:6)	19.71	20.53	17.32		16.99	15.72	14.56	18.25		18.69	20.53	16.74	20.58	22.08	18.73	20	21.88		21.49	24.12	18.54	19.36	17.67	18.63	17.76	16.7		37.47	29.65	28.24	29.65	38.58	41.06	33.49	29.46	
PE(40:5)	38.41	44.48	38.66	26.88	27.17	28.32	38.85	34.11		21.33	25.1	23.79	25.79	29.23	25.83	28.57	31.33		41.41	38.77	37.41	33.52	33.96	28.38	35	31.88		30.42	31.43	38.15	30.32	34.15	32.27	32.19	38.93	
PE(40:6)	24.06	36.78	31.19	33.3	23.78	29.36	19.83	20.77		26.2	20.65	23.59	25.79	30.21	28.6	28.3	22.62		28.26	34.48	31.5	29.85	22.2	26.38	25.5	26.74		34.82	38.95	34.2	44.94	45.14	36.25	37.89	42.36	
PE(O-32:0)	4.53	5.88	4.35	10.82	5.42	5.59	4.93	4.49		6.69	6.42	6.39	5.9	5.79	5.49	6.8	4.95		4.35	8.24	3.84	4.38	5.89	4.3	9.74	5.55		9.37	12.15	10.34	10.64	10.35	9.45	9.99	10.04	
PE(P-36:0)/PE(O-36:1)	4.5	4.71	5.68	4.15	4.26	3.8	3.99	4.36		8.54	8.12	7.1	8.35	7.77	8.06	7.49	6.79		3.59	4.17	3.61	3.84	3.81	4.08	3.9	3.94		6.9	7.37	6.59	7.17	7.88	7.57	7.99	8.06	
PE(P-36:1)/PE(O-36:2)	10.82	9.34	10.84	8.47	7.24	8.6	7.6	8.51		12.25	15.02	13.32	14.44	12.16	13.44	13.21	12.37		6.61	7.15	7.92	7.25	7.76	7.41	6.88	6.78		10.41	10.69	9.59	10.45	13.96	11.91	14.68	12.64	
PE(P-36:2)/PE(O-36:3)	13.49	13.98	10.4	11.54	9.81	10	9.66	10.41		16.72	14.85	14.2	17.1	13.55	14.22	15.66	15.72		8	8.87	8.53	8.4	9.16	9.59	9.31	9.47		10.83	11.25	12.03	11.12	13.08	13.37	13.59	13.96	
PE(P-36:3)/PE(O-36:4)	24.02	16.69	23.63	23.8	19.63	22.85	19	17.78		24.51	20.33	21.81	18.23	22.08	26.26	19.5	21.67		20.38	20.98	22.06	20.05	23.02	18.4	20.72	21.14		15.7	14.61	16.53	15.76	16.97	18.41	20.17	18.24	
PE(P-36:4)/PE(O-36:5)	62.5	71.28	61.24	67.09	63.81	58.18	56.99	64.57		52.99	51.12	49.39	49.5	62.73	61.48	56.54	54.99		60.06	58.18	58.55	67.14	66.63	57.57	62.77	62.22		43.2	46.11	48.19	43.88	48.78	55.18	57.25	52.18	
PE(P-38:1)/PE(O-38:2)	6.01	5.15	5.13	5.9	3.9	4.99	4.86	4.68		10.03	6.98	8.09	9.21	7.82	7.35	8.45	8.37		4.31	4.31	4.06	4.94	4.44	4.65	4.29	4.98		7.34	7.02	7.77	7.03	7.62	8.51	8.71	8.01	
PE(P-38:2)/PE(O-38:3)	16.53	18.22	13.36	16.4	13.53	15.03	12.78	15.03		15.76	19.85	20.31	18.09	19.38	18.05	20.42	19.05		14.46	13.88	12.69	13.99	15.15	12.78	13.13	14.13		17.51	16.29	15.05	14.54	16.89	17.62	17.97	17.33	
PE(P-38:4)/PE(O-38:5)	123.97	116.2	113.31	136.27	118.26	105.79	120.45	105.03		86.6	96.81	86.42	83.61	97.71	101.25	104.46	113.29		101.86	118.56	129.1	119.65	115.07	111.89	119.51	101.85		79.75	73.54	91.88	78.67	87.07	96.81	94.19	87.87	
Pentadecylic acid	15.6	20.5	22.1	23.4	27.2	24.1	26.1	23.9	22.8	77.9	80.5	82.8	122.6	126	137.4	94.4	99.8	99.3	32.5	35.3	28.1	29.7	27.9	35.3	33.8	27.9	28.7	139.4	135.3	141.2	179	184.2	179.5	175.5	185.8	168
PG(34:2)	3.64	5.69	4.06	5.97	4.97	5.54	5.44	5.51		7.3	6.36	8.55	7.37	9.74	7.87	8	8.59		1.16	5.33	7.34	4.64	5.01	4.38	4.53	4.38		33.12	30.79	23.49	27.12	23.89	33.29	26.22	29.25	
PG(36:1)	12.98	25.64	44.63	104.91	12.85	15.17	7.45	10.16		41.42	30.93	28.86	29.21	32.69	59.47	40.73	34.47		41.02	10.26	12.09	8.28	13.29	12.45	14.1	20.26		86.03	80.99	108.55	108.49	88.42	73.97	100.73	113.65	
PG(36:2)	41.52	137.92	48.6	132.55	147	140.32	135.22	135.49		202.39	197.56	167.88	210.06	144.17	183.99	220.03	219.65		101.57	110.53	133.82	44.08	118.44	97.19	108.5	123.26		43.23	314.54	42.81	354.79	352.94	38.79	404.78	40.45	
PG(36:3)	118.95	32.31	157.12	102.08	127.44	117.68	115.65	119.99		93.19	78.17	93.6	89.06	100.4	94.11	84.99	81.16		90.27	133.48	124.71	98.31	87.56	85.11	109.66	104.87		134.93	145.57	116.23	127.25	172.24	167.13	146.32	127.59	
PG(38:2)	19.63	9.08	20.51	8.77	6.91	12.24	10.2	5.3		6.05	16.66	15.18	14.53	8.73	17.44	16.52	6.84		13.51	5.98	4.83	4.8	9.15	9.84	5.02	3.07		22.77	26.49	28.72	24.07	18.38	21.84	18.1	25.91	
PG(38:3)	53.39	18.21	53.15	15.31	18.38	19.39	15.04	16.54		24.77	25.89	25.47	11.71	29.78	36.37	19.78	30.65		15.94	27.98	14.23	13.36	21.48	17.64	17.89	13.88		40.6	47.79	41.79	45.2	54	54.65	63.29	43.12	
PG(38:4)	71.78	38.95	109.33	31.34	34.84	45.89	43.66	32.93		57.82	51.65	46.46	48.14	82.05	30.88	63.4	58.8		79.28	34.75	39.52	39.18	53.8	40.32	46.99	41.61		166.89	173.92	83.22	89.09	146.45	118.76	97.68	124.44	
PG(38:5)	56.35	48.14	160.76	105.45	74.33	71.39	64.56	44.69		40.19	31.89	35.26	48.06	47.28	75.8	68.02	51.17		144.34	71.91	78.39	77.01	67.94	106.31	62.4	83.41		164.22	176.32	124.46	121.87	153.85	124.46	161.63	131.38	
PG(40:4)	4.11			3.12	2.88		2.79			2.08	2.11	1.84	0.01	2.1	0.27	1.66	2.48		4.26	2.35	7.41	7.72	10.08	10.01	8.15	2.92			5.42							
PG(40:5)	115.63	116.51	72.54	61.28	61.49	67.24	69.82	63.11		34.39	30.5	33.33	36.63	40.74	48.8	44.92	51.31		62.62	48.86	36.94	51.4	47.59	59.94	62.77	50.37		54.52	58.44	63.73	51.94	40.97	60.95	62.65	58.16	
PG(40:6)	196.97	208.07	95.08	111.89	99.36	97	104.53	94.35		92.36	105.12	101.18	110.2	128.89	128.13	104.95	123.72		81.15	102.09	87.12	170.11	103.93	97.29	79.07	77.66		1.21	197.49	209.8	221.01	187.05	211.2	245	223.59	
PG(40:7)	112.91	121.34	288.09	236.23	111.6	116.96	106.61	108.18		124.77	144.58	146.07	161.8	162.57	161	134.05	176.92		113.75	111.35	128.47	226.24	93.28	126.35	91.87	122.99		420.1	427.57	465.76	481.85	379.77	490.59	494.58	444.18	
PG(40:8)	47.28	125.2	95.54	48.31	47.72	47.5	50.96	46.9		27.12	31.86	31.59	34.38	35.94	30.15	35.98	35.33		49.07	62.02	57.26	101	58.08	43.28	56.99	39.11		87.89	102.4	110.6	97.85	107.54	111.6	84.78	93.11	
PGD2	9.1	5.8	12.5	8	11.6	14.5	9	6.4	6.7	15.1	20.1	21.7	20.1	18.6	21.8	20.3	17	21.9	14.6	20.9	15.7	26.2	15.2	15.6	22	9.4	15.8	2.4	3.3	7.2	5.2	1.2	2.8	6	1.8	7.2
PGE2	11.3	8.4	14.8	15.3	14.6	15.5	8	11.5	8	16.4	15	9.3	17.4	24.7	16.8	17.6	14.3	18.5	29.1	42.3	28.7	29.8	28.5	26.1	25.2	34.9	34.8	3.4	3.6	8.9	2.9	4.5	2.2	3.5	2.2	5.3
PGJ2	3.7	1.2	2.3	2.2	3.7	3.8	2.4	1.4	2.5	0.2	0.7	0.8	0.1	0.2	0.2	0.5	2.3	0.4	2	2.7	5.2	2.6	2.4	1.9	1.9	3.3	1.7	2.4	2.3	2.9	2.2	2.5	2.1	2.7	1.6	2.1
PI(34:1)	5.89	5.71	4.45	4.62	5.28	5.54	5.1	6.1		6.23	7.92	6.7	6.87	6.6	7.27	7.18	7.49		5.12	7.12	5.41	4.54	5.83	5.47	4.8	5.04		6.69	5.71	6.05	6.49	6.59	7.51	6.02	6.82	
PI(34:2)	5.38	4.19	6.05	4.06	4.56	4.71	4.5	4.9		5.13	4.61	4.39	4.8	4.8	4.81	4.77	4.95		6.29	4.35	4.94	4.28	4.3	5.3	4.37	4.63		4.08	4.39	4.83	4.64	5.05	4.61	4.65	4.77	
PI(36:0)	1.17	1.01	1.34	0.91	0.95	0.9	0.89	0.89		1.59	1.43	1.71	1.66	1.47	1.49	1.3	1.65		0.48	1.03	0.83	0.79	1.14	1.26	1.28	1.18		1.18	1.31	1.47	1.29	1.33	1.09	1.27	1.1	
PI(36:1)	8.03	8.61	7.45	7.43	8.08	8.09	7.12	7.11		8.41	9.27	8.35	9.43	7.9	8.68	9.46	7.49		7.38	8	7.6	6.02	8.55	6.92	7.39	9.16		6.88	6.94	7.22	6.6	7.59	7.47	7.51	7.55	
PI(36:2)	17.51	17.25	20.87	20.07	18.72	18.15	21.71	17.19		14.7	16.59	14.38	16.16	16.17	14.08	15.6	15.16		21.88	16.12	21.94	23.78	20.79	16.45	16.14	19.97		13.13	14.16	12.45	13.34	13.58	14.4	13.45	15.67	
PI(36:3)	9.8	10.54	13.32	12.79	10.42	11.31	10.77	12.8		8.91	7.7	8.05	8.77	7.91	9.39	8.38	9.09		11.97	13.41	11.5	9.38	11.61	12	9.62	9.91		8.3	7.24	8.29	8.4	7.66	8.74	7.61	8.53	
PI(36:4)	8.91	9.51	11.21	11.16	11.75	9.81	9.59	10.44		7.52	8.39	6.92	7.75	7.87	9.13	10.01	9.26		12.15	16.25	13.01	10.31	9.59	11.34	10.09	11.82		9.99	10.54	11.1	10.21	12.01	10.7	11.08	10.64	
PI(36:5)	0.74	0.7	0.95	0.57	0.6	0.58	0.57	0.58		1.31	1.16	1.35	1.37	1.29	1.29	1.34	1.52		0.57	0.94	0.61	0.58	0.57	0.75	0.63	0.63		1.36	1.23	1.35	1.34	1.34	1.31	1.37	1.56	
PI(38:1)	0.23	0.1	0.32	0.33	0.27	0.28	0.21	0.33		0.29	0.48	0.16	0.4	0.24	0.38	0.32	0.42		0.07	0.28	0.31	0.03	0.21	0.25	0.19	0.33		0.04	0.15		0.03	0.02	0.15	0.13	0.1	
PI(38:2)	2.13	1.65	1.71	1.36	2.06	1.54	1.86	1.87		6.33	5.15	5.18	5.56	5.12	5.74	4.58	4.67		1.7	1.1	1.26	1.36	1.76	2.67	1.75	2.11		4.22	3.58	3.46	3.26	3.34	2.95	3.34	4.33	
PI(38:3)	25.94	22.23	24.85	21.95	20.32	15.48	25.3	17.61		35.59	45.37	39.06	36.81	37	29.87	40.29	35.99		16.32	14.14	16.02	20.63	22.59	34.01	31.93	19.08		36.95	34.05	28.43	33.51	34.72	29.14	29.97	37.96	
PI(38:4)	117.26	112.74	116.03	104.14	106.08	110.7	105.05	110.13		90.78	90.41	87.81	87.67	94.45	91.62	99.85	98.86		109.6	112.15	114.78	111.44	108.11	130.38	116.3	110.41		94.7	103.28	95.32	105.15	102.63	104.14	94.08	103.49	
PI(38:5)	13.95	14.45	13.01	13.69	12.02	11.84	15.24	12.83		20.86	22.44	21.08	20.15	27.28	21.66	23.97	25.21		15.31	16.06	15.5	12.39	13.18	11.5	13.89	14.2		21.38	20.67	23.05	23.47	23.37	21.06	22.84	22.14	
PI(38:6)	1.52	1.99	1.99	1.72	2.08	1.52	1.63	1.71		3.46	3.93	2.95	3.37	4.18	3.6	3.37	3.47		1.92	2.13	2.15	2.06	1.98	1.75	2.11	2.19		3.48	3.57	3.39	3.74	3.57	3.41	3.75	3.26	
PI(40:3)	1.1	1.51	2.29	1.32	1.9	1.29	1.34	2.2		1.32	1.15	1.15	0.93	1.12	1.09	0.81	1.17		1.41	1.12	0.94	1.37	1.12	1.85	1.93	1.36		1.23	1.17	1.1	1.11	1.15	1.05	1	1	
PI(40:4)	8.51	7.14	9.33	7.97	6.46	8.97	8.92	8.86		3.28	3.33	3.04	4.25	3.26	3.44	4.11	3.38		8.56	7.43	5.67	7.92	10.12	8.75	7.83	7.75		2.78	3.02	3.26	3.38	3.55	3.14	3.17	3.14	
PI(40:5)	4.72	4.81	4.96	4.49	5.29	4.27	4.48	5.1		5.82	6.4	5.65	5.97	6.67	6.1	6.15	6.34		4.1	3.64	4.15	4.45	5.27	4.77	4.74	5.21		4.5	4.66	4.13	4.61	4.17	5.34	4.86	5.07	
PI(40:6)	2.97	2.97	2.92	3.21	2.8	2.98	3.3	2.87		4.53	4.79	4.44	4.45	5.08	4.58	4.47	4.77		2.79	2.72	3.03	2.85	3.46	3.45	3.44	3.49		3.89	3.89	3.95	4.03	4.18	3.65	4.23	3.92	
PI(40:7)	0.87	0.93	1.03	1.11	1.11	0.88	0.87	0.88		1.65	1.67	1.45	1.44	1.87	1.58	1.77	1.54		1.05	0.79	0.58	1.11	1.01	1.14	1.12	1.19		1.11	1.1	1.35	1.31	1.13	1.39	1.11	1.12	
PS(32:0)	41.61	36.63	36.98	37.31	47.4	49.03	45.16	47.45		24	21.25	23.16	21.72	30.63	30.1	33.7	28.75		36.84	52.45	38.43	40.79	32.68	39.64	42.72	38.84		20.39	20.22	18.78	20.45	25.15	27.66	23.04	25.91	
PS(32:1)	7.29	6.31	7.29	5.99	8.04	9.22	8.27	7.13		16.2	15.33	14.62	14.54	18.72	17.22	18.48	21.95		7.37	7.8	10.13	6.93	8.63	7.53	8.71	7.72		13.83	15.52	15.25	15.41	16.2	17.69	16.08	17.89	
PS(34:0)	67.59	66.72	63.99	65.05	75.82	70.13	67.53	75.37		43.04	40.32	38.32	40.67	56.53	48.64	47.85	53.69		67.9	68	92.42	54.1	69.56	54.73	60.8	69.07		35.93	39.87	35.51	32.25	37.68	43.48	41.93	39.54	
PS(34:1)	109.58	93.47	94.13	107.26	102.26	102.25	112.1	113.58		111.23	102.8	107.15	117.07	127.41	143.05	120.45	128.88		102.33	94.62	144.16	85.45	95.37	99.35	85.06	81.08		110.82	106.09	103.89	97.31	113.66	133.14	123.66	111.49	
PS(34:2)	27.95	29.44	32.01	33.65	33.62	30.26	30.37	33.46		31.08	29.33	27.43	29.4	30.6	38.01	32.54	32.35		27.43	38.01	29.14	25.46	29.11	23.92	27.32	25.79		27.76	26.05	30	28.43	31.23	32.2	35.92	32.83	
PS(36:0)	30.66	38.46	48.29	35.06	30.96	32.36	24.07	36.08		37.8	48.67	42.19	53.27	46.6	50.75	48.72	47.69		45.24	34.33	33.88	29.39	42.17	38.74	47.23	37.42		21.17	29.22	27.98	34.44	29.11	45.93	27.72	24.93	
PS(36:1)	241.72	188.37	253.6	231.09	216.25	207.85	187.24	214.1		197.11	205.67	208.09	226.94	238.27	197.51	225.11	210.24		238.72	239.78	300.38	164.69	217.82	180.89	195.68	243.01		190.54	192.14	200.44	182.64	201.47	219.6	205.58	233.15	
PS(36:2)	241.43	247.22	263.55	243.24	242.68	213.1	225.19	242.65		151.9	146.69	143.97	162.51	156.21	145.25	175.34	153.17		179.03	224.83	309.65	242.45	182.7	217.51	159.86	225.97		130.23	139.3	145.48	149.16	175.22	152.78	162.51	163.77	
PS(36:3)	23.71	23.32	24.83	27.95	27.01	23.1	26.52	23.85		31.38	33.47	37.2	36.25	36.52	39.26	37.84	43.66		23.75	32.53	24.28	20.3	23.21	20.95	20.68	23.01		29.55	32.82	32.68	31.65	39.79	37.06	34.65	33.82	
PS(36:4)	15.56	15.38	24.45	16.47	17.37	15.94	17.44	15.06		12.22	14.79	12.96	13.17	17.73	15.73	15.41	14.54		19.27	16.99	25.01	15.06	13.63	17.27	17.83	14.54		16.75	14.79	16.15	15.14	18.11	17.13	15.76	16.53	
PS(38:0)	1.97	1.88	2.31	1.82	1.55	2.08	1.55	2.19		2.48	2.71	2.29	2.36	2.96	2.78	3.18	2.33		2.21	1.63	2.4	2.5	2.01	1.82	1.84	2.43		3.27	1.55	1.61	1.37	1.25	1.59	1.83	1.6	
PS(38:1)	9.4	8.2	6.57	10.06	6.43	6.7	6.93	7.83		6.64	7.52	7.07	7.74	7.27	7.66	8.73	9.47		5.69	8.91	7.64	7.52	9.3	6.35	7.06	9.63		8.02	7.29	7.49	7.14	6.8	8.48	7.92	7.51	
PS(38:2)	22.15	21.95	31.03	24.66	24.14	23.33	19.74	20.65		26.89	22.73	22.15	21.99	23.38	27.32	22.31	24.43		16.04	20.81	24.6	26.42	26.53	18.34	20.59	22.82		15.15	13.76	15.01	16.92	16.25	16.66	13.79	16.77	
PS(38:3)	88.31	79.42	71.34	69.54	52.26	69.26	73.36	64.22		75.4	83.59	79.07	74.49	89.67	94.46	85.34	95.51		88.87	92.36	77.81	58.18	68.51	76.51	93.79	75.31		74.99	69.21	67.5	71.29	72.22	80.18	69.39	70.96	
PS(38:4)	150.52	201.91	134.59	160.47	137.5	142.8	100.41	132.22		86.2	96.87	89.82	95.06	106.55	99.93	107.55	111.66		194.07	133.32	239.05	200.18	125.16	169.44	183.5	143.44		91.31	108.3	95.18	99.59	108.32	109.66	96.71	107.16	
PS(38:5)	34.2	21.2	16.6	19.89	23.1	19.7	20.8	24.61		39.07	36.45	37.96	39.03	42.4	45.57	40.82	49.53		17.85	23.58	26.55	28.01	20.53	22.23	21.95	24.85		34.43	33.28	32.81	39.63	39.19	35.19	38.91	36.74	
PS(40:2)	1.96	2.49	3.17	1.67	2.2	2.34	2.61	2.85		2.83	3.46	3.7	2.69	3.68	4.07	3.59	4.49		1.85	3.09	2.77	2.33	3.41	2.69	3.59	3.48		2.05	2.13	2.36	2.02	2.05	2.66	1.95	2.11	
PS(40:3)	20.4	20.19	27.82	19.38	20.1	24.17	18.66	24.86		11.19	14	15.38	14.95	21.29	23.11	14.95	20.72		31.87	23.01	27.6	26.82	42.58	46.52	38.43	29.52		9.79	12.31	12.83	12.43	13.6	12.01	11.08	12.68	
PS(40:4)	108.11	155.78	125.94	139.3	123.63	125.43	118.69	128.51		36.6	37.47	45.55	33.9	57.43	50.28	45.06	38.58		168.1	166.93	208.29	129.5	223.92	161.06	132.98	138.96		30.1	29.85	32.37	32.23	28.51	38.84	27.17	29.97	
PS(40:5)	53.56	50.12	68.04	56.23	50.85	49.38	49.98	40.87		67.83	59.93	67.34	68.34	83.45	76.71	91.18	80.48		69.22	48.97	62.2	71.35	80.99	59.47	48.92	52.72		44.97	46.47	46.03	46.59	47.93	53.05	59.23	57.41	
PS(40:6)	65.91	44.76	49.21	51.01	31.53	40.06	42.57	46.17		64.31	64.88	63.86	61.45	75.85	67.04	74.21	68.68		64.65	62.4	56.61	38.22	57.29	54.09	47.87	45.12		55.84	53.45	55.25	53.43	55.47	56.62	64.31	52.59	
PS(40:7)	3.14	13.14	4.77	5.9	3.3	6.59	4.24	5.97		14.55	13.85	13.78	14.18	15.4	16.04	18.1	15.78		8.67	4.11	7.05	8.01	4.02	6.99	6.71	7.96		10.13	11.03	11.32	12.81	11.75	11.03	12.61	10.83	
SM(d18:0/16:0)	1231.9	1355.7	1351.1	1569.5	1734.9	1746	1611.6	1740.1	1702.5	1437.8	479.9	1553.4	2020.8	1742.4	2005.5	1471.7	1498.6	1533.7	1414.8	1504.9	1467.5	1603.5	1620.1	1565.4	1561.2	1733.4	1464.8	1402.2	2284.3	1407.2	1763.8	1693.4	1874.4	1678.7	1702.7	1970.5
SM(d18:0/18:0)	26.6	23	26	29.1	27.2	32.3	30.6	30.5	30.3	38.5	30.1	9.7	40.1	33	41.8	29.6	32.6	29.3	23.7	22.3	26.2	31.4	27.2	24.3	33.2	26.8	32.2	28.3	29.8	52.2	29.9	35.1	31.5	37.1	27.6	34.2
SM(d18:0/20:0)	25.3	32.4	30.4	38.4	32	34.1	37.2	28.1	37.4	11.5	37	33.5	34	46.6	36.3	34.8	28.4	33.8	32	34.6	32.9	41.7	32.9	27.4	44.1	33.3	43.3	33.2	39.3	49.3	45.4	41.7	50.4	34.1	34.2	31.2
SM(d18:0/22:0)	34.5	30	25	35.9	36.8	45.3	35.3	38.9	33.9	40.4	35.8	17	37.5	31.6	43.1	34.6	31.1	29.4	29.4	26.4	34.1	34.3	50.6	35.7	45.6	39.3	35.2	130.5	32.9	40	43	40.5	33.9	51.6	41.2	37.8
SM(d18:0/24:0)	26.9	32.6	41.9	40.1	47.4	45.3	45.3	44.7	41	13	64.8	45.9	45.2	39.7	44.1	30.4	34	30.6	39.1	42.9	33.1	52.6	45.9	42.4	46.3	59.2	49.5	36.2	128	38.5	47.3	44.8	44.1	54.7	44.6	43.1
SM(d18:0/24:1)	785.1	671.7	720.3	871.4	923.4	1038.1	891.5	928.4	902.1	260.3	830	842.5	890.7	854.3	974.9	700.5	676.3	705.8	749.9	797.4	732.2	846.2	1044.4	856.3	944.6	1106.6	894.1	805.5	672.4	1787.8	881.8	845.2	866.5	988.1	800.8	831
SM(d18:0/26:0)	2.9	1.7	1.2	2.1	2.8	2.3	1.9	1.5	2.2	0.8	2.1	3	1.5	2.1	1.6	1.1	1.1	1.2	1.3	1.8	1.3	2.2	2.3	4.1	2.7	1.7	2.9	1.3	2.9	2	1.9	1.8	3.5	1.7	1	2
SM(d18:0/26:1)	4.2	3.9	6.3	5.2	5.7	7.2	4.7	5.3	5.8	1.4	4.1	8.9	4.8	4.2	4.8	3.3	3.9	3.3	3.6	3	4.6	5.5	5.6	7.4	8.7	4.7	5.9	2.6	14	3.9	3.2	3.9	4.3	2.7	3.4	3.8
SM(d18:1/16:0)	12333.3	11457	12031.3	13802.8	13981.8	16031.1	13221.5	14160.6	14605.3	13983.7	13583	4515.6	14881.9	16565.2	15510.2	13888.9	13117.6	12478.3	14077.7	14537.8	13434.8	14609.4	15284.6	14206.3	14786.6	16250	14184.4	11514.1	19168.6	12678.6	16479.8	16138.2	16241.1	14224.1	13717.9	13945.6
SM(d18:1/18:0)	171	158.3	169.9	168.7	174.3	203.4	183.2	192	192.1	214.6	71	209.3	260	229.5	228.2	180	197	187.9	177.7	172.3	163.9	171	208.9	176.2	181.6	222.7	192.1	170.4	389.1	196	196.1	214.2	207.4	199.7	206	204.1
SM(d18:1/20:0)	48.3	45.4	51.6	48.9	49.9	66.9	53.7	56.2	57.9	62.2	60.1	22.6	71.3	63.6	60.6	53	53	56.8	52.9	50.8	51.3	70.2	52.3	51.6	55	57	75.7	52.1	187.1	71	65	65.9	68.7	62.7	64.7	67.9
SM(d18:1/22:0)	336.7	337.5	299	359.2	373.4	451.3	365.8	383.2	390.8	435	455.5	160.1	469.6	405.5	459.2	334.8	357.4	361.8	339.3	349.6	309.6	530.1	387.9	387.7	556.8	400.7	417.7	473.2	1166.3	322.2	436.7	444.8	528.5	386.4	427.4	474.4
SM(d18:1/24:0)	774.8	846.7	882.8	912	962.5	1151.1	963.1	981.8	947.4	957.5	845.5	329.2	1000	846.5	1030.6	726.1	774.1	829.4	795.7	836.1	912.6	1219.5	949.2	968.3	1181.8	1010.6	1128	704.2	1893.8	888.4	930.5	924.4	1065	987.2	883.6	857.1
SM(d18:1/24:1)	4414.1	4333.3	3907.3	4542.3	4969.6	5805.1	4630.9	4927	4956.1	4514.2	4187	1543.5	5043.5	4448.8	4761.9	3665.2	4185.2	4117.6	4831.9	4521.7	4509.7	5748	5195.3	5119	5213.4	4929.1	5772.7	3352.1	6951.5	3857.1	4641.3	4157.3	4756.1	4288.8	4061.2	4401.7
SM(d18:1/26:0)	4.9	6.6	6.3	5.1	5.8	7.3	5.1	4.9	5.6	5.3	2.2	6.5	4.7	4	5.5	3.4	3.2	4.9	4	4.7	4.7	6.8	5.9	6	6.2	7.9	5.8	10.6	3.6	3.2	4.4	6.3	5	3.8	4.7	4.2
SM(d18:1/26:1)	24.1	19.3	21.4	22.9	24.4	29.8	23.1	24.4	23.3	18.8	20.4	8.3	21.9	23	19.4	18.9	20.1	17.8	20.2	20.7	18.4	29.3	25.4	24.6	26.9	23.9	28	18.3	15.5	41.1	18.4	18.9	22.5	18.5	20.9	20.1
Sphinganine	13.5	12.9	13.3	13.5	12.8	13.3	12.7	16	15.6	10.6	25.2	23.3	38.8	42	36.7	21.2	19.9	21.2	20	17.1		11.6	12.5	10.2	16	14.6	16.6	26	29.8	28.3	34.6	46	45.3	30.1	29.6	29.3
Sphinganine-1-phosphate	14	20.6	17.6	21.3	14	11.6	10.4	9.1	12	19.4	21.7	19.9	33.6	27.7	27.5	16.9	15.2	12.9	16.4	15.9		19.1	15.1	12.1	22.5	19	17.4	15.9	20.1	35.8	16.7	21.9	26.7	10	9.4	11.7
Sphingosine	236.3	292.5	262.6	221.8	209	221.3	178.4	244.7	226.8	265.2	216.4	293.7	505.6	411.5	443	279.5	295.7	294.3	287.9		241.7	215.3	271.2	188.7	311.2	283.1	257.4	252.8	337.3	438	274.1	447.6	540.8	263.1	294.4	263.1
Sphingosine-1-phosphate	384	579.9	461.9	335.4	307.5	446.2	209.5	307.7	238.2	339.5	401.2	382	685.8	484.4	545.3	347.7	235.5	337.3	504	343.2		387.9	293.4	274.3	472.5	426	360.2	275.5	448	711.4	238.5	504.6	614.6	232.4	191.9	141
Stearic acid	576.3	774	783.3	731.9	907.9	886.5	714.6	887.9	803.4	919.7	710.2	740.1	1196.2	1077.3	1212.5	940.7	789.8	784.1	1063.4	1375.4	860	903.4	1102.1	1347.3	1008.8	922	942.9	1431.6	1382.4	1380.5	1275.6	1160.9	1178.1	1134.1	1214.6	1021.9
Stearidonic acid	0.1		0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.2	0.2	0.2	0.3	0.3	0.4	0.2	0.3	0.2	0.1	0.1	0.2	0.1	0.1	0.1	0.1	0.1	0.1	0.2	0.2	0.3	0.6	0.6	0.4	0.6	0.6	0.7
Tricosanoic acid	0.7	0.8	0.8	1	0.9	0.9	1	1.2	1.1	1.5	1.3	1.4	2	2.4	2.4	1.4	1.5	1.6	1.6	1.5	1.4	1.4	1.4	1.7	1.7	1.4	1.5	3.2	3.3	3.3	3.8	4.1	4.2	3	3.2	2.9
TXB2	57.1	26.6	43.2	20.5	42.4	40.2	32	38.8	28.3	32.5	69.8	26.5	78.5	126.8	31.1	24.6	49	13.7	15.6	30	16	32.8	21.1	26.2	35.3	84.6	17	11.6	14.3	8.6	9.7	6.8	17.6	13.5	9.8	17.6
Zymosterol	0.408	0.211	0.399	0.412						0.425	0.547	0.467	0.061	0.08					1.292	0.533	0.52	1.033	0.515					6.557	4.517	7.302	5.947	7.853				
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name
10Z-Heptadecenoic acid
11(12)-EpETE
11-HETE
11Z,14Z-Eicosadienoic acid
12-HETE
12-Oxo-ETE
13,16,19-Docosatrienoic acid
13Z,16Z-Docosadienoic acid
14(15)-EpETE
15-Deoxy-delta-12,14-PGD2
15-Deoxy-delta-12,14-PGJ2
15S-HETE
2,3-Dinor-TXB2
20-HETE
22R-Hydroxycholesterol
24,25-Epoxycholesterol
24S-Hydroxycholesterol
25-Hydroxycholesterol
27-Hydroxycholesterol
4beta-Hydroxy-cholesterol
5,8,11-Eicosatrienoic acid
5-HETE
7,10,13,16,19-Docosapentaenoic acid
7alpha-Hydroxy-cholesterol
7-Dehydrocholesterol
7-Oxo-cholesterol
8(9)-EpETE
8-HETE
Adrenic acid
alpha-Linolenic acid
Arachidic acid
Arachidonic acid
Arachidonoyl-EA
Behenic acid
Bishomo-gamma-linolenic acid
CE(14:0)
CE(14:1)
CE(16:0)
CE(16:1)
CE(16:2)
CE(18:0)
CE(18:1)
CE(18:2)
CE(20:0)
CE(20:1)
CE(20:2)
CE(20:4)
CE(22:1)
CE(22:6)
Cer(d18:0/16:0)
Cer(d18:0/18:0)
Cer(d18:0/20:0)
Cer(d18:0/22:0)
Cer(d18:0/24:0)
Cer(d18:0/24:1)
Cer(d18:0/26:0)
Cer(d18:0/26:1)
Cer(d18:1/16:0)
Cer(d18:1/18:0)
Cer(d18:1/20:0)
Cer(d18:1/22:0)
Cer(d18:1/24:0)
Cer(d18:1/24:1)
Cer(d18:1/26:0)
Cer(d18:1/26:1)
Cerotic acid
Cholestenone
Cholesterol
cis-Erucic acid
CL(68:4)
CL(68:5)
CL(70:4)
CL(70:5)
CL(70:6)
CL(72:4)
CL(72:5)
CL(72:6)
CL(72:7)
CL(72:8)
CL(74:6)
CL(74:7)
CL(74:8)
CL(74:9)
Coenzyme Q9
Desmosterol
DHA
Dolichol-18
Dolichol-19
Dolichol-20
EPA
gamma-Linolenic acid
GlcCer(d18:0/16:0)
GlcCer(d18:0/18:0)
GlcCer(d18:0/20:0)
GlcCer(d18:0/22:0)
GlcCer(d18:0/24:0)
GlcCer(d18:0/24:1)
GlcCer(d18:0/26:0)
GlcCer(d18:0/26:1)
GlcCer(d18:1/16:0)
GlcCer(d18:1/18:0)
GlcCer(d18:1/20:0)
GlcCer(d18:1/22:0)
GlcCer(d18:1/24:0)
GlcCer(d18:1/24:1)
GlcCer(d18:1/26:0)
GlcCer(d18:1/26:1)
Lanosterol
Lauric acid
Lignoceric acid
Linoleic acid
LTE4
Margaric acid
Myristic acid
Nervonic acid
Oleic acid
PA(32:0)
PA(32:1)
PA(34:0)
PA(34:1)
PA(34:2)
PA(36:0)
PA(36:1)
PA(36:2)
PA(36:3)
PA(36:4)
PA(38:2)
PA(38:3)
PA(38:4)
PA(40:3)
PA(40:4)
PA(40:5)
PA(40:6)
Palmitic acid
Palmitoleic acid
PC(32:0)
PC(32:1)
PC(32:2)
PC(34:0)
PC(34:1)
PC(34:2)
PC(34:3)
PC(36:0)
PC(36:1)
PC(36:2)
PC(36:3)
PC(36:4)
PC(38:2)
PC(38:3)
PC(38:4)
PC(38:5)
PC(38:6)
PC(40:3)
PC(40:4)
PC(40:5)
PC(40:6)
PC(P-36:0)/PC(O-36:1)
PC(P-36:1)/PC(O-36:2)
PC(P-36:2)/PC(O-36:3)
PC(P-36:3)/PC(O-36:4)
PC(P-36:4)/PC(O-36:5)
PC(P-38:1)/PC(O-38:2)
PC(P-38:2)/PC(O-38:3)
PC(P-38:4)/PC(O-38:5)
PC(P-38:5)/PC(O-38:6)
PE(32:0)
PE(32:1)
PE(32:2)
PE(34:0)
PE(34:1)
PE(34:2)
PE(36:1)
PE(36:2)
PE(36:3)
PE(36:4)
PE(38:3)
PE(38:4)
PE(38:5)
PE(38:6)
PE(40:5)
PE(40:6)
PE(O-32:0)
PE(P-36:0)/PE(O-36:1)
PE(P-36:1)/PE(O-36:2)
PE(P-36:2)/PE(O-36:3)
PE(P-36:3)/PE(O-36:4)
PE(P-36:4)/PE(O-36:5)
PE(P-38:1)/PE(O-38:2)
PE(P-38:2)/PE(O-38:3)
PE(P-38:4)/PE(O-38:5)
Pentadecylic acid
PG(34:2)
PG(36:1)
PG(36:2)
PG(36:3)
PG(38:2)
PG(38:3)
PG(38:4)
PG(38:5)
PG(40:4)
PG(40:5)
PG(40:6)
PG(40:7)
PG(40:8)
PGD2
PGE2
PGJ2
PI(34:1)
PI(34:2)
PI(36:0)
PI(36:1)
PI(36:2)
PI(36:3)
PI(36:4)
PI(36:5)
PI(38:1)
PI(38:2)
PI(38:3)
PI(38:4)
PI(38:5)
PI(38:6)
PI(40:3)
PI(40:4)
PI(40:5)
PI(40:6)
PI(40:7)
PS(32:0)
PS(32:1)
PS(34:0)
PS(34:1)
PS(34:2)
PS(36:0)
PS(36:1)
PS(36:2)
PS(36:3)
PS(36:4)
PS(38:0)
PS(38:1)
PS(38:2)
PS(38:3)
PS(38:4)
PS(38:5)
PS(40:2)
PS(40:3)
PS(40:4)
PS(40:5)
PS(40:6)
PS(40:7)
SM(d18:0/16:0)
SM(d18:0/18:0)
SM(d18:0/20:0)
SM(d18:0/22:0)
SM(d18:0/24:0)
SM(d18:0/24:1)
SM(d18:0/26:0)
SM(d18:0/26:1)
SM(d18:1/16:0)
SM(d18:1/18:0)
SM(d18:1/20:0)
SM(d18:1/22:0)
SM(d18:1/24:0)
SM(d18:1/24:1)
SM(d18:1/26:0)
SM(d18:1/26:1)
Sphinganine
Sphinganine-1-phosphate
Sphingosine
Sphingosine-1-phosphate
Stearic acid
Stearidonic acid
Tricosanoic acid
TXB2
Zymosterol
METABOLITES_END
#END