#METABOLOMICS WORKBENCH araskind_20200318_123441 DATATRACK_ID:1944 STUDY_ID:ST001383 ANALYSIS_ID:AN002304 PROJECT_ID:PR000947
VERSION             	1
CREATED_ON             	May 19, 2020, 11:06 am
#PROJECT
PR:PROJECT_TITLE                 	Health impacts of endocrine disrupting chemicals
PR:PROJECT_TYPE                  	Observational study
PR:PROJECT_SUMMARY               	Investigating exposures and health impacts of endocrine disrupting chemicals
PR:PROJECT_SUMMARY               	among inner-city children.
PR:INSTITUTE                     	University of Michigan
PR:DEPARTMENT                    	Nutritional Sciences
PR:LABORATORY                    	Meeker Lab
PR:LAST_NAME                     	Meeker
PR:FIRST_NAME                    	John
PR:ADDRESS                       	Ann Arbor, MI
PR:EMAIL                         	meekerj@umich.edu
PR:PHONE                         	734-764-7184
#STUDY
ST:STUDY_TITLE                   	Investigating exposures and health impacts of endocrine disrupting chemicals
ST:STUDY_TITLE                   	among inner-city children.
ST:STUDY_TYPE                    	Observational study
ST:STUDY_SUMMARY                 	Our CHEAR project will conduct untargeted metabolomics analyses among children
ST:STUDY_SUMMARY                 	with and without asthma to gain insight into potential mechanisms related to
ST:STUDY_SUMMARY                 	asthma development. Metabolomics analysis will be conducted in a subset of
ST:STUDY_SUMMARY                 	participants from DISCOVER, a panel study enriched with low-income African
ST:STUDY_SUMMARY                 	American children in Baltimore, MD enrolled from 2009 to 2013. We will conduct
ST:STUDY_SUMMARY                 	untargeted metabolomics in serum collected from 15 children with non-atopic
ST:STUDY_SUMMARY                 	asthma and 22 non-atopic children without asthma. For each child, we will
ST:STUDY_SUMMARY                 	conduct analyses in two serum samples collected 3-9 months apart (total = 74
ST:STUDY_SUMMARY                 	samples). We will use these pilot data to explore differences in metabolomic
ST:STUDY_SUMMARY                 	profiles among non-atopic children with asthma compared to non-asthmatic
ST:STUDY_SUMMARY                 	controls, and leverage repeated sample measures to assess differences in
ST:STUDY_SUMMARY                 	metabolomic profiles among asthmatic children by symptom frequency or severity.
ST:STUDY_SUMMARY                 	Finally, these data will be used to explore differences in metabolomic profiles
ST:STUDY_SUMMARY                 	by exposure status after urinary organophosphate flame retardant biomarkers have
ST:STUDY_SUMMARY                 	been quantified by CHEAR. Together, these analyses will provide pilot data for
ST:STUDY_SUMMARY                 	future work in our Center to assess potential mechanisms related to asthma
ST:STUDY_SUMMARY                 	development and severity as well as effects of organophoshate flame retardant
ST:STUDY_SUMMARY                 	exposures.
ST:INSTITUTE                     	University of Michigan
ST:DEPARTMENT                    	Biomedical Research Core Facilities
ST:LABORATORY                    	Metabolomics core
ST:LAST_NAME                     	Kachman
ST:FIRST_NAME                    	Maureen
ST:ADDRESS                       	Ann Arbor, MI
ST:EMAIL                         	mkachman@med.umich.edu
ST:PHONE                         	734-232-0842
#SUBJECT
SU:SUBJECT_TYPE                  	Human
SU:SUBJECT_SPECIES               	Homo sapiens
SU:TAXONOMY_ID                   	9606
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data
SUBJECT_SAMPLE_FACTORS           	SU0036817	C-1NXX5-S-00	Gender:Male | Condition:asthmatic	Age (years)=9.4; Family ID=1001; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041078-P;20190723-EX00961-A003-IN0029-S00041078-N
SUBJECT_SAMPLE_FACTORS           	SU0036818	C-1NXY3-S-00	Gender:Male | Condition:asthmatic	Age (years)=9.4; Family ID=1001; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041079-P;20190723-EX00961-A003-IN0029-S00041079-N
SUBJECT_SAMPLE_FACTORS           	SU0036819	C-1NY02-S-00	Gender:Male | Condition:control	Age (years)=9.3; Family ID=1005; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041080-P;20190723-EX00961-A003-IN0029-S00041080-N
SUBJECT_SAMPLE_FACTORS           	SU0036820	C-1NY10-S-00	Gender:Male | Condition:control	Age (years)=9.3; Family ID=1005; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041081-P;20190723-EX00961-A003-IN0029-S00041081-N
SUBJECT_SAMPLE_FACTORS           	SU0036821	C-1NY28-S-00	Gender:Male | Condition:asthmatic	Age (years)=8.7; Family ID=1007; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041082-P;20190723-EX00961-A003-IN0029-S00041082-N
SUBJECT_SAMPLE_FACTORS           	SU0036822	C-1NY36-S-00	Gender:Male | Condition:asthmatic	Age (years)=8.7; Family ID=1007; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041083-P;20190723-EX00961-A003-IN0029-S00041083-N
SUBJECT_SAMPLE_FACTORS           	SU0036823	C-1NY44-S-00	Gender:Female | Condition:asthmatic	Age (years)=9.3; Family ID=1009; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041084-P;20190723-EX00961-A003-IN0029-S00041084-N
SUBJECT_SAMPLE_FACTORS           	SU0036824	C-1NY51-S-00	Gender:Female | Condition:asthmatic	Age (years)=9.3; Family ID=1009; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041085-P;20190723-EX00961-A003-IN0029-S00041085-N
SUBJECT_SAMPLE_FACTORS           	SU0036825	C-1NY69-S-00	Gender:Male | Condition:asthmatic	Age (years)=11.3; Family ID=1011; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041086-P;20190723-EX00961-A003-IN0029-S00041086-N
SUBJECT_SAMPLE_FACTORS           	SU0036826	C-1NY77-S-00	Gender:Male | Condition:asthmatic	Age (years)=11.3; Family ID=1011; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041087-P;20190723-EX00961-A003-IN0029-S00041087-N
SUBJECT_SAMPLE_FACTORS           	SU0036827	C-1NY85-S-00	Gender:Female | Condition:asthmatic	Age (years)=8.8; Family ID=1012; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041088-P;20190723-EX00961-A003-IN0029-S00041088-N
SUBJECT_SAMPLE_FACTORS           	SU0036828	C-1NY93-S-00	Gender:Female | Condition:asthmatic	Age (years)=8.8; Family ID=1012; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041089-P;20190723-EX00961-A003-IN0029-S00041089-N
SUBJECT_SAMPLE_FACTORS           	SU0036829	C-1NYA5-S-00	Gender:Male | Condition:asthmatic	Age (years)=6.1; Family ID=1014; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041090-P;20190723-EX00961-A003-IN0029-S00041090-N
SUBJECT_SAMPLE_FACTORS           	SU0036830	C-1NYB3-S-00	Gender:Male | Condition:asthmatic	Age (years)=6.1; Family ID=1014; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041091-P;20190723-EX00961-A003-IN0029-S00041091-N
SUBJECT_SAMPLE_FACTORS           	SU0036831	C-1NYC1-S-00	Gender:Male | Condition:asthmatic	Age (years)=12.3; Family ID=1015; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041092-P;20190723-EX00961-A003-IN0029-S00041092-N
SUBJECT_SAMPLE_FACTORS           	SU0036832	C-1NYD8-S-00	Gender:Male | Condition:asthmatic	Age (years)=12.3; Family ID=1015; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041093-P;20190723-EX00961-A003-IN0029-S00041093-N
SUBJECT_SAMPLE_FACTORS           	SU0036833	C-1NYE6-S-00	Gender:Female | Condition:control	Age (years)=12.8; Family ID=1016; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041094-P;20190723-EX00961-A003-IN0029-S00041094-N
SUBJECT_SAMPLE_FACTORS           	SU0036834	C-1NYF4-S-00	Gender:Female | Condition:control	Age (years)=12.8; Family ID=1016; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041095-P;20190723-EX00961-A003-IN0029-S00041095-N
SUBJECT_SAMPLE_FACTORS           	SU0036835	C-1NYG2-S-00	Gender:Male | Condition:control	Age (years)=8.8; Family ID=1019; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041096-P;20190723-EX00961-A003-IN0029-S00041096-N
SUBJECT_SAMPLE_FACTORS           	SU0036836	C-1NYH0-S-00	Gender:Male | Condition:control	Age (years)=8.8; Family ID=1019; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041097-P;20190723-EX00961-A003-IN0029-S00041097-N
SUBJECT_SAMPLE_FACTORS           	SU0036837	C-1NYJ5-S-00	Gender:Female | Condition:asthmatic	Age (years)=6.7; Family ID=1020; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041098-P;20190723-EX00961-A003-IN0029-S00041098-N
SUBJECT_SAMPLE_FACTORS           	SU0036838	C-1NYK3-S-00	Gender:Female | Condition:asthmatic	Age (years)=6.7; Family ID=1020; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041099-P;20190723-EX00961-A003-IN0029-S00041099-N
SUBJECT_SAMPLE_FACTORS           	SU0036839	C-1NYL1-S-00	Gender:Male | Condition:control	Age (years)=9.9; Family ID=1024; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041100-P;20190723-EX00961-A003-IN0029-S00041100-N
SUBJECT_SAMPLE_FACTORS           	SU0036840	C-1NYM9-S-00	Gender:Male | Condition:control	Age (years)=9.9; Family ID=1024; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041101-P;20190723-EX00961-A003-IN0029-S00041101-N
SUBJECT_SAMPLE_FACTORS           	SU0036841	C-1NYN6-S-00	Gender:Female | Condition:asthmatic	Age (years)=8.5; Family ID=1026; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041102-P;20190723-EX00961-A003-IN0029-S00041102-N
SUBJECT_SAMPLE_FACTORS           	SU0036842	C-1NYP2-S-00	Gender:Female | Condition:asthmatic	Age (years)=8.5; Family ID=1026; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041103-P;20190723-EX00961-A003-IN0029-S00041103-N
SUBJECT_SAMPLE_FACTORS           	SU0036843	C-1NYQ0-S-00	Gender:Female | Condition:asthmatic	Age (years)=9.4; Family ID=1027; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041104-P;20190723-EX00961-A003-IN0029-S00041104-N
SUBJECT_SAMPLE_FACTORS           	SU0036844	C-1NYR8-S-00	Gender:Female | Condition:asthmatic	Age (years)=9.4; Family ID=1027; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041105-P;20190723-EX00961-A003-IN0029-S00041105-N
SUBJECT_SAMPLE_FACTORS           	SU0036845	C-1NYS5-S-00	Gender:Female | Condition:control	Age (years)=12.3; Family ID=1028; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041106-P;20190723-EX00961-A003-IN0029-S00041106-N
SUBJECT_SAMPLE_FACTORS           	SU0036846	C-1NYT3-S-00	Gender:Female | Condition:control	Age (years)=12.3; Family ID=1028; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041107-P;20190723-EX00961-A003-IN0029-S00041107-N
SUBJECT_SAMPLE_FACTORS           	SU0036847	C-1NYU1-S-00	Gender:Female | Condition:asthmatic	Age (years)=10.4; Family ID=1030; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041108-P;20190723-EX00961-A003-IN0029-S00041108-N
SUBJECT_SAMPLE_FACTORS           	SU0036848	C-1NYV9-S-00	Gender:Female | Condition:asthmatic	Age (years)=10.4; Family ID=1030; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041109-P;20190723-EX00961-A003-IN0029-S00041109-N
SUBJECT_SAMPLE_FACTORS           	SU0036849	C-1NYW7-S-00	Gender:Female | Condition:asthmatic	Age (years)=10.1; Family ID=1038; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041110-P;20190723-EX00961-A003-IN0029-S00041110-N
SUBJECT_SAMPLE_FACTORS           	SU0036850	C-1NYX4-S-00	Gender:Female | Condition:asthmatic	Age (years)=10.1; Family ID=1038; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041111-P;20190723-EX00961-A003-IN0029-S00041111-N
SUBJECT_SAMPLE_FACTORS           	SU0036851	C-1NZ27-S-00	Gender:Male | Condition:control	Age (years)=12.8; Family ID=1049; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041114-P;20190723-EX00961-A003-IN0029-S00041114-N
SUBJECT_SAMPLE_FACTORS           	SU0036852	C-1NZ35-S-00	Gender:Male | Condition:control	Age (years)=12.8; Family ID=1049; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041115-P;20190723-EX00961-A003-IN0029-S00041115-N
SUBJECT_SAMPLE_FACTORS           	SU0036853	C-1NZ43-S-00	Gender:Female | Condition:control	Age (years)=12.9; Family ID=1051; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041116-P;20190723-EX00961-A003-IN0029-S00041116-N
SUBJECT_SAMPLE_FACTORS           	SU0036854	C-1NZ50-S-00	Gender:Female | Condition:control	Age (years)=12.9; Family ID=1051; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041117-P;20190723-EX00961-A003-IN0029-S00041117-N
SUBJECT_SAMPLE_FACTORS           	SU0036855	C-1NZ68-S-00	Gender:Female | Condition:asthmatic	Age (years)=7.4; Family ID=1059; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041118-P;20190723-EX00961-A003-IN0029-S00041118-N
SUBJECT_SAMPLE_FACTORS           	SU0036856	C-1NZ76-S-00	Gender:Female | Condition:asthmatic	Age (years)=7.4; Family ID=1059; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041119-P;20190723-EX00961-A003-IN0029-S00041119-N
SUBJECT_SAMPLE_FACTORS           	SU0036857	C-1NZ84-S-00	Gender:Male | Condition:control	Age (years)=10.8; Family ID=1085; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041120-P;20190723-EX00961-A003-IN0029-S00041120-N
SUBJECT_SAMPLE_FACTORS           	SU0036858	C-1NZ92-S-00	Gender:Male | Condition:control	Age (years)=10.8; Family ID=1085; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041121-P;20190723-EX00961-A003-IN0029-S00041121-N
SUBJECT_SAMPLE_FACTORS           	SU0036859	C-1NZA4-S-00	Gender:Male | Condition:control	Age (years)=11.0; Family ID=1086; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041122-P;20190723-EX00961-A003-IN0029-S00041122-N
SUBJECT_SAMPLE_FACTORS           	SU0036860	C-1NZB2-S-00	Gender:Male | Condition:control	Age (years)=11.0; Family ID=1086; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041123-P;20190723-EX00961-A003-IN0029-S00041123-N
SUBJECT_SAMPLE_FACTORS           	SU0036861	C-1NZC0-S-00	Gender:Female | Condition:control	Age (years)=7.8; Family ID=1123; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041124-P;20190723-EX00961-A003-IN0029-S00041124-N
SUBJECT_SAMPLE_FACTORS           	SU0036862	C-1NZD7-S-00	Gender:Female | Condition:control	Age (years)=7.8; Family ID=1123; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041125-P;20190723-EX00961-A003-IN0029-S00041125-N
SUBJECT_SAMPLE_FACTORS           	SU0036863	C-1NZE5-S-00	Gender:Male | Condition:control	Age (years)=7.3; Family ID=1143; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041126-P;20190723-EX00961-A003-IN0029-S00041126-N
SUBJECT_SAMPLE_FACTORS           	SU0036864	C-1NZF3-S-00	Gender:Male | Condition:control	Age (years)=7.3; Family ID=1143; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041127-P;20190723-EX00961-A003-IN0029-S00041127-N
SUBJECT_SAMPLE_FACTORS           	SU0036865	C-1NZG1-S-00	Gender:Female | Condition:control	Age (years)=9.7; Family ID=1158; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041128-P;20190723-EX00961-A003-IN0029-S00041128-N
SUBJECT_SAMPLE_FACTORS           	SU0036866	C-1NZH9-S-00	Gender:Female | Condition:control	Age (years)=9.7; Family ID=1158; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041129-P;20190723-EX00961-A003-IN0029-S00041129-N
SUBJECT_SAMPLE_FACTORS           	SU0036867	C-1NZJ4-S-00	Gender:Female | Condition:control	Age (years)=7.8; Family ID=1161; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041130-P;20190723-EX00961-A003-IN0029-S00041130-N
SUBJECT_SAMPLE_FACTORS           	SU0036868	C-1NZK2-S-00	Gender:Female | Condition:control	Age (years)=7.8; Family ID=1161; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041131-P;20190723-EX00961-A003-IN0029-S00041131-N
SUBJECT_SAMPLE_FACTORS           	SU0036869	C-1NZL0-S-00	Gender:Female | Condition:control	Age (years)=10.1; Family ID=1169; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041132-P;20190723-EX00961-A003-IN0029-S00041132-N
SUBJECT_SAMPLE_FACTORS           	SU0036870	C-1NZM8-S-00	Gender:Female | Condition:control	Age (years)=10.1; Family ID=1169; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041133-P;20190723-EX00961-A003-IN0029-S00041133-N
SUBJECT_SAMPLE_FACTORS           	SU0036871	C-1NZN5-S-00	Gender:Female | Condition:control	Age (years)=5.8; Family ID=1182; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041134-P;20190723-EX00961-A003-IN0029-S00041134-N
SUBJECT_SAMPLE_FACTORS           	SU0036872	C-1NZP1-S-00	Gender:Female | Condition:control	Age (years)=5.8; Family ID=1182; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041135-P;20190723-EX00961-A003-IN0029-S00041135-N
SUBJECT_SAMPLE_FACTORS           	SU0036873	C-1NZQ9-S-00	Gender:Male | Condition:control	Age (years)=11.7; Family ID=1185; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041136-P;20190723-EX00961-A003-IN0029-S00041136-N
SUBJECT_SAMPLE_FACTORS           	SU0036874	C-1NZR7-S-00	Gender:Male | Condition:control	Age (years)=11.7; Family ID=1185; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041137-P;20190723-EX00961-A003-IN0029-S00041137-N
SUBJECT_SAMPLE_FACTORS           	SU0036875	C-1NZS4-S-00	Gender:Female | Condition:control	Age (years)=5.5; Family ID=1188; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041138-P;20190723-EX00961-A003-IN0029-S00041138-N
SUBJECT_SAMPLE_FACTORS           	SU0036876	C-1NZT2-S-00	Gender:Female | Condition:control	Age (years)=5.5; Family ID=1188; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041139-P;20190723-EX00961-A003-IN0029-S00041139-N
SUBJECT_SAMPLE_FACTORS           	SU0036877	C-1NZU0-S-00	Gender:Male | Condition:control	Age (years)=11.9; Family ID=1193; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041140-P;20190723-EX00961-A003-IN0029-S00041140-N
SUBJECT_SAMPLE_FACTORS           	SU0036878	C-1NZV8-S-00	Gender:Male | Condition:control	Age (years)=11.9; Family ID=1193; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041141-P;20190723-EX00961-A003-IN0029-S00041141-N
SUBJECT_SAMPLE_FACTORS           	SU0036879	C-1NZW6-S-00	Gender:Male | Condition:control	Age (years)=7.7; Family ID=1200; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041142-P;20190723-EX00961-A003-IN0029-S00041142-N
SUBJECT_SAMPLE_FACTORS           	SU0036880	C-1NZX3-S-00	Gender:Male | Condition:control	Age (years)=7.7; Family ID=1200; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041143-P;20190723-EX00961-A003-IN0029-S00041143-N
SUBJECT_SAMPLE_FACTORS           	SU0036881	C-1NZY1-S-00	Gender:Male | Condition:asthmatic	Age (years)=12.8; Family ID=1205; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041144-P;20190723-EX00961-A003-IN0029-S00041144-N
SUBJECT_SAMPLE_FACTORS           	SU0036882	C-1P009-S-00	Gender:Male | Condition:asthmatic	Age (years)=12.8; Family ID=1205; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041145-P;20190723-EX00961-A003-IN0029-S00041145-N
SUBJECT_SAMPLE_FACTORS           	SU0036883	C-1P017-S-00	Gender:Female | Condition:control	Age (years)=8.4; Family ID=1217; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041146-P;20190723-EX00961-A003-IN0029-S00041146-N
SUBJECT_SAMPLE_FACTORS           	SU0036884	C-1P025-S-00	Gender:Female | Condition:control	Age (years)=8.4; Family ID=1217; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041147-P;20190723-EX00961-A003-IN0029-S00041147-N
SUBJECT_SAMPLE_FACTORS           	SU0036885	C-1P033-S-00	Gender:Male | Condition:control	Age (years)=7.9; Family ID=1218; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041148-P;20190723-EX00961-A003-IN0029-S00041148-N
SUBJECT_SAMPLE_FACTORS           	SU0036886	C-1P041-S-00	Gender:Male | Condition:control	Age (years)=7.9; Family ID=1218; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041149-P;20190723-EX00961-A003-IN0029-S00041149-N
SUBJECT_SAMPLE_FACTORS           	SU0036887	C-1P058-S-00	Gender:Male | Condition:control	Age (years)=7.8; Family ID=1220; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041150-P;20190723-EX00961-A003-IN0029-S00041150-N
SUBJECT_SAMPLE_FACTORS           	SU0036888	C-1P066-S-00	Gender:Male | Condition:control	Age (years)=7.8; Family ID=1220; Sample type=Sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-S00041151-P;20190723-EX00961-A003-IN0029-S00041151-N
SUBJECT_SAMPLE_FACTORS           	-	R00CHRPL1-1	Gender:CHEAR | Condition:CHEAR	Age (years)=CHEAR; Family ID=CHEAR; Sample type=CHEAR reference; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-R00CHRPL1-1-P;20190723-EX00961-A003-IN0029-R00CHRPL1-1-N
SUBJECT_SAMPLE_FACTORS           	-	R00CHRPL1-2	Gender:CHEAR | Condition:CHEAR	Age (years)=CHEAR; Family ID=CHEAR; Sample type=CHEAR reference; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-R00CHRPL1-2-P;20190723-EX00961-A003-IN0029-R00CHRPL1-2-N
SUBJECT_SAMPLE_FACTORS           	-	R00CHRPL1-3	Gender:CHEAR | Condition:CHEAR	Age (years)=CHEAR; Family ID=CHEAR; Sample type=CHEAR reference; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-R00CHRPL1-3-P;20190723-EX00961-A003-IN0029-R00CHRPL1-3-N
SUBJECT_SAMPLE_FACTORS           	-	R00CHRPL1-4	Gender:CHEAR | Condition:CHEAR	Age (years)=CHEAR; Family ID=CHEAR; Sample type=CHEAR reference; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-R00CHRPL1-4-P;20190723-EX00961-A003-IN0029-R00CHRPL1-4-N
SUBJECT_SAMPLE_FACTORS           	-	Master pool-01	Gender:POOL | Condition:POOL	Age (years)=POOL; Family ID=POOL; Sample type=Pooled sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-CS00000MP-01-P;20190723-EX00961-A003-IN0029-CS00000MP-01-N
SUBJECT_SAMPLE_FACTORS           	-	Master pool-02	Gender:POOL | Condition:POOL	Age (years)=POOL; Family ID=POOL; Sample type=Pooled sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-CS00000MP-02-P;20190723-EX00961-A003-IN0029-CS00000MP-02-N
SUBJECT_SAMPLE_FACTORS           	-	Master pool-03	Gender:POOL | Condition:POOL	Age (years)=POOL; Family ID=POOL; Sample type=Pooled sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-CS00000MP-03-P;20190723-EX00961-A003-IN0029-CS00000MP-03-N
SUBJECT_SAMPLE_FACTORS           	-	Master pool-04	Gender:POOL | Condition:POOL	Age (years)=POOL; Family ID=POOL; Sample type=Pooled sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-CS00000MP-04-P;20190723-EX00961-A003-IN0029-CS00000MP-04-N
SUBJECT_SAMPLE_FACTORS           	-	Master pool-05	Gender:POOL | Condition:POOL	Age (years)=POOL; Family ID=POOL; Sample type=Pooled sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-CS00000MP-05-P;20190723-EX00961-A003-IN0029-CS00000MP-05-N
SUBJECT_SAMPLE_FACTORS           	-	Master pool-06	Gender:POOL | Condition:POOL	Age (years)=POOL; Family ID=POOL; Sample type=Pooled sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-CS00000MP-06-P;20190723-EX00961-A003-IN0029-CS00000MP-06-N
SUBJECT_SAMPLE_FACTORS           	-	Master pool-07	Gender:POOL | Condition:POOL	Age (years)=POOL; Family ID=POOL; Sample type=Pooled sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-CS00000MP-07-P;20190723-EX00961-A003-IN0029-CS00000MP-07-N
SUBJECT_SAMPLE_FACTORS           	-	Master pool-08	Gender:POOL | Condition:POOL	Age (years)=POOL; Family ID=POOL; Sample type=Pooled sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-CS00000MP-08-P;20190723-EX00961-A003-IN0029-CS00000MP-08-N
SUBJECT_SAMPLE_FACTORS           	-	Master pool-09	Gender:POOL | Condition:POOL	Age (years)=POOL; Family ID=POOL; Sample type=Pooled sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-CS00000MP-09-P;20190723-EX00961-A003-IN0029-CS00000MP-09-N
SUBJECT_SAMPLE_FACTORS           	-	Master pool-10	Gender:POOL | Condition:POOL	Age (years)=POOL; Family ID=POOL; Sample type=Pooled sample; RAW_FILE_NAME=20190723-EX00961-A003-IN0029-CS00000MP-10-P;20190723-EX00961-A003-IN0029-CS00000MP-10-N
#COLLECTION
CO:COLLECTION_SUMMARY            	Standard blood serum collection protocol
CO:SAMPLE_TYPE                   	Blood (serum)
CO:STORAGE_CONDITIONS            	-80℃
#TREATMENT
TR:TREATMENT_SUMMARY             	This is observational study
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	Standard untargeted metabolomics sample preparation (see enclosed protocol)
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_SUMMARY        	RP-LCMS-Positive
CH:CHROMATOGRAPHY_TYPE           	Reversed phase
CH:INSTRUMENT_NAME               	Agilent 1290 Infinity II
CH:COLUMN_NAME                   	Waters Acquity BEH HSS T3 (100 x 2.1mm, 1.8um)
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:INSTRUMENT_NAME               	Agilent 6540 QTOF
MS:INSTRUMENT_TYPE               	QTOF
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	POSITIVE
MS:MS_COMMENTS                   	Untargeted recursive search (Agilent Qual/MPP/In-house software)
MS:MS_RESULTS_FILE               	ST001383_AN002304_Results.txt	UNITS:Peak area normalized	Has m/z:Yes	Has RT:Yes	RT units:Minutes
#END