#METABOLOMICS WORKBENCH NReisdorphLab_20210424_132817 DATATRACK_ID:2599 STUDY_ID:ST001750 ANALYSIS_ID:AN002853 PROJECT_ID:PR001122 VERSION 1 CREATED_ON April 27, 2021, 8:03 am #PROJECT PR:PROJECT_TITLE Gut microbiome influence on metabolic 1 disease in HIV and high-risk populations PR:PROJECT_SUMMARY Poor metabolic health, characterized by insulin resistance and dyslipidemia, is PR:PROJECT_SUMMARY higher in people living with HIV (PLWH) and has been linked with inflammation, PR:PROJECT_SUMMARY anti-retroviral therapy (ART) drugs, and ART-associated lipodystrophy (LD). PR:PROJECT_SUMMARY Metabolic disease is associated with gut microbiome composition outside the PR:PROJECT_SUMMARY context of HIV but has not been deeply explored in HIV infection nor in PR:PROJECT_SUMMARY high-risk men who have sex with men (HR-MSM), who have a highly altered gut PR:PROJECT_SUMMARY microbiome composition. Furthermore, the contribution of increased bacterial PR:PROJECT_SUMMARY translocation and associated systemic inflammation that has been described in PR:PROJECT_SUMMARY HIV-positive and HR-MSM individuals has not been explored. We used a multi-omic PR:PROJECT_SUMMARY approach to explore relationships between gut microbes, immune phenotypes, diet, PR:PROJECT_SUMMARY and metabolic health across ART-treated PLWH with and without .D untreated PR:PROJECT_SUMMARY PLWH; and HR-MSM. For PLWH on ART, we further explored associations with the PR:PROJECT_SUMMARY plasma metabolome. PR:INSTITUTE University of Colorado Anschutz Medical Campus PR:LAST_NAME Reisdorph PR:FIRST_NAME Nichole PR:ADDRESS 12850 East Montview Blvd, Aurora, CO, 80045, USA PR:EMAIL nichole.reisdorph@cuanschutz.edu PR:PHONE 303-724-9234 #STUDY ST:STUDY_TITLE Gut microbiome influence on metabolic 1 disease in HIV and high-risk populations ST:STUDY_SUMMARY Poor metabolic health, characterized by insulin resistance and dyslipidemia, is ST:STUDY_SUMMARY higher in people living with HIV (PLWH) and has been linked with inflammation, ST:STUDY_SUMMARY anti-retroviral therapy (ART) drugs, and ART-associated lipodystrophy (LD). ST:STUDY_SUMMARY Metabolic disease is associated with gut microbiome composition outside the ST:STUDY_SUMMARY context of HIV but has not been deeply explored in HIV infection nor in ST:STUDY_SUMMARY high-risk men who have sex with men (HR-MSM), who have a highly altered gut ST:STUDY_SUMMARY microbiome composition. Furthermore, the contribution of increased bacterial ST:STUDY_SUMMARY translocation and associated systemic inflammation that has been described in ST:STUDY_SUMMARY HIV-positive and HR-MSM individuals has not been explored. We used a multi-omic ST:STUDY_SUMMARY approach to explore relationships between gut microbes, immune phenotypes, diet, ST:STUDY_SUMMARY and metabolic health across ART-treated PLWH with and without .D untreated ST:STUDY_SUMMARY PLWH; and HR-MSM. For PLWH on ART, we further explored associations with the ST:STUDY_SUMMARY plasma metabolome. ST:INSTITUTE University of Colorado Anschutz Medical Campus ST:LAST_NAME Reisdorph ST:FIRST_NAME Nichole ST:ADDRESS 12850 East Montview Blvd, Aurora, CO, 80045, USA ST:EMAIL nichole.reisdorph@cuanschutz.edu ST:PHONE 303-724-9234 #SUBJECT SU:SUBJECT_TYPE Mammal SU:SUBJECT_SPECIES Homo sapiens SU:TAXONOMY_ID 9606 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data SUBJECT_SAMPLE_FACTORS GLD009 9 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=9; Age=46; Gender=Male; Race=Black/African American; Hispanic=No; Height=176; Weight=82.2; BMI=26.5; Adiponectin=3.8; Glucose=71; HDL=29; Insulin=9; LDL=83; Leptin=9.8; Triglycerides=82; Fasting=Yes; CD4_CD38_single_positive_cells=66; CD4_count=819; CD4_HLADR_single_positive_cells=2; CD4_percent=27; CD4_HLADR_CD38_percent=6; CD8_CD38_single_positive_cells=13; CD8_count=1335; CD8_HLADR_single_positive_cells=20; CD8_percent=44; CD8_HLADR_CD38_percent=8; Lymphocyte_count=3034; Lymphocyte_percent=39.4 SUBJECT_SAMPLE_FACTORS GLD019 19 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=19; Age=47; Gender=Male; Race=Black/African American; Hispanic=No; Height=186; Weight=80; BMI=23.1; Adiponectin=28.1; Glucose=80; HDL=55; Insulin=3; LDL=110; Leptin=2.9; Triglycerides=78; Fasting=Yes; CD4_CD38_single_positive_cells=63; CD4_count=177; CD4_HLADR_single_positive_cells=3; CD4_percent=19; CD4_HLADR_CD38_percent=5; CD8_CD38_single_positive_cells=26; CD8_count=503; CD8_HLADR_single_positive_cells=9; CD8_percent=54; CD8_HLADR_CD38_percent=10; Lymphocyte_count=931; Lymphocyte_percent=17.9 SUBJECT_SAMPLE_FACTORS GLD020 20 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=20; Age=54; Gender=Male; Race=White; Hispanic=No; Height=172; Weight=74.9; BMI=25.3; Adiponectin=2.7; Glucose=93; HDL=41; Insulin=3; LDL=126; Leptin=2.2; Triglycerides=66; Fasting=Yes; CD4_CD38_single_positive_cells=76; CD4_count=1200; CD4_HLADR_single_positive_cells=1; CD4_percent=35; CD4_HLADR_CD38_percent=1; CD8_CD38_single_positive_cells=11; CD8_count=1166; CD8_HLADR_single_positive_cells=2; CD8_percent=34; CD8_HLADR_CD38_percent=2; Lymphocyte_count=3429; Lymphocyte_percent=43.4 SUBJECT_SAMPLE_FACTORS GLD021 21 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=21; Age=58; Gender=Male; Race=White; Hispanic=No; Height=166; Weight=67.5; BMI=24.5; Adiponectin=12.9; Glucose=87; HDL=40; Insulin=3; LDL=152; Leptin=3; Triglycerides=206; Fasting=Yes; CD4_CD38_single_positive_cells=71; CD4_count=578; CD4_HLADR_single_positive_cells=1; CD4_percent=33; CD4_HLADR_CD38_percent=3; CD8_CD38_single_positive_cells=23; CD8_count=910; CD8_HLADR_single_positive_cells=11; CD8_percent=52; CD8_HLADR_CD38_percent=8; Lymphocyte_count=1750; Lymphocyte_percent=40.7 SUBJECT_SAMPLE_FACTORS GLD022 22 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=22; Age=55; Gender=Male; Race=White; Hispanic=Yes; Height=173; Weight=82; BMI=27.4; Adiponectin=7.7; Glucose=77; HDL=47; Insulin=11; LDL=80; Leptin=9.6; Triglycerides=153; Fasting=Yes; CD4_CD38_single_positive_cells=73; CD4_count=545; CD4_HLADR_single_positive_cells=2; CD4_percent=19; CD4_HLADR_CD38_percent=5; CD8_CD38_single_positive_cells=36; CD8_count=1399; CD8_HLADR_single_positive_cells=14; CD8_percent=49; CD8_HLADR_CD38_percent=8; Lymphocyte_count=2855; Lymphocyte_percent=30.7 SUBJECT_SAMPLE_FACTORS GLD023 23 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=23; Age=49; Gender=Male; Race=White; Hispanic=No; Height=177; Weight=71.2; BMI=22.7; Adiponectin=17.8; Glucose=87; HDL=60; Insulin=9; LDL=99; Leptin=3.7; Triglycerides=89; Fasting=Yes; CD4_CD38_single_positive_cells=74; CD4_count=510; CD4_HLADR_single_positive_cells=1; CD4_percent=35; CD4_HLADR_CD38_percent=3; CD8_CD38_single_positive_cells=30; CD8_count=568; CD8_HLADR_single_positive_cells=12; CD8_percent=39; CD8_HLADR_CD38_percent=12; Lymphocyte_count=1456; Lymphocyte_percent=36.4 SUBJECT_SAMPLE_FACTORS GLD025 25 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=25; Age=67; Gender=Male; Race=White; Hispanic=No; Height=175; Weight=90.9; BMI=29.7; Adiponectin=73; Glucose=121; HDL=51; Insulin=9; LDL=107; Leptin=13.9; Triglycerides=127; Fasting=Yes; CD4_CD38_single_positive_cells=45; CD4_count=622; CD4_HLADR_single_positive_cells=2; CD4_percent=26; CD4_HLADR_CD38_percent=5; CD8_CD38_single_positive_cells=12; CD8_count=1339; CD8_HLADR_single_positive_cells=20; CD8_percent=56; CD8_HLADR_CD38_percent=7; Lymphocyte_count=2391.9; Lymphocyte_percent=46.9 SUBJECT_SAMPLE_FACTORS GLD026 26 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=26; Age=53; Gender=Male; Race=Black/African American; Hispanic=No; Height=181; Weight=88; BMI=26.9; Adiponectin=2.4; Glucose=98; HDL=43; Insulin=13; LDL=107; Leptin=3.3; Triglycerides=128; Fasting=Yes; CD4_CD38_single_positive_cells=31; CD4_count=838; CD4_HLADR_single_positive_cells=3; CD4_percent=35; CD4_HLADR_CD38_percent=2; CD8_CD38_single_positive_cells=4; CD8_count=838; CD8_HLADR_single_positive_cells=8; CD8_percent=35; CD8_HLADR_CD38_percent=6; Lymphocyte_count=2394; Lymphocyte_percent=35.2 SUBJECT_SAMPLE_FACTORS GLD027 27 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=27; Age=50; Gender=Male; Race=White; Hispanic=No; Height=179; Weight=93; BMI=29; Adiponectin=3.7; Glucose=90; HDL=35; Insulin=5; LDL=85; Leptin=5.4; Triglycerides=584; Fasting=Yes; CD4_CD38_single_positive_cells=42; CD4_count=648; CD4_HLADR_single_positive_cells=2; CD4_percent=39; CD4_HLADR_CD38_percent=2; CD8_CD38_single_positive_cells=11; CD8_count=615; CD8_HLADR_single_positive_cells=12; CD8_percent=37; CD8_HLADR_CD38_percent=5; Lymphocyte_count=1661.6; Lymphocyte_percent=26.8 SUBJECT_SAMPLE_FACTORS GLD029 29 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=29; Age=44; Gender=Male; Race=White; Hispanic=No; Height=183; Weight=96.9; BMI=28.9; Adiponectin=7; Glucose=95; HDL=43; Insulin=6; LDL=99; Leptin=11.9; Triglycerides=93; Fasting=Yes; CD4_CD38_single_positive_cells=1; CD4_count=1114; CD4_HLADR_single_positive_cells=1; CD4_percent=52; CD4_HLADR_CD38_percent=52; CD8_CD38_single_positive_cells=12; CD8_count=857; CD8_HLADR_single_positive_cells=7; CD8_percent=40; CD8_HLADR_CD38_percent=9; Lymphocyte_count=2142; Lymphocyte_percent=34 SUBJECT_SAMPLE_FACTORS GLD030 30 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=30; Age=37; Gender=Male; Race=White; Hispanic=Yes; Height=167; Weight=71.9; BMI=25.8; Adiponectin=1.7; Glucose=93; HDL=43; Insulin=5; LDL=128; Leptin=10.4; Triglycerides=97; Fasting=Yes; CD4_CD38_single_positive_cells=57; CD4_count=998; CD4_HLADR_single_positive_cells=2; CD4_percent=44; CD4_HLADR_CD38_percent=2; CD8_CD38_single_positive_cells=10; CD8_count=885; CD8_HLADR_single_positive_cells=8; CD8_percent=39; CD8_HLADR_CD38_percent=11; Lymphocyte_count=2269; Lymphocyte_percent=34.9 SUBJECT_SAMPLE_FACTORS GLD036 36 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=36; Age=46; Gender=Male; Race=White; Hispanic=No; Height=182; Weight=66.7; BMI=20.1; Adiponectin=8.8; Glucose=87; HDL=54; Insulin=3; LDL=79; Leptin=0.7; Triglycerides=61; Fasting=Yes; CD4_CD38_single_positive_cells=81; CD4_count=334; CD4_HLADR_single_positive_cells=2; CD4_percent=22; CD4_HLADR_CD38_percent=4; CD8_CD38_single_positive_cells=52; CD8_count=713; CD8_HLADR_single_positive_cells=6; CD8_percent=47; CD8_HLADR_CD38_percent=9; Lymphocyte_count=1516.2; Lymphocyte_percent=39.9 SUBJECT_SAMPLE_FACTORS GLD037 37 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=37; Age=57; Gender=Male; Race=White; Hispanic=No; Height=195; Weight=89.9; BMI=23.6; Adiponectin=4.1; Glucose=105; HDL=43; Insulin=8; LDL=97; Leptin=5; Triglycerides=96; Fasting=Yes; CD4_CD38_single_positive_cells=60; CD4_count=659; CD4_HLADR_single_positive_cells=2; CD4_percent=24; CD4_HLADR_CD38_percent=2; CD8_CD38_single_positive_cells=23; CD8_count=871; CD8_HLADR_single_positive_cells=3; CD8_percent=37; CD8_HLADR_CD38_percent=3; Lymphocyte_count=2353; Lymphocyte_percent=36.2 SUBJECT_SAMPLE_FACTORS GLD040 40 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=40; Age=45; Gender=Male; Race=Black/African American; Hispanic=No; Height=153; Weight=56; BMI=23.9; Adiponectin=14.4; Glucose=98; HDL=29; Insulin=10; LDL=86; Leptin=1.9; Triglycerides=57; Fasting=Yes; CD4_CD38_single_positive_cells=63; CD4_count=431; CD4_HLADR_single_positive_cells=3; CD4_percent=12; CD4_HLADR_CD38_percent=12; CD8_CD38_single_positive_cells=81; CD8_count=2084; CD8_HLADR_single_positive_cells=-; CD8_percent=58; CD8_HLADR_CD38_percent=14; Lymphocyte_count=3593.1; Lymphocyte_percent=41.3 SUBJECT_SAMPLE_FACTORS GLD045 45 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=45; Age=51; Gender=Male; Race=White; Hispanic=No; Height=178; Weight=83.2; BMI=26.3; Adiponectin=4.3; Glucose=103; HDL=36; Insulin=19; LDL=74; Leptin=11.6; Triglycerides=67; Fasting=Yes; CD4_CD38_single_positive_cells=62; CD4_count=908; CD4_HLADR_single_positive_cells=1; CD4_percent=25; CD4_HLADR_CD38_percent=3; CD8_CD38_single_positive_cells=61; CD8_count=1743; CD8_HLADR_single_positive_cells=-; CD8_percent=48; CD8_HLADR_CD38_percent=19; Lymphocyte_count=3631.2; Lymphocyte_percent=35.6 SUBJECT_SAMPLE_FACTORS GLD055 55 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=55; Age=48; Gender=Male; Race=White; Hispanic=No; Height=179; Weight=86.6; BMI=27; Adiponectin=4.7; Glucose=89; HDL=37; Insulin=14; LDL=145; Leptin=21.9; Triglycerides=178; Fasting=Yes; CD4_CD38_single_positive_cells=51; CD4_count=550; CD4_HLADR_single_positive_cells=1; CD4_percent=17; CD4_HLADR_CD38_percent=4; CD8_CD38_single_positive_cells=5; CD8_count=2007; CD8_HLADR_single_positive_cells=1; CD8_percent=62; CD8_HLADR_CD38_percent=12; Lymphocyte_count=3237; Lymphocyte_percent=49.8 SUBJECT_SAMPLE_FACTORS GLD057 57 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=57; Age=58; Gender=Male; Race=White; Hispanic=No; Height=176; Weight=72.5; BMI=23.4; Adiponectin=11.4; Glucose=116; HDL=59; Insulin=32; LDL=97; Leptin=4.2; Triglycerides=178; Fasting=Yes; CD4_CD38_single_positive_cells=83; CD4_count=240; CD4_HLADR_single_positive_cells=1; CD4_percent=26; CD4_HLADR_CD38_percent=4; CD8_CD38_single_positive_cells=44; CD8_count=314; CD8_HLADR_single_positive_cells=5; CD8_percent=34; CD8_HLADR_CD38_percent=12; Lymphocyte_count=924; Lymphocyte_percent=14 SUBJECT_SAMPLE_FACTORS GLD069 69 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=69; Age=49; Gender=Male; Race=Black/African American; Hispanic=No; Height=188; Weight=102; BMI=28.9; Adiponectin=4.5; Glucose=109; HDL=44; Insulin=4; LDL=102; Leptin=3.5; Triglycerides=74; Fasting=Yes; CD4_CD38_single_positive_cells=70; CD4_count=1149.98; CD4_HLADR_single_positive_cells=1; CD4_percent=48; CD4_HLADR_CD38_percent=2; CD8_CD38_single_positive_cells=28; CD8_count=742.7; CD8_HLADR_single_positive_cells=3; CD8_percent=31; CD8_HLADR_CD38_percent=4; Lymphocyte_count=2395.8; Lymphocyte_percent=36.3 SUBJECT_SAMPLE_FACTORS GLD072 72 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=72; Age=62; Gender=Male; Race=White; Hispanic=No; Height=176; Weight=62.6; BMI=20.2; Adiponectin=5.1; Glucose=94; HDL=52; Insulin=3; LDL=44; Leptin=2.3; Triglycerides=146; Fasting=Yes; CD4_CD38_single_positive_cells=85; CD4_count=686.91; CD4_HLADR_single_positive_cells=-; CD4_percent=57; CD4_HLADR_CD38_percent=1; CD8_CD38_single_positive_cells=23; CD8_count=361.53; CD8_HLADR_single_positive_cells=3; CD8_percent=30; CD8_HLADR_CD38_percent=9; Lymphocyte_count=1205.1; Lymphocyte_percent=30.9 SUBJECT_SAMPLE_FACTORS GLD079 79 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=79; Age=63; Gender=Male; Race=White; Hispanic=No; Height=177.8; Weight=72.8; BMI=23; Adiponectin=1.7; Glucose=97; HDL=26; Insulin=10; LDL=86; Leptin=2.8; Triglycerides=172; Fasting=Yes; CD4_CD38_single_positive_cells=32; CD4_count=190; CD4_HLADR_single_positive_cells=2; CD4_percent=17; CD4_HLADR_CD38_percent=5; CD8_CD38_single_positive_cells=20; CD8_count=358; CD8_HLADR_single_positive_cells=3; CD8_percent=32; CD8_HLADR_CD38_percent=16; Lymphocyte_count=1120; Lymphocyte_percent=16 SUBJECT_SAMPLE_FACTORS GLD080 80 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=80; Age=43; Gender=Male; Race=White; Hispanic=No; Height=172.7; Weight=83.5; BMI=28; Adiponectin=3.4; Glucose=89; HDL=38; Insulin=5; LDL=100; Leptin=5.1; Triglycerides=103; Fasting=Yes; CD4_CD38_single_positive_cells=45; CD4_count=922.32; CD4_HLADR_single_positive_cells=2; CD4_percent=28; CD4_HLADR_CD38_percent=5; CD8_CD38_single_positive_cells=41; CD8_count=1976.4; CD8_HLADR_single_positive_cells=10; CD8_percent=60; CD8_HLADR_CD38_percent=16; Lymphocyte_count=3294; Lymphocyte_percent=54 SUBJECT_SAMPLE_FACTORS GLD104 104 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=104; Age=62; Gender=Male; Race=White; Hispanic=No; Height=167; Weight=74.3; BMI=26.6; Adiponectin=3.4; Glucose=121; HDL=38; Insulin=13; LDL=91; Leptin=4.6; Triglycerides=97; Fasting=Yes; CD4_CD38_single_positive_cells=68; CD4_count=1237; CD4_HLADR_single_positive_cells=-; CD4_percent=52; CD4_HLADR_CD38_percent=1; CD8_CD38_single_positive_cells=44; CD8_count=666; CD8_HLADR_single_positive_cells=-; CD8_percent=28; CD8_HLADR_CD38_percent=4; Lymphocyte_count=2378.8; Lymphocyte_percent=31.3 SUBJECT_SAMPLE_FACTORS GLD106 106 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=106; Age=57; Gender=Male; Race=White; Hispanic=No; Height=183.5; Weight=80.1; BMI=23.8; Adiponectin=5.6; Glucose=89; HDL=50; Insulin=2; LDL=81; Leptin=1.9; Triglycerides=77; Fasting=Yes; CD4_CD38_single_positive_cells=11; CD4_count=599; CD4_HLADR_single_positive_cells=2; CD4_percent=26; CD4_HLADR_CD38_percent=3; CD8_CD38_single_positive_cells=12; CD8_count=1360; CD8_HLADR_single_positive_cells=6; CD8_percent=59; CD8_HLADR_CD38_percent=3; Lymphocyte_count=2305; Lymphocyte_percent=46.1 SUBJECT_SAMPLE_FACTORS GLD112 112 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=112; Age=63; Gender=Male; Race=White; Hispanic=No; Height=184; Weight=87.3; BMI=25.8; Adiponectin=4; Glucose=95; HDL=51; Insulin=6; LDL=73; Leptin=6.3; Triglycerides=51; Fasting=Yes; CD4_CD38_single_positive_cells=62; CD4_count=385; CD4_HLADR_single_positive_cells=2; CD4_percent=33; CD4_HLADR_CD38_percent=3; CD8_CD38_single_positive_cells=45; CD8_count=385; CD8_HLADR_single_positive_cells=2; CD8_percent=33; CD8_HLADR_CD38_percent=6; Lymphocyte_count=1165.8; Lymphocyte_percent=18.5 SUBJECT_SAMPLE_FACTORS GLD119 119 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=119; Age=64; Gender=Male; Race=White; Hispanic=No; Height=179; Weight=90; BMI=28.1; Adiponectin=4.7; Glucose=130; HDL=35; Insulin=112; LDL=137; Leptin=4.4; Triglycerides=220; Fasting=Yes; CD4_CD38_single_positive_cells=61; CD4_count=566; CD4_HLADR_single_positive_cells=10; CD4_percent=24; CD4_HLADR_CD38_percent=9; CD8_CD38_single_positive_cells=10; CD8_count=944; CD8_HLADR_single_positive_cells=14; CD8_percent=40; CD8_HLADR_CD38_percent=7; Lymphocyte_count=2359.8; Lymphocyte_percent=43.7 SUBJECT_SAMPLE_FACTORS GLD128 128 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=128; Age=42; Gender=Male; Race=-; Hispanic=No; Height=188; Weight=165; BMI=21.2; Adiponectin=10.2; Glucose=97; HDL=76; Insulin=3; LDL=89; Leptin=3.6; Triglycerides=127; Fasting=Yes; CD4_CD38_single_positive_cells=59; CD4_count=594; CD4_HLADR_single_positive_cells=2; CD4_percent=37; CD4_HLADR_CD38_percent=3; CD8_CD38_single_positive_cells=20; CD8_count=546; CD8_HLADR_single_positive_cells=3; CD8_percent=34; CD8_HLADR_CD38_percent=4; Lymphocyte_count=1606; Lymphocyte_percent=30.3 SUBJECT_SAMPLE_FACTORS GLD130 130 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=130; Age=65; Gender=Male; Race=White; Hispanic=No; Height=174; Weight=73.5; BMI=24.3; Adiponectin=3.2; Glucose=110; HDL=29; Insulin=30; LDL=80; Leptin=10; Triglycerides=189; Fasting=Yes; CD4_CD38_single_positive_cells=68; CD4_count=802; CD4_HLADR_single_positive_cells=4; CD4_percent=27; CD4_HLADR_CD38_percent=6; CD8_CD38_single_positive_cells=31; CD8_count=1603; CD8_HLADR_single_positive_cells=6; CD8_percent=54; CD8_HLADR_CD38_percent=10; Lymphocyte_count=2968.4; Lymphocyte_percent=36.2 SUBJECT_SAMPLE_FACTORS GLD131 131 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=131; Age=54; Gender=Male; Race=White; Hispanic=No; Height=172; Weight=87; BMI=29.4; Adiponectin=3.5; Glucose=105; HDL=36; Insulin=16; LDL=105; Leptin=23.9; Triglycerides=199; Fasting=Yes; CD4_CD38_single_positive_cells=56; CD4_count=692; CD4_HLADR_single_positive_cells=1; CD4_percent=48; CD4_HLADR_CD38_percent=5; CD8_CD38_single_positive_cells=20; CD8_count=274; CD8_HLADR_single_positive_cells=6; CD8_percent=19; CD8_HLADR_CD38_percent=8; Lymphocyte_count=1441.6; Lymphocyte_percent=27.2 SUBJECT_SAMPLE_FACTORS GLD132 132 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=132; Age=63; Gender=Male; Race=White; Hispanic=No; Height=182.9; Weight=74.4; BMI=22.3; Adiponectin=8; Glucose=105; HDL=24; Insulin=8; LDL=51; Leptin=4.8; Triglycerides=79; Fasting=Yes; CD4_CD38_single_positive_cells=62; CD4_count=955; CD4_HLADR_single_positive_cells=-; CD4_percent=39; CD4_HLADR_CD38_percent=1; CD8_CD38_single_positive_cells=21; CD8_count=808; CD8_HLADR_single_positive_cells=7; CD8_percent=33; CD8_HLADR_CD38_percent=5; Lymphocyte_count=2448; Lymphocyte_percent=15.3 SUBJECT_SAMPLE_FACTORS GLD133 133 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=133; Age=61; Gender=Male; Race=White; Hispanic=No; Height=182; Weight=92.9; BMI=28; Adiponectin=4.5; Glucose=77; HDL=18; Insulin=17; LDL=64; Leptin=17.6; Triglycerides=197; Fasting=Yes; CD4_CD38_single_positive_cells=58; CD4_count=1013; CD4_HLADR_single_positive_cells=1; CD4_percent=22; CD4_HLADR_CD38_percent=5; CD8_CD38_single_positive_cells=38; CD8_count=2441; CD8_HLADR_single_positive_cells=1; CD8_percent=53; CD8_HLADR_CD38_percent=5; Lymphocyte_count=4605.7; Lymphocyte_percent=58.3 SUBJECT_SAMPLE_FACTORS GLD145 145 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=145; Age=64; Gender=Male; Race=White; Hispanic=No; Height=173; Weight=66.5; BMI=22.3; Adiponectin=3.2; Glucose=99; HDL=26; Insulin=23; LDL=53; Leptin=5.5; Triglycerides=321; Fasting=Yes; CD4_CD38_single_positive_cells=54; CD4_count=562; CD4_HLADR_single_positive_cells=1; CD4_percent=36; CD4_HLADR_CD38_percent=4; CD8_CD38_single_positive_cells=8; CD8_count=578; CD8_HLADR_single_positive_cells=8; CD8_percent=37; CD8_HLADR_CD38_percent=5; Lymphocyte_count=1561; Lymphocyte_percent=22.3 SUBJECT_SAMPLE_FACTORS GLD146 146 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=146; Age=65; Gender=Male; Race=White; Hispanic=No; Height=184; Weight=87.3; BMI=25.8; Adiponectin=9.4; Glucose=85; HDL=63; Insulin=6; LDL=101; Leptin=15.9; Triglycerides=74; Fasting=Yes; CD4_CD38_single_positive_cells=60; CD4_count=678; CD4_HLADR_single_positive_cells=2; CD4_percent=32; CD4_HLADR_CD38_percent=5; CD8_CD38_single_positive_cells=13; CD8_count=720; CD8_HLADR_single_positive_cells=1; CD8_percent=34; CD8_HLADR_CD38_percent=5; Lymphocyte_count=2118.4; Lymphocyte_percent=33.1 SUBJECT_SAMPLE_FACTORS GLD152 152 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=152; Age=55; Gender=Male; Race=White; Hispanic=Yes; Height=177; Weight=75.5; BMI=24.1; Adiponectin=7.8; Glucose=92; HDL=34; Insulin=3; LDL=81; Leptin=6.5; Triglycerides=256; Fasting=Yes; CD4_CD38_single_positive_cells=72; CD4_count=311; CD4_HLADR_single_positive_cells=1; CD4_percent=15; CD4_HLADR_CD38_percent=4; CD8_CD38_single_positive_cells=59; CD8_count=1120; CD8_HLADR_single_positive_cells=1; CD8_percent=54; CD8_HLADR_CD38_percent=5; Lymphocyte_count=2073.6; Lymphocyte_percent=43.2 SUBJECT_SAMPLE_FACTORS GLD156 156 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=156; Age=67; Gender=Male; Race=White; Hispanic=No; Height=170; Weight=57.9; BMI=20; Adiponectin=3; Glucose=101; HDL=25; Insulin=6; LDL=36; Leptin=3.4; Triglycerides=187; Fasting=Yes; CD4_CD38_single_positive_cells=52; CD4_count=359; CD4_HLADR_single_positive_cells=1; CD4_percent=30; CD4_HLADR_CD38_percent=3; CD8_CD38_single_positive_cells=77; CD8_count=779; CD8_HLADR_single_positive_cells=-; CD8_percent=65; CD8_HLADR_CD38_percent=13; Lymphocyte_count=1197; Lymphocyte_percent=9 SUBJECT_SAMPLE_FACTORS GLD157 157 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=157; Age=66; Gender=Male; Race=White; Hispanic=No; Height=180; Weight=71; BMI=21.9; Adiponectin=20.1; Glucose=110; HDL=49; Insulin=4; LDL=101; Leptin=5.4; Triglycerides=84; Fasting=Yes; CD4_CD38_single_positive_cells=38; CD4_count=455; CD4_HLADR_single_positive_cells=3; CD4_percent=24; CD4_HLADR_CD38_percent=4; CD8_CD38_single_positive_cells=10; CD8_count=1156; CD8_HLADR_single_positive_cells=4; CD8_percent=61; CD8_HLADR_CD38_percent=2; Lymphocyte_count=1895; Lymphocyte_percent=37.9 SUBJECT_SAMPLE_FACTORS GLD166 166 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=166; Age=59; Gender=Male; Race=White; Hispanic=No; Height=183; Weight=98; BMI=29.3; Adiponectin=3.6; Glucose=80; HDL=44; Insulin=4; LDL=54; Leptin=5.7; Triglycerides=169; Fasting=Yes; CD4_CD38_single_positive_cells=33; CD4_count=557; CD4_HLADR_single_positive_cells=8; CD4_percent=31; CD4_HLADR_CD38_percent=8; CD8_CD38_single_positive_cells=5; CD8_count=1025; CD8_HLADR_single_positive_cells=26; CD8_percent=57; CD8_HLADR_CD38_percent=5; Lymphocyte_count=1798; Lymphocyte_percent=29 SUBJECT_SAMPLE_FACTORS GLD167 167 Sample_Type:Human | Lipodystrophy:YES | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=167; Age=48; Gender=Male; Race=Black/African American; Hispanic=No; Height=169; Weight=55.3; BMI=19.8; Adiponectin=13.7; Glucose=58; HDL=40; Insulin=5; LDL=72; Leptin=7; Triglycerides=69; Fasting=Yes; CD4_CD38_single_positive_cells=27; CD4_count=104; CD4_HLADR_single_positive_cells=16; CD4_percent=14; CD4_HLADR_CD38_percent=24; CD8_CD38_single_positive_cells=18; CD8_count=467; CD8_HLADR_single_positive_cells=17; CD8_percent=63; CD8_HLADR_CD38_percent=17; Lymphocyte_count=742.4; Lymphocyte_percent=25.6 SUBJECT_SAMPLE_FACTORS DM002 DM002 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=DM002; Age=30; Gender=Male; Race=White; Hispanic=No; Height=186; Weight=72.4; BMI=21; Adiponectin=4.4; Glucose=93; HDL=34; Insulin=6; LDL=60; Leptin=6.8; Triglycerides=110; Fasting=Yes; CD4_CD38_single_positive_cells=59; CD4_count=573.21; CD4_HLADR_single_positive_cells=2; CD4_percent=27; CD4_HLADR_CD38_percent=2; CD8_CD38_single_positive_cells=11; CD8_count=849.2; CD8_HLADR_single_positive_cells=5; CD8_percent=40; CD8_HLADR_CD38_percent=5; Lymphocyte_count=2123; Lymphocyte_percent=38.6 SUBJECT_SAMPLE_FACTORS DM003 DM003 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=DM003; Age=31; Gender=Male; Race=White; Hispanic=No; Height=-; Weight=-; BMI=-; Adiponectin=3.4; Glucose=88; HDL=34; Insulin=3; LDL=81; Leptin=2.7; Triglycerides=81; Fasting=Yes; CD4_CD38_single_positive_cells=64; CD4_count=486; CD4_HLADR_single_positive_cells=-; CD4_percent=28; CD4_HLADR_CD38_percent=1; CD8_CD38_single_positive_cells=27; CD8_count=746; CD8_HLADR_single_positive_cells=-; CD8_percent=43; CD8_HLADR_CD38_percent=2; Lymphocyte_count=1734.6; Lymphocyte_percent=41.3 SUBJECT_SAMPLE_FACTORS DM019 DM19 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=DM19; Age=35; Gender=Male; Race=White; Hispanic=No; Height=177; Weight=71.6; BMI=22.9; Adiponectin=6.1; Glucose=98; HDL=45; Insulin=7; LDL=128; Leptin=6.2; Triglycerides=119; Fasting=Yes; CD4_CD38_single_positive_cells=72; CD4_count=1014; CD4_HLADR_single_positive_cells=2; CD4_percent=50; CD4_HLADR_CD38_percent=6; CD8_CD38_single_positive_cells=35; CD8_count=466; CD8_HLADR_single_positive_cells=5; CD8_percent=23; CD8_HLADR_CD38_percent=8; Lymphocyte_count=2027.2; Lymphocyte_percent=36.2 SUBJECT_SAMPLE_FACTORS DM032 DM032 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=DM032; Age=46; Gender=Male; Race=White; Hispanic=No; Height=170; Weight=62.7; BMI=21.7; Adiponectin=3.5; Glucose=91; HDL=37; Insulin=3; LDL=86; Leptin=2.3; Triglycerides=122; Fasting=Yes; CD4_CD38_single_positive_cells=91; CD4_count=1216; CD4_HLADR_single_positive_cells=-; CD4_percent=57; CD4_HLADR_CD38_percent=4; CD8_CD38_single_positive_cells=45; CD8_count=555; CD8_HLADR_single_positive_cells=5; CD8_percent=26; CD8_HLADR_CD38_percent=15; Lymphocyte_count=2133.6; Lymphocyte_percent=38.1 SUBJECT_SAMPLE_FACTORS DM034 DM034 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=DM034; Age=52; Gender=Male; Race=White; Hispanic=No; Height=177; Weight=70.5; BMI=22.5; Adiponectin=11.4; Glucose=92; HDL=55; Insulin=4; LDL=94; Leptin=5.4; Triglycerides=93; Fasting=Yes; CD4_CD38_single_positive_cells=79; CD4_count=753; CD4_HLADR_single_positive_cells=1; CD4_percent=47; CD4_HLADR_CD38_percent=3; CD8_CD38_single_positive_cells=42; CD8_count=753; CD8_HLADR_single_positive_cells=3; CD8_percent=47; CD8_HLADR_CD38_percent=7; Lymphocyte_count=1601.6; Lymphocyte_percent=36.4 SUBJECT_SAMPLE_FACTORS DM036 DM036 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=DM036; Age=46; Gender=Male; Race=White; Hispanic=No; Height=184; Weight=99; BMI=29.2; Adiponectin=5.3; Glucose=92; HDL=43; Insulin=11; LDL=113; Leptin=50.3; Triglycerides=202; Fasting=Yes; CD4_CD38_single_positive_cells=56; CD4_count=1361; CD4_HLADR_single_positive_cells=1; CD4_percent=48; CD4_HLADR_CD38_percent=1; CD8_CD38_single_positive_cells=15; CD8_count=1219; CD8_HLADR_single_positive_cells=5; CD8_percent=43; CD8_HLADR_CD38_percent=3; Lymphocyte_count=2835; Lymphocyte_percent=40.5 SUBJECT_SAMPLE_FACTORS DM052 DM052 Sample_Type:Human | Lipodystrophy:NO | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=DM052; Age=43; Gender=Male; Race=Black/African American; Hispanic=No; Height=172; Weight=70.9; BMI=24; Adiponectin=7.7; Glucose=80; HDL=33; Insulin=9; LDL=42; Leptin=5.1; Triglycerides=52; Fasting=Yes; CD4_CD38_single_positive_cells=52; CD4_count=331; CD4_HLADR_single_positive_cells=2; CD4_percent=22; CD4_HLADR_CD38_percent=4; CD8_CD38_single_positive_cells=35; CD8_count=406; CD8_HLADR_single_positive_cells=5; CD8_percent=27; CD8_HLADR_CD38_percent=7; Lymphocyte_count=1505; Lymphocyte_percent=35 SUBJECT_SAMPLE_FACTORS 113-W 2_mouse Sample_Type:Humanized mouse | Lipodystrophy:- | HIV_status:Negative | Antiviral_Treatment:No RAW_FILE_NAME=2_mouse; Age=-; Gender=-; Race=-; Hispanic=-; Height=-; Weight=-; BMI=-; Adiponectin=-; Glucose=-; HDL=-; Insulin=-; LDL=-; Leptin=-; Triglycerides=-; Fasting=-; CD4_CD38_single_positive_cells=-; CD4_count=-; CD4_HLADR_single_positive_cells=-; CD4_percent=-; CD4_HLADR_CD38_percent=-; CD8_CD38_single_positive_cells=-; CD8_count=-; CD8_HLADR_single_positive_cells=-; CD8_percent=-; CD8_HLADR_CD38_percent=-; Lymphocyte_count=-; Lymphocyte_percent=- SUBJECT_SAMPLE_FACTORS DM19-W 3_mouse Sample_Type:Humanized mouse | Lipodystrophy:- | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=3_mouse; Age=-; Gender=-; Race=-; Hispanic=-; Height=-; Weight=-; BMI=-; Adiponectin=-; Glucose=-; HDL=-; Insulin=-; LDL=-; Leptin=-; Triglycerides=-; Fasting=-; CD4_CD38_single_positive_cells=-; CD4_count=-; CD4_HLADR_single_positive_cells=-; CD4_percent=-; CD4_HLADR_CD38_percent=-; CD8_CD38_single_positive_cells=-; CD8_count=-; CD8_HLADR_single_positive_cells=-; CD8_percent=-; CD8_HLADR_CD38_percent=-; Lymphocyte_count=-; Lymphocyte_percent=- SUBJECT_SAMPLE_FACTORS 74-W 4_mouse Sample_Type:Humanized mouse | Lipodystrophy:- | HIV_status:Negative | Antiviral_Treatment:No RAW_FILE_NAME=4_mouse; Age=-; Gender=-; Race=-; Hispanic=-; Height=-; Weight=-; BMI=-; Adiponectin=-; Glucose=-; HDL=-; Insulin=-; LDL=-; Leptin=-; Triglycerides=-; Fasting=-; CD4_CD38_single_positive_cells=-; CD4_count=-; CD4_HLADR_single_positive_cells=-; CD4_percent=-; CD4_HLADR_CD38_percent=-; CD8_CD38_single_positive_cells=-; CD8_count=-; CD8_HLADR_single_positive_cells=-; CD8_percent=-; CD8_HLADR_CD38_percent=-; Lymphocyte_count=-; Lymphocyte_percent=- SUBJECT_SAMPLE_FACTORS 117-W 5_mouse Sample_Type:Humanized mouse | Lipodystrophy:- | HIV_status:Negative | Antiviral_Treatment:No RAW_FILE_NAME=5_mouse; Age=-; Gender=-; Race=-; Hispanic=-; Height=-; Weight=-; BMI=-; Adiponectin=-; Glucose=-; HDL=-; Insulin=-; LDL=-; Leptin=-; Triglycerides=-; Fasting=-; CD4_CD38_single_positive_cells=-; CD4_count=-; CD4_HLADR_single_positive_cells=-; CD4_percent=-; CD4_HLADR_CD38_percent=-; CD8_CD38_single_positive_cells=-; CD8_count=-; CD8_HLADR_single_positive_cells=-; CD8_percent=-; CD8_HLADR_CD38_percent=-; Lymphocyte_count=-; Lymphocyte_percent=- SUBJECT_SAMPLE_FACTORS 118-W 6_mouse Sample_Type:Humanized mouse | Lipodystrophy:- | HIV_status:Positive | Antiviral_Treatment:No RAW_FILE_NAME=6_mouse; Age=-; Gender=-; Race=-; Hispanic=-; Height=-; Weight=-; BMI=-; Adiponectin=-; Glucose=-; HDL=-; Insulin=-; LDL=-; Leptin=-; Triglycerides=-; Fasting=-; CD4_CD38_single_positive_cells=-; CD4_count=-; CD4_HLADR_single_positive_cells=-; CD4_percent=-; CD4_HLADR_CD38_percent=-; CD8_CD38_single_positive_cells=-; CD8_count=-; CD8_HLADR_single_positive_cells=-; CD8_percent=-; CD8_HLADR_CD38_percent=-; Lymphocyte_count=-; Lymphocyte_percent=- SUBJECT_SAMPLE_FACTORS DM9-W 7_mouse Sample_Type:Humanized mouse | Lipodystrophy:- | HIV_status:Positive | Antiviral_Treatment:Yes RAW_FILE_NAME=7_mouse; Age=-; Gender=-; Race=-; Hispanic=-; Height=-; Weight=-; BMI=-; Adiponectin=-; Glucose=-; HDL=-; Insulin=-; LDL=-; Leptin=-; Triglycerides=-; Fasting=-; CD4_CD38_single_positive_cells=-; CD4_count=-; CD4_HLADR_single_positive_cells=-; CD4_percent=-; CD4_HLADR_CD38_percent=-; CD8_CD38_single_positive_cells=-; CD8_count=-; CD8_HLADR_single_positive_cells=-; CD8_percent=-; CD8_HLADR_CD38_percent=-; Lymphocyte_count=-; Lymphocyte_percent=- SUBJECT_SAMPLE_FACTORS DM8-W 9_mouse Sample_Type:Humanized mouse | Lipodystrophy:- | HIV_status:Negative | Antiviral_Treatment:No RAW_FILE_NAME=9_mouse; Age=-; Gender=-; Race=-; Hispanic=-; Height=-; Weight=-; BMI=-; Adiponectin=-; Glucose=-; HDL=-; Insulin=-; LDL=-; Leptin=-; Triglycerides=-; Fasting=-; CD4_CD38_single_positive_cells=-; CD4_count=-; CD4_HLADR_single_positive_cells=-; CD4_percent=-; CD4_HLADR_CD38_percent=-; CD8_CD38_single_positive_cells=-; CD8_count=-; CD8_HLADR_single_positive_cells=-; CD8_percent=-; CD8_HLADR_CD38_percent=-; Lymphocyte_count=-; Lymphocyte_percent=- SUBJECT_SAMPLE_FACTORS 73-W 10_mouse Sample_Type:Humanized mouse | Lipodystrophy:- | HIV_status:Positive | Antiviral_Treatment:No RAW_FILE_NAME=10_mouse; Age=-; Gender=-; Race=-; Hispanic=-; Height=-; Weight=-; BMI=-; Adiponectin=-; Glucose=-; HDL=-; Insulin=-; LDL=-; Leptin=-; Triglycerides=-; Fasting=-; CD4_CD38_single_positive_cells=-; CD4_count=-; CD4_HLADR_single_positive_cells=-; CD4_percent=-; CD4_HLADR_CD38_percent=-; CD8_CD38_single_positive_cells=-; CD8_count=-; CD8_HLADR_single_positive_cells=-; CD8_percent=-; CD8_HLADR_CD38_percent=-; Lymphocyte_count=-; Lymphocyte_percent=- SUBJECT_SAMPLE_FACTORS PBS9.1-W 1_mouse Sample_Type:PBS Control | Lipodystrophy:- | HIV_status:- | Antiviral_Treatment:- RAW_FILE_NAME=1_mouse; Age=-; Gender=-; Race=-; Hispanic=-; Height=-; Weight=-; BMI=-; Adiponectin=-; Glucose=-; HDL=-; Insulin=-; LDL=-; Leptin=-; Triglycerides=-; Fasting=-; CD4_CD38_single_positive_cells=-; CD4_count=-; CD4_HLADR_single_positive_cells=-; CD4_percent=-; CD4_HLADR_CD38_percent=-; CD8_CD38_single_positive_cells=-; CD8_count=-; CD8_HLADR_single_positive_cells=-; CD8_percent=-; CD8_HLADR_CD38_percent=-; Lymphocyte_count=-; Lymphocyte_percent=- SUBJECT_SAMPLE_FACTORS PBS9.2-W 8_mouse Sample_Type:PBS Control | Lipodystrophy:- | HIV_status:- | Antiviral_Treatment:- RAW_FILE_NAME=8_mouse; Age=-; Gender=-; Race=-; Hispanic=-; Height=-; Weight=-; BMI=-; Adiponectin=-; Glucose=-; HDL=-; Insulin=-; LDL=-; Leptin=-; Triglycerides=-; Fasting=-; CD4_CD38_single_positive_cells=-; CD4_count=-; CD4_HLADR_single_positive_cells=-; CD4_percent=-; CD4_HLADR_CD38_percent=-; CD8_CD38_single_positive_cells=-; CD8_count=-; CD8_HLADR_single_positive_cells=-; CD8_percent=-; CD8_HLADR_CD38_percent=-; Lymphocyte_count=-; Lymphocyte_percent=- #COLLECTION CO:COLLECTION_SUMMARY Whole blood was collected in sodium heparin vacutainers and centrifuged at CO:COLLECTION_SUMMARY 1700rpm for 10 minutes for plasma collection. Plasma was aliquoted into 1mL CO:COLLECTION_SUMMARY microcentrifuge tubes and stored at -80. CO:SAMPLE_TYPE Blood (plasma) CO:STORAGE_CONDITIONS -80℃ #TREATMENT TR:TREATMENT_SUMMARY n/a #SAMPLEPREP SP:SAMPLEPREP_SUMMARY See uploaded file #CHROMATOGRAPHY CH:CHROMATOGRAPHY_TYPE Reversed phase CH:INSTRUMENT_NAME Agilent 6545 QTOF CH:COLUMN_NAME Agilent Zorbax RRHD SB-C18 (100 x 2.1mm, 1.8um) #ANALYSIS AN:ANALYSIS_TYPE MS #MS MS:INSTRUMENT_NAME new MS:INSTRUMENT_TYPE QTOF MS:MS_TYPE ESI MS:ION_MODE POSITIVE MS:MS_COMMENTS attached MS:MS_RESULTS_FILE ST001750_AN002853_Results.txt UNITS:Abundance (Mass Spectral Counts) Has m/z:Neutral masses Has RT:Yes RT units:Minutes #END