#METABOLOMICS WORKBENCH alhughes3_20210722_081823 DATATRACK_ID:2764 STUDY_ID:ST001901 ANALYSIS_ID:AN003090 VERSION 1 CREATED_ON 02-08-2024 #PROJECT PR:PROJECT_TITLE Mitochondrial-Derived Compartments Facilitate Cellular Adaptation to Amino Acid PR:PROJECT_TITLE Stress PR:PROJECT_SUMMARY Amino acids are essential building blocks of life. However, increasing evidence PR:PROJECT_SUMMARY suggests that elevated amino acids cause cellular toxicity associated with PR:PROJECT_SUMMARY numerous metabolic disorders. How cells cope with elevated amino acids remains PR:PROJECT_SUMMARY poorly understood. Here, we show that a previously identified cellular PR:PROJECT_SUMMARY structure, the mitochondrial-derived compartment (MDC), functions to protect PR:PROJECT_SUMMARY cells from amino acid stress. In response to amino acid elevation, MDCs are PR:PROJECT_SUMMARY generated from mitochondria, where they selectively sequester and deplete SLC25A PR:PROJECT_SUMMARY nutrient carriers and their associated import receptor Tom70 from the organelle. PR:PROJECT_SUMMARY Generation of MDCs promotes amino acid catabolism, and their formation occurs PR:PROJECT_SUMMARY simultaneously with transporter removal at the plasma membrane via the PR:PROJECT_SUMMARY multi-vesicular body (MVB) pathway. Combined loss of vacuolar amino acid PR:PROJECT_SUMMARY storage, MVBs and MDCs renders cells sensitive to high amino acid stress. Thus, PR:PROJECT_SUMMARY we propose that MDCs operate as part of a coordinated cell network that PR:PROJECT_SUMMARY facilitates amino acid homoeostasis through post-translational nutrient PR:PROJECT_SUMMARY transporter remodeling. PR:INSTITUTE University of Utah School of Medicine PR:DEPARTMENT Biochemistry PR:LABORATORY Hughes Lab PR:LAST_NAME Hughes PR:FIRST_NAME Adam PR:ADDRESS 15 N Medical Drive East, RM 4100, Salt Lake City, UT, 84112, USA PR:EMAIL hughes@biochem.utah.edu PR:PHONE 8015812481 PR:DOI http://dx.doi.org/10.21228/M83X4N #STUDY ST:STUDY_TITLE Mitochondrial-Derived Compartments Facilitate Cellular Adaptation to Amino Acid ST:STUDY_TITLE Stress ST:STUDY_SUMMARY Amino acids are essential building blocks of life. However, increasing evidence ST:STUDY_SUMMARY suggests that elevated amino acids cause cellular toxicity associated with ST:STUDY_SUMMARY numerous metabolic disorders. How cells cope with elevated amino acids remains ST:STUDY_SUMMARY poorly understood. Here, we show that a previously identified cellular ST:STUDY_SUMMARY structure, the mitochondrial-derived compartment (MDC), functions to protect ST:STUDY_SUMMARY cells from amino acid stress. In response to amino acid elevation, MDCs are ST:STUDY_SUMMARY generated from mitochondria, where they selectively sequester and deplete SLC25A ST:STUDY_SUMMARY nutrient carriers and their associated import receptor Tom70 from the organelle. ST:STUDY_SUMMARY Generation of MDCs promotes amino acid catabolism, and their formation occurs ST:STUDY_SUMMARY simultaneously with transporter removal at the plasma membrane via the ST:STUDY_SUMMARY multi-vesicular body (MVB) pathway. Combined loss of vacuolar amino acid ST:STUDY_SUMMARY storage, MVBs and MDCs renders cells sensitive to high amino acid stress. Thus, ST:STUDY_SUMMARY we propose that MDCs operate as part of a coordinated cell network that ST:STUDY_SUMMARY facilitates amino acid homoeostasis through post-translational nutrient ST:STUDY_SUMMARY transporter remodeling. ST:INSTITUTE University of Utah School of Medicine ST:DEPARTMENT Biochemistry ST:LABORATORY Hughes Lab ST:LAST_NAME Hughes ST:FIRST_NAME Adam ST:ADDRESS 15 N Medical Drive East, RM 4100, Salt Lake City, UT, 84112, USA ST:EMAIL hughes@biochem.utah.edu ST:PHONE 8015812481 ST:SUBMIT_DATE 2021-07-22 #SUBJECT SU:SUBJECT_TYPE Yeast SU:SUBJECT_SPECIES Saccharomyces cerevisiae SU:TAXONOMY_ID 4932 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_6A Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_6B Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_6C Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_6D Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_2A Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_2B Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_2C Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_2D Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_11 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_11.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_17 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_17.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_23 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_23.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5a Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5a.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_11 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_11.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_17 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_17.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_23 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_23.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_5 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_5.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_10 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_10.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_16 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_16.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_22 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_22.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_4 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_4.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_10 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_10.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_16 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_16.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_22 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_22.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_4 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_4.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_12 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_12.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_18 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_18.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_24 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_24.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_12 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_12.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_18 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_18.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_24 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_24.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_6 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_6.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_4D Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_8A Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_8B Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_8C Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_8D Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_4A Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_4B Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_4C Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_QC5 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC5.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_QC6 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC6.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_QC7 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC7.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_QC8 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC8.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC1 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC1.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC2 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC2.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC3 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC3.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC4 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC4.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_QC1 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC1.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_QC2 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC2.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_QC3 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC3.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_QC4 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC4.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_QC1 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC1.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_QC2 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC2.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_QC3 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC3.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_QC4 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC4.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_PB4 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_PB4.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_PB5 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_PB5.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_PB6 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_PB6.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB1 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB1.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB2 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB2.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB3 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB3.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB4 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB4.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_PB1 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB1.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_PB2 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB2.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_PB3 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB3.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_PB4 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB4.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_PB1 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB1.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_PB2 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB2.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_PB3 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB3.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_PB4 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB4.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_7A Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_7B Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_7C Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_7D Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_3A Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_3B Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_3C Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_3D Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_34 Genotype:wild-type | Media:MinD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_34.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_43 Genotype:wild-type | Media:MinD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_43.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_52 Genotype:wild-type | Media:MinD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_52.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_5A Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_5B Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_5C Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_5D Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_1A Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1A.D; Experiment identifier=MDCY-205; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_1B Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_1C Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_1D Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_31 Genotype:wild-type | Media:SD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_31.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_40 Genotype:wild-type | Media:SD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_40.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_49 Genotype:wild-type | Media:SD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_49.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_14 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_14.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_2 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_2.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_20 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_20.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_8 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_8.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_14 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_14.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_2 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_2.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_20 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_20.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_8 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_8.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_28 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_28.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_37 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_37.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_46 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_46.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_1 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_1.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_13 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_13.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_19 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_19.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_7 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_7.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_1 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_1.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_13 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_13.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_19 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_19.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_7 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_7.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_15 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_15.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_21 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_21.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_3 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_3.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_9 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_9.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_15 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_15.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_21 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_21.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_3 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_3.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_9 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_9.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E #COLLECTION CO:COLLECTION_SUMMARY See STAR methods file CO:COLLECTION_PROTOCOL_FILENAME STAR_methods.pdf CO:SAMPLE_TYPE Yeast cells #TREATMENT TR:TREATMENT_SUMMARY See STAR Methods file TR:TREATMENT_PROTOCOL_FILENAME STAR_methods.pdf #SAMPLEPREP SP:SAMPLEPREP_SUMMARY See STAR Methods file SP:SAMPLEPREP_PROTOCOL_FILENAME STAR_methods.pdf #CHROMATOGRAPHY CH:INSTRUMENT_NAME Agilent 7200 CH:COLUMN_NAME Phenomenex Zebron ZB-WAXplus (30m x 0.25mm,0.25um) CH:CHROMATOGRAPHY_TYPE GC #ANALYSIS AN:ANALYSIS_TYPE MS #MS MS:INSTRUMENT_NAME Agilent 7200 MS:INSTRUMENT_TYPE QTOF MS:MS_TYPE EI MS:MS_COMMENTS N/A MS:ION_MODE POSITIVE #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS area under the curve MS_METABOLITE_DATA_START Samples Hughes_Schuler_20200818_7200_20to1_Yeast_6A Hughes_Schuler_20200818_7200_20to1_Yeast_6B Hughes_Schuler_20200818_7200_20to1_Yeast_6C Hughes_Schuler_20200818_7200_20to1_Yeast_6D Hughes_Schuler_20200818_7200_20to1_Yeast_2A Hughes_Schuler_20200818_7200_20to1_Yeast_2B Hughes_Schuler_20200818_7200_20to1_Yeast_2C Hughes_Schuler_20200818_7200_20to1_Yeast_2D Hughes_Schuler_20200818_7200_20to1_Yeast_4D Hughes_Schuler_20200818_7200_20to1_Yeast_8A Hughes_Schuler_20200818_7200_20to1_Yeast_8B Hughes_Schuler_20200818_7200_20to1_Yeast_8C Hughes_Schuler_20200818_7200_20to1_Yeast_8D Hughes_Schuler_20200818_7200_20to1_Yeast_4A Hughes_Schuler_20200818_7200_20to1_Yeast_4B Hughes_Schuler_20200818_7200_20to1_Yeast_4C Hughes_Schuler_20200818_7200_20to1_Yeast_QC1 Hughes_Schuler_20200818_7200_20to1_Yeast_QC2 Hughes_Schuler_20200818_7200_20to1_Yeast_QC3 Hughes_Schuler_20200818_7200_20to1_Yeast_QC4 Hughes_Schuler_20200818_7200_20to1_Yeast_PB1 Hughes_Schuler_20200818_7200_20to1_Yeast_PB2 Hughes_Schuler_20200818_7200_20to1_Yeast_PB3 Hughes_Schuler_20200818_7200_20to1_Yeast_PB4 Hughes_Schuler_20200818_7200_20to1_Yeast_7A Hughes_Schuler_20200818_7200_20to1_Yeast_7B Hughes_Schuler_20200818_7200_20to1_Yeast_7C Hughes_Schuler_20200818_7200_20to1_Yeast_7D Hughes_Schuler_20200818_7200_20to1_Yeast_3A Hughes_Schuler_20200818_7200_20to1_Yeast_3B Hughes_Schuler_20200818_7200_20to1_Yeast_3C Hughes_Schuler_20200818_7200_20to1_Yeast_3D Hughes_Schuler_20200818_7200_20to1_Yeast_5A Hughes_Schuler_20200818_7200_20to1_Yeast_5B Hughes_Schuler_20200818_7200_20to1_Yeast_5C Hughes_Schuler_20200818_7200_20to1_Yeast_5D Hughes_Schuler_20200818_7200_20to1_Yeast_1A Hughes_Schuler_20200818_7200_20to1_Yeast_1B Hughes_Schuler_20200818_7200_20to1_Yeast_1C Hughes_Schuler_20200818_7200_20to1_Yeast_1D Factors Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO Genotype:Pooled QC sample | Media:N/A | Treatment:N/A Genotype:Pooled QC sample | Media:N/A | Treatment:N/A Genotype:Pooled QC sample | Media:N/A | Treatment:N/A Genotype:Pooled QC sample | Media:N/A | Treatment:N/A Genotype:Process blank | Media:N/A | Treatment:N/A Genotype:Process blank | Media:N/A | Treatment:N/A Genotype:Process blank | Media:N/A | Treatment:N/A Genotype:Process blank | Media:N/A | Treatment:N/A Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO 1-Palmitoylglycerol 18286.0000 14116.0000 20582.0000 11260.0000 22345.0000 26029.0000 17557.0000 60850.0000 16539.0000 20963.0000 15968.0000 19470.0000 48697.0000 14698.0000 13354.0000 21949.0000 16327.0000 11489.0000 13097.0000 38744.0000 20613.0000 6459.0000 6969.0000 23783.0000 34037.0000 16697.0000 25276.0000 38459.0000 22316.0000 21118.0000 17260.0000 37662.0000 18094.0000 13290.0000 21824.0000 31421.0000 23285.0000 30987.0000 21385.0000 1-Steroylglycerol 7032.0000 5493.0000 9942.0000 4970.0000 8778.0000 10631.0000 8609.0000 30069.0000 7031.0000 8560.0000 7063.0000 8994.0000 22990.0000 5725.0000 5315.0000 9331.0000 7174.0000 5505.0000 6211.0000 16615.0000 5389.0000 2342.0000 3149.0000 9350.0000 14307.0000 6850.0000 10867.0000 15551.0000 9893.0000 9411.0000 7637.0000 19000.0000 8795.0000 4945.0000 8670.0000 13229.0000 10475.0000 13954.0000 10475.0000 2^3^-Bisphosphoglycerate 2-Aminoadipic acid 592.0000 73.0000 93.0000 1003.0000 2-Hydroxybenzoic acid 1362.0000 1259.0000 2553.0000 1706.0000 1308.0000 963.0000 1231.0000 1648.0000 1541.0000 1149.0000 775.0000 845.0000 1571.0000 2332.0000 1603.0000 1814.0000 2393.0000 1235.0000 221.0000 918.0000 1026.0000 2-Hydroxybutyric acid 1389.0000 2286.0000 3503.0000 1284.0000 2289.0000 3094.0000 1872.0000 1890.0000 1799.0000 721.0000 1209.0000 207.0000 2257.0000 2312.0000 5731.0000 718.0000 1790.0000 1862.0000 774.0000 2070.0000 891.0000 258.0000 2-Hydroxyglutaric acid 13.0000 2-Ketoglutarate 5008.0000 10396.0000 13792.0000 8464.0000 13983.0000 14005.0000 24109.0000 46930.0000 24071.0000 5888.0000 7633.0000 10746.0000 10693.0000 18308.0000 17450.0000 18467.0000 9988.0000 5576.0000 5975.0000 9136.0000 10858.0000 8742.0000 10944.0000 21006.0000 27784.0000 33340.0000 30534.0000 66553.0000 6581.0000 9478.0000 10253.0000 29793.0000 15100.0000 20831.0000 37286.0000 2-Monopalmitoylglycerol 908.0000 1322.0000 116.0000 452.0000 2-Steroylglycerol 3-Hydroxybutyrate 5795.0000 3195.0000 2039.0000 1561.0000 560.0000 6874.0000 187.0000 4818.0000 6848.0000 7945.0000 7942.0000 3780.0000 6759.0000 4146.0000 3036.0000 4151.0000 18325.0000 4736.0000 8333.0000 6607.0000 85.0000 2762.0000 3364.0000 88.0000 3-Phosphoglyceric acid 511.0000 854.0000 1832.0000 788.0000 1709.0000 1726.0000 2569.0000 6331.0000 2931.0000 890.0000 1047.0000 1741.0000 2174.0000 2166.0000 1768.0000 2525.0000 1881.0000 1489.0000 1520.0000 2856.0000 762.0000 619.0000 1034.0000 2628.0000 2539.0000 2841.0000 2539.0000 6583.0000 422.0000 604.0000 1255.0000 2289.0000 1858.0000 2161.0000 4120.0000 4-Hydroxyproline 1 4-Hydroxyproline 2 5-Hydroxytryptophan Adenine 28.0000 620.0000 315.0000 Adenosine 746.0000 3264.0000 3037.0000 2157.0000 1780.0000 1782.0000 2486.0000 11073.0000 4526.0000 1331.0000 1610.0000 2100.0000 4193.0000 2375.0000 2437.0000 3258.0000 2012.0000 1317.0000 2702.0000 3395.0000 232.0000 2340.0000 2462.0000 3109.0000 7789.0000 1454.0000 2845.0000 2980.0000 9146.0000 1210.0000 1606.0000 3201.0000 4229.0000 1697.0000 2329.0000 3204.0000 Adenosine 3^-monophosphate 35.0000 120922.0000 51.0000 82.0000 75565.0000 Adenosine 5^-monophosphate 35.0000 51.0000 82.0000 Adipic acid 678.0000 844.0000 995.0000 496.0000 207.0000 531.0000 14569.0000 1182.0000 559.0000 747.0000 1338.0000 10801.0000 505.0000 679.0000 436.0000 1072.0000 787.0000 883.0000 6532.0000 6135.0000 1276.0000 3365.0000 36820.0000 483.0000 295.0000 21032.0000 634.0000 1365.0000 951.0000 9514.0000 311.0000 637.0000 12202.0000 374.0000 498.0000 860.0000 Allantoin 232.0000 284.0000 Arachidic acid 1581.0000 1681.0000 134.0000 4511.0000 5671.0000 2063.0000 2369.0000 2420.0000 1171.0000 701.0000 1080.0000 1672.0000 784.0000 1695.0000 273.0000 1198.0000 1969.0000 1288.0000 2464.0000 183.0000 1176.0000 6266.0000 5736.0000 Arachidonic acid Ascorbic acid 469.0000 220.0000 525.0000 460.0000 509.0000 182.0000 997.0000 271.0000 139.0000 Benzoic acid 12416.0000 25653.0000 17117.0000 23795.0000 10754.0000 22555.0000 27216.0000 24338.0000 29366.0000 19645.0000 27185.0000 33492.0000 23153.0000 15863.0000 22386.0000 34989.0000 37962.0000 21882.0000 32934.0000 28086.0000 71437.0000 21072.0000 26956.0000 21379.0000 27106.0000 28743.0000 28750.0000 22030.0000 25596.0000 32227.0000 31000.0000 21514.0000 12963.0000 22713.0000 23990.0000 23978.0000 12279.0000 24279.0000 25181.0000 Beta-Alanine 172.0000 349.0000 137.0000 101.0000 402.0000 96.0000 453.0000 202.0000 220.0000 343.0000 250.0000 80.0000 219.0000 425.0000 346.0000 310.0000 785.0000 329.0000 286.0000 231.0000 103.0000 404.0000 347.0000 Beta-Amino Isobutyric acid Beta-Lactate 3626.0000 2678.0000 874.0000 3768.0000 Beta-Sitosterol C20:3 A C20:3 B Campesterol Capric acid 2338.0000 2664.0000 2448.0000 3939.0000 3867.0000 3127.0000 3169.0000 2526.0000 1944.0000 3392.0000 2345.0000 3869.0000 3463.0000 4083.0000 12117.0000 2147.0000 3563.0000 3061.0000 2831.0000 2482.0000 2582.0000 2882.0000 2744.0000 3206.0000 3792.0000 3319.0000 1806.0000 2849.0000 3157.0000 2596.0000 2810.0000 Cholesterol cis-Aconitic acid Citric acid 8821.0000 11873.0000 17396.0000 8580.0000 14251.0000 12908.0000 16442.0000 30110.0000 17176.0000 11388.0000 13301.0000 18894.0000 20707.0000 14313.0000 12156.0000 15922.0000 12739.0000 7029.0000 7039.0000 14689.0000 4107.0000 2909.0000 5021.0000 10237.0000 6660.0000 6725.0000 7193.0000 14031.0000 2252.0000 2065.0000 4528.0000 7304.0000 4731.0000 5639.0000 6828.0000 Creatinine Cystathionine 1722.0000 4381.0000 8945.0000 2509.0000 3856.0000 3131.0000 7294.0000 40597.0000 13967.0000 9072.0000 14395.0000 41731.0000 42735.0000 14704.0000 19272.0000 23747.0000 3765.0000 3469.0000 4510.0000 11715.0000 5740.0000 405.0000 1342.0000 3531.0000 12786.0000 3549.0000 5522.0000 16103.0000 5284.0000 15530.0000 8083.0000 106837.0000 3113.0000 3736.0000 7533.0000 7903.0000 2966.0000 3556.0000 7021.0000 d4-succinate 17979.0000 25503.0000 33898.0000 18142.0000 33887.0000 29632.0000 37768.0000 61086.0000 39632.0000 31572.0000 28173.0000 34962.0000 39171.0000 33356.0000 30514.0000 32320.0000 27481.0000 14580.0000 27976.0000 31239.0000 44740.0000 9749.0000 25052.0000 42185.0000 36080.0000 18288.0000 24296.0000 48710.0000 34408.0000 33376.0000 29198.0000 60894.0000 24237.0000 21165.0000 32737.0000 62749.0000 30081.0000 35496.0000 38491.0000 479.0000 Dehydroascorbic acid 1665.0000 395.0000 2994.0000 2079.0000 677.0000 3496.0000 2663.0000 3007.0000 3707.0000 2032.0000 2556.0000 3879.0000 3914.0000 2966.0000 5598.0000 D-Fructose 1 4004.0000 7258.0000 11036.0000 7117.0000 4988.0000 9080.0000 9272.0000 15933.0000 7034.0000 8312.0000 7766.0000 11687.0000 15319.0000 6664.0000 7432.0000 7850.0000 11711.0000 6820.0000 6784.0000 14880.0000 6551.0000 2068.0000 6018.0000 6340.0000 6319.0000 5736.0000 8041.0000 14941.0000 7972.0000 10562.0000 7199.0000 19507.0000 3085.0000 5525.0000 7282.0000 18140.0000 4442.0000 9097.0000 6814.0000 D-Fructose 2 3176.0000 5132.0000 9469.0000 5252.0000 4834.0000 3648.0000 4606.0000 11223.0000 5481.0000 3651.0000 4353.0000 6690.0000 8734.0000 1999.0000 4402.0000 2519.0000 5894.0000 3267.0000 2468.0000 8179.0000 4728.0000 1182.0000 5039.0000 4448.0000 3519.0000 3790.0000 4009.0000 12022.0000 5998.0000 7801.0000 5277.0000 10912.0000 3159.0000 5175.0000 7370.0000 10377.0000 1702.0000 4549.0000 2535.0000 D-Glucose 1 3474910.0000 7200973.0000 7807880.0000 3726399.0000 7367384.0000 7198325.0000 7450948.0000 5013248.0000 7698885.0000 7362229.0000 7725716.0000 4062341.0000 9565559.0000 3414993.0000 7118319.0000 3490073.0000 3174052.0000 7030869.0000 3448689.0000 4120084.0000 2794800.0000 3309158.0000 3858333.0000 3526291.0000 3201846.0000 7155175.0000 7603148.0000 3676640.0000 3485661.0000 3599998.0000 3570561.0000 4770885.0000 5572850.0000 3367129.0000 7209178.0000 3619073.0000 4803836.0000 7397500.0000 5697794.0000 514171.0000 D-Glucose 2 1206320.0000 2757037.0000 3295884.0000 3478975.0000 3041709.0000 3098783.0000 2903114.0000 4744972.0000 3144705.0000 3193683.0000 3503946.0000 3705462.0000 4429155.0000 768671.0000 2459474.0000 2616613.0000 4755054.0000 3038308.0000 2795827.0000 4437086.0000 2604004.0000 1500187.0000 4147496.0000 4897642.0000 2148947.0000 3170625.0000 3277563.0000 3468706.0000 4181771.0000 3169756.0000 2108615.0000 4144861.0000 855288.0000 2778384.0000 2825500.0000 5024590.0000 671465.0000 3187680.0000 963503.0000 75680.0000 DHAP 267.0000 Diethyl Phthalate Disaccharide 1 2616.0000 3516.0000 1618.0000 1658.0000 2230.0000 4340.0000 3138.0000 4253.0000 4660.0000 5629.0000 8147.0000 2839.0000 2376.0000 3345.0000 3273.0000 4133.0000 5111.0000 2531.0000 3806.0000 9156.0000 3441.0000 3261.0000 3233.0000 6362.0000 2047.0000 2753.0000 4804.0000 1416.0000 2121.0000 Disaccharide 2 2616.0000 3516.0000 1618.0000 1658.0000 2230.0000 4340.0000 3138.0000 4253.0000 4660.0000 5629.0000 8147.0000 2839.0000 2376.0000 3345.0000 3273.0000 4133.0000 5111.0000 2531.0000 3806.0000 9156.0000 3441.0000 3261.0000 3233.0000 6362.0000 2047.0000 2753.0000 4804.0000 1416.0000 2121.0000 D-Malic acid 3456.0000 3930.0000 6845.0000 2563.0000 5506.0000 4734.0000 7191.0000 11352.0000 3812.0000 3354.0000 3474.0000 3748.0000 4613.0000 3504.0000 2723.0000 3505.0000 8273.0000 4832.0000 4689.0000 10447.0000 7592.0000 5145.0000 7456.0000 10217.0000 4455.0000 3931.0000 3915.0000 7586.0000 10431.0000 7041.0000 11266.0000 16963.0000 4349.0000 7001.0000 8194.0000 D-Mannose 3474910.0000 7200973.0000 7807880.0000 3723772.0000 7367384.0000 7198325.0000 7450948.0000 5591178.0000 7698885.0000 7362229.0000 7725716.0000 4315162.0000 9565559.0000 788535.0000 7118319.0000 3986566.0000 3549244.0000 7030869.0000 3609793.0000 4279524.0000 3309584.0000 3676177.0000 3723308.0000 4820124.0000 3947431.0000 7155175.0000 7603148.0000 5303779.0000 4098408.0000 4203225.0000 3482106.0000 5083855.0000 5572850.0000 3640354.0000 7209178.0000 5150273.0000 4803836.0000 7397500.0000 5697794.0000 D-Threitol 16675.0000 22512.0000 29004.0000 14170.0000 13702.0000 12427.0000 15919.0000 31789.0000 19282.0000 29606.0000 24421.0000 34742.0000 41534.0000 19019.0000 17069.0000 20915.0000 23598.0000 14979.0000 19628.0000 32441.0000 6256.0000 1373.0000 2985.0000 4565.0000 41864.0000 28097.0000 35776.0000 64177.0000 19398.0000 17444.0000 16229.0000 36320.0000 28089.0000 21674.0000 35302.0000 62672.0000 10946.0000 12159.0000 13718.0000 45.0000 Elaidic acid 9661.0000 7351.0000 9364.0000 6248.0000 9064.0000 14209.0000 12436.0000 6511.0000 12839.0000 11196.0000 11985.0000 9991.0000 5526.0000 9087.0000 7018.0000 9533.0000 7595.0000 7196.0000 9483.0000 6622.0000 32017.0000 3414.0000 2840.0000 9881.0000 15193.0000 12047.0000 14479.0000 5734.0000 9462.0000 10728.0000 9105.0000 6561.0000 13114.0000 5382.0000 9487.0000 11110.0000 14374.0000 13574.0000 14641.0000 Ergosterol 901.0000 3050.0000 3059.0000 1706.0000 3255.0000 111.0000 1365.0000 3536.0000 2951.0000 602.0000 2856.0000 2174.0000 3536.0000 4783.0000 Ethanolamine 1 148743.0000 139219.0000 84183.0000 112043.0000 180269.0000 146741.0000 100470.0000 18571.0000 98304.0000 128461.0000 127866.0000 96189.0000 25327.0000 146563.0000 95789.0000 101571.0000 220367.0000 138499.0000 111430.0000 20668.0000 293323.0000 203670.0000 209789.0000 38599.0000 104268.0000 124182.0000 103102.0000 37308.0000 201889.0000 112058.0000 92331.0000 21926.0000 120535.0000 120770.0000 77154.0000 38275.0000 146874.0000 150042.0000 114926.0000 Ethanolamine 2 170330.0000 168686.0000 226138.0000 195352.0000 209630.0000 205287.0000 251579.0000 351849.0000 238249.0000 178479.0000 194267.0000 215901.0000 368557.0000 207701.0000 187483.0000 232862.0000 252195.0000 172879.0000 215650.0000 369213.0000 311269.0000 146157.0000 152494.0000 318462.0000 184939.0000 162700.0000 211688.0000 158752.0000 185062.0000 193243.0000 198403.0000 324314.0000 159009.0000 143947.0000 171349.0000 233192.0000 184690.0000 200208.0000 209067.0000 8977.0000 Fructose-6-phosphate 575.0000 1052.0000 481.0000 456.0000 168.0000 Fumaric acid 18185.0000 20625.0000 29780.0000 15384.0000 28755.0000 30112.0000 36112.0000 56057.0000 24875.0000 21477.0000 18022.0000 23594.0000 30533.0000 19061.0000 15278.0000 18463.0000 40510.0000 23617.0000 24474.0000 46803.0000 12804.0000 3455.0000 4524.0000 3889.0000 36146.0000 27449.0000 41390.0000 57529.0000 23592.0000 21671.0000 20799.0000 34553.0000 39999.0000 29292.0000 46510.0000 77458.0000 30065.0000 36676.0000 39802.0000 GABA 1731.0000 2269.0000 2662.0000 1686.0000 2224.0000 2055.0000 1961.0000 1638.0000 2249.0000 2819.0000 2561.0000 2640.0000 2078.0000 2255.0000 2483.0000 2635.0000 3688.0000 2192.0000 2189.0000 3328.0000 213.0000 101.0000 3100.0000 2175.0000 2894.0000 2372.0000 2244.0000 2666.0000 2330.0000 2167.0000 1582.0000 2067.0000 806.0000 1920.0000 2035.0000 1791.0000 Galactosamine Gluconic acid 81.0000 42.0000 Glucose 6-phosphate 30389.0000 27782.0000 59717.0000 29702.0000 52911.0000 42537.0000 61679.0000 191340.0000 55915.0000 39439.0000 39994.0000 55306.0000 89868.0000 38152.0000 30709.0000 47816.0000 64765.0000 39351.0000 41160.0000 97310.0000 36003.0000 25336.0000 45751.0000 79338.0000 66500.0000 48413.0000 48481.0000 136792.0000 27933.0000 22851.0000 31805.0000 81164.0000 34657.0000 48947.0000 69697.0000 331.0000 Glutamic acid 17.0000 1738.0000 815.0000 389.0000 2554.0000 195.0000 Glutamine 6523.0000 2803.0000 5287.0000 471.0000 923.0000 5678.0000 5490.0000 602.0000 26623.0000 8548.0000 11334.0000 15608.0000 22865.0000 18554.0000 3441.0000 5754.0000 3547.0000 60343.0000 16104.0000 5028.0000 1604.0000 11625.0000 8386.0000 6447.0000 3024.0000 3525.0000 5893.0000 3505.0000 4632.0000 Glycerol 35728.0000 210213.0000 206380.0000 126522.0000 163619.0000 97055.0000 246392.0000 158633.0000 144740.0000 94325.0000 120171.0000 161370.0000 132897.0000 272115.0000 201943.0000 205072.0000 65259.0000 33960.0000 182769.0000 61826.0000 3878.0000 862.0000 1926.0000 1065.0000 256777.0000 35438.0000 43420.0000 233248.0000 254420.0000 256851.0000 250186.0000 212446.0000 100403.0000 232555.0000 312224.0000 347934.0000 159027.0000 156902.0000 150969.0000 7587.0000 Glycerol 3-phosphate 543.0000 1176.0000 2612.0000 1091.0000 2018.0000 1424.0000 2737.0000 6661.0000 2630.0000 1120.0000 1327.0000 2142.0000 2392.0000 1707.0000 1620.0000 2702.0000 2652.0000 1357.0000 2081.0000 3404.0000 1699.0000 704.0000 1177.0000 4751.0000 2720.0000 3396.0000 3490.0000 7524.0000 1332.0000 1570.0000 2740.0000 3971.0000 2271.0000 2812.0000 5275.0000 Glycine 83262.0000 83445.0000 119045.0000 69848.0000 102995.0000 84342.0000 107508.0000 183249.0000 132277.0000 161463.0000 132370.0000 157261.0000 196632.0000 130566.0000 102904.0000 122526.0000 171595.0000 93206.0000 85614.0000 170761.0000 59341.0000 14041.0000 28117.0000 39660.0000 116760.0000 93442.0000 117804.0000 118548.0000 122966.0000 93162.0000 88449.0000 158710.0000 54140.0000 49528.0000 67818.0000 111948.0000 64148.0000 76570.0000 92370.0000 3427.0000 Glycolic acid Glyoxylic acid 1657.0000 1662.0000 1099.0000 1424.0000 1559.0000 1550.0000 344.0000 1231.0000 1480.0000 222.0000 1486.0000 137.0000 1442.0000 1026.0000 2477.0000 1025.0000 456.0000 3900.0000 1572.0000 1585.0000 423.0000 1051.0000 2216.0000 1438.0000 1102.0000 1435.0000 404.0000 1469.0000 1020.0000 1089.0000 1137.0000 1022.0000 1231.0000 110.0000 Heptadecanoic acid 10193.0000 1064.0000 5424.0000 1713.0000 26960.0000 30698.0000 4113.0000 32865.0000 9061.0000 12022.0000 4504.0000 8.0000 6931.0000 2356.0000 976.0000 2075.0000 2384.0000 3620.0000 4374.0000 6838.0000 1547.0000 257.0000 767.0000 36760.0000 3086.0000 5530.0000 10322.0000 24162.0000 3126.0000 1841.0000 27558.0000 9983.0000 1307.0000 5386.0000 8083.0000 27725.0000 37080.0000 8312.0000 Hypotaurine Hypoxanthine 421.0000 1716.0000 3017.0000 2087.0000 3305.0000 7688.0000 985.0000 1264.0000 1459.0000 2442.0000 2245.0000 1140.0000 1020.0000 1508.0000 836.0000 1206.0000 1005.0000 1891.0000 944.0000 324.0000 935.0000 198.0000 68.0000 2051.0000 1385.0000 3814.0000 134.0000 518.0000 3498.0000 5472.0000 5883.0000 Inosine 1444.0000 2124.0000 3909.0000 1462.0000 4336.0000 3203.0000 6539.0000 15235.0000 9101.0000 2124.0000 1853.0000 3402.0000 4828.0000 8468.0000 7895.0000 13850.0000 2499.0000 2369.0000 3237.0000 7850.0000 50.0000 874.0000 548.0000 1203.0000 2381.0000 7524.0000 6529.0000 9878.0000 26343.0000 602.0000 1557.0000 2734.0000 4417.0000 6129.0000 Inositol phosphate 31920.0000 20219.0000 69656.0000 29119.0000 62926.0000 53712.0000 75190.0000 364468.0000 81708.0000 54339.0000 56858.0000 69485.0000 185580.0000 35409.0000 34156.0000 70744.0000 49176.0000 38570.0000 47395.0000 176134.0000 964.0000 1225.0000 1792.0000 51252.0000 47139.0000 93310.0000 166565.0000 64745.0000 60487.0000 39269.0000 305331.0000 43882.0000 33718.0000 61787.0000 181284.0000 48377.0000 69247.0000 100593.0000 985.0000 Isocitric acid 2659.0000 3041.0000 5743.0000 2439.0000 4449.0000 3806.0000 5987.0000 12759.0000 6177.0000 4545.0000 4155.0000 6214.0000 9916.0000 5089.0000 4427.0000 5143.0000 5043.0000 2696.0000 3429.0000 7926.0000 2803.0000 2071.0000 2752.0000 207.0000 2919.0000 3351.0000 3138.0000 968.0000 959.0000 2321.0000 3262.0000 4638.0000 2802.0000 5478.0000 L-Alanine 1 3425891.0000 4181920.0000 5844648.0000 3179325.0000 3350784.0000 3138859.0000 4214784.0000 4899517.0000 6085053.0000 6554714.0000 7140325.0000 9096158.0000 6293865.0000 5856372.0000 5671003.0000 7091194.0000 4924040.0000 3849874.0000 3936956.0000 3269150.0000 755405.0000 238373.0000 510860.0000 201256.0000 5915611.0000 4703956.0000 5723315.0000 6462517.0000 3757911.0000 4899591.0000 4410566.0000 6631630.0000 1766307.0000 1964198.0000 3394736.0000 2358157.0000 2169315.0000 2908480.0000 3735546.0000 82343.0000 L-Alanine 2 455.0000 345.0000 76.0000 557.0000 528.0000 595.0000 314.0000 427.0000 730.0000 Lanthionine L-Asparagine 6806.0000 5132.0000 12249.0000 1804.0000 8473.0000 9514.0000 13628.0000 12381.0000 18002.0000 7500.0000 10535.0000 12324.0000 19900.0000 20557.0000 18934.0000 10841.0000 8299.0000 5495.0000 11352.0000 10524.0000 5783.0000 3956.0000 12008.0000 12745.0000 12130.0000 37633.0000 4380.0000 2359.0000 4393.0000 8328.0000 8507.0000 11948.0000 L-Aspartic acid 1 1430541.0000 1763351.0000 2507991.0000 1201928.0000 1828540.0000 1505942.0000 2395392.0000 3662560.0000 2833746.0000 2672197.0000 2370004.0000 2729734.0000 3627092.0000 2147943.0000 1590755.0000 2402278.0000 3097812.0000 1706557.0000 1741890.0000 3292018.0000 66174.0000 15858.0000 55375.0000 84281.0000 1934511.0000 1495069.0000 2380434.0000 3565252.0000 1802480.0000 1555633.0000 1662525.0000 2665244.0000 1169968.0000 1002208.0000 1480636.0000 3200697.0000 926138.0000 1151887.0000 1806387.0000 L-Aspartic acid 2 902671.0000 1335415.0000 2536176.0000 715121.0000 1271191.0000 974011.0000 2406040.0000 4318614.0000 2816614.0000 3745545.0000 3008859.0000 4254226.0000 4560430.0000 3237891.0000 3139228.0000 3147192.0000 1819295.0000 1283373.0000 1186040.0000 2519482.0000 74203.0000 15296.0000 8049.0000 81410.0000 3099940.0000 1352796.0000 1754714.0000 3980510.0000 1620903.0000 2042526.0000 1782565.0000 4244212.0000 926043.0000 638857.0000 1521097.0000 1323224.0000 383797.0000 800198.0000 1306058.0000 Lauric Acid 932.0000 427.0000 837.0000 729.0000 274.0000 305.0000 847.0000 350.0000 570.0000 447.0000 306.0000 994.0000 238.0000 221.0000 492.0000 226.0000 785.0000 812.0000 691.0000 863.0000 819.0000 464.0000 711.0000 1038.0000 571.0000 703.0000 355.0000 730.0000 284.0000 1607.0000 881.0000 618.0000 620.0000 417.0000 125.0000 310.0000 L-Glutamic acid 3492473.0000 2756564.0000 4500202.0000 1154886.0000 2519674.0000 2292873.0000 3485711.0000 1328408.0000 3328740.0000 6997596.0000 4099115.0000 4833679.0000 1256006.0000 6692964.0000 5518034.0000 5243758.0000 4165381.0000 3498998.0000 1869652.0000 833344.0000 18616.0000 3480.0000 8222343.0000 4911437.0000 3581442.0000 108928.0000 3950966.0000 4620104.0000 4596160.0000 3220058.0000 3646471.0000 1918603.0000 3185518.0000 60539.0000 1925369.0000 1993895.0000 3524550.0000 Linoleic acid L-Isoleucine 1 61253.0000 177124.0000 204795.0000 257671.0000 149659.0000 176113.0000 225819.0000 800152.0000 212709.0000 115646.0000 201526.0000 260377.0000 451341.0000 130354.0000 174375.0000 214962.0000 245586.0000 140026.0000 210884.0000 325838.0000 454787.0000 164434.0000 270719.0000 527680.0000 155565.0000 120514.0000 164573.0000 563566.0000 166782.0000 253208.0000 181493.0000 456470.0000 46522.0000 156012.0000 200761.0000 455742.0000 72257.0000 159969.0000 86831.0000 6060.0000 L-Isoleucine 2 143314.0000 379273.0000 460451.0000 416445.0000 319632.0000 345715.0000 423070.0000 1096488.0000 379494.0000 302850.0000 478674.0000 680411.0000 794172.0000 321700.0000 471054.0000 443427.0000 436026.0000 325161.0000 344347.0000 420861.0000 1375830.0000 390324.0000 445749.0000 726802.0000 281184.0000 279108.0000 284575.0000 630738.0000 310340.0000 541311.0000 328449.0000 873785.0000 109602.0000 327852.0000 430262.0000 388453.0000 115965.0000 288398.0000 161569.0000 20902.0000 L-Kynurenine L-Lactic acid 48737.0000 43476.0000 53173.0000 58666.0000 45586.0000 983.0000 L-Leucine 1 5366644.0000 11159626.0000 12099977.0000 12800418.0000 10130479.0000 10587158.0000 12290828.0000 8805440.0000 12309291.0000 9513452.0000 12565708.0000 13890651.0000 8512800.0000 10599337.0000 11667724.0000 12558403.0000 13323706.0000 10248153.0000 12252397.0000 13484583.0000 7538586.0000 11560539.0000 13498236.0000 8009799.0000 11502585.0000 8776226.0000 10297735.0000 8494026.0000 10339509.0000 13379370.0000 11874861.0000 7765720.0000 4038508.0000 10294226.0000 11976971.0000 7156069.0000 6733636.0000 9816820.0000 7734006.0000 514391.0000 L-Leucine 2 10128028.0000 10752410.0000 10927122.0000 11865036.0000 10968109.0000 11740560.0000 10537744.0000 7950328.0000 11081417.0000 11858747.0000 4422146.0000 11846262.0000 3829487.0000 10103535.0000 11183330.0000 11174517.0000 6870991.0000 7830641.0000 10916940.0000 11578166.0000 6090296.0000 6371644.0000 7648967.0000 7910173.0000 10391307.0000 11986367.0000 11815213.0000 6125190.0000 9506330.0000 10787336.0000 10499333.0000 6566284.0000 8650060.0000 10505171.0000 10042889.0000 8099899.0000 8958155.0000 10745888.0000 10083042.0000 1882508.0000 L-Lysine 1 12010.0000 15270.0000 21581.0000 14266.0000 69195.0000 15571.0000 21415.0000 139532.0000 93642.0000 16427.0000 15798.0000 20356.0000 36415.0000 29864.0000 9956.0000 24223.0000 50623.0000 16064.0000 17751.0000 33395.0000 955.0000 1752.0000 8285.0000 7064.0000 12334.0000 160301.0000 201976.0000 19742.0000 26537.0000 95969.0000 8488.0000 5280.0000 7479.0000 122449.0000 20027.0000 18666.0000 40550.0000 L-Lysine 2 1267400.0000 903331.0000 1545090.0000 778301.0000 1685331.0000 1500174.0000 1855397.0000 1747760.0000 1226098.0000 1348834.0000 970894.0000 1112157.0000 1148830.0000 2063814.0000 1295778.0000 1529237.0000 2316310.0000 1443066.0000 1215855.0000 1697438.0000 9490.0000 537.0000 809668.0000 524346.0000 657083.0000 152873.0000 1213873.0000 1383337.0000 1755772.0000 1748846.0000 526518.0000 323236.0000 523429.0000 231998.0000 2211565.0000 1604601.0000 2951755.0000 L-Methionine 1 7642.0000 15438.0000 25314.0000 20105.0000 24018.0000 20943.0000 29945.0000 123360.0000 40362.0000 18572.0000 28885.0000 29243.0000 69006.0000 34824.0000 32441.0000 45013.0000 25044.0000 17036.0000 17498.0000 31193.0000 45997.0000 13836.0000 13813.0000 47616.0000 13736.0000 10320.0000 14295.0000 76752.0000 19964.0000 36654.0000 32910.0000 83822.0000 6353.0000 13225.0000 16359.0000 42936.0000 19192.0000 20797.0000 22833.0000 110.0000 L-Methionine 2 22651.0000 50145.0000 71559.0000 45781.0000 35263.0000 47677.0000 84549.0000 251925.0000 115133.0000 83372.0000 108200.0000 172994.0000 224484.0000 177392.0000 177637.0000 158873.0000 61368.0000 37269.0000 39828.0000 63211.0000 84587.0000 24686.0000 2630.0000 71310.0000 68647.0000 33097.0000 27406.0000 156264.0000 66496.0000 142865.0000 94873.0000 356563.0000 18795.0000 35269.0000 51341.0000 54563.0000 24733.0000 43989.0000 55901.0000 L-Phenylalanine 1 39549.0000 98092.0000 113645.0000 113543.0000 120275.0000 117006.0000 118703.0000 189141.0000 127085.0000 82347.0000 109688.0000 113319.0000 142351.0000 80932.0000 82540.0000 106302.0000 131072.0000 82397.0000 101490.0000 150130.0000 94452.0000 10945.0000 66744.0000 133515.0000 62111.0000 85446.0000 103152.0000 146293.0000 145542.0000 120621.0000 108749.0000 136828.0000 28394.0000 73653.0000 88009.0000 204002.0000 57830.0000 124333.0000 82808.0000 240.0000 L-Phenylalanine 2 13848.0000 36291.0000 57150.0000 23904.0000 20529.0000 32563.0000 62329.0000 178074.0000 52514.0000 64186.0000 75356.0000 122597.0000 141196.0000 75403.0000 90299.0000 95811.0000 44920.0000 28022.0000 34201.0000 70793.0000 49962.0000 6885.0000 35424.0000 54548.0000 40758.0000 35169.0000 72658.0000 58222.0000 103173.0000 64851.0000 190092.0000 14897.0000 24525.0000 41924.0000 22791.0000 14255.0000 31138.0000 24028.0000 L-Proline 1 144069.0000 300370.0000 487866.0000 212681.0000 332323.0000 295386.0000 508225.0000 240852.0000 531003.0000 532303.0000 499743.0000 492936.0000 458826.0000 532865.0000 452420.0000 501516.0000 390774.0000 230732.0000 339251.0000 538448.0000 525602.0000 295562.0000 526244.0000 305431.0000 455624.0000 430588.0000 354875.0000 46565.0000 52876.0000 100398.0000 222187.0000 400398.0000 107097.0000 220719.0000 168638.0000 207.0000 L-Proline 2 339762.0000 575429.0000 882891.0000 398853.0000 617707.0000 508250.0000 691232.0000 1546661.0000 811519.0000 1075893.0000 874837.0000 1191303.0000 1154027.0000 975345.0000 900994.0000 929853.0000 614757.0000 439314.0000 411145.0000 677255.0000 180509.0000 45219.0000 121746.0000 163105.0000 778438.0000 614332.0000 497419.0000 1384337.0000 668470.0000 736536.0000 551595.0000 1265969.0000 199986.0000 299594.0000 457695.0000 872228.0000 187358.0000 353034.0000 293983.0000 7651.0000 L-Serine 1 199191.0000 259609.0000 424321.0000 235261.0000 399798.0000 243637.0000 385141.0000 879283.0000 481327.0000 402524.0000 331173.0000 439603.0000 633392.0000 418232.0000 279734.0000 420487.0000 463265.0000 266419.0000 295123.0000 613538.0000 98456.0000 19920.0000 104406.0000 95037.0000 344942.0000 217902.0000 341057.0000 570233.0000 482095.0000 388079.0000 409977.0000 819441.0000 196765.0000 182563.0000 266350.0000 536895.0000 263270.0000 322575.0000 464248.0000 L-Serine 2 230623.0000 287406.0000 495111.0000 215127.0000 253772.0000 287039.0000 497591.0000 806352.0000 502154.0000 526880.0000 529710.0000 824201.0000 780000.0000 545936.0000 547064.0000 638712.0000 531437.0000 335554.0000 344517.0000 525769.0000 167269.0000 30635.0000 36452.0000 135578.0000 464732.0000 281495.0000 333183.0000 627958.0000 563813.0000 677029.0000 551056.0000 1070777.0000 219945.0000 215376.0000 342596.0000 412178.0000 244888.0000 347368.0000 410117.0000 L-Threonine 1 363691.0000 380514.0000 523994.0000 338585.0000 529725.0000 424791.0000 516126.0000 1009478.0000 858143.0000 826302.0000 677598.0000 773125.0000 1122547.0000 726356.0000 506544.0000 700165.0000 874630.0000 468606.0000 507687.0000 1142089.0000 116218.0000 34682.0000 95475.0000 100756.0000 661761.0000 480212.0000 698341.0000 744532.0000 738060.0000 536146.0000 549454.0000 1068015.0000 284414.0000 266366.0000 343208.0000 780983.0000 445208.0000 483349.0000 596270.0000 L-Threonine 2 73390.0000 78938.0000 128914.0000 58247.0000 84533.0000 77136.0000 108446.0000 218383.0000 157093.0000 191717.0000 172120.0000 243031.0000 253618.0000 175762.0000 151215.0000 177392.0000 134822.0000 91725.0000 84812.0000 143550.0000 30252.0000 6441.0000 8742.0000 25285.0000 147342.0000 103914.0000 111983.0000 313508.0000 136214.0000 149620.0000 127891.0000 299355.0000 59166.0000 53117.0000 85675.0000 140104.0000 59866.0000 80566.0000 105801.0000 L-Tryptophan 3125.0000 4919.0000 7495.0000 3249.0000 7286.0000 5168.0000 10503.0000 46535.0000 6990.0000 4384.0000 8166.0000 23934.0000 16705.0000 11109.0000 12030.0000 17338.0000 2592.0000 2546.0000 3453.0000 7027.0000 350.0000 947.0000 6164.0000 2518.0000 4361.0000 1509.0000 8980.0000 23279.0000 9847.0000 57940.0000 483.0000 1817.0000 4211.0000 2508.0000 3067.0000 9915.0000 13346.0000 L-Tyrosine 1 8061.0000 21622.0000 26250.0000 27804.0000 25269.0000 19475.0000 23731.0000 124593.0000 70174.0000 35983.0000 36573.0000 49874.0000 64462.0000 45591.0000 24814.0000 57328.0000 38323.0000 18462.0000 24347.0000 43103.0000 22241.0000 42546.0000 60483.0000 90044.0000 20757.0000 19768.0000 27279.0000 244102.0000 76044.0000 45248.0000 49086.0000 134445.0000 5875.0000 15520.0000 19592.0000 144038.0000 9723.0000 20147.0000 17548.0000 L-Tyrosine 2 7322.0000 16050.0000 19430.0000 14681.0000 16290.0000 17677.0000 21492.0000 30392.0000 25153.0000 22596.0000 24334.0000 32393.0000 32561.0000 21411.0000 26448.0000 30467.0000 26073.0000 16212.0000 18515.0000 28025.0000 9829.0000 50.0000 16491.0000 16307.0000 18928.0000 10945.0000 22820.0000 28333.0000 23975.0000 37706.0000 5716.0000 11780.0000 16611.0000 11822.0000 10692.0000 19733.0000 15391.0000 L-Valine 396427.0000 716230.0000 1033350.0000 672470.0000 817602.0000 817115.0000 1140431.0000 1972998.0000 1190807.0000 901618.0000 1249024.0000 1686806.0000 1784278.0000 1282077.0000 1299424.0000 1493687.0000 1233643.0000 899520.0000 1046254.0000 1392960.0000 732629.0000 250682.0000 399076.0000 454211.0000 1379926.0000 1026169.0000 1238540.0000 2438032.0000 1436329.0000 2153705.0000 1755185.0000 3703994.0000 524565.0000 800535.0000 1016256.0000 1219380.0000 1037327.0000 1341502.0000 1589890.0000 66682.0000 L-Valine 1 94547.0000 167530.0000 226252.0000 136759.0000 189443.0000 188819.0000 255386.0000 1041822.0000 264760.0000 202617.0000 224518.0000 289220.0000 622810.0000 257339.0000 190921.0000 316691.0000 325515.0000 154807.0000 250650.0000 585480.0000 189323.0000 42324.0000 125524.0000 307118.0000 424762.0000 249377.0000 335298.0000 1214322.0000 368069.0000 408261.0000 455660.0000 1056351.0000 117519.0000 159659.0000 229140.0000 622003.0000 316474.0000 343872.0000 411369.0000 11920.0000 Malonic acid Mannitol 61055.0000 150557.0000 75188.0000 36705.0000 47372.0000 55730.0000 45178.0000 41584.0000 73703.0000 112483.0000 86516.0000 105706.0000 87395.0000 109371.0000 123632.0000 75665.0000 139406.0000 87439.0000 85510.0000 120101.0000 104628.0000 83374.0000 145075.0000 9661.0000 175934.0000 172752.0000 127036.0000 169064.0000 88849.0000 84867.0000 63972.0000 83613.0000 100290.0000 95384.0000 124450.0000 145593.0000 60196.0000 48321.0000 73892.0000 myo-Inositol 309062.0000 336225.0000 433941.0000 273343.0000 357471.0000 239105.0000 358669.0000 584363.0000 585370.0000 684211.0000 574334.0000 770716.0000 866223.0000 600315.0000 483071.0000 599102.0000 688743.0000 405357.0000 396790.0000 617297.0000 266768.0000 56122.0000 148284.0000 198260.0000 764330.0000 424683.0000 479815.0000 1086855.0000 703029.0000 525960.0000 494102.0000 851436.0000 272183.0000 237915.0000 327767.0000 482647.0000 257223.0000 270792.0000 327950.0000 12846.0000 Myristic acid 29462.0000 20901.0000 28904.0000 24890.0000 57617.0000 56470.0000 25720.0000 98846.0000 35173.0000 31673.0000 28095.0000 27456.0000 55760.0000 25169.0000 14925.0000 24227.0000 30720.0000 21481.0000 23155.0000 48243.0000 68119.0000 18175.0000 41132.0000 50981.0000 26463.0000 39841.0000 61356.0000 56098.0000 29855.0000 22194.0000 92941.0000 30358.0000 17640.0000 23652.0000 50933.0000 54775.0000 66968.0000 40324.0000 Myristic Acid d27 278.0000 N-acetyl-L-aspartic acid 98.0000 Nicotinamide 544.0000 393.0000 125.0000 298.0000 81.0000 Nitrous Oxide 376001.0000 272812.0000 312712.0000 289225.0000 550243.0000 649769.0000 306232.0000 662370.0000 317790.0000 427652.0000 274339.0000 287391.0000 380610.0000 259372.0000 227391.0000 272857.0000 322150.0000 192430.0000 194666.0000 244001.0000 428076.0000 230530.0000 233960.0000 265908.0000 603791.0000 285939.0000 327624.0000 331317.0000 536989.0000 293341.0000 289121.0000 418227.0000 350223.0000 266831.0000 291499.0000 375547.0000 464435.0000 725703.0000 274733.0000 14662.0000 Nonanoic acid 36932.0000 25825.0000 23362.0000 18387.0000 39840.0000 38021.0000 27215.0000 54966.0000 24815.0000 34592.0000 19036.0000 20718.0000 42309.0000 33703.0000 21521.0000 20672.0000 33064.0000 20375.0000 38013.0000 52710.0000 48855.0000 16724.0000 20215.0000 41142.0000 41877.0000 25496.0000 31208.0000 29861.0000 49184.0000 43996.0000 22775.0000 53773.0000 37494.0000 28329.0000 23111.0000 48774.0000 49018.0000 37172.0000 30646.0000 Oleic acid 9661.0000 7351.0000 9364.0000 6248.0000 9064.0000 14209.0000 12436.0000 20222.0000 12839.0000 11196.0000 11985.0000 9991.0000 15782.0000 9087.0000 7018.0000 9533.0000 7595.0000 7196.0000 9483.0000 15395.0000 32017.0000 3414.0000 2840.0000 9881.0000 15193.0000 12047.0000 14479.0000 16733.0000 9462.0000 10728.0000 9105.0000 17235.0000 13114.0000 5382.0000 9487.0000 11110.0000 14374.0000 13574.0000 14641.0000 O-Phosphoethanolamine 234.0000 197.0000 216.0000 415.0000 459.0000 224.0000 174.0000 584.0000 249.0000 Ornithine 26434.0000 18801.0000 41548.0000 17954.0000 34274.0000 52956.0000 79319.0000 25238.0000 47082.0000 69589.0000 41390.0000 58842.0000 37783.0000 104853.0000 92078.0000 96359.0000 35347.0000 40631.0000 38985.0000 39748.0000 2152.0000 29657.0000 16368.0000 19883.0000 33013.0000 77228.0000 79848.0000 41950.0000 8535.0000 5479.0000 11286.0000 87423.0000 56824.0000 77542.0000 211.0000 Oxalic acid 20007.0000 45890.0000 30072.0000 52568.0000 17485.0000 45125.0000 54384.0000 30153.0000 63663.0000 27549.0000 55231.0000 65585.0000 33535.0000 24367.0000 46979.0000 76821.0000 61719.0000 46892.0000 64497.0000 47208.0000 124336.0000 43400.0000 65344.0000 45926.0000 55677.0000 69742.0000 67214.0000 27967.0000 44137.0000 60137.0000 65681.0000 33898.0000 29452.0000 54647.0000 50041.0000 47248.0000 45196.0000 46144.0000 47432.0000 1284.0000 Palmitic acid 699591.0000 437643.0000 1966503.0000 426358.0000 3278778.0000 2846544.0000 1554423.0000 3328608.0000 993525.0000 921325.0000 1361694.0000 1012141.0000 1214383.0000 1712388.0000 546974.0000 802459.0000 802542.0000 539541.0000 1057112.0000 1372537.0000 1261520.0000 190087.0000 217422.0000 543159.0000 2301214.0000 1244636.0000 1725874.0000 2842198.0000 2963357.0000 1971333.0000 983623.0000 3524997.0000 902680.0000 659148.0000 1794360.0000 1732225.0000 3539560.0000 3069147.0000 4365441.0000 Palmitoleic acid 37198.0000 22145.0000 25417.0000 30415.0000 30815.0000 43070.0000 35289.0000 52929.0000 33427.0000 30453.0000 35336.0000 24086.0000 44267.0000 24884.0000 21776.0000 28925.0000 23047.0000 20345.0000 23874.0000 54958.0000 122318.0000 15015.0000 15126.0000 42433.0000 36959.0000 39054.0000 40239.0000 48531.0000 27911.0000 32915.0000 29536.0000 45861.0000 43210.0000 22039.0000 30079.0000 29567.0000 42070.0000 35680.0000 38373.0000 303.0000 Pantothenic acid 184.0000 210.0000 403.0000 Phosphate 540556.0000 1255378.0000 1687165.0000 1172350.0000 1369297.0000 1023666.0000 1486015.0000 2666654.0000 1929281.0000 1131110.0000 1228959.0000 1667061.0000 2033920.0000 1332505.0000 1213435.0000 1461856.0000 2003463.0000 1112730.0000 1208965.0000 2334886.0000 934849.0000 206650.0000 680256.0000 933578.0000 894610.0000 886212.0000 1234216.0000 2359925.0000 1928376.0000 1533414.0000 1294889.0000 2452725.0000 520979.0000 1077795.0000 1618939.0000 3071109.0000 736708.0000 1152038.0000 1320684.0000 Phosphoenolpyruvate Putrescine 532552.0000 178198.0000 544588.0000 164822.0000 151902.0000 38105.0000 53498.0000 70743.0000 27935.0000 885837.0000 431661.0000 450180.0000 806279.0000 158688.0000 31392.0000 52855.0000 858472.0000 520546.0000 408837.0000 728172.0000 2231.0000 1201.0000 678.0000 808.0000 2153504.0000 1270917.0000 1669907.0000 878917.0000 318535.0000 84633.0000 145101.0000 89343.0000 1119174.0000 353281.0000 613193.0000 200843.0000 270283.0000 243260.0000 342372.0000 8747.0000 Pyroglutamic acid 9036022.0000 10816980.0000 13241842.0000 9524331.0000 11321874.0000 8808074.0000 12243082.0000 9370197.0000 7262124.0000 14247434.0000 14700518.0000 7596372.0000 10332917.0000 15100528.0000 13855377.0000 15399021.0000 7564903.0000 12604975.0000 13676566.0000 7795729.0000 699950.0000 182162.0000 341117.0000 696661.0000 15390103.0000 13316969.0000 8062983.0000 11764136.0000 7551098.0000 15274705.0000 14594939.0000 11701354.0000 10280697.0000 8783031.0000 12054981.0000 8502830.0000 7991402.0000 9331420.0000 12143418.0000 Pyrophosphate 2103.0000 5801.0000 8934.0000 5979.0000 21280.0000 6190.0000 5325.0000 29528.0000 23017.0000 8518.0000 7980.0000 9151.0000 9176.0000 10206.0000 5064.0000 7350.0000 5833.0000 6735.0000 2067.0000 3217.0000 2536.0000 23938.0000 12575.0000 3182.0000 5146.0000 5329.0000 49117.0000 30237.0000 5568.0000 7174.0000 26563.0000 1861.0000 2329.0000 4131.0000 32771.0000 4760.0000 9353.0000 19142.0000 Pyrrolidonecarboxylic acid 1733.0000 1441.0000 1748.0000 549.0000 1601.0000 1486.0000 288.0000 584.0000 846.0000 727.0000 236.0000 395.0000 517.0000 1735.0000 1338.0000 1585.0000 1481.0000 70.0000 45.0000 4724.0000 2063.0000 2032.0000 3803.0000 1353.0000 1455.0000 659.0000 1330.0000 5005.0000 3580.0000 3727.0000 3552.0000 2329.0000 2595.0000 3717.0000 Pyruvic acid 82456.0000 145196.0000 249120.0000 104854.0000 210906.0000 124561.0000 252832.0000 619146.0000 332549.0000 181729.0000 168046.0000 207707.0000 320742.0000 321376.0000 202026.0000 279310.0000 84850.0000 59814.0000 81903.0000 142615.0000 6287.0000 3344.0000 5744.0000 20278.0000 154284.0000 85078.0000 132872.0000 406262.0000 311452.0000 284502.0000 329866.0000 625222.0000 104521.0000 100139.0000 161770.0000 321563.0000 151435.0000 173679.0000 276801.0000 11306.0000 Ribitol 5955.0000 7767.0000 9343.0000 4830.0000 6604.0000 6179.0000 7979.0000 12480.0000 7099.0000 9342.0000 6796.0000 8337.0000 9386.0000 7564.0000 6529.0000 6548.0000 10002.0000 7467.0000 7481.0000 14656.0000 3900.0000 883.0000 1693.0000 2589.0000 13240.0000 9418.0000 11996.0000 16842.0000 9921.0000 9064.0000 8023.0000 15579.0000 14227.0000 10178.0000 15739.0000 23420.0000 8687.0000 10362.0000 10090.0000 427.0000 Sarcosine 3995.0000 9156.0000 8372.0000 11241.0000 3942.0000 9503.0000 11753.0000 10926.0000 15167.0000 7010.0000 12422.0000 18034.0000 13627.0000 6082.0000 10390.0000 15122.0000 11526.0000 8572.0000 14390.0000 12025.0000 21785.0000 7376.0000 12964.0000 6317.0000 9623.0000 11671.0000 15667.0000 17227.0000 7321.0000 11116.0000 14091.0000 13878.0000 5140.0000 10280.0000 11175.0000 12407.0000 7160.0000 8981.0000 10084.0000 348.0000 Sedoheptulose 7-phosphate 2577.0000 3612.0000 7369.0000 2688.0000 5757.0000 3994.0000 8361.0000 19836.0000 6166.0000 5253.0000 4919.0000 6579.0000 10192.0000 4795.0000 4184.0000 6187.0000 6728.0000 4025.0000 4657.0000 9286.0000 4642.0000 2359.0000 5256.0000 11135.0000 5824.0000 6513.0000 7261.0000 14768.0000 3710.0000 3022.0000 4687.0000 9749.0000 4080.0000 4289.0000 8734.0000 Serotonin 29.0000 Sorbitol 61055.0000 150557.0000 75188.0000 36705.0000 47372.0000 55730.0000 45178.0000 41584.0000 73703.0000 112483.0000 86516.0000 105706.0000 87395.0000 109371.0000 123632.0000 75665.0000 139406.0000 87439.0000 85510.0000 120101.0000 104628.0000 83374.0000 145075.0000 9661.0000 175934.0000 172752.0000 127036.0000 169064.0000 88849.0000 84867.0000 63972.0000 83613.0000 100290.0000 95384.0000 124450.0000 145593.0000 60196.0000 48321.0000 73892.0000 Spermidine 2368.0000 158.0000 7245.0000 318.0000 2837.0000 280.0000 2482.0000 1131.0000 382.0000 841.0000 419.0000 4016.0000 1111.0000 4080.0000 3235.0000 2595.0000 923.0000 141.0000 125.0000 2279.0000 7809.0000 49.0000 400.0000 702.0000 903.0000 9337.0000 1077.0000 3645.0000 996.0000 1320.0000 535.0000 919.0000 Stearic acid 585844.0000 173712.0000 996180.0000 227187.0000 2086888.0000 2560466.0000 900505.0000 3151444.0000 882936.0000 917348.0000 761034.0000 565108.0000 1106522.0000 551588.0000 284095.0000 508599.0000 498152.0000 404108.0000 663484.0000 1213922.0000 354758.0000 74569.0000 102151.0000 242859.0000 2763948.0000 780333.0000 1377364.0000 1395256.0000 2070388.0000 903997.0000 466302.0000 3455705.0000 698998.0000 347614.0000 1012493.0000 1249255.0000 2549000.0000 2786033.0000 2089218.0000 31.0000 Succinic acid 13089.0000 16915.0000 21631.0000 14924.0000 25122.0000 17414.0000 22859.0000 33671.0000 22122.0000 18641.0000 13750.0000 16149.0000 17266.0000 19870.0000 16623.0000 21710.0000 39058.0000 16851.0000 26475.0000 35039.0000 36250.0000 4406.0000 13816.0000 12639.0000 20505.0000 13522.0000 18479.0000 25856.0000 32196.0000 20465.0000 20452.0000 33895.0000 27761.0000 24014.0000 36748.0000 68964.0000 24663.0000 27655.0000 31323.0000 Succinylacetone 771.0000 173.0000 48.0000 334.0000 19.0000 403.0000 3534.0000 1044.0000 605.0000 1074.0000 1056.0000 469.0000 1384.0000 1031.0000 659.0000 560.0000 403.0000 1069.0000 577.0000 399.0000 243.0000 801.0000 553.0000 922.0000 558.0000 Sugar Alcohol-phosphate 536.0000 585.0000 1095.0000 743.0000 793.0000 854.0000 323.0000 858.0000 723.0000 1390.0000 1583.0000 2030.0000 3191.0000 470.0000 326.0000 385.0000 529.0000 90.0000 840.0000 672.0000 2209.0000 721.0000 141.0000 537.0000 973.0000 64.0000 394.0000 956.0000 63.0000 1454.0000 274.0000 Taurine Threonic acid 676.0000 1686.0000 2108.0000 1056.0000 939.0000 1125.0000 2507.0000 1107.0000 3632.0000 1526.0000 1902.0000 3064.0000 713.0000 2894.0000 3387.0000 3896.0000 2086.0000 1326.0000 2134.0000 870.0000 1122.0000 572.0000 753.0000 1886.0000 434.0000 1504.0000 787.0000 2249.0000 3845.0000 2812.0000 1470.0000 1046.0000 1260.0000 2394.0000 993.0000 1197.0000 1220.0000 1125.0000 Thymine 491.0000 190.0000 Uracil 58962.0000 162725.0000 189125.0000 177087.0000 164787.0000 165912.0000 188564.0000 437548.0000 198296.0000 168180.0000 194946.0000 266380.0000 327985.0000 120559.0000 169909.0000 197517.0000 189403.0000 124344.0000 151337.0000 298676.0000 345797.0000 47622.0000 169011.0000 233223.0000 119230.0000 145393.0000 177844.0000 255112.0000 230700.0000 220973.0000 149209.0000 355251.0000 48809.0000 136965.0000 185294.0000 338510.0000 54328.0000 185181.0000 74882.0000 Urea 12424.0000 15579.0000 23160.0000 11506.0000 7455.0000 10592.0000 15235.0000 17364.0000 14482.0000 27988.0000 38399.0000 47586.0000 66866.0000 22671.0000 22178.0000 27112.0000 22384.0000 11221.0000 27345.0000 21487.0000 24182.0000 661.0000 578.0000 15205.0000 113649.0000 35527.0000 36332.0000 124223.0000 18824.0000 30242.0000 29718.0000 47276.0000 18854.0000 19668.0000 32620.0000 37702.0000 12472.0000 12807.0000 15628.0000 Uric acid Uridine 523.0000 99.0000 2525.0000 1855.0000 127.0000 186.0000 334.0000 403.0000 86.0000 589.0000 1002.0000 146.0000 111.0000 792.0000 109.0000 Xanthine Xanthurenic acid Zymosterol MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name pubchem_id inchi_key kegg_id other_id other_id_type ri ri_type moverz_quant 1-Palmitoylglycerol 1-Steroylglycerol 2'3'-Bisphosphoglycerate 2-Aminoadipic acid 2-Hydroxybenzoic acid 2-Hydroxybutyric acid 2-Hydroxyglutaric acid 2-Ketoglutarate 2-Monopalmitoylglycerol 2-Steroylglycerol 3-Hydroxybutyrate 3-Phosphoglyceric acid 4-Hydroxyproline 1 4-Hydroxyproline 2 5-Hydroxytryptophan Adenine Adenosine Adenosine 3'-monophosphate Adenosine 5'-monophosphate Adipic acid Allantoin Arachidic acid Arachidonic acid Ascorbic acid Benzoic acid Beta-Alanine Beta-Amino Isobutyric acid Beta-Lactate Beta-Sitosterol C20:3 A C20:3 B Campesterol Capric acid Cholesterol cis-Aconitic acid Citric acid Creatinine Cystathionine d4-succinate Dehydroascorbic acid D-Fructose 1 D-Fructose 2 D-Glucose 1 D-Glucose 2 DHAP Diethyl Phthalate Disaccharide 1 Disaccharide 2 D-Malic acid D-Mannose D-Threitol Elaidic acid Ergosterol Ethanolamine 1 Ethanolamine 2 Fructose-6-phosphate Fumaric acid GABA Galactosamine Gluconic acid Glucose 6-phosphate Glutamic acid Glutamine Glycerol Glycerol 3-phosphate Glycine Glycolic acid Glyoxylic acid Heptadecanoic acid Hypotaurine Hypoxanthine Inosine Inositol phosphate Isocitric acid L-Alanine 1 L-Alanine 2 Lanthionine L-Asparagine L-Aspartic acid 1 L-Aspartic acid 2 Lauric Acid L-Glutamic acid Linoleic acid L-Isoleucine 1 L-Isoleucine 2 L-Kynurenine L-Lactic acid L-Leucine 1 L-Leucine 2 L-Lysine 1 L-Lysine 2 L-Methionine 1 L-Methionine 2 L-Phenylalanine 1 L-Phenylalanine 2 L-Proline 1 L-Proline 2 L-Serine 1 L-Serine 2 L-Threonine 1 L-Threonine 2 L-Tryptophan L-Tyrosine 1 L-Tyrosine 2 L-Valine L-Valine 1 Malonic acid Mannitol myo-Inositol Myristic acid Myristic Acid d27 N-acetyl-L-aspartic acid Nicotinamide Nitrous Oxide Nonanoic acid Oleic acid O-Phosphoethanolamine Ornithine Oxalic acid Palmitic acid Palmitoleic acid Pantothenic acid Phosphate Phosphoenolpyruvate Putrescine Pyroglutamic acid Pyrophosphate Pyrrolidonecarboxylic acid Pyruvic acid Ribitol Sarcosine Sedoheptulose 7-phosphate Serotonin Sorbitol Spermidine Stearic acid Succinic acid Succinylacetone Sugar Alcohol-phosphate Taurine Threonic acid Thymine Uracil Urea Uric acid Uridine Xanthine Xanthurenic acid Zymosterol METABOLITES_END #END