#METABOLOMICS WORKBENCH mtakahama_20230123_063017 DATATRACK_ID:3697 STUDY_ID:ST002455 ANALYSIS_ID:AN004005 PROJECT_ID:PR001583 VERSION 1 CREATED_ON January 26, 2023, 10:55 am #PROJECT PR:PROJECT_TITLE Organism-Wide Analysis of Sepsis Reveals Mechanisms of Systemic Inflammation PR:PROJECT_TYPE lipidomics analysis PR:PROJECT_SUMMARY Phospholipase A2 group V (PLA2G5) is a secretory and Ca2+-dependent lipolytic PR:PROJECT_SUMMARY enzyme and is inducible during several pathologic conditions. However, it has PR:PROJECT_SUMMARY been unknown how PLA2G5 plays a role in sepsis. To study the role of PLA2G5 in PR:PROJECT_SUMMARY sepsis, we performed lipidomics analysis of plasma and tissues from LPS-injected PR:PROJECT_SUMMARY mice with or without PLA2G5 blockade. Here, we showed that PLA2G5 is involved in PR:PROJECT_SUMMARY the production of fatty acids such as oleic acid and linoleic acid, PR:PROJECT_SUMMARY lysophospholipids such as lysophosphatidic acid, lysophosphatidylcholine, PR:PROJECT_SUMMARY lysophatidylethanolamine, and lysophosphatidylserine species, and metabolites PR:PROJECT_SUMMARY derived from polyunsaturated fatty acids such as arachidonic acid, PR:PROJECT_SUMMARY eicosapentaenoic acid, docosahexaenoic acid, and linoleic acids during sepsis. PR:PROJECT_SUMMARY Thus, PLA2G5 regulates selective lipid pathways during sepsis. PR:INSTITUTE University of Chicago PR:DEPARTMENT Pritzker School of Molecular Engineering PR:LABORATORY Chevrier lab PR:LAST_NAME Takahama PR:FIRST_NAME Michihiro PR:ADDRESS 900 E 57th St,, Chicago, Illinois, 60637, USA PR:EMAIL mtakahama@uchicago.edu PR:PHONE 7732302766 #STUDY ST:STUDY_TITLE Organism-Wide Analysis of Sepsis Reveals Mechanisms of Systemic Inflammation ST:STUDY_TYPE lipidomics analysis ST:STUDY_SUMMARY Phospholipase A2 group V (PLA2G5) is a secretory and Ca2+-dependent lipolytic ST:STUDY_SUMMARY enzyme and is inducible during several pathologic conditions. However, it has ST:STUDY_SUMMARY been unknown how PLA2G5 plays a role in sepsis. To study the role of PLA2G5 in ST:STUDY_SUMMARY sepsis, we performed lipidomics analysis of plasma and tissues from LPS-injected ST:STUDY_SUMMARY mice with or without PLA2G5 blockade. Here, we showed that PLA2G5 is involved in ST:STUDY_SUMMARY the production of fatty acids such as oleic acid and linoleic acid, ST:STUDY_SUMMARY lysophospholipids such as lysophosphatidic acid, lysophosphatidylcholine, ST:STUDY_SUMMARY lysophatidylethanolamine, and lysophosphatidylserine species, and metabolites ST:STUDY_SUMMARY derived from polyunsaturated fatty acids such as arachidonic acid, ST:STUDY_SUMMARY eicosapentaenoic acid, docosahexaenoic acid, and linoleic acids during sepsis. ST:STUDY_SUMMARY Thus, PLA2G5 regulates selective lipid pathways during sepsis. ST:INSTITUTE University of Chicago ST:DEPARTMENT Pritzker School of Molecular Engineering ST:LABORATORY Chevrier lab ST:LAST_NAME Takahama ST:FIRST_NAME Michihiro ST:ADDRESS 900 E 57th St,, Chicago, Illinois, 60637, USA ST:EMAIL mtakahama@uchicago.edu ST:PHONE 7732302766 #SUBJECT SU:SUBJECT_TYPE Mammal SU:SUBJECT_SPECIES Mus musculus SU:TAXONOMY_ID 10090 SU:GENOTYPE_STRAIN C57BL/6J SU:AGE_OR_AGE_RANGE 6 weeks SU:GENDER Female SU:ANIMAL_ANIMAL_SUPPLIER JAX #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data SUBJECT_SAMPLE_FACTORS SP1 SP_FFA_1 Genotype:Wild-type | Treatment:LPS Batch=m1; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS SP2 SP_FFA_2 Genotype:Wild-type | Treatment:LPS Batch=m2; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS SP3 SP_FFA_3 Genotype:Wild-type | Treatment:LPS Batch=m3; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS SP4 SP_FFA_4 Genotype:Wild-type | Treatment:LPS Batch=m4; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS SP5 SP_FFA_5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m5; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS SP6 SP_FFA_6 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m6; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS SP7 SP_FFA_7 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m7; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS SP8 SP_FFA_8 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m8; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS SP9 SP_Oxylipin_1 Genotype:Wild-type | Treatment:LPS Batch=m1; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS SP10 SP_Oxylipin_2 Genotype:Wild-type | Treatment:LPS Batch=m2; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS SP11 SP_Oxylipin_3 Genotype:Wild-type | Treatment:LPS Batch=m3; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS SP12 SP_Oxylipin_4 Genotype:Wild-type | Treatment:LPS Batch=m4; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS SP13 SP_Oxylipin_5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m5; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS SP14 SP_Oxylipin_6 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m6; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS SP15 SP_Oxylipin_7 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m7; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS SP16 SP_Oxylipin_8 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m8; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS CO1 CO_FFA_1 Genotype:Wild-type | Treatment:LPS Batch=m1; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS CO2 CO_FFA_2 Genotype:Wild-type | Treatment:LPS Batch=m2; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS CO3 CO_FFA_3 Genotype:Wild-type | Treatment:LPS Batch=m3; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS CO4 CO_FFA_4 Genotype:Wild-type | Treatment:LPS Batch=m4; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS CO5 CO_FFA_5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m5; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS CO6 CO_FFA_6 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m6; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS CO7 CO_FFA_7 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m7; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS CO8 CO_FFA_8 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m8; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS CO9 CO_Oxylipin_1 Genotype:Wild-type | Treatment:LPS Batch=m1; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS CO10 CO_Oxylipin_2 Genotype:Wild-type | Treatment:LPS Batch=m2; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS CO11 CO_Oxylipin_3 Genotype:Wild-type | Treatment:LPS Batch=m3; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS CO12 CO_Oxylipin_4 Genotype:Wild-type | Treatment:LPS Batch=m4; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS CO13 CO_Oxylipin_5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m5; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS CO14 CO_Oxylipin_6 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m6; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS CO15 CO_Oxylipin_7 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m7; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS CO16 CO_Oxylipin_8 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m8; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS BM1 BM_FFA_1 Genotype:Wild-type | Treatment:LPS Batch=m1; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS BM2 BM_FFA_2 Genotype:Wild-type | Treatment:LPS Batch=m2; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS BM3 BM_FFA_3 Genotype:Wild-type | Treatment:LPS Batch=m3; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS BM4 BM_FFA_4 Genotype:Wild-type | Treatment:LPS Batch=m4; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS BM5 BM_FFA_5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m5; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS BM6 BM_FFA_6 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m6; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS BM7 BM_FFA_7 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m7; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS BM8 BM_FFA_8 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m8; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS BM9 BM_Oxylipin_1 Genotype:Wild-type | Treatment:LPS Batch=m1; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS BM10 BM_Oxylipin_2 Genotype:Wild-type | Treatment:LPS Batch=m2; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS BM11 BM_Oxylipin_3 Genotype:Wild-type | Treatment:LPS Batch=m3; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS BM12 BM_Oxylipin_4 Genotype:Wild-type | Treatment:LPS Batch=m4; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS BM13 BM_Oxylipin_5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m5; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS BM14 BM_Oxylipin_6 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m6; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS BM15 BM_Oxylipin_7 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m7; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS BM16 BM_Oxylipin_8 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m8; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS PL1 PL_FFA_1 Genotype:Wild-type | Treatment:LPS Batch=m1; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS PL2 PL_FFA_2 Genotype:Wild-type | Treatment:LPS Batch=m2; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS PL3 PL_FFA_3 Genotype:Wild-type | Treatment:LPS Batch=m3; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS PL4 PL_FFA_4 Genotype:Wild-type | Treatment:LPS Batch=m4; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS PL5 PL_FFA_5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m5; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS PL6 PL_FFA_6 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m6; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS PL7 PL_FFA_7 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m7; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS PL8 PL_FFA_8 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m8; RAW_FILE_NAME=FFA.wiff; RAW_FILE_NAME=FFA.wiff.scan SUBJECT_SAMPLE_FACTORS PL9 PL_Oxylipin_1 Genotype:Wild-type | Treatment:LPS Batch=m1; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS PL10 PL_Oxylipin_2 Genotype:Wild-type | Treatment:LPS Batch=m2; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS PL11 PL_Oxylipin_3 Genotype:Wild-type | Treatment:LPS Batch=m3; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS PL12 PL_Oxylipin_4 Genotype:Wild-type | Treatment:LPS Batch=m4; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS PL13 PL_Oxylipin_5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m5; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS PL14 PL_Oxylipin_6 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m6; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS PL15 PL_Oxylipin_7 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m7; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan SUBJECT_SAMPLE_FACTORS PL16 PL_Oxylipin_8 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Batch=m8; RAW_FILE_NAME=Oxylipin.wiff; RAW_FILE_NAME=Oxylipin.wiff.scan #COLLECTION CO:COLLECTION_SUMMARY C57BL/6J were injected intraperitoneally with 50 µg of anti-PLA2G5 neutralizing CO:COLLECTION_SUMMARY antibodies in 100 µl of PBS 1 hour prior to LPS injection. Twelve hours after CO:COLLECTION_SUMMARY LPS injection, mice were anesthetized with 2,2,2-tribromoethanol (250-500 mg/kg) CO:COLLECTION_SUMMARY and perfused transcardially with PBS containing 10 mM EDTA. Plasma was collected CO:COLLECTION_SUMMARY from blood prior to perfusion and frozen at -80°C. Immediately after perfusion, CO:COLLECTION_SUMMARY colon tissues were extensively washed in PBS and frozen by liquid nitrogen and CO:COLLECTION_SUMMARY kept at -80°C until the following procedures. CO:SAMPLE_TYPE Blood (plasma) CO:STORAGE_CONDITIONS -80℃ #TREATMENT TR:TREATMENT_SUMMARY C57BL/6J were injected intraperitoneally with 50 µg of anti-PLA2G5 neutralizing TR:TREATMENT_SUMMARY antibodies in 100 µl of PBS 1 hour prior to LPS injection. #SAMPLEPREP SP:SAMPLEPREP_SUMMARY Tissues were mechanically homogenized with the Precellys 24 homogenizer (Bertin SP:SAMPLEPREP_SUMMARY Technologies, Montigny-le-Bretonneux, France) in methanol containing internal SP:SAMPLEPREP_SUMMARY standards (500 pmol/sample of d4-labeled EPA, d5-labeled PGE2, LPC with a 17:0 SP:SAMPLEPREP_SUMMARY fatty acyl chain (LPC17:0), and PC with two 14:0 fatty acyl chains SP:SAMPLEPREP_SUMMARY (PE14:0-14:0)) and then incubated overnight at -20°C. For extraction of SP:SAMPLEPREP_SUMMARY phospholipids and lysophospholipids, one-tenth of tissue lysates were added to SP:SAMPLEPREP_SUMMARY 10 volumes of 20 mM Tris-HCl (pH 7.4) and were extracted using the method of SP:SAMPLEPREP_SUMMARY Bligh and Dyer. For extraction of oxygenated fatty acid metabolites, nine-tenths SP:SAMPLEPREP_SUMMARY of the tissue lysates were added to water (final methanol concentration of 10% SP:SAMPLEPREP_SUMMARY (v/v)), and the lipids were extracted using an Oasis HLB cartridge (Waters, SP:SAMPLEPREP_SUMMARY Milford, MA, USA). #CHROMATOGRAPHY CH:CHROMATOGRAPHY_TYPE Reversed phase CH:INSTRUMENT_NAME Shimadzu Nexera X2 CH:COLUMN_NAME Phenomenex Kinetex C18 (150 x 2.1mm,1.7um) CH:SOLVENT_A acetonitrile/methanol/water = 1/1/1 (v/v/v) containing 5 mM phosphoric acid and CH:SOLVENT_A 1 mM ammonium formate CH:SOLVENT_B 2-propanol containing 5 uM phosphoric acid and 1 mM ammonium formate CH:FLOW_GRADIENT linear CH:FLOW_RATE 0.2 mL/min CH:COLUMN_TEMPERATURE 50 #ANALYSIS AN:ANALYSIS_TYPE MS #MS MS:INSTRUMENT_NAME ABI Sciex 4000 QTrap MS:INSTRUMENT_TYPE Triple quadrupole MS:MS_TYPE ESI MS:ION_MODE UNSPECIFIED MS:MS_COMMENTS The samples were applied to a Kinetex C18 column (Kinetex C18, 2.1 x 150 mm, 1.7 MS:MS_COMMENTS µm particle; Phenomenex, Inc., Torrance, CA, USA) connected with ESI-MS/MS on a MS:MS_COMMENTS liquid chromatography (NexeraX2 system; Shimadzu Co., Kyoto, Japan) coupled with MS:MS_COMMENTS a 4000Q-TRAP quadrupole-linear ion trap hybrid mass spectrometer (AB Sciex, MS:MS_COMMENTS Framingham, MA, USA). For analyses of free fatty acids (FFAs), lysophospholipids MS:MS_COMMENTS (LPLs) and phospholipids, the samples were applied to the column and separated MS:MS_COMMENTS by a step gradient with mobile phase A (acetonitrile/methanol/water =1/1/1 MS:MS_COMMENTS (v/v/v) containing 5 mM phosphoric acid and 1 mM ammonium formate) and mobile MS:MS_COMMENTS phase B (2-propanol containing 5 µM phosphoric acid and 1 mM ammonium formate) MS:MS_COMMENTS at a flow rate of 0.2 mL/min at 50°C. For analyses of oxygenated fatty acid MS:MS_COMMENTS metabolites, the samples were applied to the column and separated using a step MS:MS_COMMENTS gradient including mobile phase C (water containing 0.1 % acetic acid) and MS:MS_COMMENTS mobile phase D (acetonitrile/methanol = 4/1 (v/v)) at a flow rate of 0.2 mL/ min MS:MS_COMMENTS at 45°C. Identification of phospholipids, LPLs, FFAs, and oxygenated PUFAs MS:MS_COMMENTS (polyunsaturated fatty acids) metabolites was conducted by multiple reaction MS:MS_COMMENTS monitoring (MRM) transition, and quantification was performed based on the peak MS:MS_COMMENTS area of the MRM transition and the calibration curve obtained with an authentic MS:MS_COMMENTS standard for each compound. #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS intensity MS_METABOLITE_DATA_START Samples SP_FFA_1 SP_FFA_2 SP_FFA_3 SP_FFA_4 SP_FFA_5 SP_FFA_6 SP_FFA_7 SP_FFA_8 SP_Oxylipin_1 SP_Oxylipin_2 SP_Oxylipin_3 SP_Oxylipin_4 SP_Oxylipin_5 SP_Oxylipin_6 SP_Oxylipin_7 SP_Oxylipin_8 CO_FFA_1 CO_FFA_2 CO_FFA_3 CO_FFA_4 CO_FFA_5 CO_FFA_6 CO_FFA_7 CO_FFA_8 CO_Oxylipin_1 CO_Oxylipin_2 CO_Oxylipin_3 CO_Oxylipin_4 CO_Oxylipin_5 CO_Oxylipin_6 CO_Oxylipin_7 CO_Oxylipin_8 BM_FFA_1 BM_FFA_2 BM_FFA_3 BM_FFA_4 BM_FFA_5 BM_FFA_6 BM_FFA_7 BM_FFA_8 BM_Oxylipin_1 BM_Oxylipin_2 BM_Oxylipin_3 BM_Oxylipin_4 BM_Oxylipin_5 BM_Oxylipin_6 BM_Oxylipin_7 BM_Oxylipin_8 PL_FFA_1 PL_FFA_2 PL_FFA_3 PL_FFA_4 PL_FFA_5 PL_FFA_6 PL_FFA_7 PL_FFA_8 PL_Oxylipin_1 PL_Oxylipin_2 PL_Oxylipin_3 PL_Oxylipin_4 PL_Oxylipin_5 PL_Oxylipin_6 PL_Oxylipin_7 PL_Oxylipin_8 Factors Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 Genotype:Wild-type | Treatment:LPS+antiPla2g5 d5.EPA 1650.4 1178.857143 1178.857143 2750.666667 1031.5 1650.4 1650.4 1178.857143 0 0 0 0 0 0 0 0 634.7692308 687.6666667 634.7692308 750.1818182 687.6666667 687.6666667 750.1818182 687.6666667 0 0 0 0 0 0 0 0 266.1935484 266.1935484 266.1935484 266.1935484 266.1935484 266.1935484 266.1935484 266.1935484 0 0 0 0 0 0 0 0 589.4285714 458.4444444 458.4444444 458.4444444 375.0909091 330.08 458.4444444 284.5517241 0 0 0 0 0 0 0 0 LPC170 15544 11102.85714 11102.85714 25906.66667 9715 15544 15544 11102.85714 0 0 0 0 0 0 0 0 5978.461538 6476.666667 5978.461538 7065.454545 6476.666667 6476.666667 7065.454545 6476.666667 0 0 0 0 0 0 0 0 2507.096774 2507.096774 2507.096774 2507.096774 2507.096774 2507.096774 2507.096774 2507.096774 0 0 0 0 0 0 0 0 5551.428571 4317.777778 4317.777778 4317.777778 3532.727273 3108.8 4317.777778 2680 0 0 0 0 0 0 0 0 FA120 12730.64957 5335.539726 7266.85429 13486.37431 5352.275767 8245.123333 7038.873754 5331.82993 0 0 0 0 0 0 0 0 2533.373268 2214.334709 2124.615385 2995.27681 2496.687059 2810.503186 3048.310659 2561.707826 0 0 0 0 0 0 0 0 1435.817977 1792.477013 1298.590949 1252.90471 1268.430577 1557.773836 1020.510218 1199.178402 0 0 0 0 0 0 0 0 2722.799517 2579.596642 2999.625211 1781.410073 2325.563636 1553.259929 2416.579026 1235.734413 0 0 0 0 0 0 0 0 FA130 1049.485128 2078.664266 952.5037287 1516.722741 686.1787962 1142.902 965.7033223 589.2194801 0 0 0 0 0 0 0 0 324.8706621 229.7317667 260.9230769 303.7394019 374.2173968 269.037684 488.2253656 312.1408696 0 0 0 0 0 0 0 0 187.469929 395.2733173 212.4199178 169.4844443 313.9492016 214.9898572 154.2532472 167.61303 0 0 0 0 0 0 0 0 426.8275862 365.9427794 253.3936723 203.8708044 287.1260411 151.4992628 272.8793981 173.8565454 0 0 0 0 0 0 0 0 FA140 31562.13675 39338.30137 20639.3645 39806.55643 15760.60582 23621.35 26620.2392 15702.76187 0 0 0 0 0 0 0 0 7875.796446 7392.034508 6033.846154 8881.77615 7951.795065 8302.317073 8899.580142 8350.067246 0 0 0 0 0 0 0 0 4726.854873 4873.966379 4028.799236 4355.388429 4199.465377 4846.298079 3187.493978 3641.203498 0 0 0 0 0 0 0 0 12595.82396 10480.94179 11685.0851 7799.15557 10077.84575 6510.347206 10421.27656 5264.89422 0 0 0 0 0 0 0 0 FA141 1368.280342 950.5141292 848.6915245 1664.044572 730.8149095 831.389 1318.675083 666.1651041 0 0 0 0 0 0 0 0 462.7089825 393.2955436 391.8461538 345.6088627 408.2371601 393.6970995 400.4934979 314.2935652 0 0 0 0 0 0 0 0 113.2497132 122.3133467 131.0415517 129.7710942 131.012202 149.0158705 83.13823238 100.489372 0 0 0 0 0 0 0 0 1873.17102 1361.593546 1771.094629 1076.564983 1248.689736 783.2040904 1309.009705 694.7026837 0 0 0 0 0 0 0 0 FA150 9436.902564 21913.82387 5305.659815 11419.91373 4747.659323 7413.046667 6805.158472 4541.464552 0 0 0 0 0 0 0 0 2373.670939 2273.296285 1816.923077 2477.482887 2703.402568 2352.663151 2404.447968 2297.165449 0 0 0 0 0 0 0 0 1525.198506 1937.089202 1292.819433 1349.613814 1497.101826 1598.145977 1083.796728 1364.961024 0 0 0 0 0 0 0 0 2381.490845 1815.393556 1735.613601 1633.08536 1398.7261 980.6241141 1320.828011 766.9077742 0 0 0 0 0 0 0 0 FA151 960.6174359 1059.67953 433.2286622 1060.914929 470.7081039 544.2881667 784.0770764 435.7464146 0 0 0 0 0 0 0 0 205.2602713 163.5637769 160.9230769 180.2864297 333.7053122 243.652494 243.7161546 201.8750145 0 0 0 0 0 0 0 0 83.75413884 156.8417386 119.2732911 161.2746067 114.7146378 124.2674198 60.35996631 138.4572533 0 0 0 0 0 0 0 0 381.1919323 239.7689602 262.8552797 222.3357177 252.0368915 126.0858502 222.0783207 142.0226378 0 0 0 0 0 0 0 0 FA160 179075.453 106420.1174 130781.9726 221575.9885 92315.59795 146404.2333 174087.0432 100782.0402 0 0 0 0 0 0 0 0 57535.61616 45946.35334 34800 47295.14831 58145.2291 46282.64118 52911.73379 47167.95362 0 0 0 0 0 0 0 0 22035.73799 27869.08981 21607.99031 21971.75185 20896.25672 24797.68506 17120.28135 17754.95279 0 0 0 0 0 0 0 0 70160.02417 67460.4193 55749.56466 42514.70599 48519.82405 36815.10583 63942.32825 29468.06947 0 0 0 0 0 0 0 0 FA161 24036.59487 22708.34129 15042.06731 28139.45842 9617.053501 14619.79333 19026.20598 10893.66037 0 0 0 0 0 0 0 0 5594.334591 3544.245792 3241.538462 3884.693167 4027.836103 3513.128983 3400.22945 3520.853333 0 0 0 0 0 0 0 0 984.102537 1151.005906 1079.554904 1039.031482 805.4028813 887.5306472 595.5516676 730.2018506 0 0 0 0 0 0 0 0 28761.96673 18926.07289 19056.26859 13942.52302 18125.3607 11666.62069 18768.17579 11677.25611 0 0 0 0 0 0 0 0 FA170 10170.41368 10819.64775 5452.816289 9546.25689 4147.100708 5738.578333 5361.058472 3792.917448 0 0 0 0 0 0 0 0 2773.402068 2301.685191 1490.153846 2264.419359 2123.768127 2065.719842 2347.199207 2378.728696 0 0 0 0 0 0 0 0 1274.245483 1676.251661 1185.412941 1184.443013 1028.262596 1460.453999 948.8098946 1053.399518 0 0 0 0 0 0 0 0 2274.112836 2335.763801 2043.115841 1605.842045 1592.321408 1232.403329 1816.844085 1017.238048 0 0 0 0 0 0 0 0 FA180 114752.1709 46476.03914 56508.08638 117956.3384 48166.42408 66394.21667 78339.16944 49387.38154 0 0 0 0 0 0 0 0 35410.18921 27253.35027 20738.46154 31488.80749 31292.98842 25951.82377 34844.91696 28559.09565 0 0 0 0 0 0 0 0 9788.313777 12711.58997 10630.8497 9412.0918 8032.551403 10221.04451 7123.695418 8154.465429 0 0 0 0 0 0 0 0 28205.90204 23493.1007 23698.3697 19403.29408 15596.52199 12716.51843 18150.80159 9839.571442 0 0 0 0 0 0 0 0 FA181 155659.5214 86201.90998 109591.4402 194385.7177 83063.74902 129143.8 139475.2492 88487.46769 0 0 0 0 0 0 0 0 52212.20517 44068.31798 34092.30769 41943.78528 47030.37513 40865.62294 46517.71631 41236.08116 0 0 0 0 0 0 0 0 14587.36062 20031.46622 17399.00718 17184.99907 14945.75072 18741.86389 11503.756 12682.10913 0 0 0 0 0 0 0 0 89066.22363 76110.67961 67872.2491 53169.86904 59336.96188 47314.08323 72109.307 37433.78135 0 0 0 0 0 0 0 0 FA182 110026.6667 58393.80039 82514.64886 130908.7946 59366.03068 86439.7 108427.4419 64943.77946 0 0 0 0 0 0 0 0 34388.28442 31511.68625 27861.53846 33173.49586 28020.85851 30552.88947 28996.12578 28917.87826 0 0 0 0 0 0 0 0 3363.228861 4440.129811 3623.385476 4658.734971 3019.471194 3708.985323 2431.470158 2754.763293 0 0 0 0 0 0 0 0 80629.38005 84683.53267 62668.36504 52065.00128 57643.00293 43732.65636 81828.54089 32745.51496 0 0 0 0 0 0 0 0 FA183 13979.02906 6717.870841 10761.15168 18598.14522 7685.527144 10315 14550.66113 8861.292252 0 0 0 0 0 0 0 0 3899.873859 3437.241452 3007.692308 3562.620391 3046.19713 2824.102395 2929.352194 3016.165797 0 0 0 0 0 0 0 0 375.2836293 450.0831224 442.0136129 600.7096437 312.4331491 483.8092359 245.5858023 254.9496166 0 0 0 0 0 0 0 0 17782.56529 17385.66859 16498.67785 9388.348923 15778.0176 8571.875386 17064.22299 8276.815978 0 0 0 0 0 0 0 0 FA200 2341.593162 1563.196869 1229.693016 2803.069734 1270.100315 1808.563333 2046.550831 1337.766584 0 0 0 0 0 0 0 0 766.428592 460.3370382 372.4615385 639.1905848 683.5115811 519.7164359 824.5308586 567.594087 0 0 0 0 0 0 0 0 184.3759877 341.1776465 225.3706351 234.0499469 229.0502626 260.2854302 144.2542225 195.8536029 0 0 0 0 0 0 0 0 425.4853611 447.4139112 400.7877746 274.400719 300.6777126 179.1694649 320.6818007 119.7389025 0 0 0 0 0 0 0 0 FA201 3285.283419 2906.125088 3381.388237 4900.181165 2851.841857 3419.078667 5121.174751 2198.804845 0 0 0 0 0 0 0 0 1244.822625 1133.809252 1084 1074.23658 1316.383056 936.0788838 1287.477551 982.3467826 0 0 0 0 0 0 0 0 147.5924625 179.0691677 172.3008478 118.1381718 149.4575072 167.8890259 115.9033292 86.99665378 0 0 0 0 0 0 0 0 938.407101 1280.509451 992.4339102 400.3253732 1226.910264 672.0326754 1323.121115 422.8121729 0 0 0 0 0 0 0 0 FA202 5794.737778 4951.2 7309.663446 10648.69878 4040.785602 7805.016667 9136.142857 5210.556935 0 0 0 0 0 0 0 0 2333.032399 2343.17667 2056.923077 2129.148793 2283.47923 1711.233795 2298.12884 1898.916754 0 0 0 0 0 0 0 0 190.44928 246.9119232 203.9737978 163.7793029 155.6480549 192.8344139 149.4976135 152.5775398 0 0 0 0 0 0 0 0 1568.102426 2298.995357 1638.040775 820.4778255 1673.389443 1081.296552 2113.183703 809.5941503 0 0 0 0 0 0 0 0 AA 6160.788034 3113.151781 4149.812593 8988.609154 3309.159127 5906.369 5557.077741 3991.972432 0 0 0 0 0 0 0 0 4655.608098 4208.109453 3690.769231 4419.82947 5128.933787 3152.749945 4825.252725 4379.53971 0 0 0 0 0 0 0 0 54.63671282 60.7728262 39.24630423 36.59639479 48.80425617 38.68176286 51.69008024 38.73926738 0 0 0 0 0 0 0 0 1190.553676 1069.187655 1161.855817 594.8123693 989.0300293 503.6565517 1019.373007 449.7986445 0 0 0 0 0 0 0 0 EPA 1195.482051 637.2288063 1345.277738 2492.606278 774.6394571 1314.131 1271.383721 874.4201084 0 0 0 0 0 0 0 0 463.4219393 388.2728909 518.3076923 581.4652336 414.9891742 311.1952318 447.5812235 363.8055652 0 0 0 0 0 0 0 0 4.882697846 9.655095303 3.22923321 4.104918807 10.3521117 8.069504793 8.3930838 8.571536853 0 0 0 0 0 0 0 0 347.444558 256.7985554 400.7877746 226.7249184 318.4642815 137.9585256 264.5889445 113.4444707 0 0 0 0 0 0 0 0 DPA_n.3_n.6 1461.379829 767.3875538 1117.318981 2194.007668 891.0991345 1203.416667 1385.842525 861.0382608 0 0 0 0 0 0 0 0 636.4327967 713.2166825 500.7692308 807.1639246 620.6659114 508.8370688 622.3014686 517.1253333 0 0 0 0 0 0 0 0 18.13966367 21.65612168 17.35677658 15.01426235 21.40160754 14.12860825 16.79104517 14.78707776 0 0 0 0 0 0 0 0 744.5514453 678.0875193 734.6051095 382.9199222 677.2205865 363.4412366 606.2614681 286.2157693 0 0 0 0 0 0 0 0 DHA 9147.729915 4163.142074 6608.663511 11904.39492 3957.600118 7220.5 6661.228239 4462.009831 0 0 0 0 0 0 0 0 4272.987933 3893.647719 3421.538462 4209.243425 3708.413897 2966.894089 3457.230381 3104.665507 0 0 0 0 0 0 0 0 148.7383667 153.3246273 113.0513161 108.5646662 102.6999219 102.2104451 81.13842744 101.5614678 0 0 0 0 0 0 0 0 6854.935403 5933.265794 5823.323659 3676.333957 4403.083284 3049.609512 4602.083707 2182.793165 0 0 0 0 0 0 0 0 LPA151 8.693764505 3.15259585 7.717074205 9.243115143 6.006369295 2.006032756 18.06952418 10.74235112 0 0 0 0 0 0 0 0 44.08721374 33.18002894 23.31874909 48.06289198 31.68333333 35.82206985 44.69801879 41.99157509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPA160 667.1187713 294.2593787 1375.891166 690.249105 341.7290645 511.5444724 436.9056609 220.7826266 0 0 0 0 0 0 0 0 824.1661214 721.712494 771.8473606 975.6557648 414.6666667 853.3076653 630.2156685 643.8708181 0 0 0 0 0 0 0 0 19.49569588 29.36416614 17.77544429 16.0193019 26.29054796 19.05812827 24.3629983 21.17486852 0 0 0 0 0 0 0 0 54.68935205 34.50240082 26.46918915 36.53882561 19.29320356 25.69822222 15.66264891 15.72326622 0 0 0 0 0 0 0 0 LPA161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32.38245775 18.12716836 19.61556355 29.60736973 7.375 11.19752813 21.63190535 16.32926618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPA170 17.38752901 8.406494782 174.8994245 43.13704403 18.01910788 34.09888504 36.1340374 8.353543551 0 0 0 0 0 0 0 0 40.64093011 38.71003377 27.57175256 43.76969248 19.11666667 26.87224566 25.95652666 17.8855641 0 0 0 0 0 0 0 0 1.455074934 1.074282775 0.323171971 2.345204332 1.878480933 1.874366916 0.870271432 0.941286086 0 0 0 0 0 0 0 0 7.373782023 3.262510613 2.28211473 2.149053404 1.429005077 0.976016296 1.220371052 0.736925056 0 0 0 0 0 0 0 0 LPA180 1706.259044 932.0244214 2895.374054 2317.123851 1116.986797 2136.994016 1790.917344 1326.589327 0 0 0 0 0 0 0 0 1768.111613 1578.207139 1118.717796 1729.845263 1101.833333 1211.528364 1369.096796 1278.489255 0 0 0 0 0 0 0 0 40.44735447 80.20524844 34.57486586 47.49441267 38.36357356 36.85842008 46.84987759 42.04340982 0 0 0 0 0 0 0 0 74.35652048 58.73656858 67.08498334 78.97894204 32.15533926 53.67940741 34.98653508 31.44653244 0 0 0 0 0 0 0 0 LPA181 264.1286348 210.1944309 214.7598587 357.3916788 289.4710864 274.8350551 442.6682656 278.0994424 0 0 0 0 0 0 0 0 1174.888522 955.4723589 924.987828 1370.420695 479.1666667 1151.179677 631.5354919 839.3570208 0 0 0 0 0 0 0 0 7.56567943 8.773200084 8.079299278 6.449759129 6.439219825 5.309594537 7.252261936 8.471861952 0 0 0 0 0 0 0 0 17.20736624 13.28470429 11.86588269 18.26121657 4.644539003 3.579288889 2.644778512 4.052975391 0 0 0 0 0 0 0 0 LPA182 128.2512628 125.0714574 109.3023322 252.6746009 110.5259902 190.2610079 139.1543778 100.2498056 0 0 0 0 0 0 0 0 1270.29174 970.2815244 1061.148624 1459.16427 474.8333333 1282.808134 731.1821578 853.8286935 0 0 0 0 0 0 0 0 2.036572238 2.506004357 6.448651199 3.80134188 2.376953651 5.62214784 6.381459527 2.508054047 0 0 0 0 0 0 0 0 125.9898683 44.75641195 45.18280841 60.71772547 13.2218395 11.38503704 17.08991089 14.74149888 0 0 0 0 0 0 0 0 LPA183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.01970204 13.21015051 20.66668609 13.73038499 7.648333333 31.3585443 7.210635118 20.22001099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPA200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23.43052589 22.73863 13.25222946 36.88486645 18.58333333 16.42395218 20.18889845 25.66942613 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPA201 6.520654949 6.829074708 1.929072388 9.243115143 6.006369295 12.03742047 13.13873888 4.773973668 0 0 0 0 0 0 0 0 26.18335001 17.5123068 13.78102495 32.61784499 17.21666667 12.68916549 31.71975546 20.99578755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPA202 8.693764505 10.50972155 177.4495507 33.89674891 28.22883629 12.03742047 9.856559639 14.321921 0 0 0 0 0 0 0 0 66.80326619 72.50867342 82.68291546 105.1048536 31.68333333 105.9859587 41.09050153 65.71562882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPA204 160.8777474 59.89066458 88.74439172 246.470537 94.29156922 80.22907087 123.1694133 99.08453357 0 0 0 0 0 0 0 0 582.7161282 404.5339122 468.3155157 638.4825356 249.6666667 507.612166 374.8298426 365.5876679 0 0 0 0 0 0 0 0 2.910149867 5.729726615 0.969417325 1.759350466 2.41460512 1.561813612 1.160184917 2.196940472 0 0 0 0 0 0 0 0 55.3080523 15.38812765 18.71361926 25.26080317 9.289078006 3.253718519 1.627078662 6.632550336 0 0 0 0 0 0 0 0 LPA205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16.53165445 19.04571153 9.806164666 31.75396948 18.56666667 19.40950422 18.74589154 9.33067033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPA225 93.43641638 57.80667464 92.58919738 77.02439284 100.8879479 130.4104882 137.9517473 41.18508176 0 0 0 0 0 0 0 0 139.826654 88.48007718 118.7283327 143.2986224 144.2166667 97.40050398 112.4929469 108.4900977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6.145755777 5.128427756 7.758354653 4.835779971 6.07354408 7.645940741 6.509555747 3.439183445 0 0 0 0 0 0 0 0 LPA226 84.74928328 63.06474155 65.59709238 157.1696178 51.6349868 83.22771654 105.1299549 68.02275219 0 0 0 0 0 0 0 0 117.4468244 81.11298601 92.75752065 130.4190239 62.81666667 91.06958509 79.32138571 89.41595849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22.74192117 3.029270971 6.84634419 9.671559943 1.429005077 0.650644444 4.475397145 1.228333333 0 0 0 0 0 0 0 0 LPC140 519.5038225 295.7342024 385.7752448 901.1872762 388.0869483 499.4274961 494.3813798 360.469606 0 0 0 0 0 0 0 0 999.6323915 903.9214665 866.6100997 1129.320893 932.5 723.273324 1175.302728 911.2409035 0 0 0 0 0 0 0 0 2.327764781 7.442636306 1.289533064 2.923902731 2.146133771 2.494708991 4.641624631 4.063621919 0 0 0 0 0 0 0 0 468.8997925 408.3115942 505.8525207 469.6443938 343.3536226 321.1037037 235.9326115 321.8098434 0 0 0 0 0 0 0 0 LPC150 328.1879522 241.1657275 264.899263 593.1461055 230.6167295 280.8323465 385.9943005 242.3037436 0 0 0 0 0 0 0 0 1275.545221 1177.984756 1019.750567 1122.514601 1180.5 847.1589311 1229.415487 1104.591941 0 0 0 0 0 0 0 0 1.746267477 4.65478839 2.261612269 3.225326781 1.610009584 1.874366916 2.320369835 1.88295508 0 0 0 0 0 0 0 0 240.9181261 264.243449 232.5278584 247.1985151 198.7090965 212.8118519 222.1564306 185.4865772 0 0 0 0 0 0 0 0 LPC160 88197.61092 65148.73149 59280.62595 117595.2104 57718.31384 71722.70866 88944.5519 56115.12908 0 0 0 0 0 0 0 0 54804.31526 55768.69272 52701.66663 67199.04342 61883.33333 55566.33849 63747.46972 61184.33455 0 0 0 0 0 0 0 0 538.351092 845.4214351 531.5873302 545.604364 692.4596379 481.7894827 733.0138574 751.8418505 0 0 0 0 0 0 0 0 39990.53409 38043.66125 39641.12652 41423.78301 34073.7595 27296.2963 37989.99074 26162.97539 0 0 0 0 0 0 0 0 LPC161 1395.246416 745.106555 657.1479051 1676.037252 722.6699359 784.543622 934.5441651 570.9832732 0 0 0 0 0 0 0 0 1321.145437 978.7171249 1028.806392 1226.179663 1320.166667 939.1622128 1214.237518 1145.160073 0 0 0 0 0 0 0 0 7.275374669 5.371413873 3.555088859 7.622361295 5.366152939 8.120668457 6.671726996 7.84484844 0 0 0 0 0 0 0 0 1665.991026 1634.099693 1228.638217 1555.481903 954.0870663 898.2962963 843.6979975 1038.724832 0 0 0 0 0 0 0 0 LPC180 55014.08874 46969.92698 40056.59768 71196.33285 38442.22935 43272.29291 65042.2695 32522.01284 0 0 0 0 0 0 0 0 24859.47276 30330.67053 26019.32544 27722.55044 30383.33333 24868.21378 32137.69954 24483.22344 0 0 0 0 0 0 0 0 377.7513022 675.6598496 397.2116753 397.307309 509.1952018 393.2644769 508.4990492 423.5930976 0 0 0 0 0 0 0 0 14586.32701 17123.20304 14244.0718 13610.67156 14388.1518 11772.14815 17760.10348 10027.51678 0 0 0 0 0 0 0 0 LPC181 13594.3686 7412.59189 5402.344271 12887.53266 6449.792531 6915.244094 8874.411348 5338.402286 0 0 0 0 0 0 0 0 6455.477626 5636.855765 6382.739435 7445.036209 6613.333333 5966.549461 7406.408921 6566.818071 0 0 0 0 0 0 0 0 80.31765055 97.22510366 60.75002093 52.47640662 77.26736385 69.0285406 89.91211869 81.58833832 0 0 0 0 0 0 0 0 9848.583008 8598.578539 7195.832169 7512.671054 7853.53286 5261.733333 6771.427294 5645.536913 0 0 0 0 0 0 0 0 LPC182 14230.98294 10015.97624 7740.613831 15895.56362 8512.99321 8139.181102 12833.07028 6915.160943 0 0 0 0 0 0 0 0 3923.299716 4688.319344 4484.250432 4968.593082 3890 3844.097515 4183.840145 3824.31746 0 0 0 0 0 0 0 0 49.76018916 70.89785649 38.13389824 37.53042478 59.562988 39.98395311 56.56675814 65.5827415 0 0 0 0 0 0 0 0 26210.39224 26552.34226 21637.62227 20015.21134 21800.23001 14819.40741 20167.83239 16974.83221 0 0 0 0 0 0 0 0 LPC183 319.5008191 184.962122 149.1627663 338.9674891 108.107318 76.25127559 169.1700322 100.2498056 0 0 0 0 0 0 0 0 165.2955306 170.8115388 151.0705645 225.6809323 118.55 109.7207454 131.9383448 127.5405128 0 0 0 0 0 0 0 0 1.163882391 1.432158549 0.969515913 1.172602166 1.073066886 0.937088167 0.290090477 1.568969688 0 0 0 0 0 0 0 0 776.1875814 865.2621871 603.8762406 683.402261 367.9878825 289.042963 322.1888793 399.6767338 0 0 0 0 0 0 0 0 LPC200 190.1885324 113.497298 91.29451792 231.0543783 90.70020747 92.28485039 116.6050548 72.79308438 0 0 0 0 0 0 0 0 193.5382452 185.2645345 186.7763883 179.9217084 208.1666667 160.481962 256.0457376 160.9677045 0 0 0 0 0 0 0 0 3.200454629 3.22262984 3.555088859 1.172602166 1.073066886 2.498520616 1.740719857 0.313793938 0 0 0 0 0 0 0 0 50.39594732 44.28708827 44.27775986 46.75133721 27.87159406 43.76340741 33.36069752 35.37360179 0 0 0 0 0 0 0 0 LPC201 302.1265529 263.8010643 200.7930136 465.3047896 216.214636 302.9244094 294.0431721 222.0207281 0 0 0 0 0 0 0 0 426.3725294 340.9857212 332.3164312 335.6025464 336.5 276.4653071 405.1857806 376.2634921 0 0 0 0 0 0 0 0 4.074032258 3.580942582 4.200841272 2.638578482 3.219200657 3.747780925 3.770822222 4.07893828 0 0 0 0 0 0 0 0 86.95550731 110.4759479 68.92292809 73.07765123 75.74489916 61.49111111 54.11184568 53.06040268 0 0 0 0 0 0 0 0 LPC202 935.6904437 582.875954 484.9163049 1149.631834 483.3679743 678.0611024 684.9983237 532.3836387 0 0 0 0 0 0 0 0 494.8779235 424.0295224 355.6028381 456.5451177 439.1666667 391.2416784 519.5704744 447.9101343 0 0 0 0 0 0 0 0 9.605802796 6.803572423 6.462453541 6.156384979 6.975344012 4.060334228 7.251376974 4.706909064 0 0 0 0 0 0 0 0 132.4393496 143.6414873 111.139962 96.71559943 133.6354099 73.53125926 119.3935678 83.78747204 0 0 0 0 0 0 0 0 LPC203 799.7467577 471.302339 366.5119838 870.4489598 420.335911 416.1997795 567.2407479 301.4048822 0 0 0 0 0 0 0 0 490.2548601 482.3288953 492.4104784 672.7757755 371.8333333 294.9115096 433.781954 368.1973138 0 0 0 0 0 0 0 0 7.275374669 6.445259681 2.261612269 2.345204332 4.560738892 2.654797268 5.946058322 4.392923672 0 0 0 0 0 0 0 0 604.0764221 432.346655 334.0325343 343.9141146 455.2978037 162.9837037 324.0505254 183.5380313 0 0 0 0 0 0 0 0 LPC204 4285.210239 2135.288148 2042.062595 3962.140784 2209.053942 2376.885669 3469.088072 1988.609474 0 0 0 0 0 0 0 0 924.4025416 857.80685 1082.817919 1007.3312 929.8333333 729.1943272 840.0675875 758.220757 0 0 0 0 0 0 0 0 23.27764781 21.48784033 18.74160821 22.87066162 19.58694933 19.99197656 21.752361 24.47745877 0 0 0 0 0 0 0 0 5900.150528 5741.392915 3616.017055 3260.463174 5107.793891 2638.311111 4471.673853 2793.914989 0 0 0 0 0 0 0 0 LPC205 167.3765188 57.80667464 78.26925795 197.21403 74.4657865 74.23177953 73.91166989 33.42145715 0 0 0 0 0 0 0 0 39.9474706 47.31434636 71.55718774 55.78541547 42.61666667 27.32770745 38.20888713 28.77727717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367.4704492 278.3231591 310.7797485 310.8013161 345.097641 151.2711111 194.4799591 180.090604 0 0 0 0 0 0 0 0 LPC225 389.064198 156.5877975 155.5969308 363.5957426 255.8662014 204.5810709 233.2602192 117.5832264 0 0 0 0 0 0 0 0 57.85133432 61.12998553 77.39496057 95.23573041 56 64.94885138 56.95037926 36.15545788 0 0 0 0 0 0 0 0 1.746267477 0.716079275 0.969417325 2.345204332 1.341538235 1.874366916 3.770822222 3.137939376 0 0 0 0 0 0 0 0 315.9120953 226.9819939 185.3260955 176.7108749 327.9844605 131.4192593 221.2876625 108.0693512 0 0 0 0 0 0 0 0 LPE140 8.693764505 4.203247391 1.286048258 24.6470537 6.006369295 0 14.78233398 2.387350982 0 0 0 0 0 0 0 0 16.52955306 15.36216594 10.07137097 7.722523494 10.925 5.224146742 10.81595268 4.666521368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPE150 10.86886348 5.254860773 6.430241292 33.88734881 10.8107318 18.05307087 21.35170342 16.71072858 0 0 0 0 0 0 0 0 14.1507768 11.17810806 9.599174383 15.8534245 9.668333333 8.758530239 8.864813767 6.917934066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPE160 1632.650512 1076.621261 1351.566885 3025.891147 1467.694266 1839.577323 2181.27118 1599.335801 0 0 0 0 0 0 0 0 1930.128971 1583.455958 1445.374337 1992.934622 1738.333333 1533.084388 2076.962074 1747.988278 0 0 0 0 0 0 0 0 27.64553596 38.31106051 24.23296843 32.25326781 33.80447169 23.11750959 36.54892226 36.71140179 0 0 0 0 0 0 0 0 315.9120953 260.5457473 420.7779569 441.6132625 513.3954167 343.1392593 527.2181661 419.761745 0 0 0 0 0 0 0 0 LPE161 39.12525597 18.39040964 15.43022514 40.05381229 27.62783289 20.06032756 14.78233398 23.87350982 0 0 0 0 0 0 0 0 108.8311153 87.86146647 68.37147791 116.7017279 59 40.3083685 80.04728858 83.20025641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.06161046 4.195469185 7.303045613 10.20923311 5.002062775 3.903866667 1.627078662 7.369250559 0 0 0 0 0 0 0 0 LPE170 43.47545392 27.32271111 56.5735689 67.78409773 38.44222935 68.17329134 75.56528691 44.17109122 0 0 0 0 0 0 0 0 90.23379208 61.44866377 41.34954329 92.25143319 56.26666667 61.2140647 69.95063965 67.66100122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6.758831476 5.593484848 4.56422946 11.82061335 8.575120473 4.555007407 9.356633132 7.123434004 0 0 0 0 0 0 0 0 LPE180 3285.195222 1508.167485 2299.429177 5454.876149 2533.742361 4337.020787 2907.359381 2977.99822 0 0 0 0 0 0 0 0 2765.432473 2071.408587 1725.458064 2905.763077 2115 2237.228317 2564.856787 2621.507937 0 0 0 0 0 0 0 0 71.87484236 71.07264319 56.55016554 56.29563716 52.85120428 36.22950185 60.3366954 72.95374004 0 0 0 0 0 0 0 0 363.1582959 288.8473869 402.9554624 422.2701426 429.1375277 349.7896296 436.4939478 330.8780761 0 0 0 0 0 0 0 0 LPE181 730.1170648 404.6146611 526.1106512 1161.851959 524.7785741 684.1807874 716.0662798 470.4785644 0 0 0 0 0 0 0 0 1793.748601 1483.16604 1180.491459 1574.609451 1381.333333 1198.775434 1651.09906 1358.676557 0 0 0 0 0 0 0 0 19.20272777 23.62897744 13.5755889 20.81346484 16.90223584 16.86644352 22.33643579 18.51365086 0 0 0 0 0 0 0 0 125.9898683 118.4117845 139.3774768 153.6630558 114.0152029 105.7111111 136.2724921 115.7136465 0 0 0 0 0 0 0 0 LPE182 419.5023208 179.7040551 240.4572842 533.0794872 284.6703885 270.796063 410.5981173 183.8216558 0 0 0 0 0 0 0 0 345.4689198 332.3626628 275.5558145 453.9273131 247.5 245.4939053 245.9270916 275.1990232 0 0 0 0 0 0 0 0 16.29968016 14.32158549 11.30806134 9.67776921 6.975344012 13.42645137 5.221274609 8.471861952 0 0 0 0 0 0 0 0 243.9178849 207.4979505 308.1342219 313.7519615 243.2905669 164.9688889 230.2235636 208.5693512 0 0 0 0 0 0 0 0 LPE183 23.91282594 3.15259585 5.14340838 52.37733914 1.201273859 18.05307087 4.927277627 13.12751722 0 0 0 0 0 0 0 0 13.77672894 23.95710564 11.13219617 13.73038499 8.741666667 2.985552039 7.932138571 6.220446886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.9064621 11.65344898 18.71361926 20.4250232 10.00412555 8.458874074 8.13663441 8.843400447 0 0 0 0 0 0 0 0 LPE200 13.04396246 1.050972155 1.286048258 12.32352685 3.603455111 4.011453543 6.569369439 4.773973668 0 0 0 0 0 0 0 0 15.153141 16.59001447 9.540958365 18.02096669 8.74 14.9277602 21.62970565 17.8831917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPE201 34.77505802 7.358087538 30.86437355 21.57322206 15.6150943 50.1508189 29.56466796 23.87350982 0 0 0 0 0 0 0 0 65.43736109 47.08939701 31.2749381 48.90058944 52.45 47.77794187 52.63895619 66.09521368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3.072877889 2.797453521 3.195517575 1.611872016 2.500486382 3.579288889 2.034158602 3.685 0 0 0 0 0 0 0 0 LPE202 63.03808191 35.71638134 25.72096517 83.19085631 37.23289325 44.12904882 69.00092843 35.80662325 0 0 0 0 0 0 0 0 79.20148168 56.53726966 39.74860282 58.35086396 47.8 44.04315518 67.77293105 40.42578755 0 0 0 0 0 0 0 0 0.581941195 1.790471291 0.969417325 1.172602166 1.073066886 0.312362722 0.870182936 1.88295508 0 0 0 0 0 0 0 0 3.687828436 1.864494949 2.738816152 2.149053404 2.858010154 2.277007407 2.847077385 1.474149888 0 0 0 0 0 0 0 0 LPE203 69.56337884 30.47434512 42.44979303 92.34655056 48.04362505 46.13630551 62.43656995 32.22705337 0 0 0 0 0 0 0 0 55.79196972 65.14158225 49.28956118 87.51320691 33.05 25.36922175 41.81640439 44.31653236 0 0 0 0 0 0 0 0 1.746267477 2.506004357 0.323171971 1.759350466 0.536615294 1.561813612 1.446027578 3.451924768 0 0 0 0 0 0 0 0 17.20549139 5.593484848 7.30165323 16.11872016 11.07451684 7.483155556 11.79787167 1.965033557 0 0 0 0 0 0 0 0 LPE204 1195.641297 472.2641805 487.2702675 1444.794872 683.458129 631.5514961 768.6813669 463.1956145 0 0 0 0 0 0 0 0 240.399297 336.674192 287.3607291 468.5870188 179.1666667 117.9418308 154.3093513 210.7407692 0 0 0 0 0 0 0 0 37.25133876 42.61518308 32.64253802 30.78639706 13.68549072 47.47379753 38.57548478 35.7732747 0 0 0 0 0 0 0 0 238.4808221 164.9743815 218.6040345 241.7889986 167.4257665 89.15466667 152.5308677 87.23489933 0 0 0 0 0 0 0 0 LPE205 10.86886348 4.203247391 7.717074205 70.86732946 18.01910788 26.07597795 34.4904423 5.968377454 0 0 0 0 0 0 0 0 16.52955306 22.73863 21.20033291 27.46076998 13.65666667 8.21197609 12.25675988 18.66371306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17.20736624 7.924459084 16.43011215 9.13388678 13.2218395 2.928148148 9.763713072 5.650033557 0 0 0 0 0 0 0 0 LPE225 273.8767918 75.66486531 100.3180414 369.7058055 130.9381177 132.3687874 223.3886267 116.9641756 0 0 0 0 0 0 0 0 23.40951196 22.1200193 12.19140426 40.34036849 21.3 9.703613455 20.18889845 20.99578755 0 0 0 0 0 0 0 0 4.656417344 8.951264038 3.231719711 4.397928947 1.610009584 5.62214784 7.251376974 5.333922576 0 0 0 0 0 0 0 0 11.06161046 11.65487118 15.97062596 20.4250232 28.58010154 11.05748148 17.89662419 12.0360179 0 0 0 0 0 0 0 0 LPE226 1206.251536 462.3251516 474.7158001 1355.493953 710.9430404 712.3313386 997.1811734 524.0082463 0 0 0 0 0 0 0 0 133.6275463 188.020164 169.6350055 248.8485028 117.45 77.63346226 87.96622891 122.8668742 0 0 0 0 0 0 0 0 25.60363703 25.78103872 18.4162673 20.51830182 10.46056049 28.73965743 24.94707309 14.11976992 0 0 0 0 0 0 0 0 279.5400203 149.6146977 264.6918915 281.6227115 354.7987434 133.4044444 285.9488359 139.0212528 0 0 0 0 0 0 0 0 LPG140 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24.79643099 17.81973758 14.84185015 26.59689447 6.555 16.42167487 18.74589154 16.32926618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPG160 154.3126621 65.14873149 174.8994245 274.2008224 208.4089212 230.6509291 279.2107286 229.1944338 0 0 0 0 0 0 0 0 369.2146546 316.8036662 249.6820291 421.204756 333.5 300.1493202 357.0122269 311.4968254 0 0 0 0 0 0 0 0 1.746267477 2.148784033 3.070035138 4.983782813 4.024614704 3.123627224 2.46550357 6.902892264 0 0 0 0 0 0 0 0 23.96057317 9.090657298 14.14660504 9.13388678 12.14272811 9.435585185 14.23538692 12.0360179 0 0 0 0 0 0 0 0 LPG161 97.81313993 52.54860773 63.00773347 101.7090469 61.27302905 94.30434646 113.3479304 68.02275219 0 0 0 0 0 0 0 0 108.8311153 78.33861071 96.99435301 139.4504497 71.56666667 117.9418308 81.47709725 81.65819292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21.50452067 3.728989899 3.650826615 6.984833376 1.786528849 2.928148148 2.034158602 1.228333333 0 0 0 0 0 0 0 0 LPG170 54.33768601 47.29054082 115.1087733 206.4261248 85.27651829 154.4608504 119.9122888 132.4768589 0 0 0 0 0 0 0 0 19.97583669 14.13244284 14.31143755 19.73562868 15.29666667 20.90114158 23.80081513 16.32926618 0 0 0 0 0 0 0 0 1.455074934 1.790471291 1.939229003 1.759350466 1.877662422 1.561813612 1.450452387 2.509968592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPG180 56.51278498 24.1710771 33.4341161 67.78409773 52.8443229 74.23177953 87.04038685 59.68377454 0 0 0 0 0 0 0 0 65.43736109 62.06727448 64.13464555 90.96870895 69.93333333 81.36824895 105.2779124 116.6511722 0 0 0 0 0 0 0 0 1.163882391 1.074173533 2.262598151 1.465976316 1.877662422 1.561813612 2.320369835 1.88295508 0 0 0 0 0 0 0 0 9.218633666 5.593484848 9.12845892 14.50733991 11.07451684 9.761155556 6.916635687 13.01778523 0 0 0 0 0 0 0 0 LPG181 852.1348123 298.45942 368.4343867 1174.072085 598.804602 728.8544882 1044.7853 506.165019 0 0 0 0 0 0 0 0 158.4239773 181.8715485 255.9887643 241.5448281 158.4333333 151.5321378 205.1445489 204.5013431 0 0 0 0 0 0 0 0 10.7687974 13.61151451 11.95874317 9.67776921 10.19863722 10.3104474 8.991211869 9.725888975 0 0 0 0 0 0 0 0 33.80353163 28.89896062 40.39301301 30.09658314 27.15218647 22.12488889 25.62866085 20.63210291 0 0 0 0 0 0 0 0 LPG182 259.7519113 269.0270698 249.4808077 451.3926463 321.316937 431.2542047 556.7177305 303.1892049 0 0 0 0 0 0 0 0 63.37799649 63.90436083 65.99432388 101.2566809 52.45 73.14716362 63.43951092 78.92992674 0 0 0 0 0 0 0 0 2.910149867 5.013101131 7.432560983 5.277156963 2.950729308 7.183961452 9.858474432 7.216877656 0 0 0 0 0 0 0 0 16.59241569 20.05292051 7.303045613 10.74690627 6.788591624 11.05748148 14.23538692 7.86163311 0 0 0 0 0 0 0 0 LPG200 71.75174061 21.01623695 68.14721858 70.86732946 56.4723312 57.17009764 50.91136041 58.4820878 0 0 0 0 0 0 0 0 77.83557659 70.05297636 45.31146668 96.09960591 59 46.27491796 74.26206272 59.49992674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.44665991 9.32389694 14.60609123 11.82061335 16.43737343 6.833007407 13.01911149 8.596085011 0 0 0 0 0 0 0 0 LPG201 69.56337884 13.13554886 163.3257749 46.22027576 10.8107318 42.12791181 37.7776325 15.51632479 0 0 0 0 0 0 0 0 15.84239773 16.51315678 11.13057906 17.16232679 10.38 11.19752813 15.86207744 5.442297924 0 0 0 0 0 0 0 0 1.163882391 1.790471291 0.323171971 1.759350466 0.80484109 1.249260308 1.450452387 1.254984296 0 0 0 0 0 0 0 0 6.145755777 2.330974235 1.3691296 1.611872016 2.144052621 1.95242963 0.40683172 1.228333333 0 0 0 0 0 0 0 0 LPG202 58.68788396 26.27430387 146.6126401 80.11702467 9.608725009 30.09049134 21.35170342 46.53804995 0 0 0 0 0 0 0 0 29.62963364 23.03856247 12.72181686 43.76969248 18.03333333 34.34181903 31.36780256 38.10083028 0 0 0 0 0 0 0 0 4.946722105 5.013101131 1.939229003 3.517806498 4.560738892 1.561813612 3.770822222 1.88295508 0 0 0 0 0 0 0 0 8.603683119 2.330974235 4.56422946 4.298106808 1.786528849 0.325371852 1.220371052 2.087941834 0 0 0 0 0 0 0 0 LPG203 19.56262799 39.94848397 6.430241292 46.22027576 19.21745002 18.05307087 9.856559639 13.12751722 0 0 0 0 0 0 0 0 109.5245748 82.95007236 87.46956576 117.1205766 15.29666667 8.21197609 45.07196875 82.41736264 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPG204 97.81313993 1.050972155 48.21700151 168.8257378 81.68515654 96.26264567 116.6050548 60.26641053 0 0 0 0 0 0 0 0 82.64776531 67.89721177 71.55718774 91.80640641 39.33333333 71.6669128 43.26821012 48.53941392 0 0 0 0 0 0 0 0 1.455074934 6.803572423 0.969417325 1.465976316 0.536615294 2.81107392 3.770822222 0.941381813 0 0 0 0 0 0 0 0 9.218633666 6.059964134 6.84634419 8.329016283 2.500486382 0.976115556 4.068317205 0.245666667 0 0 0 0 0 0 0 0 LPG225 115.1874061 59.89066458 66.85253912 103.2130624 74.4657865 110.3379213 152.7340812 101.4514923 0 0 0 0 0 0 0 0 44.08721374 27.94995658 35.77050831 41.17806595 21.85 20.94668776 24.50472093 26.42859585 0 0 0 0 0 0 0 0 1.163882391 2.864317099 1.939229003 0.586390526 1.073066886 1.249260308 0.870182936 1.568969688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPG226 327.1269283 91.43906605 187.7677537 425.1663764 213.7959638 234.6899213 266.0820116 160.5162161 0 0 0 0 0 0 0 0 100.9088658 96.46577906 104.5786064 90.10483344 72.93333333 67.56775668 71.73240122 59.09661783 0 0 0 0 0 0 0 0 3.200454629 4.65478839 3.555088859 3.664493573 1.073066886 1.874366916 2.755771039 5.647907968 0 0 0 0 0 0 0 0 10.44665991 5.593484848 5.932941345 3.22439973 2.144052621 0.976016296 4.881235987 0.982516779 0 0 0 0 0 0 0 0 LPI160 200.0030034 85.12297347 145.3179606 335.8654572 139.3301773 206.6005669 203.6454417 164.7039123 0 0 0 0 0 0 0 0 243.7615249 121.0602412 155.8410437 243.6914278 186.8333333 138.096015 239.9878863 195.9606838 0 0 0 0 0 0 0 0 2.618957324 1.790471291 0.969515913 3.225326781 2.41460512 1.561813612 2.900904774 1.254984296 0 0 0 0 0 0 0 0 5.53080523 4.66194847 6.389642768 6.447160213 4.287015231 3.904859259 4.475397145 4.913333333 0 0 0 0 0 0 0 0 LPI161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6.199107746 1.536216594 2.120033291 4.290581697 1.638833333 0.746501875 2.883814106 1.555348962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPI170 49.99411945 25.22269048 24.43413226 46.22027576 25.22381931 54.1592126 47.63419213 36.99738556 0 0 0 0 0 0 0 0 57.87234825 23.35724071 29.69016874 25.74349018 0 26.12073371 33.89746406 21.7715641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPI180 2234.78157 1376.715812 2062.855931 4082.462022 2375.795737 3479.040945 3025.618053 2385.530244 0 0 0 0 0 0 0 0 1876.963742 1414.36903 1332.499948 1707.332143 1575.5 902.0420769 1809.037926 1571.481319 0 0 0 0 0 0 0 0 59.36599196 62.31145969 45.56744511 61.27763111 44.00310891 41.53719057 35.9736971 55.22505265 0 0 0 0 0 0 0 0 89.11158392 120.2748573 155.6683507 102.0923311 96.4769179 134.397037 109.0179937 75.1689038 0 0 0 0 0 0 0 0 LPI181 263.0012969 174.4459882 276.4729127 656.3147557 312.3385326 437.2514961 538.6782721 331.8476128 0 0 0 0 0 0 0 0 345.6790591 191.7693198 181.2782089 315.7072316 162.25 126.8916549 210.5338277 210.7407692 0 0 0 0 0 0 0 0 3.492534954 6.445259681 6.785822688 3.225326781 3.756143355 2.81107392 3.480554752 8.472819224 0 0 0 0 0 0 0 0 9.831709365 7.459401991 3.422475904 3.760433645 1.786528849 4.229437037 2.441238542 4.912583893 0 0 0 0 0 0 0 0 LPI182 19.56262799 10.50972155 21.86046643 58.54380261 55.2629951 90.26535433 82.12964539 32.22705337 0 0 0 0 0 0 0 0 45.45311883 36.87294742 39.74860282 49.76446495 29.5 20.15418425 30.28994679 22.93878755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6.760706325 1.864494949 9.58376796 6.447160213 1.071808308 3.579288889 0.813663441 1.965033557 0 0 0 0 0 0 0 0 LPI200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11.70895877 2.457571635 0 5.149221597 0.546333333 0 2.883814106 6.998595849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPI201 17.38752901 6.306474155 2.572096517 6.161763425 3.603455111 36.10614173 16.42592908 4.773973668 0 0 0 0 0 0 0 0 4.820594295 5.530004824 4.770479183 6.863883593 4.37 3.732509376 10.09444922 3.110223443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPI202 17.38752901 19.96782971 15.43022514 58.54380261 13.21108072 52.15195591 52.56497743 29.83824579 0 0 0 0 0 0 0 0 25.4898905 8.602438013 9.540958365 16.30368689 4.37 5.224146742 8.651442319 11.66511722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPI203 21.73772696 11.56133493 59.16292781 63.16865022 30.92968691 52.15195591 39.4212276 88.3057677 0 0 0 0 0 0 0 0 101.9385481 60.83005306 1.060178357 151.0211459 91.23333333 51.51272855 113.5488056 44.31653236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.457927341 4.66194847 1.369268838 4.298106808 1.071808308 0.650644444 0.813539331 0.982516779 0 0 0 0 0 0 0 0 LPI204 232.5631741 142.9296481 137.5891166 391.3260281 189.7924745 247.7248504 353.1223985 230.3597058 0 0 0 0 0 0 0 0 95.73944031 44.24003859 75.7940201 107.2514534 42.61666667 20.90114158 46.14982452 30.31934066 0 0 0 0 0 0 0 0 6.401797039 10.74282775 8.725051692 9.087443177 1.610009584 6.558854845 4.641624631 5.647907968 0 0 0 0 0 0 0 0 45.48384233 52.20870297 32.8602243 25.78536236 20.01261115 15.29585185 16.27078662 25.79574944 0 0 0 0 0 0 0 0 LPI205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.08747222 6.144866377 5.831304384 2.574349018 2.731666667 5.224146742 2.883814106 2.333023443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPI225 19.56262799 4.203247391 14.14339223 15.40675859 13.21474538 22.06758425 16.42592908 19.09953615 0 0 0 0 0 0 0 0 5.509851021 1.228973275 4.240066582 3.431941797 2.731666667 0.746501875 2.162970565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPI226 26.08129352 4.203247391 6.430241292 30.81351717 22.82347039 54.1592126 52.56497743 27.4530797 0 0 0 0 0 0 0 0 16.53165445 3.687294742 6.890512474 6.005243693 9.833333333 1.493003751 5.046124759 3.888372405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5.53080523 0.932247475 2.738816152 1.611872016 2.144052621 0.650743704 1.627078662 0.491333333 0 0 0 0 0 0 0 0 LPS130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3.444182236 7.987576459 3.709653981 2.574087238 6.008333333 2.985552039 3.605317559 3.888372405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPS150 17.38752901 23.11946372 7.717074205 36.97058055 14.41308751 20.06032756 21.35170342 17.90149089 0 0 0 0 0 0 0 0 26.18335001 22.1200193 25.43716527 13.73038499 7.101666667 30.60703235 18.74589154 28.77727717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPS160 439.0649488 346.9041706 376.7909541 739.505612 421.4353074 701.927874 598.8098001 415.4922926 0 0 0 0 0 0 0 0 101.2450885 63.90436083 67.04544641 125.2881269 56 58.5951594 98.78878071 61.42157509 0 0 0 0 0 0 0 0 5.819411953 14.32158549 6.140070275 9.087443177 4.560738892 4.372887532 4.64073967 8.471861952 0 0 0 0 0 0 0 0 6.145755777 0 4.107528038 3.22439973 0.71461154 4.229437037 4.882477085 2.210850112 0 0 0 0 0 0 0 0 LPS170 160.8777474 77.78091663 124.0930641 428.2684083 169.3437005 236.7094173 328.5185816 179.0513236 0 0 0 0 0 0 0 0 168.7628282 125.6529571 72.62448139 137.3038499 78.11666667 120.9251055 131.5863919 104.5756288 0 0 0 0 0 0 0 0 3.200454629 1.790471291 2.261612269 5.863905263 3.219200657 1.874366916 4.641624631 1.254984296 0 0 0 0 0 0 0 0 7.988732571 3.262510613 10.95387223 7.522506538 7.146115396 5.856296296 5.695395867 2.824642058 0 0 0 0 0 0 0 0 LPS180 1782.520137 1145.553236 1433.955578 3962.140784 1667.417955 2752.022362 2970.497485 1987.152884 0 0 0 0 0 0 0 0 2687.680952 2107.025567 1642.985373 2249.479471 1592.5 1604.591889 2228.301823 1672.545788 0 0 0 0 0 0 0 0 37.53542904 34.37835969 18.4162673 20.23208314 23.61401957 31.55073135 20.01783587 37.34320167 0 0 0 0 0 0 0 0 35.02218363 20.50802225 28.29321008 24.17889986 32.87474685 39.36622222 34.57697295 27.75928412 0 0 0 0 0 0 0 0 LPS181 386.8758362 267.9690442 490.4088844 794.9661829 362.7641833 587.7345512 583.2758221 479.9463993 0 0 0 0 0 0 0 0 821.6444505 594.8035697 588.9520401 978.2735693 628.1666667 553.3860759 648.2532548 629.1619048 0 0 0 0 0 0 0 0 2.910149867 13.96108792 7.755930131 8.209109595 8.839910271 9.058328368 7.541644444 9.725888975 0 0 0 0 0 0 0 0 14.7494389 9.32389694 14.14660504 9.13388678 7.146115396 8.134296296 17.08991089 7.86163311 0 0 0 0 0 0 0 0 LPS182 295.6277816 178.6460295 241.7519637 489.9330431 237.8360996 347.0473386 331.775706 277.5168064 0 0 0 0 0 0 0 0 61.99107746 56.21859141 69.69750942 96.09960591 55.71666667 51.51272855 102.396298 69.98595849 0 0 0 0 0 0 0 0 2.910149867 3.580942582 1.615859856 3.225326781 4.024614704 4.685440836 1.450452387 4.392923672 0 0 0 0 0 0 0 0 13.5195378 13.05288684 19.17310545 12.89432043 11.79392443 6.832014815 25.62866085 6.140917226 0 0 0 0 0 0 0 0 LPS200 6.521318089 5.254860773 23.14729934 15.40675859 10.8107318 6.017486299 8.212964539 16.71072858 0 0 0 0 0 0 0 0 136.3803704 64.52297154 53.54256466 78.50795918 59.55 55.24751524 119.6859844 81.65819292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPS201 17.38752901 14.71296894 11.57364967 21.56382196 16.81710109 18.05307087 24.63889362 14.321921 0 0 0 0 0 0 0 0 56.48542923 45.47726001 34.46064793 36.91104449 38.23333333 20.15418425 61.28379939 35.77587302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPS202 49.99411945 18.91621633 32.15120646 61.61763425 22.82347039 28.08323465 67.34731141 31.03264958 0 0 0 0 0 0 0 0 26.18335001 5.530004824 11.13057906 18.02096669 15.29666667 20.90114158 18.74589154 9.33067033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LPS203 186.9391468 73.58087538 104.162847 218.7402516 102.097284 122.3937008 136.3482398 95.47947336 0 0 0 0 0 0 0 0 103.6616899 77.42006753 68.37147791 96.54463269 54.08333333 52.26424051 77.86957998 82.41736264 0 0 0 0 0 0 0 0 2.036572238 1.432158549 0.969417325 2.931952631 0.268307647 2.498520616 0.580092459 0.941381813 0 0 0 0 0 0 0 0 4.915854682 4.195469185 10.95387223 8.596213617 6.07354408 2.277007407 6.102475807 3.685 0 0 0 0 0 0 0 0 LPS204 534.756041 386.3396725 342.070005 674.8329463 275.0689928 502.4873386 530.660735 286.4748348 0 0 0 0 0 0 0 0 84.37090712 62.98581766 50.35685483 106.3875779 52.45 60.46255274 58.40218499 52.88091575 0 0 0 0 0 0 0 0 8.148064516 17.54421533 9.694173252 7.036507429 8.048410898 6.559807751 9.858474432 12.23394302 0 0 0 0 0 0 0 0 132.7393255 42.42401552 68.90900426 82.4705391 20.72111862 25.05303704 55.73768324 15.47595078 0 0 0 0 0 0 0 0 LPS225 160.8777474 56.74864898 77.17074205 154.0675859 53.46731422 80.22907087 106.7835719 71.6278124 0 0 0 0 0 0 0 0 14.80851264 8.602438013 6.890512474 18.01834888 10.925 6.718061416 7.932138571 8.554893773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9.218633666 4.195469185 3.194125193 3.22439973 2.500486382 0.976016296 4.068317205 1.965033557 0 0 0 0 0 0 0 0 LPS226 628.1924573 370.9502083 439.7986875 751.8197388 297.8997925 473.4188346 586.2823985 430.7864874 0 0 0 0 0 0 0 0 113.643304 63.90436083 68.11274006 98.6650544 68.28333333 88.08631036 73.53615986 65.3123199 0 0 0 0 0 0 0 0 10.7687974 15.04258065 11.95874317 7.329881578 7.243815361 5.309594537 6.961994466 17.88185099 0 0 0 0 0 0 0 0 63.91361027 33.56375348 41.53476656 32.2439973 15.71796584 9.760162963 28.88033598 14.74149888 0 0 0 0 0 0 0 0 d5-EPA 0 0 0 0 0 0 0 0 1099.831555 1283.846547 1036.83729 2940.462772 1210.005938 1448.888889 1225.119368 667.1831256 0 0 0 0 0 0 0 0 1281.231713 936.995685 283.1789744 514.8244045 680.2374169 654.4500846 595.8863961 451.1508003 0 0 0 0 0 0 0 0 210.9503281 293.4477513 299.8709677 258.8750547 507.7647059 460.7526882 406.1919907 457.9428395 0 0 0 0 0 0 0 0 1281.774008 1117.830409 1270.676259 1250.018896 774.16547 908.2253353 1231.258278 524.6896552 d4-PGE2_d4-PGD2 0 0 0 0 0 0 0 0 13280 9485.714286 9485.714286 22133.33333 8300 13280 13280 9485.714286 0 0 0 0 0 0 0 0 5107.692308 5533.333333 5107.692308 6036.363636 5533.333333 5533.333333 6036.363636 5533.333333 0 0 0 0 0 0 0 0 2141.935484 2141.935484 2141.935484 2141.935484 2141.935484 2141.935484 2141.935484 2141.935484 0 0 0 0 0 0 0 0 4742.857143 3688.888889 3688.888889 3688.888889 3018.181818 2656 3688.888889 2289.655172 LTB4 0 0 0 0 0 0 0 0 1.818636721 0.399613007 0.179798705 3.67824055 0.618557007 1.727111111 0.111803953 0.171252157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.143037371 0.101153216 0.37791207 0.171426682 0.073125815 0.415024739 0.368400294 0.115567816 20-hydroxy-LTB4 0 0 0 0 0 0 0 0 2.433051095 0.912666423 1.404229607 4.273026346 2.453527316 0.778577778 3.080120158 0.886182167 0 0 0 0 0 0 0 0 0.432038697 1.206947141 3.505579487 1.858402117 1.038879392 2.135088228 3.173611724 0.730940747 0 0 0 0 0 0 0 0 0.086410669 0.561254437 0.165583156 0.02818469 0.213563567 0.433763441 0.010756007 0.020369498 0 0 0 0 0 0 0 0 7.153882852 5.31005848 3.468617106 1.218023432 0.670931183 0.995901043 1.374172185 0.342252874 LTC4 0 0 0 0 0 0 0 0 0.537314318 0.08743354 0.103225205 0.274118671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LTD4 0 0 0 0 0 0 0 0 0 0.74963829 0.376505481 3.46679496 1.419477435 1.600888889 0.992798103 1.182212848 0 0 0 0 0 0 0 0 0.115001416 1.294244876 0.295096923 0.19130191 0.414605888 0.740319072 0.813316042 0.333305251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LXA4_2 0 0 0 0 0 0 0 0 5.054751263 2.751584947 3.084146741 5.830726231 1.566353919 6.419555556 2.51007747 2.154339406 0 0 0 0 0 0 0 0 73.48183105 39.24816613 46.60769231 52.76475216 50.09164292 31.53077109 48.04979899 53.7950014 0 0 0 0 0 0 0 0 0.545425046 0.337218863 0.211115318 0.243855 0.339937761 0.293870968 0.148470176 0.368020348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LXB4 0 0 0 0 0 0 0 0 1.369756317 1.756434052 2.102905481 1.749369989 0.695938242 0.831555556 2.821868775 0.855624161 0 0 0 0 0 0 0 0 5.522888155 3.061688242 2.354646154 4.536058937 3.883186135 1.029625332 3.842692258 3.292030329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PGA2_PGJ2_12-HpEPE 0 0 0 0 0 0 0 0 40.40669287 12.92580197 26.51987915 28.18767468 14.87494062 17.53777778 21.49995257 18.0546884 0 0 0 0 0 0 0 0 333.6059462 218.9606257 219.2902564 286.8103855 258.0251662 127.3990815 239.3017767 229.6776186 0 0 0 0 0 0 0 0 2.333708509 1.582494052 1.274130964 1.49317011 1.280121442 1.922580645 1.030348543 1.485775173 0 0 0 0 0 0 0 0 1.347182613 0.149764035 1.061285372 0.048557823 0.366912626 0.439763934 0.867011038 0.135558621 PGB2_13.14-dihydro-15-keto-PGJ2 0 0 0 0 0 0 0 0 0.074490286 0.035948674 1.100457488 3.021085911 0.195375297 2.426666667 0.476190356 2.488567593 0 0 0 0 0 0 0 0 28.79735724 17.88932039 14.51010256 21.75180602 19.17749288 9.557940537 20.39533134 22.49227745 0 0 0 0 0 0 0 0 0.142701693 0.052874985 0.217656558 0.154365769 0.267867932 0.157311828 0.014114364 0.037452489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PGD2 0 0 0 0 0 0 0 0 10.13336328 2.969440994 4.77495382 7.59226575 4.698568884 5.759111111 2.488031621 1.480153404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13.14-dihydro-15-keto-PGD2 0 0 0 0 0 0 0 0 5.00106457 3.790404092 7.789175658 18.52810997 6.234857482 16.04444444 3.623917787 10.8926558 0 0 0 0 0 0 0 0 89.26710713 55.55717368 47.92717949 85.34496817 67.47198481 44.70002417 67.25249643 60.36787419 0 0 0 0 0 0 0 0 0.228576525 0.094211491 0.313466486 0.255719581 0.421709298 0.286236559 0.165385864 0.417432072 0 0 0 0 0 0 0 0 0.735920134 0.328602339 0.165495763 1.11984127 0.142804374 0.309536811 0.257245033 1.051402299 13.14-dihydro-15-keto-tetranor PGD2_PGE2 0 0 0 0 0 0 0 0 4.497006176 1.332852028 0.929657315 0.389881329 0.084675772 0.282311111 0.800894229 3.484249281 0 0 0 0 0 0 0 0 0.880920245 1.594190939 1.076020513 0.986905085 0.671961064 0.65766014 0.855940864 0.463877001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3.487481226 2.173532164 1.726346922 4.974981104 0.695318679 3.172554396 1.445995585 2.109425287 PGE1_PGD1_8-iso-PGE1_8-iso-PGA1 0 0 0 0 0 0 0 0 3.605956204 1.285787358 2.536210617 2.09163803 4.276175772 5.240888889 2.857562055 4.662642378 0 0 0 0 0 0 0 0 52.83954696 36.87993528 49.8 53.33466848 33.85816714 30.15445975 37.10942809 44.18275765 0 0 0 0 0 0 0 0 0.356613222 0.150997387 0.253697508 0.127481134 0.124685844 0.330215054 0.203526968 0.225947377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PGE2_PGD2_8-iso-PGA2 0 0 0 0 0 0 0 0 130.3393599 41.21312386 101.3337937 182.3908362 113.2624703 100.7111111 94.23026087 95.68475551 0 0 0 0 0 0 0 0 1646.682397 1105.771305 1078.148718 1321.730921 1258.39981 670.9016195 1283.480742 1345.807357 0 0 0 0 0 0 0 0 12.26924335 8.189600967 2.915340931 4.03017089 5.696288425 7.348387097 5.225546829 4.412820733 0 0 0 0 0 0 0 0 4.877780723 3.32 5.167098321 5.624300831 2.622114216 3.499111773 4.233671818 3.363678161 PGE2_13.14-dihydro-15-keto-PGE2 0 0 0 0 0 0 0 0 2.792453678 1.402236025 3.769066897 7.260646048 2.014869359 0.588266667 3.643864032 2.884548418 0 0 0 0 0 0 0 0 129.7682869 84.52211435 85.21333333 98.92797368 102.4297246 54.8116993 97.60653612 106.5644482 0 0 0 0 0 0 0 0 0.835481747 0.774023482 0.33539888 0.735477788 0.270135863 0.490645161 0.189843578 0.331275371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8-iso-PGE2 0 0 0 0 0 0 0 0 3.160804043 0.049296602 1.071799741 7.253040092 0.674251781 1.365333333 0.459078577 0.904644295 0 0 0 0 0 0 0 0 4.990184049 3.8648274 4.656512821 3.898702525 3.856780627 3.646623157 3.961955648 3.736748104 0 0 0 0 0 0 0 0 0.153982459 0.452344658 0.168533127 0.211795388 0.178410626 0.15172043 0.018025443 0.062820218 0 0 0 0 0 0 0 0 0.46401979 0.33054386 0.299357314 0.317131519 0.031648735 0.284797615 0.110007064 0.125645977 15-keto-PGE2 0 0 0 0 0 0 0 0 9.447366648 3.096564121 5.777401813 14.79054296 8.324643705 11.55555556 1.621944664 8.212464046 0 0 0 0 0 0 0 0 15.09197735 13.98106796 13.94825641 17.1877262 15.32307692 8.370219966 12.16314356 14.85189553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.174909444 1.005950292 0.220484093 0.235323507 0.279997791 0.369108793 0.102678146 0.162041379 20-hydroxy-PGE2 0 0 0 0 0 0 0 0 0.285061426 2.85687395 2.849153215 10.66050859 3.532428741 1.512 1.872847431 2.546500479 0 0 0 0 0 0 0 0 0.442614441 0.918193096 1.227123077 0.205359846 0.746842355 0.933724921 1.331272209 0.355214827 0 0 0 0 0 0 0 0 0.926291915 1.10140032 0.383239714 0.180997966 0.03686649 0.394516129 0.263432206 0.320092117 0 0 0 0 0 0 0 0 3.912783815 0.186458772 1.548802558 0.172681406 0.124449575 0.503690015 0.583381898 0.039154023 Tetranor-PGEM_Tetranor-PGDM 0 0 0 0 0 0 0 0 12.16898372 18.06895141 15.62420371 27.94428408 12.57814727 16.23111111 15.64205534 6.843720038 0 0 0 0 0 0 0 0 21.58235017 15.52108954 6.261179487 9.750318289 6.751139601 6.343872371 7.319413824 9.150744173 0 0 0 0 0 0 0 0 0.071971288 0.463093186 0.487514777 0.099624613 0.252118406 0.502043011 0.320320633 0.329677763 0 0 0 0 0 0 0 0 20.78116441 24.92426901 26.04514788 14.85279667 12.63015575 15.26507303 19.85403974 6.648275862 6-keto-PGF1a_1 0 0 0 0 0 0 0 0 81.72307692 33.0083449 68.893224 109.8147995 50.42102138 81.19111111 83.03936759 96.7033557 0 0 0 0 0 0 0 0 1255.77159 892.227616 463.9487179 1154.080538 692.8490028 290.8711627 755.1912852 428.308902 0 0 0 0 0 0 0 0 1.097195523 0.841363654 0.337322774 0.789120839 0.889911195 4.870967742 1.009877328 1.124601715 0 0 0 0 0 0 0 0 3.525611803 3.15254386 2.860879297 1.491866969 1.639829891 0.679833085 1.949980868 0.91862069 6-keto-PGF1a_2 0 0 0 0 0 0 0 0 30.1689388 13.03739861 24.75456193 36.50859107 17.74839667 26.22222222 28.1976917 28.57810163 0 0 0 0 0 0 0 0 411.2789051 314.4061489 159.5728205 406.2078535 242.8124406 98.26782693 267.546103 153.6001123 0 0 0 0 0 0 0 0 0.280750069 0.383709482 0.246001932 0.270487198 0.267615939 0.993010753 0.120349192 0.259383024 0 0 0 0 0 0 0 0 1.0905345 0.814710526 0.931245404 0.419705215 0.665613609 0.147029985 0.897548197 0.52891954 2.3-dinor-6-keto-PGF1a 0 0 0 0 0 0 0 0 5.461129702 4.259109974 9.565955978 29.75450172 0.863022565 4.330666667 0.552825929 1.612571429 0 0 0 0 0 0 0 0 2.113190184 2.73622438 1.694902564 0.799307632 1.186671415 0.303189751 2.074838542 1.00224656 0 0 0 0 0 0 0 0 0.016230202 0.008473207 0.251132316 0.410842664 0.192522201 0.179569892 0.325815538 0.261208861 0 0 0 0 0 0 0 0 6.444067497 4.116023392 2.497032774 2.068099017 0.820006628 1.307219076 1.636547461 0.441011494 6.15-diketo-13.14-dihydro-PGF1a 0 0 0 0 0 0 0 0 5.294850084 8.985955426 12.11649547 22.48320733 6.545368171 6.807111111 9.417777075 10.83535954 0 0 0 0 0 0 0 0 29.8392638 22.28106796 34.13641026 35.04510407 40.31766382 19.98660865 33.1311114 20.73484976 0 0 0 0 0 0 0 0 0.159622842 0.16006241 0.06900367 0.125701447 0.133555977 0.114301075 0.062760434 0.159532542 0 0 0 0 0 0 0 0 67.54978355 39.58274854 91.05451639 131.6205593 19.56500608 32.89323398 20.03726269 55.24597701 8-iso-PGF1a_8-iso-PGF1b 0 0 0 0 0 0 0 0 115.5009545 91.70332481 86.66102719 190.4531501 74.12826603 122.7555556 134.0597628 83.9071908 0 0 0 0 0 0 0 0 50.88107598 48.21521036 49.88512821 55.13940348 49.06695157 48.11070824 57.52198158 58.64307779 0 0 0 0 0 0 0 0 19.03629298 19.94305106 17.80243384 21.00283232 18.64743833 19.31182796 18.91971182 19.4223452 0 0 0 0 0 0 0 0 42.11962187 28.00643275 31.26266986 32.77966742 27.11962885 21.7704918 34.32376748 20.22988506 13.14-dihydro-15-keto-tetranor PGF1b_PGF1a 0 0 0 0 0 0 0 0 3.243571028 1.785061016 2.811898144 4.860206186 0.845279097 1.247111111 2.463886166 5.078995206 0 0 0 0 0 0 0 0 2.486474752 1.392734628 1.507194872 1.71829769 1.448361823 1.742658932 1.212869926 0.616731255 0 0 0 0 0 0 0 0 0.248317866 0.18363147 0.50303419 0.493263634 0.041251157 0.188709677 0.506285455 0.108420506 0 0 0 0 0 0 0 0 7.400265041 4.73245614 2.93518785 5.476870748 1.793306086 5.515850969 1.157236203 6.111264368 PGF2a 0 0 0 0 0 0 0 0 2.022944413 1.86269346 1.349779888 2.391312715 1.210005938 1.570666667 0.603741344 2.934205177 0 0 0 0 0 0 0 0 116.9598867 79.06040992 68.27282051 103.202346 68.14197531 45.62291516 88.00518739 68.71215951 0 0 0 0 0 0 0 0 1.594818323 0.845378164 0.635911145 0.596763168 0.848080455 0.705913978 0.893945609 0.863506969 0 0 0 0 0 0 0 0 0.454633802 0.222935088 0.05541295 1.209554044 0.206101845 0.338432191 0.170739367 0.083163218 2.3-dinor-8-iso-PGF2a 0 0 0 0 0 0 0 0 0.963377878 0.532267446 3.53865861 9.41313173 2.708836105 5.604444444 4.007095652 1.890776606 0 0 0 0 0 0 0 0 1.066583294 1.3099137 1.056441026 1.28516129 0.074408357 2.161571187 1.3360083 0.651693345 0 0 0 0 0 0 0 0 0.173018752 0.139342357 0.358100831 0.269225008 0.803225806 0.090129032 0.507578373 0.354098338 0 0 0 0 0 0 0 0 0.513296228 1.247912281 1.203533173 0.634890401 0.97531647 1.233595231 1.168473878 0.609655172 13.14-dihydro-15-keto-PGF2a 0 0 0 0 0 0 0 0 27.57408198 9.471158202 4.37374536 45.98561283 10.9861639 24.60444444 13.20651383 15.39996165 0 0 0 0 0 0 0 0 14.99797074 7.897087379 11.43697436 13.18406409 11.09425451 2.304017404 9.265516794 10.75900028 0 0 0 0 0 0 0 0 5.301960118 3.109302961 2.004697701 2.545836105 2.677419355 7.731182796 8.19171805 7.969780191 0 0 0 0 0 0 0 0 7.077621698 1.396438596 1.885579536 5.395313681 7.006362532 4.502533532 4.109080206 0.608551724 11b-13.14-dihydro-15-keto-PGF2a_8-iso-13.14-dihydro-15-keto-PGF2a 0 0 0 0 0 0 0 0 0.991712521 0.508007307 0.399374363 0.573336999 0.826549881 0.778222222 1.113840316 0.425647555 0 0 0 0 0 0 0 0 7.677206229 5.197572816 4.592666667 8.961934053 5.718566002 3.283084361 7.353858125 4.007587756 0 0 0 0 0 0 0 0 0.342794283 0.461668682 0.172252656 0.119024464 0.249094497 0.124516129 0.127675732 0.082516438 0 0 0 0 0 0 0 0 0.858231293 0.91324269 0.379239009 0.187204837 0.15309113 0.605219672 0.599261221 0.170813793 20-hydroxy-PGF2a 0 0 0 0 0 0 0 0 8.261785514 0.980594812 2.729936987 3.377044674 0.570748219 2.382222222 0.232006324 0.710473634 0 0 0 0 0 0 0 0 1.111628126 0.334014563 0.515025641 1.182101423 1.072378917 0.600280396 1.824686811 1.130440887 0 0 0 0 0 0 0 0 0.071125231 0.290339743 1.862329534 0.227825194 2.542603416 0.06872043 0.161722594 1.27808617 0 0 0 0 0 0 0 0 23.63802456 13.04216374 23.412502 29.31349206 11.21641445 23.0371386 14.09595291 26.68505747 Tetranor-PGFM 0 0 0 0 0 0 0 0 5.203880966 3.86512532 5.281049633 8.229644903 1.711751781 6.179555556 4.681068775 2.44591371 0 0 0 0 0 0 0 0 3.913025012 1.968899676 1.032179487 1.616187683 1.655270655 0.950176456 1.276591882 1.84786296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.626610125 3.509298246 3.065227818 2.369232804 2.537766486 2.012780924 3.061044886 0.74445977 8-iso-15-keto-PGF2b 0 0 0 0 0 0 0 0 7.249940483 0.83697479 3.329457057 3.777117984 0.693473872 7.392888889 4.340932806 3.705794823 0 0 0 0 0 0 0 0 3.338017933 2.494476807 2.397210256 2.761719476 5.336277303 1.790408509 2.180324212 2.108447065 0 0 0 0 0 0 0 0 1.060674043 0.316110309 0.491747344 0.196522896 0.062872106 0.280752688 0.071670799 0.140475364 0 0 0 0 0 0 0 0 1.485039314 1.210780702 0.752904876 1.67223356 0.940660555 0.810060209 1.317006623 1.311448276 8-iso-PGF3a 0 0 0 0 0 0 0 0 1.748545761 0.405823602 2.333313768 12.31556472 1.368218527 2.856 0.344860079 0.618863279 0 0 0 0 0 0 0 0 2.4292874 2.084848975 1.244574359 1.336928689 1.273376068 2.025143824 1.688201271 0.526295984 0 0 0 0 0 0 0 0 0.211655376 0.033229785 0.199956732 0.145530443 0.048747932 0.087354839 0.096322451 0.194679911 0 0 0 0 0 0 0 0 0.263599611 0.278608187 0.137178897 0.857917611 0.227188777 0.709520119 1.427428992 0.356045977 15d-PGJ2 0 0 0 0 0 0 0 0 114.3079169 32.31935696 67.57496763 114.1501947 50.22387173 65.06666667 67.35532016 58.33395973 0 0 0 0 0 0 0 0 1083.426144 700.1725998 792.1179487 881.9454975 818.9648623 478.6995407 842.5936973 829.7669194 0 0 0 0 0 0 0 0 6.810762598 4.12847057 2.304825188 4.764765145 3.337639469 5.449462366 4.502589732 4.817928403 0 0 0 0 0 0 0 0 0.462553229 0.308459064 2.43997442 2.336923658 0.229389153 5.812721311 3.102575423 0.964965517 TXB2 0 0 0 0 0 0 0 0 38.07281303 12.77538911 22.29572723 54.51949599 18.96579572 17.85777778 14.25631621 16.54588686 0 0 0 0 0 0 0 0 179.0825861 99.83279396 92.23641026 97.97811315 169.4287749 61.99419869 154.8271301 102.4156136 0 0 0 0 0 0 0 0 12.5865149 8.251761126 8.272744833 9.96119908 9.938580645 10.33655914 11.33458817 8.056507467 0 0 0 0 0 0 0 0 0.632674265 0.37155848 0.925141487 0.282156085 0.049801834 0.781362742 0.070553054 0.198804598 11-dehydro-TXB2 0 0 0 0 0 0 0 0 1.291463223 1.514317866 6.694449719 10.16764261 10.66086698 3.904 0.84971004 5.562193672 0 0 0 0 0 0 0 0 1.493138273 0.46021575 0.395165128 0.190731993 1.005379867 0.62876964 0.926121126 0.61067116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.968417705 0.053173392 0.120751399 0.343480726 0.467579808 0.033961967 0.17315791 0.584643678 iPF2a-IV 0 0 0 0 0 0 0 0 8.6196968 3.729268542 7.250410013 14.90006873 6.072209026 12.13333333 5.360290909 10.46611697 0 0 0 0 0 0 0 0 3.807659273 1.424967638 1.956246154 1.079041556 1.265493827 6.504375151 4.183260278 4.866722831 0 0 0 0 0 0 0 0 4.857779949 2.443671256 1.900807417 1.411127797 2.08397723 7.104301075 9.207736743 4.95258391 0 0 0 0 0 0 0 0 8.180475307 2.725409357 1.962807354 6.662585034 9.236076439 5.990843517 5.269492274 1.266758621 15-HpETE 0 0 0 0 0 0 0 0 12.22117911 4.196033613 6.505308589 33.23802978 7.900771971 13.28888889 5.106238735 8.798159156 0 0 0 0 0 0 0 0 2.046602171 0.564525351 0.153358462 1.369223947 1.419985755 0.723065023 0.853357541 1.511760741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4.30875519 2.579795322 1.981915268 0.565253212 0.528456865 0.320817884 0.484197204 0.132524138 5-oxo-ETE 0 0 0 0 0 0 0 0 55.14070747 25.15291195 34.61282693 141.8206644 50.32244656 79.52888889 19.34785771 58.90055609 0 0 0 0 0 0 0 0 3.699159981 3.174056095 3.549846154 3.018181818 2.310679012 2.787933285 2.662544417 3.850025274 0 0 0 0 0 0 0 0 0.399057105 0.33592386 0.572294379 0.493011196 0.61120759 0.739032258 0.504022847 1.166253631 0 0 0 0 0 0 0 0 29.32827988 13.91099415 13.75769784 4.309977324 1.626260908 1.750347541 3.884326711 0.396505747 12-oxo-ETE 0 0 0 0 0 0 0 0 13.87651881 7.151888929 7.485403539 27.7313173 11.345962 13.41333333 7.381160474 9.944084372 0 0 0 0 0 0 0 0 0.993728174 0.643764833 1.099430769 0.679625206 0.458746439 0.738714044 0.840440929 0.626986801 0 0 0 0 0 0 0 0 1.222271019 0.916603347 0.60487232 0.856395537 0.570132827 0.160860215 0.365896021 0.339833984 0 0 0 0 0 0 0 0 5.95423624 2.834619883 2.371504396 0.398688587 0.358844582 0.440951416 1.034110375 0.063816092 5-HETE 0 0 0 0 0 0 0 0 14.83840539 5.031552795 9.583150626 24.50639175 11.6219715 19.65333333 3.397160474 11.74573346 0 0 0 0 0 0 0 0 1.338419066 2.286752967 0.995148718 3.349683141 2.033618234 2.168793812 3.598998833 3.489682673 0 0 0 0 0 0 0 0 0.394685808 0.173012443 0.207908828 0.25824396 0.658456167 0.29655914 0.246947491 0.82105625 0 0 0 0 0 0 0 0 5.760650234 2.15994152 3.779120703 1.174108088 1.866651939 1.211033085 1.204629875 0.860505747 8-HETE 0 0 0 0 0 0 0 0 5.331386861 1.398354403 3.200497195 11.90180069 3.458004751 0.115555556 0.044921043 6.843720038 0 0 0 0 0 0 0 0 0.945941482 0.436488673 1.069635897 0.700522137 0.438646724 1.19173314 0.489109065 0.827902275 0 0 0 0 0 0 0 0 0.113710123 0.080497406 0.168533127 0.186425381 0.159637192 0.250645161 0.142975271 0.225490917 0 0 0 0 0 0 0 0 2.101874724 1.633546784 2.049323741 0.977116402 0.812855407 0.556137109 0.766360559 0.860321839 11-HETE 0 0 0 0 0 0 0 0 8.388545761 4.661828279 9.669123867 20.14057274 10.31585511 15.04 4.059585771 15.4063279 0 0 0 0 0 0 0 0 170.4261444 89.13322546 46.69282051 105.2920392 87.25641026 52.16340343 93.04266632 83.30300477 0 0 0 0 0 0 0 0 1.006244346 0.924373367 0.924110489 0.753653316 1.215359393 0.829677419 0.830377101 1.25069861 0 0 0 0 0 0 0 0 5.00683806 3.273888889 5.774836131 2.608257748 2.075687617 2.361108793 2.618866814 2.282298851 12-HETE 0 0 0 0 0 0 0 0 28.37192588 23.42559006 35.54706949 36.37168385 18.7834323 25.10222222 14.1198419 33.09177373 0 0 0 0 0 0 0 0 37.30887211 13.38117584 14.62502564 11.63104213 14.2668566 13.44210781 19.77533394 19.2244875 0 0 0 0 0 0 0 0 31.9809722 26.8713188 43.24914043 20.81350391 34.13237192 17.02150538 23.8004803 17.66497671 0 0 0 0 0 0 0 0 168.4198251 84.84444444 137.630056 79.29856387 0.047968187 9.248500745 16.56579838 4.704367816 15-HETE 0 0 0 0 0 0 0 0 10.78207748 4.885991962 10.64348727 25.11486827 11.23752969 22.08 6.801669565 20.74761266 0 0 0 0 0 0 0 0 59.81170363 34.47588997 19.87317949 39.6139332 37.85446344 18.1649021 38.70247698 34.1789385 0 0 0 0 0 0 0 0 0.736634033 0.373219956 0.338861889 0.603831429 0.731155977 0.376021505 0.501544752 0.860311753 0 0 0 0 0 0 0 0 6.379538829 3.965555556 5.021135092 3.59164777 1.842814537 4.680655738 0.063859308 2.354022989 20-HETE 0 0 0 0 0 0 0 0 7.538506457 3.478418707 4.487230039 26.6816953 10.27149644 12.62222222 8.195807115 6.563604986 0 0 0 0 0 0 0 0 4.26946673 1.289320388 0.959820513 0.043375381 1.183124406 1.589780034 1.106523149 0.218443134 0 0 0 0 0 0 0 0 2.696103124 2.307695908 1.591701758 1.296268557 1.304060721 2.240860215 1.710962549 2.518514445 0 0 0 0 0 0 0 0 11.54476544 3.004502924 3.426155076 2.7280839 0.81890644 0.766321311 1.40519794 1.209931034 5(S)-HETrE 0 0 0 0 0 0 0 0 4.567097136 1.631736938 2.443932672 3.259912944 0.266398456 0.800088889 0.135529486 1.364287632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12(S)-HETrE 0 0 0 0 0 0 0 0 5.369414935 3.554595543 6.665791972 5.827683849 13.9976247 1.592888889 9.062943874 2.660456376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15(S)-HETrE 0 0 0 0 0 0 0 0 5.027907917 2.525480453 3.828101856 6.302295533 3.244097387 4.995555556 0.940727905 7.601303931 0 0 0 0 0 0 0 0 25.11151487 12.06947141 8.474512821 17.14973178 11.21642925 9.537877689 12.49897549 14.57686043 0 0 0 0 0 0 0 0 0.181479326 0.059583103 0.306796987 0.2558458 0.377862619 0.096946237 0.173035633 0.136823689 0 0 0 0 0 0 0 0 3.264564007 1.998552632 1.384792966 5.025170068 0.411103502 4.59357377 0.603169978 4.377011494 5.15-DiHETE 0 0 0 0 0 0 0 0 2.084087591 0.692384362 0.98468019 4.994071019 1.257814727 4.151111111 0.567418182 2.17598466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.075868893 0.190535965 0.351638689 0.361046863 0.099108583 0.028301639 0 0.099402299 5(6)-EET 0 0 0 0 0 0 0 0 1.665778776 1.531299963 1.744110488 4.738510882 1.650635392 1.241777778 1.122238735 1.007777565 0 0 0 0 0 0 0 0 0.490009438 0.550199569 0.613348718 0.513399614 0.24115717 1.093826444 0.674677733 0.724880652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.216266455 1.632818713 0.772543565 0.404021164 0.343258588 0.276485246 0.508382634 0.084413793 8(9)-EET 0 0 0 0 0 0 0 0 3.526917462 1.667641944 1.298769098 2.44455441 3.285991686 1.042666667 1.119089328 0.658906999 0 0 0 0 0 0 0 0 0.244338839 0.534530744 0.395335385 1.560620843 0.832758784 1.036847957 1.335147192 0.797135636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.848845304 0.654049708 1.156559552 0.423783069 0.318687728 0.340015499 0.282163355 0.191816092 11(12)-EET 0 0 0 0 0 0 0 0 2.05948119 3.277544757 3.459563228 10.16460023 5.421615202 5.368 3.889517787 3.102274209 0 0 0 0 0 0 0 0 2.054044361 1.111591154 1.218184615 1.424315857 2.284273504 1.487860769 2.082157956 0.848879528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.994716848 2.473011696 2.321346123 1.149954649 0.877583122 0.806893592 1.440621045 0.305103448 14(15)-EET 0 0 0 0 0 0 0 0 2.538933184 1.798646693 2.361971515 5.681649485 0.972440618 2.982222222 0.313261028 1.990090125 0 0 0 0 0 0 0 0 1.200934403 0.995194175 0.878523077 0.316351048 1.431020893 0.981073241 0.836135391 0.613001966 0 0 0 0 0 0 0 0 1.861326424 1.412848617 2.249673556 1.693858232 2.242732448 0.826344086 1.369416499 0.782827779 0 0 0 0 0 0 0 0 10.68829402 6.841432749 8.335827338 4.884013605 0.570447366 0.57454307 0.731181751 0.327172414 12-HHT 0 0 0 0 0 0 0 0 7.357313869 3.325579832 4.047047044 11.03015808 5.224465558 7.121777778 2.720037945 5.644318313 0 0 0 0 0 0 0 0 120.4067957 115.6359223 70.99692308 132.6955153 101.5626781 54.7715736 131.2758397 106.7509127 0 0 0 0 0 0 0 0 1.833124509 2.196325623 0.978107784 1.941247363 2.024759013 2.148387097 2.311092361 1.699169918 0 0 0 0 0 0 0 0 3.378955738 1.455169591 1.555702638 1.42505291 0.511770684 1.409342474 0.660335541 0.513471264 PGE3_PGD3 0 0 0 0 0 0 0 0 0.543055811 0.585154549 0.812160552 0.228178694 1.987761283 2.410666667 1.152683004 0.752490892 0 0 0 0 0 0 0 0 12.71047664 4.285199569 6.401641026 8.363521923 4.638698955 4.313512207 5.343172092 5.668520079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PGF3a 0 0 0 0 0 0 0 0 2.451692308 1.707913774 0.33466517 0.297240779 1.177969121 0.528444444 0.4159317 0.71874976 0 0 0 0 0 0 0 0 2.773978292 1.552108954 0.886184615 0.50627566 0.600626781 1.060923374 1.297689016 1.815231676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5-HEPE 0 0 0 0 0 0 0 0 3.869170129 1.373123858 0.867756582 6.776907216 1.72111639 5.308444444 1.269211067 2.708839885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.673639014 0.902078947 0.885333333 0.23626455 0.11711499 0.046489896 0.330534216 0.097508046 8-HEPE 0 0 0 0 0 0 0 0 6.207523863 3.223687249 6.723107467 18.43683849 5.860273159 10.24888889 1.426681423 6.990143816 0 0 0 0 0 0 0 0 0.326359604 0.080492988 0.864051282 0.54237036 0.37874169 0.911254532 0.645400078 0.490867734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3.534411167 2.196830409 1.819232614 0.377358277 0.556695018 0.083717437 1.081015453 0.099126437 12-HEPE 0 0 0 0 0 0 0 0 1.812671533 1.101895506 1.858168321 3.716270332 0.994127078 2.233777778 1.792012648 1.285982742 0 0 0 0 0 0 0 0 1.693685701 0.564525351 0.978548718 0.338340319 0.756301045 0.482310853 0.482220205 0.840022466 0 0 0 0 0 0 0 0 1.675193782 1.207202091 2.486953834 1.624437812 1.614011385 0.69655914 1.358642176 0.958678743 0 0 0 0 0 0 0 0 14.10244721 6.894824561 12.42279776 9.065381708 0.81615597 1.175606557 1.454301692 0.195678161 15-HEPE 0 0 0 0 0 0 0 0 23.10764739 6.744318597 12.76416055 39.74872852 14.17505938 25.60888889 4.651674308 14.98615532 0 0 0 0 0 0 0 0 2.946323738 2.441202805 1.456969231 1.386321436 3.107179487 2.344143099 1.833297886 1.959275484 0 0 0 0 0 0 0 0 0.106194313 0.245791629 0.084997643 0.187561351 0.127760152 0.15172043 0.198786266 0.304800729 0 0 0 0 0 0 0 0 9.664634685 6.135204678 5.148521183 2.909391534 1.016940241 0.825497466 1.60259014 0.145177011 18-HEPE 0 0 0 0 0 0 0 0 0.655797866 0.061863354 1.110201122 0.757705384 0.928574822 1.148444444 0.368690593 2.030834132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.977022705 0.406505848 0.976361311 0.618265306 0.325655584 0.7617693 0.410419426 0.368367816 15-oxo-ETE 0 0 0 0 0 0 0 0 4.814652442 0.211985093 2.846860596 0.267577549 4.011009501 7.124444444 0.055838988 5.453330777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.817263009 1.225827485 1.025192646 0.330619803 0.408169668 0.071525961 0.192115379 0.19862069 19(20)-EpDTE 0 0 0 0 0 0 0 0 0.537314318 0.365551772 2.581489858 7.125260023 1.136074822 1.558222222 0.341710672 1.122370086 0 0 0 0 0 0 0 0 0.594983483 0.483942826 0.689964103 0.170974894 0.155989554 0.28232439 0.367219297 0.511378826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.778351444 0.655748538 0.422231815 0.734640967 0.594651497 0.748509091 0.921977925 0.925977011 MaR2 0 0 0 0 0 0 0 0 1.632224593 1.158664231 3.676788951 4.35973425 3.323942993 4.254222222 1.122238735 7.747727709 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 MCTR2 0 0 0 0 0 0 0 0 19.46888265 15.83216661 22.50779456 166.5704467 11.93741093 33.15555556 42.55898814 10.69530201 0 0 0 0 0 0 0 0 15.5541765 8.37162891 6.627230769 5.366711966 9.710921178 5.449069374 15.12535339 13.09912946 0 0 0 0 0 0 0 0 2.741226189 1.649834224 2.506192776 2.401946509 2.485905123 1.915053763 1.483624327 0.746881606 0 0 0 0 0 0 0 0 1.340729746 1.147681287 2.011373301 2.994399093 0.624539932 4.484721311 3.190522443 1.294712644 PD1 0 0 0 0 0 0 0 0 6.042735542 0.195294118 1.441484678 2.856797251 1.346039192 1.399111111 1.22196996 0.04004372 0 0 0 0 0 0 0 0 1.930268995 0.813435814 0.440964103 0.610285387 1.404221273 0.121741358 2.049866425 0.034090368 0 0 0 0 0 0 0 0 0.430079212 0.595313024 0.449934711 0.174687019 0.232085009 0.232365591 0.354798468 0.198217471 0 0 0 0 0 0 0 0 2.293994169 1.341105263 1.371788969 1.262879819 1.165832321 0.869632191 0.806181015 0.745563218 RvD2 0 0 0 0 0 0 0 0 5.330641213 2.835039825 2.749424256 11.50324857 7.388182898 1.440888889 0.782417708 3.844579099 0 0 0 0 0 0 0 0 351.3496933 175.4012945 85.04307692 122.7694729 26.58679962 25.17887358 16.89492932 11.77057006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29.97649969 20.23549708 23.18426859 38.1749811 6.606627637 11.51263189 5.533333333 12.45609195 RvD3 0 0 0 0 0 0 0 0 0.447165413 1.142652539 0.679188606 5.143147766 0.637286223 0.391555556 0.731502292 0.627903356 0 0 0 0 0 0 0 0 4.355639453 0.29860302 0.413723077 2.562723696 0.354779677 0.814952864 0.767677344 0.854939624 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4-HDoHE 0 0 0 0 0 0 0 0 4.804959012 1.977686518 2.168245145 7.234785796 3.92574228 5.790222222 0.19463336 3.569557047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.18345346 0.337607364 0.069991269 0.250039729 0.222635294 0.213010753 0.19059778 0.406477048 0 0 0 0 0 0 0 0 16.41081368 7.004035088 10.05553957 3.065291005 1.570334696 0.405524888 1.07588521 0.653609195 7-HDoHE 0 0 0 0 0 0 0 0 0.987984278 0.745756668 0.737077255 2.366973654 0.371479216 0.746844444 0.706412016 0.429594631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.986702005 0.786315789 1.152047962 0.421900983 0.381215067 0.170423368 0.052841501 0.094675862 8-HDoHE 0 0 0 0 0 0 0 0 0.9022347 0.952453051 1.264379801 5.001676976 1.402226841 1.482666667 0.549361581 1.472513902 0 0 0 0 0 0 0 0 2.94005663 1.354681769 1.669789744 0.678200415 1.282046534 1.876277496 2.682780444 0.471755125 0 0 0 0 0 0 0 0 0.999898915 0.536649374 0.878065289 0.497050202 0.707594687 0.329247312 0.407592653 0.261779435 0 0 0 0 0 0 0 0 5.25615337 3.419502924 3.460655476 2.747532124 0.552294267 0.416212221 1.178490066 0.485701149 10-HDoHE 0 0 0 0 0 0 0 0 2.55086356 0.932074534 2.792410876 5.266364261 2.205611639 5.128 3.401359684 1.924517737 0 0 0 0 0 0 0 0 1.416757905 0.921326861 0.927471795 1.484632001 1.084202279 0.37152381 0.579955907 0.546340915 0 0 0 0 0 0 0 0 0.607892289 0.329448843 0.568446591 0.243981219 0.56206907 0.377741935 0.304374635 0.238956468 0 0 0 0 0 0 0 0 6.784309568 3.135555556 4.017969624 3.042078609 1.062231305 0.818174665 1.686628403 1.166528736 11-HDoHE 0 0 0 0 0 0 0 0 0.399369343 0.237846401 0.696956409 1.603335624 0.708752969 1.531555556 0 0.46607325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.847378744 0.609880117 0.570052758 0.225254346 0.306035568 0.223048584 0.051888742 0.111632184 13-HDoHE 0 0 0 0 0 0 0 0 1.603889949 0.354100986 1.052312473 5.334817869 2.119851544 1.102222222 0.869656285 0.933292426 0 0 0 0 0 0 0 0 12.82406796 6.285436893 3.132292308 6.373564123 4.47317189 3.281078076 4.688730385 3.572659365 0 0 0 0 0 0 0 0 0.326296163 0.212510044 0.332320649 0.214572205 0.21545351 0.18688172 0.164416174 0.171742829 0 0 0 0 0 0 0 0 4.801519569 2.669590643 4.163932854 1.064319728 0.992186016 1.155419374 0.634440029 0.728643678 16-HDoHE_16(17)-EpDPE 0 0 0 0 0 0 0 0 4.698331275 1.255219583 3.411418213 7.208925544 2.777345606 4.340444444 1.891743874 2.249833174 0 0 0 0 0 0 0 0 0.867602643 0.702411003 0.859794872 1.077616766 0.249039411 0.531264201 0.707830372 0.958893569 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4.657796625 2.744824561 3.699504396 0.955472411 1.906992157 2.454128167 1.071487859 2.716321839 17-HDoHE 0 0 0 0 0 0 0 0 0.829161145 0.396944392 0.896414329 1.556178694 1.765475059 0.999111111 0.703262609 1.019236817 0 0 0 0 0 0 0 0 1.816285984 0.781650485 0.847876923 1.269013661 0.267523267 1.299270002 1.217175464 0.549604044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.174909444 0.962751462 2.613007194 0.099342782 0.279264332 0.275099851 0.194191906 0.494528736 20-HDoHE 0 0 0 0 0 0 0 0 3.383007299 2.41485422 1.653552007 4.520980527 2.158295724 3.201777778 0.378138814 1.109637584 0 0 0 0 0 0 0 0 0.651387447 0.672864078 0.290712821 1.539723911 0.557274454 0.575001209 0.2310782 0.668008986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6.713914657 2.266239766 3.659696243 1.152464097 1.483053132 1.654359463 0.932238411 1.349701149 19(20)-EpDPE 0 0 0 0 0 0 0 0 0.804554745 0.915092437 0.388312473 0.880769759 0.814228029 1.172444444 1.596749407 0.516684947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3.862920753 2.264055556 3.12361311 2.271991686 2.594609522 1.835450373 2.591994113 0.784367816 9.10-DiHOME 0 0 0 0 0 0 0 0 30.45974172 9.78168798 5.320597324 15.7443299 10.42921615 5.109333333 9.054545455 4.608529243 0 0 0 0 0 0 0 0 10.60707881 8.917799353 8.134 8.002574923 8.004415954 6.211457578 11.37953573 15.43925864 0 0 0 0 0 0 0 0 0.377764658 0.373349456 0.178537377 0.354927671 0.307934725 0.165483871 0.257721815 0.453606476 0 0 0 0 0 0 0 0 78.40233236 34.24356725 43.76243006 23.72996977 45.78614824 13.83811624 33.9084621 11.5383908 12.13-DiHOME 0 0 0 0 0 0 0 0 72.62616508 6.157223237 12.08783772 20.14057274 18.28562945 10.88888889 16.25094071 8.887286673 0 0 0 0 0 0 0 0 52.60453044 14.03478964 25.32989744 19.23467563 23.63884141 10.74164854 19.91741668 15.52782926 0 0 0 0 0 0 0 0 1.100579753 2.811452198 4.278740583 2.211355903 1.724888046 1.479569892 1.485779191 1.577067042 0 0 0 0 0 0 0 0 183.965368 59.60467836 94.42494005 60.44633409 143.7945432 34.15988077 90.09683591 33.56321839 9-HODE 0 0 0 0 0 0 0 0 129.7428411 28.12720497 88.15123004 189.5404353 73.29038005 136.5333333 34.69596838 86.19904123 0 0 0 0 0 0 0 0 316.8022652 195.9050701 121.3502564 255.037551 131.0422602 183.6553058 175.2784334 184.2269026 0 0 0 0 0 0 0 0 7.601826329 7.953910364 10.35824609 6.812036421 7.171703985 5.946236559 7.934211722 10.12997405 0 0 0 0 0 0 0 0 180.1816415 50.91637427 79.00591527 31.34614512 28.89826577 19.72802385 19.46805004 15.05287356 13-HODE 0 0 0 0 0 0 0 0 160.9109489 53.80898794 110.7335347 232.2859107 87.14014252 155.6444444 77.97932016 132.8 0 0 0 0 0 0 0 0 260.0849457 154.4946063 102.4092308 138.0147343 107.3561254 141.7239546 142.5132927 127.634934 0 0 0 0 0 0 0 0 13.19849646 9.579139525 13.58269268 9.927119965 12.3236888 8.808602151 10.48880379 11.91358895 0 0 0 0 0 0 0 0 263.5116176 105.3274854 130.8892086 57.02721088 42.48558489 41.6014307 39.0142752 29.48045977 9-Oxo-ODE 0 0 0 0 0 0 0 0 64.05120719 39.81573986 61.32757877 146.5363574 59.58847981 102.3111111 3.843326482 71.93863854 0 0 0 0 0 0 0 0 11.73124115 16.15679612 14.31005128 12.02523425 9.553276353 14.21252115 10.47967838 8.516764954 0 0 0 0 0 0 0 0 2.122194143 2.161360534 2.2022175 1.808717471 2.269191651 1.784946237 1.367261634 2.646323062 0 0 0 0 0 0 0 0 512.1229791 265.0175439 240.4147082 117.2853364 67.34982879 96.50265276 105.3165563 23.41149425 13-Oxo-ODE 0 0 0 0 0 0 0 0 26.64947782 12.94521008 29.76966767 83.77200458 25.44709026 57.06666667 27.66229249 33.50558006 0 0 0 0 0 0 0 0 12.96116092 10.5070658 9.615230769 10.02577784 8.347293447 15.25578922 8.369964985 8.269699523 0 0 0 0 0 0 0 0 2.054509546 2.263665796 1.690461657 1.782211493 1.43887666 1.989247312 1.659245797 2.421516834 0 0 0 0 0 0 0 0 209.2782048 145.0073099 121.3883293 71.11148904 33.02396995 49.20131148 66.54657837 11.41333333 15-HEDE 0 0 0 0 0 0 0 0 1.817891072 1.502673 1.619735865 4.703523482 1.360332542 3.272888889 3.00138498 2.684011505 0 0 0 0 0 0 0 0 0.864469089 0.765533981 0.351068718 0.286050497 0.514316239 0.717848683 0.163524316 0.133322101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10.35978443 5.108625731 5.652757794 2.85606576 2.777974152 0.6873538 4.082207506 0.393747126 13-HoTrE 0 0 0 0 0 0 0 0 3.933295901 0.259680526 2.991295641 8.769667812 3.27317696 5.597333333 2.451288538 3.721710451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PGD2_1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 66.1571496 43.20566343 43.1174359 62.88076675 49.89458689 26.75180082 58.38308909 56.07919124 0 0 0 0 0 0 0 0 0.360984519 0.330873347 0.441213058 0.162696219 0.537247818 0.210860215 0.092766924 0.131346177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PGD2_2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 65.02123643 43.14298813 48.82102564 60.74358057 52.57454891 30.63596809 52.87200104 53.84161752 0 0 0 0 0 0 0 0 0.725212258 0.173789445 0.44390651 0.278943867 0.188490323 0.226021505 0.200941131 0.46809906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PGE2-EA_PGD2-EA 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.578914582 0.546170442 1.45654359 0.083872684 0.181330959 0.32220933 1.202536636 0.229584386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.836819507 0.271327485 0.188823341 0.420646259 0.023654037 0.039325425 0.042629875 0.198804598 15-keto-PGF2a_8-iso-15-keto-PGF2a 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.695644172 1.336326861 2.541502564 2.277290609 4.232763533 1.020396423 1.912950331 1.385431059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20-carboxy-AA 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4.578905144 3.347308522 1.834087179 2.190378371 0.950204179 0.408880832 1.417382959 1.555579893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4.264758371 3.44619883 2.903341327 2.623628118 1.351397327 1.260313562 1.135005151 1.257931034 5(S)-HETrE_1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.141127419 0.265250809 0.383417436 0.684374508 0.395688509 1.229050036 1.31878615 0.587829261 0 0 0 0 0 0 0 0 0.403569411 0.354053906 0.608848368 0.384462904 0.389202277 0.380645161 0.28788992 0.559619159 0 0 0 0 0 0 0 0 1.699743794 1.075602339 1.119139888 1.132702192 0.392767039 0.082925782 0.205014275 0.50537931 8(S)-HETrE_2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.528777725 3.238969795 1.609348718 1.309857664 4.611111111 0.668895335 8.718713526 25.56894131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.317363725 0.507464912 0.096654197 1.613888889 1.397421849 0.184890849 1.271567329 0.808643678 12(S)-HETrE_1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.763798962 0.86268069 0.745723077 0.611235248 0.98488604 0.723065023 0.761649591 0.440429093 0 0 0 0 0 0 0 0 1.143023636 1.193345555 1.098287039 0.932379341 0.584496395 0.406989247 0.54345687 0.390615086 0 0 0 0 0 0 0 0 6.185952823 3.827222222 4.556706635 3.277966742 1.057097095 2.2225693 1.099093451 2.092873563 17.18-DiHETE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.356828693 1.380199569 2.115861538 1.210122309 1.797545109 0.592656514 1.579271171 1.296394271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4.789787084 3.997105263 3.179344524 2.131776266 2.279222357 0.911787779 1.707149375 1.102712644 11.12-DiHETrE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.429683813 1.259773463 0.578446154 1.493655676 1.762075024 1.027217791 1.621465439 1.306649817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5.235621521 6.902105263 2.579568345 2.356371882 1.624977356 1.40023845 1.814640177 1.332781609 LXA5_1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.156795186 0.523786408 0.563548718 0.770336886 0.182631529 0.505985013 0.786621709 0.285523729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RvE2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4.578905144 0.845668824 2.233764103 0.691498462 1.358504274 1.389151559 2.305184801 1.927576523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 MaR2_1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.379542237 6.85399137 3.676261538 6.045862242 6.695963913 6.343872371 6.979276358 2.772726762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 MCTR3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.058357716 0.59004315 0.311271282 0.59651241 0.337320513 0.262743051 0.231207366 0.592490873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.084268575 0.517172515 0.717077538 0.391787604 0.043934165 0.164208882 0.362781457 0.032 RvD1_1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.551887683 3.508921251 3.431092308 2.130062227 3.221866097 2.522301184 1.663229153 1.866043246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13-HoTrE_1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.2538084 1.529277238 1.545502564 1.88214863 1.634382716 2.096166304 0.394042796 0.636776186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12.14312218 1.817748538 4.660207834 1.868911565 1.87582017 0.889225633 1.383455482 1.058758621 13-HoTrE_2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3.695243039 3.468182309 3.670728205 2.102516272 1.909867047 3.606096205 2.592364155 2.372760461 0 0 0 0 0 0 0 0 0.305849774 0.008202551 0.234202048 0.180240652 0.165937002 0.101989247 0.24156033 0.104746009 0 0 0 0 0 0 0 0 3.516812439 1.157388889 1.79216307 0.965196523 1.302438971 0.629760954 0.760741722 0.35291954 18-carboxy-dinor-LTB4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.274545648 0.109855131 0.427104501 0.360859962 0.1527074 0.233333333 0.294570001 0.16443948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12(S)-HETrE_2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.254945316 0.131313336 0.178793896 0.294973673 0.272781784 0.077430108 0.130261569 0.142415316 0 0 0 0 0 0 0 0 2.048785228 1.316836257 1.12577458 1.215200302 0.059758533 0.706551416 0.291935247 0.677517241 LXA4_1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.175693966 0.382964912 0.423293365 0.461111111 0.227922236 0.553564232 0.017990052 0.127190805 16-HETE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.369866596 0.393400585 0.328815348 0.395551776 0.099108583 0.463513562 0.264085357 0.295908046 17-HETE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.610382543 0.480526316 0.268572342 0.207186319 0.400101624 0.16636614 0.176016188 0.066593103 18-HETE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.404477427 0.465722222 0.573768185 0.450759637 0.415504253 0.320817884 0.352032377 0.302896552 5.6-DiHETE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.255885502 0.467906433 0.395958433 0.138333333 0.198217166 0.064420864 0.176016188 0.231908046 14.15-DiHETE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.906921106 1.755862573 1.556764189 0.319954649 0.870615266 0.137411386 0.482242826 0.280827586 5.6-DiHETrE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.26828165 0.675891813 0.678596323 0.193196145 0.407252844 0.228788077 0.070430905 0.198804598 8.9-DiHETrE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.150564538 1.676745614 2.325326938 0.875170068 0.557611841 0.792841729 0.743396615 0.34262069 LTB5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.873776835 0.754766082 0.434970424 0.172744142 0.231589528 0.186988733 0.0277766 0.224551724 LXA5_2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.641180316 0.734865497 0.303868905 0.518514739 0.097733348 0.212757079 0.237652391 0.032091954 RvE3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.091044085 0.139522515 0.163346123 0.919712774 0.497468243 0.390285544 0.40015894 0.056735632 14-HDoHE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.11810584 0.801847953 1.036869704 0.562430083 0.083797636 0.412253949 0.440956586 0.147622989 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name PubChem d5.EPA 24778482 LPC170 24779463 FA120 3893 FA130 12530 FA140 11005 FA141 757 FA150 13849 FA151 5282742 FA160 985 FA161 445638 FA170 10465 FA180 5281 FA181 445639 FA182 5280450 FA183 860 FA200 10467 FA201 5312518 FA202 6439848 AA 444899 EPA 446284 DPA_n.3_n.6 5497182 DHA 445580 LPA151 138289423 LPA160 91885979 LPA161 87978917 LPA170 17786744 LPA180 9547179 LPA181 5311263 LPA182 20835023 LPA183 20833812 LPA200 17786819 LPA201 87981051 LPA202 87977098 LPA204 131821847 LPA205 25006224 LPA225 25099711 LPA226 25099673 LPC140 460604 LPC150 24779458 LPC160 10097314 LPC161 24779461 LPC180 497299 LPC181 16081932 LPC182 11005824 LPC183 24779469 LPC200 24779474 LPC201 52924051 LPC202 52924053 LPC203 53480467 LPC204 53480469 LPC205 11757087 LPC225 138126796 LPE140 24802348 LPE150 75958077 LPE160 139292086 LPE161 25244429 LPE170 75958076 LPE180 45479288 LPE181 71571631 LPE182 52925130 LPE183 139292035 LPE200 75958060 LPE201 138184141 LPE202 138244438 LPE203 138270216 LPE204 138187816 LPE205 138192172 LPE225 138230638 LPE226 138295358 LPG140 45479384 LPG160 3300276 LPG161 138188744 LPG170 75960341 LPG180 10029397 LPG181 25244390 LPG182 25245761 LPG200 75960324 LPG201 138147046 LPG202 138119475 LPG203 138145535 LPG204 138174866 LPG225 138259956 LPG226 138209914 LPI160 74819149 LPI161 138282068 LPI170 75961490 LPI180 74819151 LPI181 138270730 LPI182 138258356 LPI200 75961473 LPI201 138313825 LPI202 138309679 LPI203 138128582 LPI204 138124432 LPI205 23427592 LPI225 138154068 LPI226 138132704 LPS130 74819134 LPS150 78184051 LPS160 4575781 LPS170 75959206 LPS180 74819135 LPS181 138191247 LPS182 138169711 LPS200 75959188 LPS201 138290881 LPS202 138314093 LPS203 138247595 LPS204 138297252 LPS225 138171185 LPS226 138157662 d5-EPA 24778482 d4-PGE2_d4-PGD2 5283031 LTB4 5280492 20-hydroxy-LTB4 5280745 LTC4 5280493 LTD4 5280878 LXA4_2 5280914 LXB4 5280915 PGA2_PGJ2_12-HpEPE 5280880 PGB2_13.14-dihydro-15-keto-PGJ2 5280881 PGD2 448457 13.14-dihydro-15-keto-PGD2 5283036 13.14-dihydro-15-keto-tetranor PGD2_PGE2 5283036 PGE1_PGD1_8-iso-PGE1_8-iso-PGA1 5280723 PGE2_PGD2_8-iso-PGA2 5280360 PGE2_13.14-dihydro-15-keto-PGE2 5280360 8-iso-PGE2 5283213 15-keto-PGE2 5280719 20-hydroxy-PGE2 5283034 Tetranor-PGEM_Tetranor-PGDM 161468 6-keto-PGF1a_1 5280888 6-keto-PGF1a_2 5280888 2.3-dinor-6-keto-PGF1a 53477747 6.15-diketo-13.14-dihydro-PGF1a 5283033 8-iso-PGF1a_8-iso-PGF1b 11222026 13.14-dihydro-15-keto-tetranor PGF1b_PGF1a 52195782 PGF2a 5280363 2.3-dinor-8-iso-PGF2a 9548881 13.14-dihydro-15-keto-PGF2a 91752945 11b-13.14-dihydro-15-keto-PGF2a_8-iso-13.14-dihydro-15-keto-PGF2a 25755792 20-hydroxy-PGF2a 53477777 Tetranor-PGFM 3082337 8-iso-15-keto-PGF2b 91885975 8-iso-PGF3a 5283217 15d-PGJ2 5311211 TXB2 5283137 11-dehydro-TXB2 5280891 iPF2a-IV 124489961 15-HpETE 6437084 5-oxo-ETE 5283159 12-oxo-ETE 5283162 5-HETE 5280733 8-HETE 11976122 11-HETE 14123410 12-HETE 13786989 15-HETE 9966861 20-HETE 5283157 5(S)-HETrE 5283143 12(S)-HETrE 10314080 15(S)-HETrE 5283145 5.15-DiHETE 5283158 5(6)-EET 5283202 8(9)-EET 6440706 11(12)-EET 40490664 14(15)-EET 5283205 12-HHT 5312765 PGE3_PGD3 5280937 PGF3a 5280940 5-HEPE 6439678 8-HEPE 5283186 12-HEPE 10041593 15-HEPE 5353282 18-HEPE 16061132 15-oxo-ETE 5280701 19(20)-EpDTE 88553637 MaR2 101894912 MCTR2 122368872 PD1 16042541 RvD2 11383310 RvD3 53477497 4-HDoHE 14429109 7-HDoHE 16061142 8-HDoHE 11976798 10-HDoHE 11537494 11-HDoHE 11631564 13-HDoHE 11559259 16-HDoHE_16(17)-EpDPE 11595378 17-HDoHE 6439179 20-HDoHE 16061143 19(20)-EpDPE 11631565 9.10-DiHOME 126456327 12.13-DiHOME 10236635 9-HODE 5282944 13-HODE 5282947 9-Oxo-ODE 9839084 13-Oxo-ODE 6446027 15-HEDE 13723965 13-HoTrE 10469728 PGD2_1 448457 PGD2_2 448457 PGE2-EA_PGD2-EA 5283119 15-keto-PGF2a_8-iso-15-keto-PGF2a 5280887 20-carboxy-AA 6437827 5(S)-HETrE_1 5283143 8(S)-HETrE_2 35025143 12(S)-HETrE_1 10314080 17.18-DiHETE 16061120 11.12-DiHETrE 16061184 LXA5_1 13914950 RvE2 16061125 MaR2_1 101894912 MCTR3 122368873 RvD1_1 44251266 13-HoTrE_1 10469728 13-HoTrE_2 10469728 18-carboxy-dinor-LTB4 6438938 12(S)-HETrE_2 10314080 LXA4_1 5280914 16-HETE 6442739 17-HETE 6442740 18-HETE 6442778 5.6-DiHETE 14429105 14.15-DiHETE 16061119 5.6-DiHETrE 40490673 8.9-DiHETrE 3246873 LTB5 5283125 LXA5_2 13914950 RvE3 72204623 14-HDoHE 11566378 METABOLITES_END #END