#METABOLOMICS WORKBENCH Fedorova_20240718_071832 DATATRACK_ID:5022 STUDY_ID:ST003364 ANALYSIS_ID:AN005510 PROJECT_ID:PR002090 VERSION 1 CREATED_ON August 1, 2024, 6:37 pm #PROJECT PR:PROJECT_TITLE Deep lipidomic profiling reveals sex dimorphism of lipid metabolism in PR:PROJECT_TITLE fibro-calcific aortic valve disease PR:PROJECT_SUMMARY In-depth lipidomics profiling was performed on human tricuspid and bicuspid PR:PROJECT_SUMMARY aortic valve tissue at different pathological stages, including mildly diseased, PR:PROJECT_SUMMARY fibrotic and calcific tissue sections. Untargeted and targeted analysis were PR:PROJECT_SUMMARY employed to enable high identification coverage and accurate quantification of PR:PROJECT_SUMMARY lipids. Chromatographic separation modes (C18 RPC, C30 RPC) was combined with MS PR:PROJECT_SUMMARY analysis using various acquisition modes (full MS, DDA, SRM) to allow for the PR:PROJECT_SUMMARY identification of 1084 lipid molecular species across 28 lipid subclasses, of PR:PROJECT_SUMMARY which 480 lipids were semi-absolutely quantified. PR:INSTITUTE Technical University Dresden PR:LAST_NAME Fedorova PR:FIRST_NAME Maria PR:ADDRESS Tatzberg 47/49, Dresden, Saxony, 01307, Germany PR:EMAIL maria.fedorova@tu-dresden.de PR:PHONE +49 351 796 36617 #STUDY ST:STUDY_TITLE Deep lipidomic profiling reveals sex dimorphism of lipid metabolism in ST:STUDY_TITLE fibro-calcific aortic valve disease ST:STUDY_SUMMARY In-depth lipidomics profiling was performed on human tricuspid and bicuspid ST:STUDY_SUMMARY aortic valve tissue at different pathological stages, including mildly diseased, ST:STUDY_SUMMARY fibrotic and calcific tissue sections. Untargeted and targeted analysis were ST:STUDY_SUMMARY employed to enable high identification coverage and accurate quantification of ST:STUDY_SUMMARY lipids. Chromatographic separation modes (C18 RPC, C30 RPC) was combined with MS ST:STUDY_SUMMARY analysis using various acquisition modes (full MS, DDA, SRM) to allow for the ST:STUDY_SUMMARY identification of 1084 lipid molecular species across 28 lipid subclasses, of ST:STUDY_SUMMARY which 480 lipids were semi-absolutely quantified. ST:INSTITUTE Technical University Dresden ST:LAST_NAME Fedorova ST:FIRST_NAME Maria ST:ADDRESS Tatzberg 47/49, Dresden, Saxony, 01307, Germany ST:EMAIL maria.fedorova@tu-dresden.de ST:PHONE +49 351 796 36617 #SUBJECT SU:SUBJECT_TYPE Human SU:SUBJECT_SPECIES Homo sapiens SU:TAXONOMY_ID 9606 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data SUBJECT_SAMPLE_FACTORS - F_pool_1.1 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_1.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_pos; Scan_range=250-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_pool_1.2 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_1.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_pos; Scan_range=250-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_pool_1.3 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_1.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_pos; Scan_range=250-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_pool_1.4 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_1.4.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=380-1200; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_pool_1.5 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_1.5.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=380-1200; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_pool_1.6 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_1.6.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=380-1200; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_pool_1.7 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_1.7.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=400-1600; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_pool_1.8 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_1.8.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=400-1600; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_pool_1.9 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_1.9.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=400-1600; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_pool_2.1 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_2.1.mzML; LC_method=C30, 57 min; MS_method=Exploris_DDA_pos; Scan_range=200-1200; Injection_Volume=2.5 SUBJECT_SAMPLE_FACTORS - F_pool_2.2 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_2.2.mzML; LC_method=C30, 57 min; MS_method=Exploris_DDA_pos; Scan_range=200-1200; Injection_Volume=2.5 SUBJECT_SAMPLE_FACTORS - F_pool_2.3 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_2.3.mzML; LC_method=C30, 57 min; MS_method=Exploris_DDA_pos; Scan_range=200-1200; Injection_Volume=2.5 SUBJECT_SAMPLE_FACTORS - F_pool_2.4 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_2.4.mzML; LC_method=C30, 57 min; MS_method=Exploris_DDA_neg; Scan_range=370-1480; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_pool_2.5 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_2.5.mzML; LC_method=C30, 57 min; MS_method=Exploris_DDA_neg; Scan_range=200-1400; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_pool_2.6 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids identification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_pool_2.6.mzML; LC_method=C30, 57 min; MS_method=Exploris_DDA_neg; Scan_range=370-1480; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_0.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS1 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_0.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_0.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS2 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_0.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_0.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS3 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_0.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_1.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS4 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_1.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_1.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS5 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_1.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_1.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS6 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_1.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_2.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS7 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_2.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_2.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS8 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_2.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_2.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS9 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_2.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_3.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS10 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_3.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_3.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS11 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_3.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_3.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS12 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_3.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_4.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS13 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_4.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_4.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS14 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_4.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_4.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS15 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_4.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_5.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS16 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_5.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_5.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS17 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_5.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_5.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS18 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_5.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_6.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS19 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_6.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_6.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS20 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_6.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-p_6.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS21 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-p_6.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_pos; Scan_range=100-1500; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal-n_0.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS22 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_0.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_0.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS23 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_0.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_0.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS24 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_0.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_1.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS25 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_1.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_1.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS26 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_1.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_1.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS27 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_1.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_2.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS28 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_2.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_2.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS29 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_2.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_2.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS30 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_2.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_3.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS31 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_3.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_3.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS32 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_3.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_3.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS33 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_3.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_4.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS34 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_4.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_4.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS35 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_4.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_4.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS36 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_4.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_5.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS37 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_5.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_5.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS38 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_5.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_5.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS39 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_5.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_6.1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS40 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_6.1.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_6.2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS41 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_6.2.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal-n_6.3 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS42 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal-n_6.3.mzML; LC_method=C30, 34 min; MS_method=QEx_MS1_neg; Scan_range=100-1500; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - F_cal_tQC1 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS43 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal_tQC1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_pos; Scan_range=250-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_cal_tQC2 Sample source:Aortic valve tissue | Analysis method:Folch extraction and untargeted MS44 | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_cal_tQC2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=150-1800; Injection_Volume=10 SUBJECT_SAMPLE_FACTORS - A_cal_tQC1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal_tQC1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal_tQC2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal_tQC2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal_tQC3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal_tQC3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_0.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_0.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_0.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_0.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_0.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_0.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_1.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_1.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_1.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_1.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_1.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_1.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_2.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_2.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_2.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_2.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_2.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_2.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_3.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_3.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_3.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_3.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_3.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_3.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_4.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_4.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_4.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_4.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_4.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_4.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_5.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_5.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_5.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_5.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_5.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_5.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_6.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_6.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_6.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_6.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal1_6.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal1_6.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_0.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_0.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_0.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_0.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_0.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_0.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_1.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_1.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_1.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_1.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_1.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_1.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_2.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_2.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_2.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_2.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_2.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_2.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_3.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_3.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_3.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_3.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_3.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_3.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_4.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_4.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_4.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_4.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_4.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_4.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_5.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_5.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_5.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_5.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_5.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_5.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_6.1 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_6.1.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_6.2 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_6.2.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_cal2_6.3 Sample source:Aortic valve tissue | Analysis method:acidified MeOH/CHCl3 extraction and targeted SRM | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_cal2_6.3.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_PRE_pool_0.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_PRE_pool_0.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_PRE_pool_0.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_PRE_pool_0.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_PRE_pool_0.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_PRE_pool_0.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_PRE_pool_1.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_PRE_pool_1.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_PRE_pool_1.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_PRE_pool_1.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_PRE_pool_1.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_PRE_pool_1.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_PRE_pool_2.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_PRE_pool_2.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_PRE_pool_2.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_PRE_pool_2.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_PRE_pool_2.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_PRE_pool_2.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_PRE_pool_3.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_PRE_pool_3.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_PRE_pool_3.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_PRE_pool_3.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_PRE_pool_3.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_PRE_pool_3.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_PRE_pool_0.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_PRE_pool_0.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_PRE_pool_0.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_PRE_pool_0.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_PRE_pool_0.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_PRE_pool_0.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_PRE_pool_1.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_PRE_pool_1.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_PRE_pool_1.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_PRE_pool_1.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_PRE_pool_1.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_PRE_pool_1.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_PRE_pool_2.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_PRE_pool_2.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_PRE_pool_2.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_PRE_pool_2.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_PRE_pool_2.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_PRE_pool_2.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_PRE_pool_3.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_PRE_pool_3.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_PRE_pool_3.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_PRE_pool_3.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_PRE_pool_3.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_PRE_pool_3.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_POST_pool_1.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_POST_pool_1.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_POST_pool_1.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_POST_pool_1.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_POST_pool_1.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_POST_pool_1.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_POST_pool_2.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_POST_pool_2.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_POST_pool_2.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_POST_pool_2.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_POST_pool_2.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_POST_pool_2.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_POST_pool_3.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_POST_pool_3.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_POST_pool_3.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_POST_pool_3.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - A_POST_pool_3.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_POST_pool_3.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_POST_pool_1.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_POST_pool_1.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_POST_pool_1.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_POST_pool_1.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_POST_pool_1.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_POST_pool_1.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_POST_pool_2.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_POST_pool_2.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_POST_pool_2.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_POST_pool_2.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_POST_pool_2.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_POST_pool_2.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_POST_pool_3.1 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_POST_pool_3.1.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_POST_pool_3.2 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_POST_pool_3.2.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_POST_pool_3.3 Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_POST_pool_3.3.mzML; LC_method=C30, 34 min; MS_method=QEx_DDA_neg; Scan_range=200-1200; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_01 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_01.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_BQC1 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_BQC1.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_BQC2 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_BQC2.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_BQC3 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_BQC3.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_BQC4 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_BQC4.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_BQC5 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_BQC5.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_BQC6 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_BQC6.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_1.1 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_1.1.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_1.2 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_1.2.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_1.3 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_1.3.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_1.4 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_1.4.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_1.5 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_1.5.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_1.6 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_1.6.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_1.7 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_1.7.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_02 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_02.mzML; LC_method=C30, 47 min; MS_method=Exploris_DDA_pos; Scan_range=200-1200; Injection_Volume=2.5 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_03 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_03.mzML; LC_method=C30, 47 min; MS_method=Exploris_DDA_neg; Scan_range=200-1400; Injection_Volume=5 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_04 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_04.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M03 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M03.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F08 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F08.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F28 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F28.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C35 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C35.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C27 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C27.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F19 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F19.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M08 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M08.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_05 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_05.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C17 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C17.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M20 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M20.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F18 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F18.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C28 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C28.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F26 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F26.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C13 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C13.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_06 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_06.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C08 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C08.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F11 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F11.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F24 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F24.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F29 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F29.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F34 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F34.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M14 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M14.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F13 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F13.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F37 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F37.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C07 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C07.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_07 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_07.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F35 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F35.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C16 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C16.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C05 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C05.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C12 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C12.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C02 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C02.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C15 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C15.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M09 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M09.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_08 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_08.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F32 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F32.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F25 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F25.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C18 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C18.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C19 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C19.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F20 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F20.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F31 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F31.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C33 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C33.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_09 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_09.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C21 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C21.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C34 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C34.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M13 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M13.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M01 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M01.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_10 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_10.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C09 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C09.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F05 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F05.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C25 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C25.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F16 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F16.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F15 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F15.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C23 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C23.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M06 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M06.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C30 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C30.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C01 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C01.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_11 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_11.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F06 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F06.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F17 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F17.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M17 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M17.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M18 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M18.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M21 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M21.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C29 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C29.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F21 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F21.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_12 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_12.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F12 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F12.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C26 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C26.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C24 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C24.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C20 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C20.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F36 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F36.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F14 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F14.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_13 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_13.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M15 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M15.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C11 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C11.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C31 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C31.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M05 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M05.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M19 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M19.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M10 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M10.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_14 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_14.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F03 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F03.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F23 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F23.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C03 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C03.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M16 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M16.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F04 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F04.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F30 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F30.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F09 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F09.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F27 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F27.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F07 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F07.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C14 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C14.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_15 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_15.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F10 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F10.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F01 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F01.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C10 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C10.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C22 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C22.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M04 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M04.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M02 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M02.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M11 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M11.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_16 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_16.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C06 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C06.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C04 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C04.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F33 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F33.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_C32 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_Ex_C32.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M07 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M07.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F02 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F02.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_17 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_17.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M22 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M22.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_F22 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_Ex_F22.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_M12 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_Ex_M12.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - F_Ex_tQC_18 Sample source:Aortic valve tissue | Analysis method:Untargeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_Ex_tQC_18.mzML; LC_method=C30, 47 min; MS_method=Exploris_MS1_pos; Scan_range=200-1200; Injection_Volume=2 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_01 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_01.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_02 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_02.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_03 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_03.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_04 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_04.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_05 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_05.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_BQC07 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_BQC07.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_BQC08 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_BQC08.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_BQC09 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_BQC09.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F49 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F49.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_C40 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=A_TSQ_C40.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F38 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F38.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_C36 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=A_TSQ_C36.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F39 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F39.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_M32 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=A_TSQ_M32.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F46 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F46.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_M27 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=A_TSQ_M27.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_C45 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=A_TSQ_C45.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_M36 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:BAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=A_TSQ_M36.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_M34 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=A_TSQ_M34.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_06 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_06.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F50 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F50.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F43 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F43.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_M35 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:BAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=A_TSQ_M35.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_M30 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=A_TSQ_M30.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F47 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F47.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F48 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F48.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F51 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F51.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_C47 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=A_TSQ_C47.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_C37 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=A_TSQ_C37.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_M33 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=A_TSQ_M33.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_C41 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=A_TSQ_C41.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_M29 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=A_TSQ_M29.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_C46 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=A_TSQ_C46.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F41 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F41.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F42 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F42.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_07 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_07.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_M31 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=A_TSQ_M31.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_M37 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:BAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=A_TSQ_M37.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F45 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F45.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_C44 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=A_TSQ_C44.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_M26 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=A_TSQ_M26.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_M28 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=A_TSQ_M28.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_C43 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=A_TSQ_C43.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F40 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F40.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_C38 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=A_TSQ_C38.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_C42 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=A_TSQ_C42.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_F44 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=A_TSQ_F44.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_C39 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=A_TSQ_C39.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_C48 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=A_TSQ_C48.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_BQC01 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_TSQ_BQC01.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_BQC02 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_TSQ_BQC02.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_08 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_08.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_BQC03 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_TSQ_BQC03.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_BQC04 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_TSQ_BQC04.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_BQC05 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_TSQ_BQC05.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_BQC06 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=F_TSQ_BQC06.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M03 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M03.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F08 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F08.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F28 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F28.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C35 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C35.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C27 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C27.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C10 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C10.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M08 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M08.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_09 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_09.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C17 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C17.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M20 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M20.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F19 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F19.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C28 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C28.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F26 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F26.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C13 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C13.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C08 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C08.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F12 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F12.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F24 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F24.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F29 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F29.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F34 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F34.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_10 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_10.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F11 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F11.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F14 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F14.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F37 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F37.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C07 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C07.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F35 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F35.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C16 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C16.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C05 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C05.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M12 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M12.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C12 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C12.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C02 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C02.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C15 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C15.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M09 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M09.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_11 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_11.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F32 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F32.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F25 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F25.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C18 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C18.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C19 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C19.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F20 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F20.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F31 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F31.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C33 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C33.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C21 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C21.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C34 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C34.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_12 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_12.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M01 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M01.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C09 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C09.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F05 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F05.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C25 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C25.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F16 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F16.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C23 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C23.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M06 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M06.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C30 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C30.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C01 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C01.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_13 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_13.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F06 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F06.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F18 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F18.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M17 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M17.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M18 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M18.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M21 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M21.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C29 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C29.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F21 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F21.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F13 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F13.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F17 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F17.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C26 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C26.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C24 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C24.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_14 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_14.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M11 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M11.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C20 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C20.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F36 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F36.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F15 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F15.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M15 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M15.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C11 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C11.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C31 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C31.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M05 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M05.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M19 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M19.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M10 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M10.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_15 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_15.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F03 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F03.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F23 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F23.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C03 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C03.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M16 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M16.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F04 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F04.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F30 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F30.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F09 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F09.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F27 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F27.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F07 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F07.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C14 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C14.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F10 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F10.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F01 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F01.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_16 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_16.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C22 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C22.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M04 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M04.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M02 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M02.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C06 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C06.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C04 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C04.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F33 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F33.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_C32 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:calcific RAW_FILE_NAME(Raw_file_names)=F_TSQ_C32.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M07 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M07.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F02 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F02.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M14 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M14.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_17 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_17.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M22 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M22.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_F22 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:BAV | Sex:male | Pathology:fibrotic RAW_FILE_NAME(Raw_file_names)=F_TSQ_F22.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - F_TSQ_M13 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:Folch | Morphology:TAV | Sex:female | Pathology:mildly diseased RAW_FILE_NAME(Raw_file_names)=F_TSQ_M13.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 SUBJECT_SAMPLE_FACTORS - A_TSQ_tQC_18 Sample source:Aortic valve tissue | Analysis method:Targeted lipidomics for human AV lipids quantification | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed RAW_FILE_NAME(Raw_file_names)=A_TSQ_tQC_18.mzML; LC_method=C18, 15 min; MS_method=TSQ_SRM_neg; Scan_range=SRM; Injection_Volume=3 #COLLECTION CO:COLLECTION_SUMMARY CAVD tissues were obtained from 55 patients undergoing aortic valve replacement CO:COLLECTION_SUMMARY for severe aortic stenosis. For all human tissue samples used in this study, CO:COLLECTION_SUMMARY tissue collection was approved by the local Ethical Committee (Medical Faculty, CO:COLLECTION_SUMMARY University Leipzig, registration number 128/19-ek) and all patients gave written CO:COLLECTION_SUMMARY informed consent in accordance with the Declaration of Helsinki. All samples CO:COLLECTION_SUMMARY showed macroscopic calcification as a sign of progressed FCAVD. Tissue samples CO:COLLECTION_SUMMARY were dissected into mildly diseased, fibrotic and calcific pieces on-site and CO:COLLECTION_SUMMARY flash frozen in liquid nitrogen. The deep frozen tissue sections were crushed CO:COLLECTION_SUMMARY into a thin powder in a percussion mortar in liquid nitrogen and stored at CO:COLLECTION_SUMMARY -80°C until further analysis. CO:SAMPLE_TYPE Aortic valve tissue CO:COLLECTION_LOCATION Leipzig, Germany CO:STORAGE_CONDITIONS -80? CO:STORAGE_VIALS Plastic tubes CO:ADDITIVES none #TREATMENT TR:TREATMENT_SUMMARY NA #SAMPLEPREP SP:SAMPLEPREP_SUMMARY Aortic valve tissue was spiked with tailored mixtures of internal standards and SP:SAMPLEPREP_SUMMARY lipids were extracted either using the Folch method or by acidified MeOH/CHCl3 SP:SAMPLEPREP_SUMMARY lipid extraction. SP:PROCESSING_STORAGE_CONDITIONS 4? SP:EXTRACTION_METHOD Folch lipid extraction or acidified MeOH/CHCl3 lipid extraction SP:EXTRACT_STORAGE -80? SP:SAMPLE_DERIVATIZATION none SP:SAMPLE_SPIKING aortic valve tissue specific internal standard mix #CHROMATOGRAPHY CH:CHROMATOGRAPHY_SUMMARY Four liquid chromatography methods were employed to allow optimal lipidome CH:CHROMATOGRAPHY_SUMMARY separation to enhance coverage of lipid species identifications and fast CH:CHROMATOGRAPHY_SUMMARY quantification. All details on the respective methods are provided in the CH:CHROMATOGRAPHY_SUMMARY attached methods document CH:CHROMATOGRAPHY_TYPE Reversed phase CH:INSTRUMENT_NAME Thermo Vanquish CH:COLUMN_NAME Thermo Accucore C30 (150 x 2.1mm,2.6um) CH:SOLVENT_A 50% acetonitrile/50% water; 5 mM ammonium formate; 0.1% formic acid CH:SOLVENT_B 85% isopropanol/10% acetonitrile/5% water; 5 mM ammonium formate; 0.1% formic CH:SOLVENT_B acid CH:FLOW_GRADIENT 0-20 min – 10 to 86% B, 20-22 min – 86 to 95% B, 22-26 min – 95% B, CH:FLOW_GRADIENT 26-26.1 min – 95 to 10% B, followed by 7.9 min re-equilibration at 10% B. CH:FLOW_RATE 0.3 mL/min CH:COLUMN_TEMPERATURE 50 °C CH:METHODS_FILENAME FCAVD_methods.pdf #ANALYSIS AN:ANALYSIS_TYPE MS #MS MS:INSTRUMENT_NAME Thermo Exploris 240 Orbitrap MS:INSTRUMENT_TYPE Orbitrap MS:MS_TYPE ESI MS:ION_MODE NEGATIVE MS:MS_COMMENTS DDA with with inclusion list for the assessment of PA and LPA recovery rates of MS:MS_COMMENTS Folch and acidified MeOH/CHCl3 lipid extraction in negative ion mode #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS Peak area MS_METABOLITE_DATA_START Samples A_PRE_pool_0.1 A_PRE_pool_0.2 A_PRE_pool_0.3 A_PRE_pool_1.1 A_PRE_pool_1.2 A_PRE_pool_1.3 A_PRE_pool_2.1 A_PRE_pool_2.2 A_PRE_pool_2.3 A_PRE_pool_3.1 A_PRE_pool_3.2 A_PRE_pool_3.3 F_PRE_pool_0.1 F_PRE_pool_0.2 F_PRE_pool_0.3 F_PRE_pool_1.1 F_PRE_pool_1.2 F_PRE_pool_1.3 F_PRE_pool_2.1 F_PRE_pool_2.2 F_PRE_pool_2.3 F_PRE_pool_3.1 F_PRE_pool_3.2 F_PRE_pool_3.3 A_POST_pool_1.1 A_POST_pool_1.2 A_POST_pool_1.3 A_POST_pool_2.1 A_POST_pool_2.2 A_POST_pool_2.3 A_POST_pool_3.1 A_POST_pool_3.2 A_POST_pool_3.3 F_POST_pool_1.1 F_POST_pool_1.2 F_POST_pool_1.3 F_POST_pool_2.1 F_POST_pool_2.2 F_POST_pool_2.3 F_POST_pool_3.1 F_POST_pool_3.2 F_POST_pool_3.3 Factors Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:acidified MeOH/CHCl3 | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed Sample source:Aortic valve tissue | Analysis method:Assessment of PA and LPA recovery rates | Extraction method:Folch | Morphology:mixed | Sex:mixed | Pathology:mixed LPA 18:1 5332581 6728415 6169662 10602407 7858667 8554394 34908976 29351025 24920684 213152586 198726677 225066408 33331 24147 29381 329487 416904 295711 2939122 3487477 4165352 49734662 40558575 39486049 11677171 8749481 9579299 42070071 38098065 34586919 344148432 358988274 379400893 3065377 3269661 3144931 32580459 31418831 34040438 295880063 291045821 259858095 PA 17:0_17:0 836019 686461 505664 1515346 1706988 1404531 15824779 15260202 15224684 137672714 124459064 152097932 1269311 946591 780709 1378430 1471309 1294683 8387086 8940444 9271386 85542552 92009514 89424219 1019469 756897 853616 9515416 9721016 8219428 75153155 72475496 89912800 3336899 2913708 2582018 15434136 16434298 17639063 103843968 92891520 92395037 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name m/z RT_min LPA 18:1 435.2517 7.9 PA 17:0_17:0 675.497 19.9 METABOLITES_END #END