#METABOLOMICS WORKBENCH SatoH_20240725_081106 DATATRACK_ID:5032 STUDY_ID:ST003393 ANALYSIS_ID:AN005567 PROJECT_ID:PR002102 VERSION 1 CREATED_ON August 8, 2024, 10:13 am #PROJECT PR:PROJECT_TITLE Group X Phospholipase A2 Links Colonic Lipid Homeostasis to Systemic Metabolism PR:PROJECT_TITLE via Host-Microbiota Interaction PR:PROJECT_SUMMARY The gut microbiota influences physiological functions of the host, ranging from PR:PROJECT_SUMMARY the maintenance of local gut homeostasis to systemic immunity and metabolism. PR:PROJECT_SUMMARY Secreted phospholipase A2 group X (sPLA2-X) is abundantly expressed in colonic PR:PROJECT_SUMMARY epithelial cells but is barely detectable in metabolic and immune tissues. PR:PROJECT_SUMMARY Despite this distribution, sPLA2-X-deficient (Pla2g10-/-) mice displayed PR:PROJECT_SUMMARY variable obesity-related phenotypes that were abrogated after treatment with PR:PROJECT_SUMMARY antibiotics or cohousing with Pla2g10+/+ mice, suggesting the involvement of gut PR:PROJECT_SUMMARY microbiota. Under housing conditions where Pla2g10-/- mice showed aggravation of PR:PROJECT_SUMMARY diet-induced obesity and insulin resistance, they displayed increased colonic PR:PROJECT_SUMMARY inflammation and epithelial damage, reduced production of polyunsaturated fatty PR:PROJECT_SUMMARY acids (PUFAs) and lysophospholipids, decreased abundance of several Clostridium PR:PROJECT_SUMMARY species, and reduced levels of short-chain fatty acids (SCFAs). These PR:PROJECT_SUMMARY obesity-related phenotypes in Pla2g10-/- mice were reversed by dietary PR:PROJECT_SUMMARY supplementation with omega-3 PUFAs or SCFAs. Thus, colonic sPLA2-X orchestrates PR:PROJECT_SUMMARY omega-3 PUFA-SCFA interplay via modulation of gut microbiota, thereby PR:PROJECT_SUMMARY secondarily affecting systemic metabolism. PR:INSTITUTE University of Tokyo PR:LAST_NAME Sato PR:FIRST_NAME Hiroyasu PR:ADDRESS Tokyo 113-8655, Japan. PR:EMAIL sato-hr@m.u-tokyoac.jp PR:PHONE 81-3-5841-1433 #STUDY ST:STUDY_TITLE Free fatty acid and lysophospholipids analysis of colon in Pla2g10 knockout ST:STUDY_TITLE mice. ST:STUDY_SUMMARY We performed lipidomic analysis on the colons of WT and Pla2g10 knockout mice. ST:INSTITUTE University of Tokyo ST:LAST_NAME Sato ST:FIRST_NAME Hiroyasu ST:ADDRESS 7-3-1 Hongo, Bunkyo-ku Tokyo 113-8655, Japan. ST:EMAIL sato-hr@m.u-tokyo.ac.jp ST:PHONE 81-3-5841-1433 #SUBJECT SU:SUBJECT_TYPE Mammal SU:SUBJECT_SPECIES Mus musculus SU:TAXONOMY_ID 10090 SU:GENDER Female #FACTORS #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data SUBJECT_SAMPLE_FACTORS L_WT_1 L_1 Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_WT_1.mzML SUBJECT_SAMPLE_FACTORS L_WT_2 L_2 Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_WT_2.mzML SUBJECT_SAMPLE_FACTORS L_WT_3 L_3 Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_WT_3.mzML SUBJECT_SAMPLE_FACTORS L_WT_15 L_15 Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_WT_15.mzML SUBJECT_SAMPLE_FACTORS L_WT_16 L_16 Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_WT_16.mzML SUBJECT_SAMPLE_FACTORS L_WT_17 L_17 Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_WT_17.mzML SUBJECT_SAMPLE_FACTORS L_WT_18 L_18 Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_WT_18.mzML SUBJECT_SAMPLE_FACTORS L_WT_19 L_19 Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_WT_19.mzML SUBJECT_SAMPLE_FACTORS L_KO_4 L_4 Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_KO_4.mzML SUBJECT_SAMPLE_FACTORS L_KO_5 L_5 Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_KO_5.mzML SUBJECT_SAMPLE_FACTORS L_KO_6 L_6 Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_KO_6.mzML SUBJECT_SAMPLE_FACTORS L_KO_25 L_25 Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_KO_25.mzML SUBJECT_SAMPLE_FACTORS L_KO_26 L_26 Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_KO_26.mzML SUBJECT_SAMPLE_FACTORS L_KO_27 L_27 Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_KO_27.mzML SUBJECT_SAMPLE_FACTORS L_KO_28 L_28 Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Raw file name=L_KO_28.mzML SUBJECT_SAMPLE_FACTORS H_WT_7 H_7 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_WT_7.mzML SUBJECT_SAMPLE_FACTORS H_WT_8 H_8 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_WT_8.mzML SUBJECT_SAMPLE_FACTORS H_WT_9 H_9 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_WT_9.mzML SUBJECT_SAMPLE_FACTORS H_WT_10 H_10 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_WT_10.mzML SUBJECT_SAMPLE_FACTORS H_WT_20 H_20 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_WT_20.mzML SUBJECT_SAMPLE_FACTORS H_WT_21 H_21 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_WT_21.mzML SUBJECT_SAMPLE_FACTORS H_WT_22 H_22 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_WT_22.mzML SUBJECT_SAMPLE_FACTORS H_WT_23 H_23 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_WT_23.mzML SUBJECT_SAMPLE_FACTORS H_KO_11 H_11 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_KO_11.mzML SUBJECT_SAMPLE_FACTORS H_KO_12 H_12 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_KO_12.mzML SUBJECT_SAMPLE_FACTORS H_KO_13 H_13 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_KO_13.mzML SUBJECT_SAMPLE_FACTORS H_KO_14 H_14 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_KO_14.mzML SUBJECT_SAMPLE_FACTORS H_KO_29 H_29 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_KO_29.mzML SUBJECT_SAMPLE_FACTORS H_KO_30 H_30 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_KO_30.mzML SUBJECT_SAMPLE_FACTORS H_KO_31 H_31 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_KO_31.mzML SUBJECT_SAMPLE_FACTORS H_KO_32 H_32 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=H_KO_32.mzML SUBJECT_SAMPLE_FACTORS LCo_WT_114 LW_114 Genotype:Pla2g10+/+ | Treatment:Low fat diet | :co-housed | Sample source:Colon Raw file name=LCo_WT_114.mzML SUBJECT_SAMPLE_FACTORS LCo_WT_119 LW_119 Genotype:Pla2g10+/+ | Treatment:Low fat diet | :co-housed | Sample source:Colon Raw file name=LCo_WT_119.mzML SUBJECT_SAMPLE_FACTORS LCo_WT_138 LW_138 Genotype:Pla2g10+/+ | Treatment:Low fat diet | :co-housed | Sample source:Colon Raw file name=LCo_WT_138.mzML SUBJECT_SAMPLE_FACTORS LCo_WT_140 LW_140 Genotype:Pla2g10+/+ | Treatment:Low fat diet | :co-housed | Sample source:Colon Raw file name=LCo_WT_140.mzML SUBJECT_SAMPLE_FACTORS LCo_WT_141 LW_ 141 Genotype:Pla2g10+/+ | Treatment:Low fat diet | :co-housed | Sample source:Colon Raw file name=LCo_WT_141.mzML SUBJECT_SAMPLE_FACTORS LCo_KO_112 LK_ 112 Genotype:Pla2g10-/- | Treatment:Low fat diet | :co-housed | Sample source:Colon Raw file name=LCo_KO_112.mzML SUBJECT_SAMPLE_FACTORS LCo_KO_114 LK_114 Genotype:Pla2g10-/- | Treatment:Low fat diet | :co-housed | Sample source:Colon Raw file name=LCo_KO_114.mzML SUBJECT_SAMPLE_FACTORS LCo_KO_122 LK_122 Genotype:Pla2g10-/- | Treatment:Low fat diet | :co-housed | Sample source:Colon Raw file name=LCo_KO_122.mzML SUBJECT_SAMPLE_FACTORS LCo_KO_143 LK_ 143 Genotype:Pla2g10-/- | Treatment:Low fat diet | :co-housed | Sample source:Colon Raw file name=LCo_KO_143.mzML SUBJECT_SAMPLE_FACTORS LCo_KO_146 LK_146 Genotype:Pla2g10-/- | Treatment:Low fat diet | :co-housed | Sample source:Colon Raw file name=LCo_KO_146.mzML SUBJECT_SAMPLE_FACTORS HCo_WT_18 HW_ 18 Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_WT_18.mzML SUBJECT_SAMPLE_FACTORS HCo_WT_22 HW_ 22 Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_WT_22.mzML SUBJECT_SAMPLE_FACTORS HCo_WT_23 HW_ 23 Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_WT_23.mzML SUBJECT_SAMPLE_FACTORS HCo_WT_127 HW_127 Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_WT_127.mzML SUBJECT_SAMPLE_FACTORS HCo_WT_128 HW_128 Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_WT_128.mzML SUBJECT_SAMPLE_FACTORS HCo_WT_131 HW_131 Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_WT_131.mzML SUBJECT_SAMPLE_FACTORS HCo_WT_139 HW_139 Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_WT_139.mzML SUBJECT_SAMPLE_FACTORS HCo_KO_20 HK_ 20 Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_KO_20.mzML SUBJECT_SAMPLE_FACTORS HCo_KO_22 HK_ 22 Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_KO_22.mzML SUBJECT_SAMPLE_FACTORS HCo_KO_23 HK_ 23 Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_KO_23.mzML SUBJECT_SAMPLE_FACTORS HCo_KO_132 HK_ 132 Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_KO_132.mzML SUBJECT_SAMPLE_FACTORS HCo_KO_133 HK_ 133 Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_KO_133.mzML SUBJECT_SAMPLE_FACTORS HCo_KO_134 HK_ 134 Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_KO_134.mzML SUBJECT_SAMPLE_FACTORS HCo_KO_138 HK_ 138 Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Raw file name=HCo_KO_138.mzML SUBJECT_SAMPLE_FACTORS HC_WT_1 HCt_1 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_WT_1.mzML SUBJECT_SAMPLE_FACTORS HC_WT_2 HCt_2 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_WT_2.mzML SUBJECT_SAMPLE_FACTORS HC_WT_3 HCt_3 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_WT_3.mzML SUBJECT_SAMPLE_FACTORS HS_WT_4 HS_4 Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_WT_4.mzML SUBJECT_SAMPLE_FACTORS HS_WT_5 HS_5 Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_WT_5.mzML SUBJECT_SAMPLE_FACTORS HS_WT_6 HS_6 Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_WT_6.mzML SUBJECT_SAMPLE_FACTORS HC_KO_7 HCt_7 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_KO_7.mzML SUBJECT_SAMPLE_FACTORS HC_KO_9 HCt_9 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_KO_9.mzML SUBJECT_SAMPLE_FACTORS HS_KO_10 HS_10 Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_KO_10.mzML SUBJECT_SAMPLE_FACTORS HS_KO_11 HS_11 Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_KO_11.mzML SUBJECT_SAMPLE_FACTORS HS_KO_12 HS_12 Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_KO_12.mzML SUBJECT_SAMPLE_FACTORS HC_WT_13 HCt_13 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_WT_13.mzML SUBJECT_SAMPLE_FACTORS HC_WT_14 HCt_14 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_WT_14.mzML SUBJECT_SAMPLE_FACTORS HC_WT_15 HCt_15 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_WT_15.mzML SUBJECT_SAMPLE_FACTORS HC_WT_16 HCt_16 Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_WT_16.mzML SUBJECT_SAMPLE_FACTORS HS_WT_17 HS_17 Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_WT_17.mzML SUBJECT_SAMPLE_FACTORS HS_WT_18 HS_18 Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_WT_18.mzML SUBJECT_SAMPLE_FACTORS HS_WT_19 HS_19 Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_WT_19.mzML SUBJECT_SAMPLE_FACTORS HS_WT_20 HS_20 Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_WT_20.mzML SUBJECT_SAMPLE_FACTORS HC_KO_21 HCt_21 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_KO_21.mzML SUBJECT_SAMPLE_FACTORS HC_KO_22 HCt_22 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_KO_22.mzML SUBJECT_SAMPLE_FACTORS HC_KO_23 HCt_23 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_KO_23.mzML SUBJECT_SAMPLE_FACTORS HC_KO_24 HCt_24 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_KO_24.mzML SUBJECT_SAMPLE_FACTORS HC_KO_25 HCt_25 Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Raw file name=HC_KO_25.mzML SUBJECT_SAMPLE_FACTORS HS_KO_26 HS_26 Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_KO_26.mzML SUBJECT_SAMPLE_FACTORS HS_KO_27 HS_27 Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_KO_27.mzML SUBJECT_SAMPLE_FACTORS HS_KO_28 HS_28 Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_KO_28.mzML SUBJECT_SAMPLE_FACTORS HS_KO_29 HS_29 Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Raw file name=HS_KO_29.mzML #COLLECTION CO:COLLECTION_SUMMARY All mice groups underwent anesthesia with isoflurane. The mouse colons were CO:COLLECTION_SUMMARY excised and rinsed in ice-cold PBS. Colon was collected and was quickly frozen CO:COLLECTION_SUMMARY by using liquid nitrogen. Samples were preserved below -80 °C and were sent out CO:COLLECTION_SUMMARY for lipidomic analysis. CO:SAMPLE_TYPE Colon #TREATMENT TR:TREATMENT_SUMMARY Pla2g10+/+ and Pla2g10-/- mice were subjected to high-fat diet (HFD) or low-fat TR:TREATMENT_SUMMARY diet (LFD) for 24 weeks. Additionally, co-housed mice were given same diets. TR:TREATMENT_SUMMARY Furthermore, for mice on HFD, the effects of adding short-chain fatty acids TR:TREATMENT_SUMMARY (SCFAs) to drinking water were compared with those without SCFAs. #SAMPLEPREP SP:SAMPLEPREP_SUMMARY Tissues were soaked in methanol and homogenized with bead homogenizer (Bertin SP:SAMPLEPREP_SUMMARY Instruments). Lipids were extracted from the homogenates by the method of Bligh SP:SAMPLEPREP_SUMMARY and Dyer #CHROMATOGRAPHY CH:CHROMATOGRAPHY_TYPE Reversed phase CH:INSTRUMENT_NAME Shimadzu Nexera X2 CH:COLUMN_NAME Phenomenex Kinetex C18 (50 x 2.1mm,1.7um) CH:SOLVENT_A 33.3% acetonitrile/33.3% methanol/33.3% water; 5 μM phosphoric acid; 1 mM CH:SOLVENT_A ammonium formate CH:SOLVENT_B 100% isopropanol; 5 μM phosphoric acid; 1 mM ammonium formate CH:FLOW_GRADIENT 0–3 min 0% B; 3–6 min 0–60% B; 6–17 min 60–62.2% B; 17–17.01 min CH:FLOW_GRADIENT 62.2–69.8% B; 17.01–20 min 69.8–100% B; 20–23 min 100% B; 23–23.10 min CH:FLOW_GRADIENT 100–0% B; 23.10–26 min 0% B CH:FLOW_RATE 0.2 ml/min CH:COLUMN_TEMPERATURE 50 #ANALYSIS AN:ANALYSIS_TYPE MS #MS MS:INSTRUMENT_NAME ABI Sciex 4000 QTrap MS:INSTRUMENT_TYPE Triple quadrupole MS:MS_TYPE ESI MS:ION_MODE NEGATIVE MS:MS_COMMENTS - #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS Peak area/mg of wet tissue MS_METABOLITE_DATA_START Samples L_1 L_2 L_3 L_15 L_16 L_17 L_18 L_19 L_4 L_5 L_6 L_25 L_26 L_27 L_28 H_7 H_8 H_9 H_10 H_20 H_21 H_22 H_23 H_11 H_12 H_13 H_14 H_29 H_30 H_31 H_32 LW_114 LW_119 LW_138 LW_140 LW_ 141 LK_ 112 LK_114 LK_122 LK_ 143 LK_146 HW_ 18 HW_ 22 HW_ 23 HW_127 HW_128 HW_131 HW_139 HK_ 20 HK_ 22 HK_ 23 HK_ 132 HK_ 133 HK_ 134 HK_ 138 HCt_1 HCt_2 HCt_3 HS_4 HS_5 HS_6 HCt_7 HCt_9 HS_10 HS_11 HS_12 HCt_13 HCt_14 HCt_15 HCt_16 HS_17 HS_18 HS_19 HS_20 HCt_21 HCt_22 HCt_23 HCt_24 HCt_25 HS_26 HS_27 HS_28 HS_29 Factors Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:Low fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:Low fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:Low fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:Low fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:Low fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:Low fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10-/- | Treatment:Low fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10-/- | Treatment:Low fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10-/- | Treatment:Low fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10-/- | Treatment:Low fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10-/- | Treatment:Low fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :co-housed | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Genotype:Pla2g10+/+ | Treatment:High fat diet+SCFA | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Genotype:Pla2g10-/- | Treatment:High fat diet+SCFA | :- | Sample source:Colon Palmitic acid 1908253.78 2314962.435 1290823.903 561831.9184 1120792.079 1796138.395 2165176.487 1736436.274 1260073.049 1387396.488 838395.9437 1508362.722 4992773.22 1114113.08 1185605.201 1342623.032 1230355.402 996709.6894 1301047.273 3802608.916 1445242.865 1695167.884 1370866.05 1065357.778 2695709.005 1067756.078 1353577.07 872974.5357 1206456.933 1057407.884 2809591.644 2913324.433 1530047.142 2034778.292 1483385.034 1579374.181 3441601.81 2811267.337 2102990.044 1951013.094 2270498.269 2750022.511 5884611.762 4226777.55 3493859.187 3228365.41 7221970.306 2886564.763 3032081.457 3755844.513 2796379.555 4226996.66 3725423.002 10069387.39 5004554.192 9777501.806 5071420.952 4461676.811 3439763.322 2475316.049 4413986.428 2521401.538 6882578.259 3489626.528 4633460.623 3329128.53 5120333.422 2533604.475 3652430.461 2653292.472 4977305.533 8440728.615 4088067.308 6057984.414 3662792.05 5155024.366 2892352.054 3561670.703 6444457.678 4094637.047 5565175.321 5390549.545 5183388.054 Palmitoleic acid 1200987.654 1352053.649 625112.2232 258387.2515 714158.4158 1148520.156 1244381.651 1162627.961 661183.1699 706112.0129 515092.9327 815367.5956 2375839.648 493212.9251 525211.3793 735298.4805 567822.5214 582963.5963 682133.1426 2192092.199 725405.5048 768628.8253 891569.7223 556388.6318 1653029.107 546432.8418 763996.1833 474631.1403 755031.4649 685105.7687 1680145.153 2005846.153 882910.4146 1279135.277 825717.3081 909234.6031 2100470.934 1625173.36 1357778.924 1119203.245 1163275.705 1563947.228 3295948.415 2901142.276 2253754.846 1770812.3 6274533.607 1711182.623 1465815.822 1803338.516 1512774.038 2334912.006 2245587.586 3200363.787 1710434.773 9169901.201 3085081.3 2325150.766 2139049.711 1383518.928 2661628.246 1825913.702 4789068.675 1930953.058 2494406.306 2183424.718 3095101.614 1763763.792 2076003.304 1815536.287 2927831.677 5934490.142 2007788.336 4013668.825 2457321.285 3093026.898 1746507.485 2166468.05 4293141.181 2632059.015 3864576.651 3450258.39 3316077.56 Stearic acid 2861176.471 3067887.11 1425757.392 1594826.615 2765346.535 4256839.731 4295744.759 4165645.697 1198872.624 1526262.378 1035665.577 3385021.129 10150111.74 2125320.333 2276030.928 1780602.772 1989671.217 1279358.706 1816282.223 7169036.221 3467716.72 4285262.237 3764180.254 1579746.294 4134692.035 1805101.634 2444101.562 2190671.948 2799499.782 2267929.251 5151697.158 2326203.449 1433876.295 1844906.649 1590153.378 1725861.978 1796893.437 1843988.498 2050613.143 1430218.016 1977776.303 2423790.332 4444893.714 2822235.414 1957208.156 2087064.412 4153973.638 2340305.712 4509191.272 3762735.173 4517328.516 2250096.826 2579416.562 1987360.068 2400659.971 11475698.02 2833004.131 3584031.027 4277678.648 2894695.219 4313509.025 1673558.961 3125923.937 3295212.209 4526853.201 1818303.907 2867205.852 3148898.175 4430493.921 2165565.621 5014341.305 6346800.869 6900651.206 4278863.404 2165467.19 2427949.329 3121094.956 3651380.657 2284821.381 2016980.219 4686262.256 5141593.376 4865476.269 oleic acid 1285281.574 1605383.103 1023942.18 861554.7952 1083168.317 1624211.664 1444460.398 1386859.79 708722.7862 1071371.385 614372.4216 1102698.827 3010509.334 812430.9988 873340.6553 485197.707 629936.9416 375114.2949 547666.3034 3523005.319 978601.4134 1130570.076 997868.855 536517.6092 1436863.762 504184.9342 560587.918 529853.0648 652808.049 618722.3389 1560234.961 1572279.887 753855.3434 806377.9479 926799.7636 996369.5859 715349.0635 954236.8769 1097232.158 794128.1315 1249085.454 752137.3044 1399324.213 687673.2983 510419.7578 678894.5184 1224964.147 550683.8294 1128393.345 876201.4366 872469.272 556986.2743 655809.373 499946.7162 633210.7061 1481569.909 659742.6125 767395.2759 873688.3448 645196.1892 830910.1904 411119.6827 580669.6845 586433.5908 907958.3669 684273.5173 644980.3592 681451.6712 916697.5292 481864.3308 1019255.682 1109011.916 2324573.038 1078980.879 329553.332 406234.0504 574613.3606 637938.1715 365560.545 400026.3566 604286.874 853526.1976 718247.6857 Linoleic acid 99306.26527 105971.3386 89259.09969 70294.31909 86396.0396 112578.9459 102505.2085 97104.57875 66282.2467 117993.9263 61405.00856 75207.72951 153229.8615 64074.62782 61263.16581 29616.03557 37268.65216 26131.08752 32924.4616 260674.4333 70297.82557 69135.36046 70697.1586 61148.5558 77353.28513 32056.59625 30302.51329 23735.89155 32223.6643 41073.46269 94432.19837 176618.0356 77805.31693 63264.92385 81687.25933 90123.67061 65225.56724 82816.45788 100622.4273 74969.74499 112590.6944 57098.82806 142667.2569 52683.48122 47025.11607 53932.458 108620.0423 49823.00885 76292.53648 57297.1799 63351.27198 42377.65508 38620.72117 44959.03692 47039.32004 72179.08526 68568.75722 66110.84875 48795.23615 39310.27133 55599.5233 36104.0843 56818.26569 29862.101 54855.30081 36347.3714 60313.8826 49604.99956 59766.76447 45747.8879 64601.02124 77565.40892 123779.8044 109101.4786 29360.92129 29813.3049 30255.33302 37687.15397 29498.57775 28639.62775 40493.7931 50653.84981 40268.43144 AA 139044.8274 114110.631 64660.60532 41169.33254 29554.45545 36885.72291 24204.12077 35201.58256 105953.2369 72504.82707 50574.51886 26679.55489 95459.38426 30987.25446 27398.58443 135586.1714 121339.7977 110967.6319 107914.854 136474.5156 56145.45805 161270.0257 84304.46117 118413.2299 154918.4971 90514.14906 86349.86802 42157.64813 80418.20521 40271.92902 98405.83047 197573.7384 97908.12609 73288.91664 107779.1681 79515.93358 65495.06163 75788.28954 80145.65327 59390.88575 69339.81302 194099.9495 207155.9376 160443.9518 101724.501 99684.26198 313279.7763 78946.09815 215709.3687 146087.7596 169060.217 94793.43614 92823.26241 78502.11376 108261.3496 130960.2278 113188.9727 213757.7728 139966.5681 102290.4455 144478.2151 105182.3159 97776.76403 75696.17317 169131.2908 54757.18466 122645.535 129967.7044 110235.592 142210.6869 105635.1882 192362.6577 147026.0131 142421.0777 89979.09791 78477.7942 71238.67473 82024.5977 51590.70236 75563.42766 79833.5855 69402.34312 69152.12222 DPA 47036.00713 28832.68053 17917.49553 8211.694141 5592.079208 6627.031562 3168.814739 5698.67837 22387.33427 21389.55519 14833.90286 4073.471473 10455.07542 6470.46635 5227.974071 1304.56182 1649.894662 1541.552859 732.7083524 2324.624303 1402.863098 1517.709769 693.921752 1447.423348 1835.992585 998.8043045 476.9257611 713.98394 852.352079 391.8266531 799.4012832 61542.32266 22683.91058 22584.73223 34664.96457 32050.51976 17961.00807 18352.93857 35008.67821 16619.32456 19971.52698 2868.875943 2522.650074 2005.549397 789.7128225 454.8244099 2132.849832 834.2719228 3731.366733 992.3780525 2051.198104 655.5714478 989.262203 569.4996817 991.8441551 3535.409017 47.8802761 80.50023262 163.4674686 19.73046434 33.43250009 986.1627907 121.5445189 93.98063585 152.1620569 68.83342544 151.915722 138.6783847 158.8941003 96.7420933 95.20657799 68.32372446 121.4508052 148.3126754 101.826436 44.03628958 50.71723818 70.24709838 92.61090637 30.02216147 94.39463552 124.4700816 98.23314836 EPA 24429.1807 20773.65735 12030.57431 17310.28292 10564.35644 7346.148176 7226.628016 6154.647696 12447.72943 13028.14536 10778.91594 3275.609705 9580.462616 3233.133056 3707.171587 16768.9976 27370.5403 18400.07906 29782.47669 32881.38298 12706.19664 30681.01152 29254.43355 18990.37497 34247.37226 14101.23555 13146.91037 3501.434111 6827.151395 4659.171375 5703.330792 27928.89359 13985.10242 10938.75901 14145.22611 17292.29514 10922.44886 14512.80535 14458.51071 10803.967 15944.00491 29008.43418 30114.62643 17859.25299 17972.52668 19513.85273 55795.97727 29469.02655 14154.21556 12798.93502 18585.50962 18260.20928 21825.83244 18621.6473 24242.97821 64954.81651 59060.32345 79661.23345 46472.69227 31890.66204 48856.04961 18896.64486 18233.71894 17829.23973 23244.67534 10411.11567 57634.61675 51598.57422 64831.63156 58822.9739 51268.85113 61698.79916 90310.54858 50926.47585 18427.94968 17086.53095 17425.37386 15890.21834 12248.90589 14021.84925 18878.41011 21366.90456 17483.88644 DHA 249188.8823 180123.9842 108722.9569 168114.0469 79801.9802 93939.77387 65560.93839 65393.13177 114040.436 95564.981 103308.6889 33210.57527 84641.80485 31302.27229 33968.03733 28259.07063 49189.09399 32509.28572 47768.28568 63330.21467 43926.47407 89569.00577 77538.81911 25611.0384 38817.9271 20127.54085 23960.65874 9267.227196 17417.20311 10522.69847 21158.42227 258152.5805 122850.5004 107158.3279 128880.1307 164630.395 106291.7556 102451.856 150016.2228 91223.50065 135842.3682 43754.45653 43411.5857 42280.92664 17631.04868 20960.43179 62655.95525 23958.16573 46647.56179 25782.10535 37183.36841 15416.40619 18365.29546 17397.51511 21378.07087 89752.71101 107778.513 142237.5342 104780.1601 68712.94034 104421.7984 34865.67103 40051.39903 30636.13471 48620.81934 22678.85701 119525.3124 92584.93987 97312.91167 100072.2691 106559.9653 136401.8915 131344.3614 103627.7464 26745.36733 26380.91282 27213.8161 28800.23228 17064.65073 29212.3546 30774.50328 28874.56194 33151.78392 LPC160 3073565.521 2408930.693 2736801.398 1761204.53 2799348.015 3449622.691 3344017.153 3403217.257 3209338.381 3759544.554 4107573.675 3047202.908 3579381.581 2559008.123 2774977.498 2911705.3 3050442.632 3099652.883 2828107.164 2416438.356 3254986.862 2458196.999 2718485.996 2995896.331 3719820.617 3557367.501 3342146.768 1573358.058 2396796.929 2642398.031 2808708.817 2887856.772 3130822.981 3735703.403 3290458.456 2352643.307 1404609.883 3447462.135 3008534.397 2771601.466 3300295.999 2579043.297 4158975.165 5087713.69 2768883.736 2887046.022 9085088.462 3094127.112 2663858.467 2918116.684 2151878.497 3082342.177 2805510.535 6221453.287 5797432.24 4510000 10300000 9050000 6370000 4020000 8720000 6230000 12800000 6610000 8630000 8110000 11700000 5560000 8780000 7790000 10300000 14300000 6080000 10300000 7710000 9550000 7500000 8810000 8120000 7890000 8060000 7660000 8970000 LPC161 131266.8608 116148.0489 148875.8299 71811.77662 114704.5057 93594.41409 80825.53087 94765.35808 146267.0938 183026.5579 259628.5381 61758.65697 93136.465 70741.2659 64763.07778 147156.4356 151069.5399 168500.6407 137373.675 51561.64384 85104.64754 62961.1258 93590.36643 163638.9051 182137.2161 198145.3698 174963.1916 32015.91958 49722.78212 69840.87402 40896.93878 182244.5379 188639.4919 183426.0426 198739.9409 110558.3945 65339.41144 142653.6056 151835.8695 165599.9818 153875.7833 119273.2688 141435.4829 253507.6668 152886.3632 119449.6614 366323.9722 157361.2228 119292.3336 107676.5609 85691.44684 108325.7091 109805.5105 246885.8131 280456.4907 346000 434000 406000 223000 172000 400000 292000 386000 263000 251000 312000 480000 407000 484000 409000 454000 538000 343000 373000 282000 313000 339000 398000 234000 248000 220000 287000 296000 LPC180 980647.6412 683329.564 3073371.863 436223.0903 948031.2448 881124.5555 829287.9747 926514.6542 1738121.489 1838652.932 1052493.438 761800.7271 1082882.461 718657.931 709795.7149 1624642.171 1661355.71 1379798.451 1684103.755 885890.411 951143.878 825320.8148 852882.6812 1815457.051 1579172.946 1309944.937 1450062.659 543421.1848 875443.0384 1289033.858 967215.6863 1100333.212 1071920.045 1386082.096 1363993.463 890912.7545 523192.4703 1399556.65 1168889.594 1140026.424 1294444.83 1352384.582 2251112.511 2359473.12 1599547.396 1475066.354 3919306.739 1621078.037 1310867.734 1381780.962 1072741.807 1629460.201 1452998.379 3306228.374 2930099.857 3410000 4900000 4290000 2950000 1850000 4580000 3470000 6200000 3470000 4150000 3870000 6140000 2880000 4430000 3990000 4390000 8390000 3030000 4550000 4150000 5290000 3720000 4330000 4680000 3840000 4040000 3750000 4360000 LPC181 524593.1275 306732.7478 1354241.396 288585.2141 450845.5116 400970.355 424011.4773 462507.7198 768961.3588 733514.2963 557555.3056 372150.9691 470875.8082 375062.8966 345511.9041 1235983.346 1264723.003 1135554.749 1198932.59 671232.8767 914426.9268 831113.8949 754972.0652 1430224.096 988440.4906 1038936.657 913487.1265 390445.3775 573885.6153 576545.2756 534189.2757 534658.9511 669620.8143 678278.5663 563174.6204 435077.8718 289715.7002 583766.8824 561687.0308 545649.4976 561091.7287 919994.0366 1271402.981 1479699.347 999171.7232 1020178.137 2647436.68 977473.8536 801179.444 894063.4596 623900.8793 965233.3028 887358.1848 1894463.668 2012838.802 1770000 2990000 2520000 1880000 1120000 2710000 1780000 2710000 1670000 1870000 1790000 2860000 2000000 2470000 2220000 2520000 3210000 1730000 2530000 2010000 2680000 1880000 2270000 1830000 1730000 1920000 1930000 2100000 LPC182 444255.9115 232105.2204 1350022.05 218111.5451 319598.045 300690.6256 308420.1867 390845.2595 1060416.814 830285.5032 703787.0266 293858.9735 368819.7419 297290.9732 238729.6818 665065.2574 627799.0087 552225.3224 545484.3384 128054.7945 252501.8904 213861.2078 156453.9451 629089.1552 413814.9944 487900.8028 363405.5949 84418.59048 135116.2558 103972.3543 97605.71562 465525.5896 719002.8803 692510.6593 557315.5419 377285.9838 297043.8032 586717.7548 722189.1703 594926.4834 644323.7859 415560.5746 488407.3255 770420.6548 327763.2308 364325.6178 805447.1625 242880.1287 317523.1676 394268.1679 226059.1527 257639.5242 286385.7374 443252.5952 642225.3923 LPE160 73281.77053 40387.32908 149854.3041 30260.34846 4856.056341 51459.79663 27877.24248 2915.16307 79938.02534 94022.67561 67904.012 40382.98112 44515.5701 31382.81379 30524.75248 54412.23557 58205.24142 46171.74787 58147.23095 40616.43836 52962.74504 32866.07456 44522.2582 56520.7807 73971.10356 43636.19856 41078.12883 16004.20117 26879.86248 29810.4252 29588.0819 64753.33693 61424.70577 69374.82326 61934.36524 51433.6879 27008.32009 63418.46461 57098.74181 48629.72918 56167.14545 46112.78859 65851.58888 65851.33031 48780.52343 48626.55432 212472.1364 64167.33709 38003.36984 39498.46469 30495.60352 44730.10064 42876.82334 103235.2941 101554.9215 154803.9632 175586.6823 187809.9656 126479.852 111009.2526 166798.6847 103913.0624 205767.1452 126231.5883 134665.947 122675.084 237630.0264 129492.7231 176473.2788 143495.7109 205194.6739 309659.3137 149228.098 189023.4673 128023.6305 121351.5322 119357.7036 140722.2455 111005.3455 133643.8066 116282.7734 110591.1773 127813.2673 LPE161 5456.408853 3872.011836 12607.40682 47735.41115 6854.366553 82495.56023 40430.59771 3083.368729 5020.532441 4718.884712 4323.209599 3727.543756 3867.908424 3570.137625 2192.776336 2560.078786 3360.428027 2515.3532 3486.168081 2068.493151 2424.484395 1864.406286 5385.083878 3350.404668 2398.339225 2163.771342 2545.723723 977.2410295 1191.22903 1938.405906 828.2195545 9132.943226 8605.648027 8373.951334 9577.640236 4799.785637 2592.785095 5410.213871 5823.310724 6161.149766 6095.402396 2952.894814 4080.399897 8639.694537 5965.360611 4236.76909 15467.71758 6410.297667 2674.810447 3127.942682 2137.490008 2241.537054 2667.747164 4975.778547 7097.00428 7343.478722 9756.29833 9857.564435 4461.934619 5232.55765 10334.8005 6471.500503 9958.67025 5149.101495 5804.061448 6491.896933 12931.67674 8637.623464 10053.73387 7870.478559 9932.795991 13835.51804 7958.594082 9219.803159 6253.278567 6234.153058 5341.34223 4696.756882 7003.484135 4044.949195 5945.848244 4172.063469 6490.682209 LPE180 59585.90565 34109.77035 110496.2415 53987.63505 4846.110774 76777.13206 35135.04592 3298.088877 71873.48119 78676.70907 52080.98988 54864.73751 68290.18199 38432.37088 48684.53169 70006.8692 75737.3804 58587.89431 75508.09474 88438.35616 82744.2721 68493.51731 89258.83687 63589.61841 111841.8904 43850.94363 35722.84327 28858.67933 125409.9452 43089.17323 128160.1907 51855.94012 51976.27048 62338.33507 49364.68895 46031.40271 22458.07939 64236.27783 47502.43303 40435.2168 50427.86031 67719.01151 125265.5198 70752.26568 71076.4514 89234.45869 395105.0584 94851.16653 37144.06066 49723.64381 38649.08074 79551.69259 66474.87844 179757.7855 146077.0328 359576.506 436855.1997 493806.8206 339019.9088 272799.5548 412419.2559 230232.9232 489194.2343 246078.3079 271879.053 278179.6781 502591.8983 248113.8314 398803.8562 367017.4599 443985.6237 795021.1615 321458.599 466498.0941 310817.2954 305735.0225 256707.5436 276176.8994 320685.7363 271647.6176 231100.797 244111.6013 318288.3608 LPE181 43619.25451 24849.37883 84184.39787 51803.98665 5335.934347 75611.55063 30347.13241 3008.201477 51379.63523 48265.35522 29062.61717 23366.91735 27352.34474 17888.48736 19152.78587 59886.04854 67159.89395 55171.5419 65798.00701 49520.54795 60510.11834 49598.42098 61419.73547 56281.41265 56784.58913 39783.67197 34654.92709 18469.85546 24729.03228 29288.5 24920.60824 43018.9445 37958.34803 46302.92103 36670.01898 31244.76368 15740.08357 37712.14998 31424.03609 32301.76637 31835.22665 57082.20411 101844.5758 71789.92301 65238.4961 65244.91584 204218.7367 71826.22687 36444.81887 41402.25179 32462.03038 55343.09241 45956.23987 122266.436 98330.95578 152106.9003 209009.1859 240054.078 130393.4414 110284.662 203916.0633 100579.4646 190118.9685 112610.2631 124996.4562 112001.74 263089.5214 145477.2625 195991.8431 184313.2425 230337.9869 323728.4681 176301.4865 199086.8181 124345.1329 129334.6647 123064.8845 149208.9021 114732.6936 138483.5992 102637.829 114803.0936 146722.8868 LPE182 5074.584741 2859.776756 13824.2663 53956.73528 5984.864886 87344.24555 37300.46051 2673.099722 7222.718927 4995.455676 4338.207724 1596.010236 1640.810939 1472.280153 1383.4079 3473.185623 3910.360492 3113.979726 3943.348602 2035.616438 2287.524339 2701.506364 3660.368073 4024.375333 3159.209537 2551.600941 1690.867289 749.3183525 753.0111658 1134.155591 594.0234094 4575.941936 4467.4309 5149.188908 4637.265289 3121.745182 1541.287525 4414.505194 3389.709364 2530.406802 4713.998701 2215.170023 4550.472993 6396.758317 2382.304633 3318.691775 7817.450915 3418.342719 3363.942713 3079.836233 1820.943245 1609.332113 1912.479741 4448.096886 4229.671897 LPA160 17099.07979 13190.24536 33754.7706 5774.890253 13433.68147 9558.515242 32962.95978 8918.827957 14898.18419 19176.73207 13884.51444 6536.40109 7704.491077 4923.350192 5520.028768 33561.05169 15177.8927 13543.03284 26351.19211 12195.89041 10400.22212 14975.11212 11866.58617 20832.50056 30598.90484 16423.70308 15076.46375 5630.411778 8919.878861 6860.28189 7601.607977 36579.12452 22235.09823 35403.43618 27100.19085 23739.46555 21783.21223 45080.90006 23413.02061 22165.48429 22675.55946 14541.62664 30988.983 35312.27701 31711.70343 19382.55451 80925.64239 16106.19469 17944.39764 20716.47902 11270.98321 34263.49497 16685.57536 34930.79585 27089.87161 21421.34076 46604.07915 30345.71309 40209.70579 17293.86186 42486.12524 36465.31227 56973.49469 36784.79176 37198.67424 73590.50593 56319.84595 38468.02246 51281.21961 58709.83146 41967.13804 62758.84217 44406.87391 49302.63757 48941.6928 42873.33754 42565.19339 50385.81147 34207.86738 47703.54901 69633.99455 44393.95058 42682.49681 LPA161 671.1566686 1243.03602 2405.027405 454.1282449 276.1478587 261.9157969 3948.48537 766.8482939 921.763248 1214.507277 1611.92351 160.5061334 949.9952405 168.8680766 37.59822453 2124.346376 1581.055837 983.6035521 2747.748231 158.3561644 677.0780639 691.7903179 1149.434535 980.660978 1757.51542 1395.842966 1418.129871 63.95666676 193.3541195 107.1039055 265.8609444 2898.510886 1792.898208 1906.746862 2213.169232 1915.653605 1865.087425 2944.127604 1676.18345 1273.141453 2494.477176 1317.793338 1847.208062 4022.917634 2295.913366 2330.056982 4425.092004 1584.070796 1739.679865 1836.233367 1303.756994 2261.665142 1235.818476 3693.771626 1475.035663 1015.300238 5575.142217 110.7501127 2847.771179 1252.438412 4612.68009 2945.304213 2003.873339 1578.812291 3531.174242 2375.856985 3041.187426 3301.099327 2524.915395 4197.546456 3741.068101 4653.405235 6216.392071 1330.654846 3950.856263 352.0079001 2459.898196 1646.988179 2867.188796 237.9105986 2470.533682 2635.049132 2108.351636 LPA180 33474.82819 37330.7761 69366.05358 86722.11888 81778.03422 59038.76216 54755.6297 29909.33228 16850.65278 17350.10396 13569.55381 8114.309131 11147.0285 6318.141916 7723.687369 32848.91285 42352.09979 27774.43519 88037.2402 68972.60274 45867.04853 69516.96147 109686.9619 16583.71768 32304.60162 10999.24257 17782.89839 6076.184032 35383.91416 19881.70866 29608.64346 43504.29858 36351.78482 38815.60256 38818.34774 36510.48958 18310.03225 25310.05461 20207.20527 19686.36952 35504.0626 46644.96156 92705.03145 70401.05859 51668.95872 44750.04342 281885.3443 50691.8745 22325.18955 20245.64995 17505.9952 39405.3065 21709.88655 33944.63668 40870.18545 228491.2678 245442.1391 242583.3759 178615.6512 112655.5132 273524.7889 45495.19257 100446.5032 38516.54387 67092.81145 78940.01202 305191.292 196538.2677 270872.0168 256442.8805 230598.5749 358178.1472 239741.9795 241960.359 57287.51594 88854.56396 48306.11302 83782.82008 56510.73753 61684.70099 65552.74577 72756.52619 63829.40361 LPA181 13885.59115 13031.46339 22210.63905 12342.44998 15705.84718 11301.15409 31708.06962 6172.266717 11707.73734 19777.9733 10104.98688 6589.19916 3455.72722 7402.979923 2874.278163 22287.53172 20081.05162 15745.81529 28777.04793 12573.9726 13035.97469 19850.95455 24049.01304 36915.04139 32002.32624 20100.13871 24316.03268 2207.061279 5139.932669 4153.553543 2732.631052 24847.76128 13998.16963 25184.61665 21522.34816 19959.50463 14894.79541 26380.79975 15007.44325 11723.89252 16513.90269 15439.66854 31002.76814 31848.09793 18971.17316 12667.14269 95654.7865 25808.52776 24052.23252 20235.41453 13964.82814 15059.46935 16799.02755 22058.82353 14436.51926 23536.91623 47737.0507 47255.80648 51469.87644 28367.62739 57883.69285 32265.81862 63695.81312 38388.84724 55975.12626 93483.23205 69014.81959 60638.29313 58563.4299 58883.40806 45235.07092 104729.928 68198.02684 32979.70625 60617.5249 40594.50127 41944.21982 41874.9309 49812.40678 83362.7388 97520.33099 64301.59042 61162.06854 LPG160 8946.779266 7717.938063 19729.66341 15878.87731 17001.38026 12522.33835 13423.78979 11477.98737 3846.929043 6132.66051 4769.403825 2060.633254 3231.500644 2011.864215 1897.594907 14146.21564 20366.96784 13435.95313 20659.76114 13694.52055 16420.6365 16172.34867 28470.7828 11856.1987 7664.839978 4432.338279 7093.266799 2642.309399 3268.158905 4974.068504 3651.732693 13157.83071 11726.59459 14364.69009 14139.90932 9865.042517 2949.305828 6893.238057 5683.804914 6698.49484 11139.01661 13543.8023 19064.84141 30730.62081 19206.7857 20237.54514 65011.39472 27699.11504 8395.956192 8396.110542 6872.102318 7412.625801 8824.959481 17698.96194 17803.13837 LPG161 9770.902737 6804.941716 29113.48964 4552.114749 6706.875095 7888.672044 7895.203288 7526.057547 13638.98344 14401.1589 9767.529059 6184.916794 8738.241538 6164.110038 5038.488555 10217.38186 11102.0658 9774.847119 10749.74023 5173.972603 7822.75043 5206.048003 5576.844301 13703.82084 9551.901989 9380.06473 11710.43382 4170.564025 5352.809708 6851.785433 6121.175804 10837.60146 8842.681943 11942.58234 11647.84795 7734.717721 3848.106182 12714.04475 9229.929883 9550.087448 10244.58256 8867.332254 12900.12913 15841.03638 8796.201721 9355.091622 23807.88381 9452.936444 8946.925021 8026.612078 6258.992806 9038.426349 8938.411669 20034.60208 18145.50642 LPG180 1695.085614 699.7748398 2096.171254 878.6906829 1034.433336 1531.680015 1062.061262 1002.82468 1133.988094 1272.340957 956.88039 217.8297525 408.3891376 588.7230651 211.2519634 1937.86256 2433.937823 2276.718434 1911.361127 957.9452055 1964.065483 1875.026933 1846.540073 1321.760449 1703.969496 1363.201715 876.8429437 213.7150959 180.5594373 998.8191732 640.4925303 1891.105224 1036.364957 1273.816518 1162.441164 1331.726116 511.6038423 1101.096979 1165.36672 658.2477154 1420.32814 1992.987804 3830.888957 2546.251439 1607.401148 1458.464595 8905.206673 4081.255028 881.2131424 757.3183214 476.2589928 1655.077768 1060.777958 2678.200692 2396.57632 LPG181 4316.272568 2852.971814 9461.462198 2509.907614 3957.355275 4486.589374 6550.173133 2635.619356 5070.758988 5754.737453 4529.433821 2253.723339 3312.288161 2970.074789 2302.959267 10374.29381 12020.64769 10351.0379 8377.19992 7205.479452 6789.721923 6297.078093 8113.721896 13771.1431 9206.444413 10191.8011 8972.589884 2277.723323 4204.597282 5312.712992 4262.410964 10222.03043 5550.544213 6131.291719 5529.407634 4679.067232 3800.388302 7296.242923 5526.684733 6185.574543 5047.755109 6557.701527 10917.82675 17145.29182 18203.25078 10201.78137 27574.82009 12695.09252 7147.430497 7466.734903 5967.226219 10137.23696 9829.821718 22024.22145 20870.18545 LPG182 1243.892836 641.9328352 2794.895005 296.3589823 658.330117 455.4928152 949.8281279 723.9707549 1573.293525 1688.05632 1210.72366 444.1071962 407.7296476 482.4127203 232.4723796 2569.131398 2970.486976 2591.838701 2580.470811 236.0273973 726.3254031 253.4472553 333.5503357 3005.565072 2371.13444 1763.916019 2050.503768 242.881982 328.2497773 92.38075984 361.2665733 1195.036447 1821.210592 1325.087412 1324.151729 817.1707423 506.4912123 1316.932222 1269.64379 1152.238812 1217.42412 1660.379693 2784.597227 3338.063798 1997.470807 2731.819568 5519.196531 1913.113435 1806.234204 1243.602866 1161.470823 1741.079597 1405.186386 3695.50173 2573.466476 LPI160 3379.499126 2120.873501 8212.535686 4422.764344 7885.810197 8607.714845 4957.699849 6401.646559 2064.240336 2033.340567 2057.742782 3195.037505 4553.777949 3688.26023 2644.390321 2397.73527 2829.962198 1799.448904 8363.871041 4997.260274 5806.232159 8158.587839 6004.357243 2798.362104 3380.734208 1748.024883 1797.658907 1304.992636 3500.889762 3663.186614 2134.289716 9671.567875 3107.11959 4799.13246 6777.000738 3010.312808 1728.409783 4581.440264 2289.868101 2537.734235 3765.732975 2019.596453 4430.542321 8302.855005 4584.845619 4486.625574 12892.23361 4607.401448 4593.934288 4637.666325 3485.211831 2622.140897 2051.863857 7148.788927 2937.232525 12098.39566 19033.83404 20897.15522 15774.23519 10996.94903 26167.18308 6787.425471 22075.28942 8695.253804 13496.27104 8968.625975 22487.3248 11328.83458 17934.51131 16877.80753 23436.73412 29596.3961 12775.17936 20387.01116 8480.7545 16030.6857 9885.949289 8387.436674 8754.348583 8535.813384 10928.64664 11820.8465 11410.50776 LPI161 36.93733256 47.08452589 105.1461104 26.4244399 31.42165999 47.40631355 36.02064988 40.1339762 56.85991107 31.76844119 28.9463817 30.33626262 34.24401448 34.29335479 28.25307972 50.09112192 31.76697838 13.32221371 85.34246575 30.26234428 20.05371236 23.42861168 31.07296493 35.85849644 13.55041402 8.344403894 30.43729945 114.4903457 66.68504724 41.90445512 143.2978325 49.88905516 36.70288815 209.8331295 11.07222657 21.21059767 5.174144074 153.7382214 50.2356582 20.43947434 22.41778672 57.20830937 98.81690537 29.72208637 41.39648795 307.492046 16.70957361 69.9831508 21.22824974 16.57873701 191.0338518 26.67747164 107.7854671 207.4179743 LPI180 17899.48748 8619.59284 19712.78603 36970.00248 78110.67904 77445.66359 43196.50064 58004.61484 13759.24418 11549.55766 8582.677165 39598.55265 57458.05993 41976.04904 34007.07718 10682.08263 13699.64503 10381.6321 27490.81119 71931.50685 58645.13034 97613.40006 49541.86927 10360.14839 17484.47159 8293.454667 5611.79484 28332.47262 42222.45119 53066.44094 27387.9952 22225.66546 12312.59511 12800.04384 13975.85512 11520.14101 6721.404244 13995.5665 9511.759803 8078.494689 9789.08374 13384.15041 39315.20441 22860.38909 19294.04961 21781.5088 174866.2613 20257.44167 12771.69334 14708.29069 11694.64428 18792.31473 15737.43922 32058.82353 19572.03994 232857.7538 149031.5689 218653.3475 118027.9136 98492.2001 251656.0692 69983.85057 164513.0716 75889.84303 151237.6347 89182.85417 197618.7622 93874.83232 138365.0608 152836.3006 143966.4265 382523.7529 101782.7873 174643.6045 111869.9181 131849.3231 74437.60079 114094.5941 88709.2411 110579.21 77610.10625 90632.59151 94144.84299 LPI181 2450.433314 2142.422483 5410.889727 3094.214616 12486.94576 5269.514076 4109.323404 7379.134511 2022.502783 1645.683128 2188.976378 6738.542273 10011.0571 3878.201379 3917.615291 2909.509624 3668.244208 3382.188886 7184.265325 6387.671233 6335.131099 7459.556171 5232.803542 5441.134976 3989.171364 4018.309781 2759.306959 2951.267909 7034.869219 7983.027953 4424.847272 5132.323442 2951.072261 4465.87165 5066.149831 2447.14233 1382.455153 3791.449552 3393.936813 4905.716276 4059.736759 3467.106955 5625.713507 5691.151335 4966.188888 4997.129686 16633.77482 4631.536605 4595.619208 4393.039918 3517.985612 5318.389753 4025.121556 9711.072664 6945.791726 12081.41206 23737.83719 17684.54422 12624.63242 10825.47857 28265.50724 9661.59283 25960.04731 13631.78382 16065.90909 10039.34171 20594.55328 14292.45381 16955.24444 20580.02641 21069.82607 30029.64132 15383.78164 20720.04242 15565.27303 27422.678 14149.75234 13023.18203 13613.25443 13592.10639 15367.43446 23495.41934 18190.12954 LPI182 579.8509027 587.4933015 2256.506414 174.3363095 559.7699466 461.2867551 67.09243717 428.6254687 258.7728289 686.5602196 612.2984627 551.966111 506.1585193 419.0990038 419.6473324 124.9260511 167.169736 330.4683577 469.6430217 324.2465753 204.4201686 329.4331563 83.65266451 426.5239433 426.0787384 414.4150393 278.0246492 95.46893135 416.0477688 321.8943307 83.25374817 650.4928454 415.1385678 261.4815586 1141.348482 356.5289729 186.0656479 510.4166242 496.6547767 311.415895 515.3762108 100.5806929 161.0103743 407.5598698 139.0114022 137.8776148 597.8424157 335.4786806 290.5644482 265.6090072 296.882494 265.5077768 383.63047 138.200692 404.1369472 LPS160 2046.672103 1699.534193 3572.942468 3611.616237 2661.822196 1598.533168 1878.800335 1193.374862 438.0320822 455.969894 708.2864642 407.2993986 787.1012284 372.8894406 348.3684986 2167.195408 2931.553704 2346.065289 3242.249611 1579.452055 1997.576986 2123.163865 4431.921775 2228.366936 1714.333223 1418.605943 954.3192158 389.3929641 891.9878861 1106.602795 554.9564492 3575.639017 2121.453553 2845.534608 2870.167229 1374.332612 661.5743224 2294.935664 1143.524901 1870.327228 2752.869234 1646.410152 2431.697777 3759.512312 4022.866065 2903.647781 9140.111126 2722.445696 2040.438079 2287.615148 1041.566747 1640.439158 845.2188006 3591.695502 1677.603424 6599.011578 19098.91728 16208.28788 7808.376104 9530.118327 13283.01116 5452.603471 5302.933194 1838.015156 3076.813973 3262.806801 20595.12405 14329.71553 14062.98469 13321.49265 13760.09008 18334.79888 18553.52961 15064.46042 1990.214297 2319.685787 3232.837516 2836.52941 1947.845194 2542.897319 3140.422886 3678.014335 2439.188213 LPS161 38.49071637 56.46400389 182.9508566 26.15044643 32.03952961 15.73277532 102.3177341 9.795868528 9.005407634 35.69655053 52.98087739 98.41560284 128.1718674 56.36810728 43.16178235 32.60750985 17.75722196 14.53734436 68.44378932 111.7671233 178.0480727 96.74443804 937.0316668 58.88454019 28.19365646 32.99343281 179.4517977 45.9904663 932.9088093 41.32919291 168.3991597 76.76880987 82.69849978 25.75036444 35.42789435 30.45818221 1.740339253 12.87423497 25.43515029 94.21857373 82.98360327 62.86293308 125.5412225 91.72890763 92.49974032 60.80394511 161.6608217 20.49879324 23.16764954 7.723643808 32.20623501 89.44190302 245.7860616 116.1418685 229.1012839 LPS180 33042.01514 42241.6757 66091.84083 90354.12533 74971.50273 66229.19016 55992.84535 39684.21181 14579.84692 13759.83493 11852.26847 6378.00688 8680.53617 5377.885977 6995.935917 30477.1284 47693.25802 32664.40827 82972.26651 60561.64384 52904.46417 71583.16004 118214.6607 11220.37732 20999.50243 8894.740868 10715.806 2313.806068 4568.58393 11217.75039 6610.540883 42172.53434 38899.89942 35315.03809 38419.93041 34997.41274 9325.437125 20108.08802 15430.18813 13726.72416 28423.12639 40531.62447 56863.681 56448.55854 40638.80101 41047.851 249929.8736 48045.05229 12325.18955 12016.37666 9328.53717 12689.84446 10623.98703 18564.01384 17132.66762 324047.4872 332820.7837 371714.0564 268809.1404 163857.5861 394002.3277 49428.28616 82626.86797 41414.01815 51269.93266 76330.59962 430612 307087.9847 372371.6012 394415.027 338139.3817 527830.9177 379203.2557 317403.1908 54360.06615 82183.68714 53998.35522 61729.18657 52178.86834 64941.21553 63143.55606 81501.81969 52478.70819 LPS181 65455.56203 55789.1805 149668.6528 52829.76397 62215.48472 45712.70034 39891.36741 40388.84269 57406.82085 54426.64626 69553.80577 31452.56467 39256.13793 35398.98238 26471.10888 78214.5711 89911.52469 72865.18797 76507.7606 53356.16438 54958.86501 74518.32064 97324.05466 96869.25755 65161.93536 64981.85868 66064.22657 17868.47636 28821.1246 34022.24016 27881.47259 90915.1056 74468.15546 78470.98701 97338.82328 44037.63719 36947.27282 88863.41624 93356.16103 95928.30806 90602.85627 58346.11493 83344.92493 134911.4164 93546.90719 86578.17713 268976.1806 75728.07723 87952.82224 84063.45957 61286.97042 82415.37054 64149.10859 141314.8789 116833.0956 217805.9486 395487.8698 358116.498 229710.6276 167598.5034 430052.5752 184882.458 322368.7819 180711.9929 190931.6498 225949.3549 439955.1307 352050.8687 365059.9833 422213.8398 338166.9194 535627.8005 339740.508 338483.0431 208765.1301 341349.8277 261628.5469 195213.5513 200038.8305 212311.4862 237124.1594 278321.7658 248224.31 pLPE160_alkylLPE161 99309.84275 86082.5127 231220.1786 46770.04795 89900.03006 80134.64597 74109.21735 94735.37378 92883.74095 91789.49391 60067.49156 38331.39896 48423.04792 37241.69502 33816.63755 97285.40788 99401.5097 84796.92623 98500.40956 78684.93151 75022.05618 47609.46347 68695.35152 72603.32153 77252.95054 41999.84111 71508.50514 21085.85452 29394.67932 26108.39764 52082.4263 127257.472 101661.2131 116508.6864 126556.0945 91494.7188 25726.75417 66107.97407 70450.43428 53618.48969 93501.48513 105104.1633 135838.7182 162513.1012 104891.215 110318.6936 398067.8173 127996.782 68062.34204 80562.9478 56035.17186 65571.82068 57236.62885 153373.7024 114893.01 213091.1991 279267.626 344785.7665 203297.0256 171289.5514 317613.2558 121635.8431 204466.2803 120435.4739 132158.3207 138631.6932 322901.9487 162711.3483 289613.5495 266369.2338 333136.8354 501969.8126 211851.7605 263766.3985 162324.57 137113.2703 127081.1295 157324.3532 108490.4805 140057.0493 106063.8164 101545.0012 146671.5593 pLPE161 792.7000582 965.1675667 3539.187697 503.6382275 909.1652525 987.1982248 901.5767176 996.2281354 625.2143964 748.974785 425.5718035 343.9417144 444.3313386 439.8885824 338.9825453 919.7454194 821.8570356 839.3009055 833.7213285 501.9178082 872.7561012 383.7915581 952.7109013 499.2319883 357.8940492 348.1876592 561.179484 171.6937317 366.5235248 416.6905118 384.2955182 1537.151883 1064.677342 919.3401655 1513.20466 906.7536311 205.5618103 665.0423409 622.9145809 532.2158708 768.302283 995.828686 1188.967875 2155.134447 1270.562471 1172.084239 3910.841714 1039.420756 657.0345409 838.9969294 493.5251799 853.0649588 454.376013 858.4775087 1030.670471 1945.81695 2134.182723 3433.493482 1417.362635 1638.443666 2115.520869 1284.12914 1664.902599 1036.851174 996.5025253 1271.621967 2203.190656 1566.204478 2601.418605 1690.751539 2365.02907 2636.859676 1646.938159 1996.030895 1515.000885 1118.429906 1030.793506 1036.98671 525.2714535 698.9487581 837.4635769 640.4505423 1198.87452 pLPE180_alkylLPE181 17253.23238 28648.80462 82260.37594 11106.2934 25203.10121 23264.89722 20961.96799 24257.29305 17161.91588 17825.37084 11683.53956 14462.14568 14393.36767 9061.421303 10059.29343 20808.93836 23104.46352 18973.50346 21826.03798 26383.56164 23807.73739 19908.88535 17032.83757 28222.98909 29208.43809 9109.48594 29179.23921 6954.197511 11272.5562 8480.677559 29300.22009 15702.98015 18916.6234 19703.93489 37544.97469 12601.69052 4526.381762 11137.43575 8884.688231 4663.300373 20157.89325 16497.36233 32036.65325 53415.40636 15925.66284 16800.98087 86068.14529 17506.03379 27868.57624 32917.09314 25427.65787 15443.73285 11669.36791 30484.42907 20570.61341 120676.7405 108887.0677 149715.7799 125380.3874 76733.50159 130130.8128 55072.622 108039.4819 57916.58922 82333.27441 68736.16357 152341.5459 58814.1377 125108.8433 92343.56217 153206.1794 243473.504 91944.76455 120596.5399 74568.39539 69133.9736 51260.02188 68801.31044 78787.34569 104904.2886 65529.6498 58085.68734 83256.48274 pLPE181_alkylLPE182 53313.08096 100599.7217 178731.5103 29349.16088 58189.36654 46990.33837 43496.9673 51213.17247 38497.58707 33640.87815 24810.64867 19535.28597 24153.81859 20515.5341 18540.65848 68920.55571 76954.04515 69244.87422 74508.42888 68150.68493 75386.31165 57515.63048 56140.68383 61480.18747 33176.882 25842.42192 55489.76241 18965.99321 23284.11559 19019.9252 38779.09831 63687.92554 53121.93441 54665.38061 69980.83298 45102.79959 8875.525685 25731.60781 28049.1228 19344.42266 44365.5851 74171.60888 99652.73938 127855.3465 65430.47669 70291.85081 269611.0575 94288.01287 70488.62679 68065.50665 47585.93125 36980.78683 32730.95624 98235.29412 61754.63623 116742.4134 146267.7677 235450.1976 149907.8555 96699.55135 201968.0882 63228.33265 103586.3657 60683.52456 74307.98401 57039.4522 191487.4048 103753.4337 151742.0919 154118.2163 158754.1215 280525.6642 112513.4988 180812.4717 90549.10782 69407.60349 49966.08654 81805.5847 58369.84312 65397.80339 49140.04947 50211.77541 68889.5809 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name quantified m/z (Q1) quantified m/z (Q3) Palmitic acid 255.201 255.2 Palmitoleic acid 253.201 253.2 Stearic acid 283.301 283.3 oleic acid 281.201 281.2 Linoleic acid 279.001 279 AA 303.2 259.1 EPA 301.2 257.2 DPA 329.2 285.2 DHA 327.2 283.2 LPC160 540.4 480.4 LPC161 538.4 478.4 LPC180 568.4 508.4 LPC181 566.4 506.4 LPC182 564.4 504.4 LPE160 452.28 196 LPE161 450.26 196 LPE180 480.3 196 LPE181 478.29 196 LPE182 476.28 196 LPA160 409.1 152.8 LPA161 407.2 152.8 LPA180 437.2 152.8 LPA181 435.1 152.8 LPG160 483.3 153 LPG161 481.3 153 LPG180 511.3 152.3 LPG181 509.3 152.7 LPG182 507.3 153 LPI160 571.4 240.9 LPI161 569.3 241 LPI180 599.2 152.9 LPI181 597.3 241 LPI182 595.3 241 LPS160 496.27 152.8 LPS161 494.27 152.8 LPS180 524.3 152.8 LPS181 522.2 152.8 pLPE160_alkylLPE161 436.28 196 pLPE161 434.3 196 pLPE180_alkylLPE181 464.19 196 pLPE181_alkylLPE182 462.3 196 METABOLITES_END #END