#METABOLOMICS WORKBENCH rkuna_20240813_140418 DATATRACK_ID:5102 STUDY_ID:ST003423 ANALYSIS_ID:AN005622 PROJECT_ID:PR002116
VERSION             	1
CREATED_ON             	August 20, 2024, 7:06 pm
#PROJECT
PR:PROJECT_TITLE                 	Bempedoic acid suppresses diet-induced hepatic steatosis independent of ACLY
PR:PROJECT_SUMMARY               	ATP citrate lyase (ACLY) synthesizes acetyl-CoA for de novo lipogenesis (DNL),
PR:PROJECT_SUMMARY               	which is elevated in metabolic dysfunction-associated steatotic liver disease.
PR:PROJECT_SUMMARY               	Hepatic ACLY is inhibited by the LDL-cholesterol lowering drug bempedoic acid
PR:PROJECT_SUMMARY               	(BPA), which also improves steatosis in mice. Indeed, BPA potently suppresses
PR:PROJECT_SUMMARY               	hepatic DNL and increases fat catabolism. However, it is unclear if ACLY is the
PR:PROJECT_SUMMARY               	relevant molecular target in reducing liver triglyceride, particularly since the
PR:PROJECT_SUMMARY               	acetyl-CoA synthetase ACSS2 can compensate for ACLY deficiency to provision
PR:PROJECT_SUMMARY               	acetyl-CoA for DNL. We show that on a Western diet, loss of hepatic ACLY alone
PR:PROJECT_SUMMARY               	or ACLY and ACSS2 together unexpectedly exacerbates steatosis, linked to reduced
PR:PROJECT_SUMMARY               	hepatic abundance of endogenous PPARa (Peroxisome proliferator-activated
PR:PROJECT_SUMMARY               	receptor alpha) ligands and lower expression of PPARa target genes controlling
PR:PROJECT_SUMMARY               	fatty acid oxidation. Importantly, BPA treatment ameliorates Western
PR:PROJECT_SUMMARY               	diet-mediated triglyceride accumulation in both WT and liver ACLY knockout mice,
PR:PROJECT_SUMMARY               	indicating that its primary effects on hepatic lipid metabolism are independent
PR:PROJECT_SUMMARY               	of ACLY. Together, these data indicate that hepatic ACLY plays an unexpected
PR:PROJECT_SUMMARY               	role in restraining diet-dependent lipid accumulation, and that BPA improves
PR:PROJECT_SUMMARY               	steatosis independent of ACLY.
PR:INSTITUTE                     	Salk Institute for Biological Studies
PR:DEPARTMENT                    	Molecular and Cell Biology Laboratory
PR:LABORATORY                    	Metallo Lab
PR:LAST_NAME                     	Kuna
PR:FIRST_NAME                    	Ramya
PR:ADDRESS                       	10010 N Torrey Pines Rd, La Jolla, California, 92037, USA
PR:EMAIL                         	rkuna@salk.edu
PR:PHONE                         	8582038321
#STUDY
ST:STUDY_TITLE                   	Impact of ACLY and ACSS2 on the development of MASLD on longterm Western diet,
ST:STUDY_SUMMARY                 	To further assess the impact of ACLY and ACSS2 on the development of MASLD on
ST:STUDY_SUMMARY                 	Western diet, we also carried out longer term experiments, in which mice
ST:STUDY_SUMMARY                 	remained on diet for 22 weeks. Exacerbated steatosis was apparent in the liver
ST:STUDY_SUMMARY                 	ACLY KO and DKO mice, both histologically and by TAG quantification. Further
ST:STUDY_SUMMARY                 	lipid analysis by LC-MS revealed elevated DAGs and cholesterol esters (CEs) in
ST:STUDY_SUMMARY                 	ACLY-deficient and DKO livers, along with reduced abundance of
ST:STUDY_SUMMARY                 	phosphatidylcholines (PCs). Together the data indicate that ACLY deficiency
ST:STUDY_SUMMARY                 	results in perturbed lipid metabolism in the liver, with accumulation of TAGs,
ST:STUDY_SUMMARY                 	DAGs, and CEs.
ST:INSTITUTE                     	Salk Institute for Biological Studies
ST:LAST_NAME                     	KUNA
ST:FIRST_NAME                    	RAMYA
ST:ADDRESS                       	10010 N Torrey Pines Rd, La Jolla, California, 92037, USA
ST:EMAIL                         	rkuna@salk.edu
ST:PHONE                         	8584534100
#SUBJECT
SU:SUBJECT_TYPE                  	Mammal
SU:SUBJECT_SPECIES               	Mus musculus
SU:TAXONOMY_ID                   	10090
#FACTORS
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data
SUBJECT_SAMPLE_FACTORS           	-	DF-1196_ACLY F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1196_1.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1207_ACLY F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1207_12.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1209_ACLY F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1209_14.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1214_ACLY F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1214_19.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1216_ACLY F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1216_21.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1224_ACLY F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1224_29.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1197_ACLY F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1197_2.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1208_ACLY F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1208_13.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1213_ACLY F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1213_18.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1215_ACLY F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1215_20.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1223_ACLY F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1223_28.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1225_ACLY F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1225_30.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1204_ACSS2F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1204_9.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1206_ACSS2F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1206_11.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1211_ACSS2F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1211_16.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1217_ACSS2F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1217_22.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1219_ACSS2F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1219_24.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1230_ACSS2F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1230_35.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1205_ACSS2F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1205_10.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1210_ACSS2F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1210_15.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1212_ACSS2F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1212_17.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1218_ACSS2F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1218_23.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1229_ACSS2F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1229_34.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1231_ACSS2F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1231_36.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1198_ACLY_ACSS2 F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1198_3.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1200_ACLY_ACSS2 F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1200_5.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1202_ACLY_ACSS2 F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1202_7.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1220_ACLY_ACSS2 F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1220_25.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1222_ACLY_ACSS2 F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1222_27.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1227_ACLY_ACSS2 F/F_GFP	Genotype:GFP | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1227_32.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1199_ACLY_ACSS2 F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1199_4.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1201_ACLY_ACSS2 F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1201_6.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1203_ACLY_ACSS2 F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1203_8.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1221_ACLY_ACSS2 F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1221_26.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1226_ACLY_ACSS2 F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1226_31.mzXML
SUBJECT_SAMPLE_FACTORS           	-	DF-1228_ACLY_ACSS2 F/F_CRE	Genotype:CRE | Sample source:Mouse liver	RAW_FILE_NAME(Raw file name)=DF-1228_33.mzXML
#COLLECTION
CO:COLLECTION_SUMMARY            	Liver samples were collected using Wollenberger clamps pre-cooled to the
CO:COLLECTION_SUMMARY            	temperature of liquid nitrogen and stored at -80 C until analysis.
CO:SAMPLE_TYPE                   	Liver
CO:STORAGE_CONDITIONS            	-80℃
#TREATMENT
TR:TREATMENT_SUMMARY             	BPA(Bempedoic acid) was first prepared as a disodium salt aqueous solution by
TR:TREATMENT_SUMMARY             	making a 2:1 molar ratio of NaOH to BPA in water. While stirring,
TR:TREATMENT_SUMMARY             	carboxymethylcellulose (Sigma-Aldrich C5678) was added at a final concentration
TR:TREATMENT_SUMMARY             	of 0.5% w/v. Tween-20 was added at a final concentration of 0.025%. pH was
TR:TREATMENT_SUMMARY             	measured and adjusted with HCl to pH 7. Vehicle solution was prepared with the
TR:TREATMENT_SUMMARY             	same method, excluding BPA. BPA or vehicle was administered to mice daily in the
TR:TREATMENT_SUMMARY             	morning by oral gavage at either 10 or 30 mg/kg body weight or equivalent
TR:TREATMENT_SUMMARY             	vehicle volume for indicated lengths of time. The last dose of BPA was
TR:TREATMENT_SUMMARY             	administered 2-4 hours prior to tissue collection.
TR:TREATMENT_COMPOUND            	BPA
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	Samples were extracted with 400 ul of methanol (-20 C), 100 ul of water
SP:SAMPLEPREP_SUMMARY            	(ice-cold), 400 saline (ice-cold), and 1000 ul of chloroform (-20 C).
SP:PROCESSING_STORAGE_CONDITIONS 	Room temperature
SP:EXTRACT_STORAGE               	4℃
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_SUMMARY        	30% to 43% B from 3-8 min, then from 43% to 50% B from 8-9 min, then 50-90% B
CH:CHROMATOGRAPHY_SUMMARY        	from 9-18 min, then 90-99% B from 18-26 min, then held at 99% B from 26-30 min,
CH:CHROMATOGRAPHY_SUMMARY        	before returning to 30% B in 6 min and held for a further 4 min
CH:CHROMATOGRAPHY_TYPE           	Reversed phase
CH:INSTRUMENT_NAME               	Thermo Vanquish
CH:COLUMN_NAME                   	Thermo Accucore C30 (150 x 2.1mm,2.6um)
CH:SOLVENT_A                     	40% water/60% acetonitrile; 0.1% formic acid; 10 mM ammonium formate
CH:SOLVENT_B                     	90% isopropanol/10% acetonitrile; 0.1% formic acid; 10 mM ammonium formate
CH:FLOW_GRADIENT                 	0 min, 30% B; 3 min, 30% B; 8 min, 43% B; 9 min, 50% B; 18 min, 90% B; 26 min,
CH:FLOW_GRADIENT                 	99% B; 30 min, 99%B; 36 min, 30% B
CH:FLOW_RATE                     	0.2 mL/min
CH:COLUMN_TEMPERATURE            	40
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:INSTRUMENT_NAME               	Thermo Q Exactive Orbitrap
MS:INSTRUMENT_TYPE               	Ion trap
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	POSITIVE
MS:MS_COMMENTS                   	El-MAVEN
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS	relative abundance/mg tissue
MS_METABOLITE_DATA_START
Samples	DF-1196_ACLY F/F_GFP	DF-1207_ACLY F/F_GFP	DF-1209_ACLY F/F_GFP	DF-1214_ACLY F/F_GFP	DF-1216_ACLY F/F_GFP	DF-1224_ACLY F/F_GFP	DF-1197_ACLY F/F_CRE	DF-1208_ACLY F/F_CRE	DF-1213_ACLY F/F_CRE	DF-1215_ACLY F/F_CRE	DF-1223_ACLY F/F_CRE	DF-1225_ACLY F/F_CRE	DF-1204_ACSS2F/F_GFP	DF-1206_ACSS2F/F_GFP	DF-1211_ACSS2F/F_GFP	DF-1217_ACSS2F/F_GFP	DF-1219_ACSS2F/F_GFP	DF-1230_ACSS2F/F_GFP	DF-1205_ACSS2F/F_CRE	DF-1210_ACSS2F/F_CRE	DF-1212_ACSS2F/F_CRE	DF-1218_ACSS2F/F_CRE	DF-1229_ACSS2F/F_CRE	DF-1231_ACSS2F/F_CRE	DF-1198_ACLY_ACSS2 F/F_GFP	DF-1200_ACLY_ACSS2 F/F_GFP	DF-1202_ACLY_ACSS2 F/F_GFP	DF-1220_ACLY_ACSS2 F/F_GFP	DF-1222_ACLY_ACSS2 F/F_GFP	DF-1227_ACLY_ACSS2 F/F_GFP	DF-1199_ACLY_ACSS2 F/F_CRE	DF-1201_ACLY_ACSS2 F/F_CRE	DF-1203_ACLY_ACSS2 F/F_CRE	DF-1221_ACLY_ACSS2 F/F_CRE	DF-1226_ACLY_ACSS2 F/F_CRE	DF-1228_ACLY_ACSS2 F/F_CRE
Factors	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:GFP | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver	Genotype:CRE | Sample source:Mouse liver
PC 32:0	0.863922977	1.31423511	1.288579235	0.894328031	1.210560866	0.842032692	1.625744438	1.602532568	1.213403	1.513649475	1.858465025	1.302725449	0.865567999	1.091960572	1.083295123	0.900478649	1.225333428	1.488814047	0.856205858	0.949180636	0.941674752	0.813684689	1.079699467	0.880163744	1.195493003	1.38527994	1.045749294	0.909626649	0.909357037	0.810412103	1.098077139	1.861268981	1.753261443	1.05766658	1.23791511	1.555808525
PC 32:1	1.208361753	2.592946669	1.042868706	1.86517392	2.570712043	2.249948728	1.189076771	2.334435394	2.93598538	1.426689034	1.204822395	3.12000175	2.090994304	2.144333516	2.942773048	2.949787298	2.085376325	1.264960349	1.447395634	1.864094564	2.878715966	2.903466276	3.238486034	3.292903061	2.598758552	2.622022662	2.964184501	2.130105244	1.185304903	2.619283097	2.74744511	4.207138317	1.305616311	3.038687482	3.061174631	3.44316057
PC 32:2	0.108081545	0.556561946	0.246212761	0.166031988	0.281091413	0.252018723	0.331057647	0.318256049	0.30793336	0.339445343	0.308380808	0.641883998	0.354525481	0.338460702	0.536961734	0.120332531	0.291139353	0.400522994	0.243860186	0.529207478	0.481627292	0.313916162	0.170985463	0.59270335	0.444529474	0.279478521	0.297526691	0.1480785	0.286894653	0.331427001	0.315290093	0.600121498	0.816263319	0.813163987	0.832822529	0.643877494
PC 33:1	0.556718259	1.102591852	1.061876855	0.649579147	1.020645126	0.93772768	0.959043183	1.341263508	1.119025723	1.167550875	1.144596415	1.061131728	0.865885118	1.018383015	1.417493463	1.329306636	1.161363345	1.112322208	0.802226021	1.143330341	1.071603851	1.159697666	1.309146198	1.439873831	1.27207786	1.262645563	1.167473136	1.102374279	0.875544813	1.086282626	1.149779223	1.114331221	1.316988947	1.192585085	1.197432189	1.304531877
PC 34:0	0.253606957	0.228574279	0.319166124	0.293846239	0.346174546	0.273342969	0.369313012	0.341810461	0.294036343	0.307558778	0.410043661	0.31519293	0.285253285	0.317457947	0.299487406	0.307147663	0.400503591	0.260446038	0.256479169	0.252238507	0.285385208	0.271784836	0.385034388	0.324461302	0.313811938	0.351147672	0.323292355	0.310863149	0.256378062	0.227820446	0.283825267	0.431923853	0.36360001	0.336518478	0.43040955	0.420201977
PC 34:1	10.49447301	25.70576247	15.48711222	15.39745668	15.74391408	15.23707892	15.34095179	16.12280892	13.37624518	14.87683745	16.11502769	13.85024182	14.69191224	16.62614202	19.92534207	18.39369862	16.69190153	26.13078277	14.47831447	18.0096797	17.17486345	16.34101213	19.62026697	18.16162456	14.90249413	17.23081143	18.72793505	16.51426438	15.93694475	17.46674198	12.37982935	22.25479978	19.01729646	13.5575304	11.99520159	13.23335372
PC 34:2	4.276163067	8.293567968	9.182612603	5.309615091	6.978677083	7.503245028	6.110215871	5.043563339	6.900305322	4.158460469	6.561355889	6.140689992	5.691372891	9.508562092	7.698794425	9.988404147	8.061572491	8.134456082	7.783813481	10.29442123	7.40104962	9.068206802	8.456616377	9.723080993	6.952745371	9.155851274	10.02606089	8.416722536	8.928211266	9.060040617	5.821919059	8.873781569	3.130262744	5.154230587	7.405701064	7.303578226
PC 35:0	0.016203134	0.016219541	0.013765935	0.016020115	0.021585629	0.01727282	0.010211882	0.010986612	0.013476763	0.011801453	0.010346288	0.008453118	0.016178676	0.015706072	0.02376096	0.029628182	0.02106324	0.012728173	0.013226133	0.012403999	0.013769735	0.018485072	0.018117027	0.018589241	0.013568926	0.015100097	0.014319509	0.014913618	0.01310936	0.024057061	0.00971947	0.018613076	0.025614919	0.014549903	0.017577791	0.02517914
PC 35:1	0.764856437	0.756134387	1.324273957	1.041445532	1.432239981	1.258544848	0.988046287	1.302429789	1.099750568	1.111915325	0.783837894	1.031045687	1.14479176	1.358476001	1.697588073	1.50026173	1.113359139	1.152143333	1.159245515	1.174574148	0.936343976	1.027132528	1.477643239	1.885871789	1.295070739	1.52884077	1.376156588	1.313010373	0.81679494	1.174865731	0.598869281	1.552753577	1.536296246	1.040041677	1.174582277	1.344043871
PC 36:1	5.816720151	11.42816222	6.109612354	8.400984147	8.88125735	10.81664777	7.826380233	7.475099559	8.040567937	8.587302356	8.364485945	8.160819609	9.698284301	10.36024882	10.00326867	11.68915205	10.78825849	10.32690711	8.291415383	9.13002992	10.80444575	11.69036581	10.20434083	11.39783197	8.981962734	6.704044072	10.01871882	9.457018592	8.76317842	11.52135567	7.814036754	13.06460746	10.25225167	8.05593736	8.302895533	8.032105355
PC 36:4	4.17301694	4.822711104	5.034333891	4.435929509	5.574987519	5.76379157	2.69905826	2.439157951	4.262251562	1.241667571	2.77853251	4.028797644	6.28758146	6.222994882	6.04067181	6.100082801	6.176343513	4.565662253	5.375074719	3.500720297	5.796041103	5.492121652	7.058988696	5.812245088	6.256728676	5.059213651	6.642108676	5.446578712	2.696051572	5.807873785	3.340509185	4.802268494	1.521448348	1.933771914	2.970131835	3.270155937
PC 36:5	0.918581208	1.262681297	1.069186932	1.024550395	1.098253382	1.178522309	0.922622055	1.200180148	0.950859394	0.795935574	0.533455487	0.54374571	1.55337759	1.573080206	1.867162999	0.539107737	1.176945552	1.605565179	0.995284895	1.620516254	1.355047707	1.512932682	1.203223975	1.8025267	1.39532786	1.216520294	1.634666948	1.283324159	1.425723887	1.276819988	0.68515538	1.667110669	0.987920056	0.861675069	0.532240992	0.447244535
PC 38:1	0.074527461	0.061348468	0.078458873	0.100176998	0.067736749	0.093416597	0.021750122	0.048343837	0.06263592	0.037494882	0.045094658	0.030736166	0.057047141	0.071709284	0.102274524	0.06980992	0.072995608	0.034336598	0.146803801	0.039854795	0.129627021	0.116129946	0.056697645	0.073883134	0.061167632	0.053895924	0.06841796	0.051509407	0.060474738	0.099892448	0.054381835	0.063038438	0.025022156	0.027134311	0.03377021	0.024846349
PC 38:2	0.226798138	0.405458288	0.222033492	0.248567981	0.424543336	0.436070073	0.117643442	0.150900752	0.177144961	0.118339083	0.151947341	0.133495572	0.426946135	0.454909107	0.381171598	0.401365423	0.364473951	0.237509501	0.509907818	0.257079679	0.375193828	0.407132261	0.291291335	0.385554399	0.349665349	0.178222697	0.328794771	0.280883158	0.357465428	0.456980876	0.118283073	0.151740781	0.126182761	0.099071559	0.096400074	0.143406082
PC 38:4	5.313208971	8.848013693	5.765183634	5.697184379	6.169324562	6.679253449	4.852055274	4.195931772	3.769309875	3.74521032	4.245803249	3.651679593	6.882423443	6.908912624	6.922085507	6.765223703	7.100853014	8.634413676	6.485030069	6.196763403	6.251818161	6.240479598	6.334407846	5.705905002	7.06543072	4.679281175	6.760827814	6.015379623	6.83228535	5.870655314	3.298828608	4.963656758	3.813477113	2.653426582	3.04476743	3.019473341
PC 38:5	0.915746311	1.305122459	1.17062075	1.287880561	2.407366847	2.913350845	1.015262493	1.541929486	2.20619416	0.754259213	0.557535264	1.88720392	2.156026775	2.539366921	2.483374399	2.266307574	2.851374933	0.894696733	2.885990201	1.594794272	3.191679848	2.643368962	2.858621631	2.668032127	1.924115206	2.363497423	2.421467375	1.701031392	1.407423285	3.117888691	1.084434841	2.243792707	1.363935502	1.14521831	1.863983722	1.836123033
PC 38:6	2.225671568	5.890010647	2.745801984	2.039168394	3.755302996	5.144948231	2.338269614	1.950609333	1.923620952	1.033643268	1.387347435	2.011253548	2.532361596	4.779042251	3.908785266	3.124263362	5.528683256	5.797671227	4.730054277	3.012266594	4.13140779	1.642066807	6.279883782	3.783024009	4.587365324	5.666273008	5.026793127	5.057101595	4.887884312	4.557091057	1.687061804	2.67090133	1.073882529	0.635390665	0.566267275	0.590229189
PC 38:7	0.198543588	0.568988951	0.274594057	0.197001693	0.239154895	0.220834366	0.27569789	0.391609755	0.258366707	0.247433887	0.083652665	0.294695106	0.509976502	0.541099697	0.509027225	0.167754223	0.262287837	0.361733086	0.478236809	0.420946049	0.484354898	0.442952136	0.475507624	0.600815342	0.628022111	0.286279611	0.417369324	0.322713843	0.360049029	0.636803724	0.32838953	0.483743359	0.277590197	0.211009802	0.411023428	0.292874727
PC 40:2	0.006707317	0.003404168	0.009763342	0.011555868	0.008708163	0.015114237	0.005076317	0.008837798	0.015701099	0.004767803	0.012685866	0.013414042	0.007191067	0.011316001	0.008847308	0.012488724	0.01156597	0.003780175	0.017757728	0.009011734	0.014091077	0.014661683	0.011181714	0.015292966	0.00727112	0.013853907	0.006947993	0.009002317	0.009587108	0.018544422	0.01174319	0.016525869	0.005308864	0.008942627	0.012939322	0.013990338
PC 40:4	0.078502955	0.159958062	0.095537786	0.129898837	0.130804598	0.150925644	0.102212645	0.113135975	0.112334577	0.091676406	0.109059775	0.089257066	0.085768348	0.127446287	0.133922796	0.14546933	0.109113652	0.10283898	0.134176878	0.108315471	0.159717922	0.155424049	0.140965308	0.168976359	0.108932928	0.12109848	0.1271459	0.113088898	0.104045714	0.152940513	0.086654361	0.136289253	0.091012063	0.086459299	0.078140939	0.082013479
PC 40:6	2.748035503	2.836265113	2.88653296	2.63216371	2.637798789	3.096647889	2.544516232	2.111471036	1.789435623	1.75091758	2.025645284	1.689890262	3.410252434	3.22177929	3.550642153	3.757376864	3.884819325	4.835422224	2.755861242	3.364797509	2.737469159	3.093806279	3.536817689	2.779261423	4.29989287	3.000214313	3.283634646	3.215455276	3.529058518	2.918443958	1.501599375	2.262139023	1.567286752	1.074775097	1.329044322	1.218009949
PC 40:7	0.160724089	0.704271567	0.341647634	0.225322143	0.373365054	1.511867038	0.282123596	0.269176532	0.774542006	0.137364497	0.029205639	0.420856744	1.097914301	0.608004954	0.25607592	0.718923684	1.19753084	0.127498519	1.022766954	0.225422196	1.735823499	0.614014403	1.38399552	1.299967872	1.040031381	1.020171974	1.185518005	0.318837738	0.182355481	1.446912865	0.230653601	0.127678648	0.099345638	0.171133266	0.78318904	0.202456539
PC 40:8	0.038596963	0.457059994	0.061330734	0.057333512	0.065493676	0.095232638	0.083393045	0.077603267	0.033160779	0.070491113	0.061808821	0.020087789	0.138135967	0.131417303	0.071834461	0.187260511	0.095398368	0.364030841	0.111906353	0.121311079	0.179031798	0.089250098	0.025424701	0.276926566	0.068653405	0.097947855	0.198578308	0.03530548	0.188493562	0.214302451	0.041583132	0.068797364	0.066821007	0.027181593	0.025323348	0.016921521
PC 40:9	0.007656488	0.006893937	0.01774288	0.027177596	0.020280267	0.028624805	0.007251619	0.016886524	0.023762618	0.013016426	0.003788396	0.00901868	0.014930092	0.021885253	0.034181807	0.036491916	0.03579839	0.001672943	0.02408886	0.013871979	0.021552086	0.027760118	0.03394222	0.032666862	0.023431268	0.035655496	0.024813748	0.032723939	0.011047579	0.027724369	0.010694235	0.014535127	0.006863791	0.009955168	0.020640681	0.022910591
PC 42:7	0.023444846	0.069183707	0.049169345	0.051449871	0.054419194	0.078882059	0.018808518	0.025330916	0.024410495	0.022558754	0.01693795	0.019334959	0.051181474	0.057395273	0.038132056	0.051530517	0.057563123	0.048292507	0.082187358	0.043511359	0.06135274	0.055093797	0.057427949	0.052816147	0.047833848	0.042726293	0.052880405	0.042708806	0.064212276	0.071584636	0.014783982	0.015497111	0.014217526	0.011902461	0.017226375	0.018082566
PC 42:8	0.002497011	0.005961091	0.007527166	0.00422109	0.006365063	0.011115322	0.002761145	0.006439295	0.006319793	0.001844524	0.002139618	0.005082712	0.006715867	0.007057444	0.007345975	0.010107654	0.008794239	0.003829655	0.009058297	0.00564635	0.019951222	0.01082606	0.010756616	0.013844864	0.007317415	0.007837018	0.008569064	0.010407014	0.004915541	0.011980424	0.002904896	0.005437992	0.00554094	0.003265044	0.004803842	0.0058973
PC 42:10	0.025727692	0.112496033	0.030735185	0.039951495	0.033307496	0.055669562	0.054363716	0.034901928	0.040809393	0.034073215	0.018686596	0.0232632	0.056504508	0.069872132	0.073551888	0.072695943	0.096402176	0.058253254	0.057653855	0.046021446	0.065661362	0.07492659	0.153338876	0.064515377	0.038857403	0.057220719	0.173926866	0.052178552	0.06405032	0.197587088	0.023760215	0.032198755	0.029823224	0.019390556	0.046637397	0.028975463
ChE 16:0	0.008970045	0.00566399	0.003276651	0.003984686	0.006439116	0.002634582	0.01107326	0.009992127	0.0055622	0.004715107	0.004897925	0.003591299	0.003969186	0.007671045	0.004526108	0.010745284	0.007782614	0.001677697	0.001884042	0.003239626	3.28768E-05	0.006721979	0.003991385	0.003347323	0.005901186	0.002643016	0.007356129	0.001388007	0.006167723	0.005923592	0.00018496	0.002781202	0.001350188	0.005457888	0.004543347	0.004943526
ChE 16:1	0.413370176	0.785778381	0.363563353	0.312907951	0.446342134	0.136489902	2.039241035	1.146305361	0.885202731	1.512215664	1.467818219	0.957626656	0.238686797	0.469452552	0.426748554	0.27580314	0.40042585	0.112881257	0.177094905	0.403260022	0.002482578	0.356449733	0.308261961	0.207654268	0.156721503	0.379377025	0.468234616	0.077309699	0.343280044	0.437626217	0.771968322	0.970944596	3.681703607	1.540917856	0.93725239	0.870123767
ChE 18:1	0.876018765	1.880909424	0.647605801	0.602861203	0.607504808	0.301747476	2.631933323	1.511467885	1.056404528	1.746760132	1.618772898	1.096424605	0.54216987	1.015763785	0.967237418	0.668098835	1.045306473	0.428187799	0.334361026	0.759528304	0.004682465	0.675305835	0.633663454	0.446047511	0.247291885	0.871397647	1.2342752	0.156621964	0.808228634	0.854344042	1.004812227	1.182108148	4.920932704	1.711438357	1.041265684	1.09878436
ChE 18:2	0.436467373	0.594729177	0.456809273	0.279988882	0.37286469	0.111963848	2.127643209	1.377531187	0.92064872	1.360732708	1.401927263	0.821699172	0.22606084	0.490901799	0.507083289	0.310317667	0.671569501	0.162281464	0.131510552	0.387247547	0.002075151	0.312263731	0.341764658	0.222064406	0.197447601	0.563724922	0.560603863	0.087584863	0.321471757	0.400003013	0.900743166	0.879943125	3.098163017	1.424232154	0.938666298	0.98146342
ChE 18:3	0.044314355	0.108688535	0.05424288	0.034928275	0.045385728	0.013992152	0.313072082	0.230030299	0.141212103	0.201683057	0.229674647	0.124715203	0.027157183	0.050327014	0.066978016	0.036779032	0.081415779	0.035066118	0.013979446	0.044430374	0.00025119	0.036837882	0.042071991	0.028243991	0.007920061	0.087578558	0.070604813	0.010827248	0.039456092	0.05066792	0.185265607	0.148867115	0.467859476	0.2607495	0.162490547	0.189513042
ChE 20:1	0.00077399	0.00059067	0.000400979	0.000315221	0.000299086	0.00012847	0.001287566	0.000686945	0.000498563	0.000456307	0.000630351	0.00037223	0.000275051	0.000848487	0.00039905	0.000602107	0.00049198	4.50411E-05	0.000226923	0.000287177	2.23745E-06	0.000351083	0.000253104	0.000237663	0.000162113	0.000623972	0.000607679	8.87028E-05	0.000497594	0.000476494	0.000567895	0.000335635	0.001423355	0.00052843	0.000302129	0.0005355
ChE 20:2	0.003232166	0.004880417	0.000930178	0.001812245	0.001238308	0.000664129	0.015697125	0.003231017	0.002929589	0.0018087	0.004301797	0.005939134	0.001917188	0.002408732	0.003264469	0.001898121	0.002384658	0.001069584	0.001122996	0.001617236	1.16492E-05	0.001615256	0.002199643	0.001196835	0.000626984	0.001343649	0.002869913	0.000399836	0.002416096	0.001818916	0.00438666	0.005042619	0.023414199	0.005028092	0.004705474	0.004936763
ChE 20:3	0.016694399	0.015222693	0.016382758	0.008416056	0.014599932	0.005035126	0.18433234	0.101180132	0.083850011	0.114201633	0.1288714	0.078982693	0.010652437	0.023420833	0.015548757	0.014958276	0.025222045	0.00512115	0.006431184	0.008910332	6.86416E-05	0.013533152	0.008676551	0.007709045	0.007727076	0.022443455	0.027226489	0.002616023	0.014950665	0.01463128	0.087579613	0.070364918	0.228967221	0.115031146	0.076639098	0.095725045
ChE 20:4	0.144762304	0.200293695	0.131083158	0.115109075	0.108007615	0.039930557	0.599576034	0.45114554	0.292876874	0.437942599	0.451416836	0.238331571	0.077653293	0.153102246	0.140619108	0.096296255	0.21871686	0.078418309	0.050119584	0.098425536	0.000586527	0.084415435	0.092863204	0.064463455	0.016355904	0.258918874	0.226135269	0.024461019	0.098512708	0.111589538	0.346260585	0.237476698	0.79940128	0.410025041	0.290270396	0.346168225
ChE 20:5	0.011499001	0.016915798	0.010166764	0.009278205	0.010034456	0.003965426	0.088637114	0.052953888	0.047398356	0.086422121	0.090441421	0.050458218	0.00677195	0.016083056	0.019178453	0.010445003	0.02256439	0.010244974	0.004229422	0.012547623	6.90247E-05	0.005827493	0.01032726	0.007346795	0.001948986	0.026304159	0.021847607	0.002754012	0.009868586	0.011411922	0.062187409	0.053314581	0.128154301	0.10931289	0.072462202	0.05132017
ChE 22:3	0.00202193	0.008397388	0.00183121	0.001703131	0.001826336	0.000834222	0.008473073	0.005325234	0.0040445	0.007840377	0.006646361	0.004689788	0.001422745	0.00275086	0.002101662	0.001681372	0.002292457	0.002618272	0.001021764	0.001676354	1.14054E-05	0.001615943	0.001229357	0.000878956	0.000669523	0.002799174	0.002564284	0.000332376	0.001693056	0.002028057	0.005000118	0.004299009	0.022689259	0.005945843	0.003515896	0.004180648
ChE 22:4	0.000863592	0.002515606	0.001062445	0.000729552	0.000994883	0.000304779	0.040463965	0.022747995	0.014713147	0.020186536	0.026328464	0.013728736	0.000454296	0.000963179	0.000836335	0.000580098	0.001250442	0.000827256	0.000340091	0.000658372	4.10967E-06	0.000600151	0.000534442	0.000363466	0.000483445	0.009498803	0.001077926	0.000162075	0.000726078	0.000781043	0.025004459	0.019414513	0.047403428	0.025333844	0.017201296	0.020735094
ChE 22:5	0.001089823	0.00125537	0.000974344	0.000769965	0.001006233	0.000293672	0.018588054	0.010708279	0.00772186	0.009310797	0.013212327	0.007871169	0.000465264	0.000848054	0.000972303	0.000702027	0.001146028	0.000264138	0.000309829	0.000908037	3.88354E-06	0.000760105	0.001369428	0.000451164	0.0002752	0.006315007	0.001263685	0.000206766	0.0006357	0.00072383	0.012003368	0.010507188	0.016564435	0.014226183	0.010454479	0.010903593
ChE 22:6	0.2032362	0.260624892	0.240297836	0.185567695	0.18201963	0.070020546	0.585824596	0.678606899	0.33232742	0.44204813	0.463644963	0.227790798	0.113086549	0.198956093	0.205814309	0.131591567	0.234774191	0.116203189	0.070005306	0.192697351	0.000745566	0.116235562	0.193195973	0.087356411	0.037116212	0.356904173	0.277605754	0.046785368	0.125309819	0.176679461	0.311583833	0.218528806	0.71237195	0.377323731	0.279966146	0.337009874
DG 32:0	0.139862856	0.172343898	0.231101029	0.194417303	0.221218136	0.153227985	0.339494947	0.210970794	0.205247241	0.275854602	0.292229806	0.271334346	0.133110078	0.11414971	0.16676206	0.191336041	0.144047971	0.186774085	0.210504838	0.147765995	0.125235523	0.212726932	0.19662546	0.211474881	0.180295082	0.153316609	0.167096696	0.13527104	0.133694788	0.212510361	0.313062268	0.254121258	0.28308572	0.206408807	0.261997949	0.287444247
DG 32:1	0.838316948	1.230886625	1.606329068	1.142847446	1.843061147	1.153769425	2.007079401	1.194154958	1.171121662	2.035447528	1.720400396	1.645879673	0.807706833	0.776590995	1.109147733	1.2188724	0.721064851	0.89755735	1.611365458	1.090608656	1.047446847	1.516314849	1.277184209	1.548914833	1.171684623	0.748656364	1.205822555	0.744973438	0.947535383	1.488423656	2.058212399	1.667500983	2.496746767	1.634670606	1.874113632	1.840895309
DG 32:2	0.164156829	0.276970435	0.288989512	0.199299714	0.405565025	0.250628169	0.52074126	0.235387269	0.27541493	0.539137545	0.439653066	0.377134291	0.154765028	0.194505485	0.288414321	0.227693302	0.11715616	0.181039463	0.340473763	0.33257119	0.316999102	0.37033969	0.280185299	0.339252251	0.253203436	0.107200581	0.243604305	0.142041918	0.23596425	0.270588201	0.501686642	0.378209695	0.777389225	0.529932051	0.582468911	0.462122933
DG 34:2	1.77408718	2.42301468	3.096525101	2.098519532	3.511932624	2.89104824	6.087075031	2.41701745	3.497763028	5.492757634	4.075762934	5.500824166	1.916667268	2.140503266	2.253113797	2.207021949	1.562419219	1.70377423	4.324659825	2.676371863	2.639479534	3.110622208	2.928240764	3.403102057	2.250184903	1.381924978	2.429200112	1.669069085	2.42449331	3.001471802	6.184111408	4.641444436	6.229771978	5.554105199	6.667910607	5.400010184
DG 36:1	0.335855485	0.266405304	0.725401567	0.387255871	0.554374705	0.502396848	0.573741745	0.50455757	0.536489793	0.513219707	0.550411878	0.607501889	0.307635558	0.378667239	0.409782038	0.545156458	0.716948992	0.340841303	0.526247026	0.383538407	0.350960843	0.526334556	0.61235321	0.639059522	0.426302916	0.43990427	0.421284337	0.50517377	0.38582919	0.613655888	0.653505153	0.403374843	0.317575299	0.487582398	0.665855527	0.585260183
DG 36:2	4.145479546	5.209707834	7.440719459	4.439998815	6.444999477	7.032004437	8.567480458	5.743937291	6.25704405	8.241706109	7.605945522	8.486796354	5.341872511	6.464549796	6.234322105	5.316599927	5.935083477	5.257853426	8.678964764	6.72596996	6.206057337	7.371534931	8.23343133	8.853527178	4.869804667	3.358512353	5.279740494	5.687474419	6.403055614	7.360999741	8.833060995	6.423537302	7.177733188	6.858755967	9.027108207	7.782650056
DG 36:3	0.705718023	0.562041932	1.400027596	0.645643784	1.097207023	0.939033997	1.466189154	0.818953739	0.816086584	1.24068811	1.329205096	1.23166425	0.567197457	0.779739324	0.848850778	0.803476449	0.826352492	0.756555701	1.089082842	1.104455986	0.926322466	1.013719408	1.310459133	1.24101919	0.814469353	0.609197211	0.914386604	0.777216283	0.848421804	0.907840593	1.400227369	0.831967963	1.052264452	1.164100202	1.470862301	1.26148543
DG 36:4	0.168522541	0.215017037	0.357083165	0.241894203	0.333182584	0.271532031	0.305196335	0.209281038	0.208378263	0.240685384	0.238029021	0.308272345	0.195618129	0.1732312	0.198288588	0.31896003	0.22378766	0.240224987	0.300262045	0.204709245	0.19183854	0.272109793	0.220969624	0.252661074	0.237537651	0.286680366	0.290090884	0.167580111	0.157903265	0.276169934	0.25128473	0.237984354	0.182986954	0.202481424	0.295779242	0.318916537
DG 36:5	0.016020871	0.029843995	0.034758689	0.030681575	0.038470743	0.036661859	0.050855045	0.03357525	0.038992837	0.055743735	0.039823358	0.050999925	0.022064267	0.022732385	0.033759884	0.03461423	0.021768624	0.03084587	0.039372321	0.037717232	0.035472949	0.04318013	0.03519732	0.039015106	0.030721961	0.022204637	0.032996692	0.022184624	0.018949768	0.030867496	0.041593595	0.031187286	0.057855933	0.051559392	0.091339095	0.074352111
DG 38:2	0.209519667	0.172881006	0.46933284	0.24277479	0.340804038	0.313495118	0.202842042	0.239019039	0.24054127	0.194074834	0.218595482	0.251352746	0.180664635	0.285076976	0.221165177	0.253456611	0.357912613	0.171571655	0.466785049	0.231924179	0.240690596	0.283719183	0.371144954	0.421693997	0.219421278	0.180675673	0.233802371	0.287637747	0.284519046	0.361738953	0.31521597	0.11614055	0.117355818	0.169686935	0.17595854	0.236814635
DG 38:4	0.499024186	0.479836504	0.817173239	0.604268452	0.756489331	0.679256647	0.66001149	0.335827211	0.497226497	0.350918277	0.640929966	0.655825036	0.605596092	0.691502682	0.71190506	0.700859278	0.757852443	0.730297762	0.732274976	0.635809639	0.600006918	0.755631336	0.688803919	0.746202552	0.66987477	0.681479524	0.642066897	0.933648855	0.67177307	0.618344626	0.581681883	0.537818855	0.30611452	0.367205789	0.403147177	0.449155056
DG 38:5	0.113987025	0.17420836	0.298835381	0.187189254	0.291241116	0.242778528	0.28480645	0.192437241	0.264009042	0.390827198	0.274109188	0.331587398	0.129654174	0.15855014	0.160384113	0.219108065	0.163406837	0.161524987	0.28472691	0.192099321	0.197445807	0.242767547	0.221146796	0.241348117	0.18144638	0.227513889	0.209073074	0.162077168	0.136114258	0.220312679	0.295836294	0.256992938	0.313301607	0.272893525	0.505186496	0.525644588
DG 38:6	0.359827202	0.55044208	0.543711297	0.420131206	0.661474768	0.472801447	0.451451287	0.266322718	0.203994416	0.176702225	0.259925069	0.282857549	0.355943985	0.331884931	0.326225946	0.450040403	0.376945226	0.303517241	0.636925509	0.260930654	0.212330473	0.32931394	0.222035733	0.210254463	0.435456945	0.50827123	0.490618846	0.224118458	0.271157555	0.40644689	0.217190167	0.13088987	0.133073985	0.131107112	0.150522825	0.140334583
DG 38:7	0.018918191	0.043756324	0.04237747	0.025781589	0.03963146	0.043300021	0.032924327	0.018478254	0.036616775	0.031322908	0.035319376	0.02264647	0.032792069	0.036806883	0.037442913	0.033651489	0.0169687	0.023673841	0.058694293	0.040317114	0.017455239	0.029183248	0.019600216	0.021747377	0.036952419	0.024572039	0.041748937	0.013649615	0.024329265	0.020281699	0.017811403	0.01097233	0.010038745	0.01643742	0.032104526	0.032497752
DG 40:4	0.006764911	0.005371537	0.026496395	0.007994306	0.015062409	0.012146019	0.016386933	0.012858544	0.013590476	0.013997298	0.019202525	0.025972318	0.005728564	0.009923039	0.008444434	0.00946524	0.015037283	0.010980626	0.014128581	0.011367631	0.009729228	0.011031103	0.019762782	0.017349152	0.009322476	0.009379039	0.009917756	0.010058936	0.008802544	0.011927758	0.019761271	0.008285012	0.007409559	0.011198422	0.01609749	0.017781071
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name	m/z
PC 32:0	734.5704
PC 32:1	732.5546
PC 32:2	730.5356
PC 33:1	746.5685
PC 34:0	762.6011
PC 34:1	760.586
PC 34:2	758.5704
PC 35:0	776.616272
PC 35:1	774.5999
PC 36:1	788.6172
PC 36:4	782.5701
PC 36:5	780.550842
PC 38:1	816.6466
PC 38:2	814.6334
PC 38:4	812.606812
PC 38:5	808.5853
PC 38:6	806.5699
PC 38:7	804.5544
PC 40:2	842.6628
PC 40:4	838.629395
PC 40:6	834.6016
PC 40:7	832.5853
PC 40:8	830.5697
PC 40:9	828.551
PC 42:7	863.625183
PC 42:8	858.5988
PC 42:10	855.569519
ChE 16:0	642.618286
ChE 16:1	640.602417
ChE 18:1	668.633179
ChE 18:2	667.621094
ChE 18:3	664.601868
ChE 20:1	696.664429
ChE 20:2	694.647461
ChE 20:3	692.633667
ChE 20:4	690.617676
ChE 20:5	688.600952
ChE 22:3	720.663879
ChE 22:4	718.648499
ChE 22:5	716.633057
ChE 22:6	714.617615
DG 32:0	586.539673
DG 32:1	584.52356
DG 32:2	582.507629
DG 34:2	610.539246
DG 36:1	640.587158
DG 36:2	638.571228
DG 36:3	636.55481
DG 36:4	634.539185
DG 36:5	632.523132
DG 38:2	666.602234
DG 38:4	662.570862
DG 38:5	691.65802
DG 38:6	658.53894
DG 38:7	656.523315
DG 40:4	690.602539
METABOLITES_END
#END