m/z_RT Plasma 1 Plasma 2 Plasma 3 Plasma 4 Plasma 5 Plasma 6 Plasma 7 Plasma 8 Plasma 9 Plasma 10 Serum 1 Serum 2 Serum 3 Serum 4 Serum 5 Serum 6 Serum 7 Serum 8 Serum 9 Serum 10 Time point 1 - plasma_1 Time point 1 - plasma_2 Time point 1 - plasma_3 Time point 1 - serum_1 Time point 1 - serum_2 Time point 1 - serum_3 Time point 1 - blood_1 Time point 1 - blood_2 Time point 1 - blood_3 Time point 1 - DBS venous_1 Time point 1 - DBS venous_2 Time point 1 - DBS venous_3 Time point 1 - DBS finger_1 Time point 1 - DBS finger_2 Time point 1 - DBS finger_3 Time point 2 - plasma_1 Time point 2 - plasma_2 Time point 2 - plasma_3 Time point 2 - serum_1 Time point 2 - serum_2 Time point 2 - serum_3 Time point 2 - blood_1 Time point 2 - blood_2 Time point 2 - blood_3 Time point 2 - DBS venous_1 Time point 2 - DBS venous_2 Time point 2 - DBS venous_3 Time point 2 - DBS finger_1 Time point 2 - DBS finger_2 Time point 2 - DBS finger_3 Time point 3 - plasma_1 Time point 3 - plasma_2 Time point 3 - plasma_3 Time point 3 - serum_1 Time point 3 - serum_2 Time point 3 - serum_3 Time point 3 - blood_1 Time point 3 - blood_2 Time point 3 - blood_3 Time point 3 - DBS venous_1 Time point 3 - DBS venous_2 Time point 3 - DBS venous_3 Time point 3 - DBS finger_1 Time point 3 - DBS finger_2 Time point 3 - DBS finger_3 524.4_12.27 20900000 19510000 22530000 21190000 25300000 22620000 23420000 21120000 23300000 19200000 37120000 37840000 39810000 39950000 39220000 39220000 33540000 37680000 35420000 17750000 468.3_5.03 417300 391500 437800 413600 527700 462300 468500 463800 448000 363800 803300 862600 831400 883400 893500 808400 733000 980100 786300 375300 544.3_7.10 3371000 3123000 3414000 3282000 3938000 3600000 3782000 4140000 3926000 3079000 5067000 4880000 4946000 5166000 5342000 4954000 4311000 5397000 4523000 2502000 522.4_9.26 10160000 9413000 10090000 9094000 11430000 10420000 10920000 11290000 12010000 9029000 13340000 13860000 14080000 14580000 15050000 13330000 11880000 15280000 13080000 6740000 536.5_31.99 10670 13180 16210 12740 18400 12990 13150 14560 17930 12390 13950 14840 16340 15760 14670 17690 20870 15300 16870 8127 480.3_12.69 2500000 2414000 2771000 2563000 3091000 2670000 2889000 2623000 2808000 2376000 4426000 4770000 4743000 4870000 4900000 4602000 4108000 4297000 4317000 2211000 452.3_8.62 1962000 1806000 1988000 1976000 2288000 2051000 2221000 2031000 2127000 1786000 2946000 3016000 3159000 3152000 3223000 3028000 2733000 2904000 2894000 1503000 500.3_7.42 1505000 1396000 1492000 1390000 1813000 1600000 1654000 1798000 1725000 1401000 1667000 1743000 1729000 1789000 1825000 1622000 1431000 1731000 1583000 861800 732.6_29.66 7139000 7213000 8019000 7701000 9170000 7397000 8036000 7906000 8477000 6987000 7650000 7152000 7926000 7878000 8158000 8120000 6448000 7588000 7021000 3381000 760.6_32.44 71840000 80250000 68850000 68000000 85690000 68180000 72900000 82240000 81180000 64570000 74210000 83910000 84980000 89250000 76860000 92220000 70430000 80700000 69470000 39020000 810.6_33.53 27310000 26630000 28110000 28070000 27750000 28010000 28820000 30540000 30840000 26190000 27160000 31970000 30300000 33950000 37180000 33640000 30390000 30670000 30340000 16480000 716.5_32.92 997700 889700 987400 965500 1112000 1012000 1078000 1091000 1062000 896800 1339000 1468000 1508000 1531000 1615000 1432000 1311000 1315000 1328000 657000 762.5_30.16 37050 31180 29620 29760 36560 34270 40200 49670 38210 33080 50440 54460 66460 52280 57500 55890 41800 59230 52910 25620 747.5_30.55 65970 67210 66500 59360 82980 71830 70270 64470 73150 57030 82360 82020 80330 91320 97860 82210 74730 77840 83370 47040 835.5_29.87 165900 156800 175200 174300 199900 181800 193800 191700 197800 153800 214700 212800 216500 219500 200600 205200 203600 204700 195900 103000 885.6_31.06 1391000 1365000 1435000 1449000 1763000 1552000 1732000 1880000 1745000 1451000 1761000 1793000 1943000 2028000 1991000 1859000 1664000 1810000 1797000 925100 857.5_28.29 205300 192400 209000 214900 272200 209900 253900 266200 256400 210400 258600 287600 284000 290600 294900 265800 256300 274700 261400 135500 731.6_31.50 22340000 22750000 23860000 24350000 25900000 23260000 24640000 22280000 25400000 21070000 27010000 29480000 29060000 31240000 30740000 29920000 26520000 27060000 27110000 14200000 815.7_38.85 12820000 13500000 13910000 13990000 15560000 13620000 14140000 13420000 13600000 12510000 16340000 17130000 17900000 18550000 19140000 17740000 17280000 16480000 18050000 8600000 536.5_32.00 13840 15760 15140 20720 24300 82190 57910 70640 18960 14900 15930 13610 23690 12030 6668 9332 10640 20590 20000 24400 27610 32340 29780 13570 11350 13450 19980 21060 18350 8150 12510 5952 12700 11610 15590 75670 63420 69200 17290 13910 20610 26370 18950 18870 468.3_5.03 1113000 843000 1002000 849000 1075000 1198000 909300 778300 813900 240400 241200 224700 206300 227300 159400 336500 366800 349000 557100 636100 625900 8176 2263 2396 109500 112300 118800 128000 133800 117100 493400 394000 393900 533000 534000 535100 443400 354600 414900 132900 138000 152900 135400 131100 127100 522.4_9.25 13420000 10090000 12350000 10120000 13500000 14460000 9572000 8775000 9182000 3052000 3217000 2665000 2861000 2701000 1885000 6834000 7509000 7166000 11180000 13090000 13310000 82210 68080 75750 2438000 2393000 2556000 2639000 2695000 2599000 8890000 7337000 6869000 9600000 9924000 10120000 7638000 6817000 6980000 2461000 2881000 2906000 2432000 2526000 2477000 544.3_7.09 4230000 3270000 4086000 3117000 4155000 4698000 1403000 1473000 1261000 778000 863000 781000 727100 770700 518000 1709000 1725000 1689000 2530000 3068000 3177000 8683 9358 7768 478300 515000 496200 536100 539600 490000 2213000 2016000 1767000 2495000 2550000 2618000 1516000 1258000 1319000 514400 618100 613100 515300 537200 522700 480.3_12.68 3223000 1962000 3003000 2165000 2968000 3459000 3552000 3215000 3312000 1313000 1303000 1191000 1181000 1231000 826300 1100000 1229000 1131000 1847000 2109000 2134000 76060 65240 70210 830800 911100 894000 941300 902400 1010000 1923000 1721000 1516000 2112000 2288000 2233000 2745000 2485000 2570000 1060000 1260000 1348000 1048000 1231000 1158000 452.3_8.61 3058000 2021000 2903000 2009000 3019000 3282000 3409000 2901000 3052000 1056000 1076000 1007000 1033000 965100 686700 929300 1027000 951300 1566000 1729000 1818000 48750 61680 59650 561300 584600 594400 681500 673900 689400 1841000 1562000 1422000 2038000 2128000 2072000 2050000 1939000 2021000 749800 878900 936700 795900 860900 881800 500.3_7.42 3088000 2075000 3054000 2047000 3049000 3511000 865600 1009000 712600 707100 734500 742200 721600 698500 491500 903700 1040000 992300 1617000 1940000 1993000 14400 15790 13840 414000 433100 463000 542800 518800 528100 1492000 1228000 1151000 1635000 1744000 1653000 938400 798300 838600 459000 538900 522800 549100 608600 650100 760.6_32.41 105700000 75770000 85220000 82340000 98160000 94890000 116900000 96270000 102800000 33360000 33720000 38480000 37170000 34060000 26420000 51400000 59270000 53940000 72930000 97210000 93490000 4074000 4519000 4256000 29220000 31660000 29910000 32710000 36840000 39120000 57280000 47610000 45570000 67880000 66100000 70950000 96630000 84510000 82710000 26470000 38230000 35590000 30980000 37810000 30940000 732.6_29.63 10770000 8851000 9639000 8091000 10510000 10480000 9294000 8621000 8754000 3069000 3153000 3026000 2762000 3046000 1796000 4016000 4149000 4017000 7040000 8464000 8466000 262900 269100 246900 2105000 2012000 2479000 2141000 2388000 2482000 4837000 4422000 4424000 5867000 6119000 6187000 6746000 6450000 6258000 2359000 2406000 2569000 2148000 2531000 2108000 810.6_33.50 37490000 26580000 31400000 27590000 34620000 38040000 11770000 16820000 12200000 7388000 7851000 6865000 6616000 7647000 4579000 18780000 18150000 17210000 28480000 36680000 31820000 541500 448400 642300 5884000 5520000 6064000 4973000 7333000 6518000 19160000 17050000 15050000 22390000 25100000 22060000 18340000 16750000 18860000 6098000 6697000 6403000 6552000 6374000 5758000 716.5_32.89 1606000 972000 1489000 1001000 1458000 1578000 65060000 58000000 58730000 19830000 20280000 18230000 17970000 20720000 11450000 650000 767800 724900 1150000 1376000 1385000 10300000 10710000 10830000 16890000 18130000 19300000 19400000 20450000 21950000 723000 623600 568600 828900 869000 787300 59170000 57120000 57190000 16160000 19530000 20930000 18410000 19930000 17320000 762.5_33.96 4534000 2696000 4295000 2936000 4490000 5058000 7315000 10640000 8920000 5970000 6034000 5526000 5272000 6298000 3408000 1574000 1805000 1755000 2739000 3260000 3206000 1794000 1752000 1966000 4930000 4922000 5383000 5537000 6125000 6408000 2340000 1949000 1813000 2749000 3043000 2754000 15590000 15000000 15640000 4622000 5322000 5609000 5443000 5649000 4927000 747.5_30.52 140300 96930 123000 96300 136900 137300 283100 267800 245500 96450 106200 92300 73740 113100 57890 39460 41890 41140 62720 82590 83540 52070 41290 43390 83460 74620 95400 77960 86610 98030 69810 68270 61750 93850 102300 94760 252600 242300 265700 94140 120300 119200 90380 119100 84930 835.5_29.84 230100 185700 231400 173900 241600 254800 264800 243600 227400 32640 40920 41690 44140 51710 29480 176700 187300 170100 252100 333000 306900 5342 7918 6389 54430 52080 54380 52320 52790 59660 114300 107100 105900 124400 142900 127200 171400 195800 206800 35580 51380 54270 50580 56500 36010 885.6_31.04 2200000 1529000 2231000 1637000 2235000 2325000 1032000 1372000 1153000 318000 333100 337100 283700 433000 205700 801100 978700 882300 1519000 1712000 1676000 37690 39100 45790 305400 318800 334100 298500 342500 378800 1055000 925200 913300 1201000 1354000 1224000 1460000 1615000 1703000 365300 409400 449500 347300 386800 319900 857.5_28.26 297900 204200 277400 234700 307400 316100 139800 200900 160800 48700 52230 46790 41080 61140 33350 84210 99830 99840 162900 174500 192600 4543 3869 5404 36910 38730 44330 43600 45930 45080 116600 99370 96160 144900 140300 132500 171100 172700 217400 37780 50170 60670 43250 54610 39010 731.6_31.49 37760000 27290000 37500000 28900000 36870000 40950000 50750000 43760000 45390000 11680000 12710000 11120000 10630000 12010000 7869000 16120000 19760000 18220000 28040000 33250000 33370000 1022000 1212000 1259000 10580000 11740000 11490000 12370000 12820000 13430000 20320000 18220000 16910000 22150000 25110000 24080000 38620000 36300000 38650000 9492000 12870000 11960000 11020000 12420000 11440000 815.7_38.82 18980000 13410000 18160000 13540000 17720000 21460000 83480000 71670000 73590000 17940000 17350000 16060000 14550000 18790000 10270000 8430000 9254000 8766000 14240000 17230000 17040000 2738000 3650000 3519000 14770000 15230000 15930000 16050000 16350000 17370000 9357000 7789000 7751000 10140000 11190000 10870000 54660000 54870000 54280000 12510000 15630000 16140000 14280000 16260000 13700000