Upload and Manage Experimental Data and Metadata

The Metabolomics Consortium Data Repository and Coordinating Center (DRCC) is now accepting metabolomics data for small and large studies on cells, tissues and organisms via the Metabolomics Workbench. We can accommodate a variety of metabolite analyses, including, but not limited to MS and NMR. In order to ensure reproducibility and interoperable use of data, we require experimental metadata (see tutorials) to be deposited along with the metabolite measurements. Processed data (measurements) maybe in the form of quantitated metabolite concentrations, MS peak height/area values, LC retention times, NMR binned areas, etc. Raw data in the form of MS and NMR binary files and associated parameter files may also be uploaded. We accept data from both targeted and untargeted studies. The Metabolomics Workbench also provides a suite of tools for analysis and visualization of the data. Step-by-step instructions for the whole process are provided below.

Requirements for depositing data via the Metabolomics Workbench:

  1. Register.
  2. E-mail us for authorization (help@metabolomicsworkbench.org).
    • Please wait for us to tell you that you have been authorized (usually w/in 24hrs).
  3. Log in.
  4. The use of the common metabolite names in the RefMet database is strongly encouraged in order to be able to compare and contrast metabolite data across different experiments and studies. For your convenience an online tool is available to map your current metabolite identifications (where possible) to the corresponding RefMet names.
  5. Use the 'New Data Upload' tab to (a) register your study, (b) submit metadata and processed data and (c) upload raw data/supplementary material . (Please read the step-by-step tutorial). Please indicate the date when the study may be made available to the public. If you wish to use the Excel templates instead of the recommended online submission system you must first download the Excel templates for metadata and results (ZIP - Updated 02/24/2015). Complete the metadata and results templates, per the included instructions. Please refer to our template tutorials for a demonstration of how to use the Excel templates.
  6. E-mail us for additional assistance (help@metabolomicsworkbench.org), if needed.

The compressed (zip, 7z, gz) data file is selected and uploaded to the DRCC FTP server through a FTP client. A variety of free and commercial standalone file transfer clients exist to upload large data files directly to the FTP servers: FileZilla, WinSCP, download managers, etc. The usage of FileZilla is recommended for uploading data to the DRCC.

Accessing and reviewing deposited data/metadata on the Metabolomics Workbench

After the DRCC has processed your dataset (typically less than 30 days), you will be notified and may review it at the following private website: http://dev.metabolomicsworkbench.org:22222/data/browse.php

In order to browse and review data and metadata from experimental projects and studies submitted by your institution (or other institutions for which you have permission to view), you will be prompted to login with your Metabolomics Workbench username and password. After you have reviewed your dataset and communicated with the DRCC, the study will be placed on the public Metabolomics Workbench website (subject to its embargo date, if any).