Summary of Study ST000814
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000579. The data can be accessed directly via it's Project DOI: 10.21228/M8TM29 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST000814 |
| Study Title | Hormones & Cognition/Aging/Placebo |
| Study Type | MS analysis |
| Study Summary | The goal is to look at measures of overall metabolic state in relationship to hormonal environment and measures of mood/depression or cognitive function (behavioral and functional MRI images). There are some relationships in this data set between glucose/insulin levels and cognitive function, and we would like to use the untargeted assays to further investigate this relationship. Factors related to visual/spatial memory are included in the design. Factors 1 and 2 (Left Hippocampus, Right Hippocampus) are levels of activation in the hippocampus during a visual memory task, (data missing for some of the samples). Factors 3-5 (BVMT % Retained, BVMT Learning T, BVMT Delay T) are results from a cognitive test of spatial memory function. |
| Institute | University of Michigan |
| Department | Biomedical Research Core Facilities |
| Laboratory | Metabolomics core |
| Last Name | Kachman |
| First Name | Maureen |
| Address | 6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714 |
| mkachman@med.umich.edu | |
| Phone | (734) 232-8175 |
| Submit Date | 2017-07-13 |
| Num Groups | 72 |
| Total Subjects | 28 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | LC-MS |
| Release Date | 2017-10-11 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
| Project ID: | PR000579 |
| Project DOI: | doi: 10.21228/M8TM29 |
| Project Title: | Hormones & Cognition/Aging |
| Project Type: | MS analysis |
| Project Summary: | Untargeted metabolomic assay of early menopause |
| Institute: | University of Michigan |
| Department: | Psychiatry |
| Laboratory: | Berent-Spillson Lab |
| Last Name: | Berent-Spillson |
| First Name: | Alison |
| Address: | Ann Arbor, MI |
| Email: | berent@umich.edu |
| Phone: | 734-717-6399 |
Subject:
| Subject ID: | SU000840 |
| Subject Type: | HUMAN |
| Subject Species: | Homo sapiens |
| Taxonomy ID: | 9606 |
| Species Group: | Human |
Factors:
Subject type: HUMAN; Subject species: Homo sapiens (Factor headings shown in green)
| mb_sample_id | local_sample_id | Factor |
|---|---|---|
| SA045134 | S00014759 | data |
| SA045135 | S00014760 | data |
| SA045136 | S00014758 | data |
| SA045137 | S00014757 | data |
| SA045138 | S00014756 | data |
| SA045139 | S00014761 | data |
| SA045140 | S00014763 | data |
| SA045141 | S00014766 | data |
| SA045142 | S00020133 | data |
| SA045143 | S00014765 | data |
| SA045144 | S00014764 | data |
| SA045145 | S00014755 | data |
| SA045146 | S00014762 | data |
| SA045147 | S00014754 | data |
| SA045148 | S00014745 | data |
| SA045149 | S00014746 | data |
| SA045150 | S00014744 | data |
| SA045151 | S00014743 | data |
| SA045152 | S00014741 | data |
| SA045153 | S00014742 | data |
| SA045154 | S00014747 | data |
| SA045155 | S00014748 | data |
| SA045156 | S00014752 | data |
| SA045157 | S00014753 | data |
| SA045158 | S00014751 | data |
| SA045159 | S00014750 | data |
| SA045160 | S00014749 | data |
| SA045161 | S00014740 | data |
| Showing results 1 to 28 of 28 |
Collection:
| Collection ID: | CO000834 |
| Collection Summary: | none |
| Sample Type: | Blood |
Treatment:
| Treatment ID: | TR000854 |
| Treatment Summary: | -none |
Sample Preparation:
| Sampleprep ID: | SP000847 |
| Sampleprep Summary: | - |
| Sampleprep Protocol Filename: | A003_-_Untargeted_Metabolomics.pdf |
Combined analysis:
| Analysis ID | AN001288 | AN001289 |
|---|---|---|
| Analysis type | MS | MS |
| Chromatography type | Reversed phase | Reversed phase |
| Chromatography system | Agilent | Agilent |
| Column | Waters Acquity HSS T3 (50 x 2.1mm,1.8um) | Waters Acquity HSS T3 (50 x 2.1mm,1.8um) |
| MS Type | ESI | ESI |
| MS instrument type | QTOF | QTOF |
| MS instrument name | Agilent 6530 QTOF | Agilent 6530 QTOF |
| Ion Mode | NEGATIVE | POSITIVE |
| Units | peak area | peak area |
Chromatography:
| Chromatography ID: | CH000904 |
| Instrument Name: | Agilent |
| Column Name: | Waters Acquity HSS T3 (50 x 2.1mm,1.8um) |
| Chromatography Type: | Reversed phase |
MS:
| MS ID: | MS001181 |
| Analysis ID: | AN001288 |
| Instrument Name: | Agilent 6530 QTOF |
| Instrument Type: | QTOF |
| MS Type: | ESI |
| Ion Mode: | NEGATIVE |
| Analysis Protocol File: | A003_-_Untargeted_Metabolomics.pdf |
| MS ID: | MS001182 |
| Analysis ID: | AN001289 |
| Instrument Name: | Agilent 6530 QTOF |
| Instrument Type: | QTOF |
| MS Type: | ESI |
| Ion Mode: | POSITIVE |
| Analysis Protocol File: | A003_-_Untargeted_Metabolomics.pdf |
