Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Caloric Restriction vs drugs (Study ST000090)

MS negative ion mode (Analysis AN000144)

Metabolite	Structure	F1	F2	F3	F4	F5
TAUROCHENODEOXYCHOLATE (*)	ME657656	0.71	2.51	0.88	0.52	0.32
THREONATE (*)	ME657659	0.33	3.74	0.17	0.77	0.26
CATECHOL	ME657589	2.07	0.67	0.72	0.75	0.76
INDOLEPROPIONATE (*)	ME657614	2.52	0.68	0.33	0.62	0.59
TAUROCHOLATE (*)	ME657657	1.23	1.50	1.27	0.72	0.32
7-ALPHA-HYDROXY-3-OXO-4-CHOLESTENOATE (*)	ME657572	1.32	1.39	0.75	0.72	0.75
INDICAN	ME657613	1.21	1.60	0.75	0.58	0.85
INOSINE 5`-DIPHOSPHATE	ME657616	1.29	0.72	0.91	1.21	0.86
SPHINGOSINE 1-PHOSPHATE (*)	ME657652	1.23	0.69	0.42	1.34	1.17
N-ETHYLMALEIMIDE	ME657637	0.84	1.48	0.90	0.65	1.03
STEARIDONATE (*)	ME657653	0.82	1.58	1.02	0.63	0.91
15(S)-HETE (*)	ME657551	0.43	1.66	0.94	1.02	0.70
ADP-RIBOSE	ME657577	0.64	1.52	0.95	0.87	0.98
LAURIC ACID	ME657618	0.58	1.54	1.01	0.79	1.06
MYRISTIC ACID	ME657627	0.47	1.52	1.07	0.81	1.09
MYRISTOLEIC ACID	ME657628	0.45	1.66	1.17	0.81	0.82
PALMITOLEIC ACID	ME657642	0.38	1.62	1.08	0.92	0.96
AZELAIC ACID	ME657583	0.83	0.96	1.06	1.20	0.95
THIAMINE	ME657658	0.88	0.86	1.20	1.09	0.97
AMINOHYDROXYBUTANOIC ACID	ME657578	0.92	0.59	1.20	1.20	1.07
HEXOSE	ME657609	1.02	0.72	1.02	1.05	1.19
FORMYL-L-METHIONINE	ME657600	1.00	0.71	1.14	1.10	1.02
METHIONINE	ME657623	0.94	0.76	1.12	1.10	1.08
PYRUVATE	ME657650	0.97	0.81	1.06	1.06	1.05
N-ACETYL-L-LEUCINE	ME657634	1.08	0.86	0.86	0.71	1.48
AMINOPENTANOIC ACID	ME657579	0.96	0.94	0.98	0.85	1.26
DOPAMINE 3-O-SULFATE (*)	ME657598	0.89	1.00	1.01	0.85	1.24
GLUTAMINE	ME657606	1.11	0.80	0.90	0.84	1.31
5-OXO-PROLINE	ME657571	1.02	0.80	0.95	0.92	1.32
N-ACETYLNEURAMINATE	ME657636	1.01	0.83	0.95	0.93	1.27
MELATONIN	ME657622	1.15	0.83	1.00	1.04	1.05
THYMIDINE	ME657660	1.18	0.89	1.04	0.89	1.03
METHYL BETA-D-GALACTOSIDE	ME657624	1.25	0.84	0.86	1.02	1.04
GLUCONIC ACID	ME657604	1.12	0.92	0.76	1.06	1.15
13(S)-HPODE (*)	ME657550	1.05	0.92	0.93	0.96	1.14
ACONITATE (*)	ME657573	1.10	0.96	0.88	1.06	1.01
CITRATE	ME657592	1.12	0.89	0.88	1.04	1.09
SERINE	ME657651	0.83	1.18	0.83	1.05	1.18
3-METHYL-2-OXOBUTANOIC ACID (*)	ME657561	0.82	1.10	0.95	0.98	1.06
5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5`-MONOPHOSPHATE	ME657569	0.84	1.16	0.92	1.04	1.02
HYPOXANTHINE	ME657612	0.91	1.10	0.90	1.04	1.05
ADENOSINE	ME657575	0.65	1.24	0.88	1.04	1.09
CORTISOL 21-ACETATE	ME657593	0.74	1.16	0.95	1.16	1.03
PREGN STEROID MONOSULFATE (*)	ME657647	0.93	0.89	0.91	1.21	1.10
MYO-INOSITOL	ME657626	0.91	0.93	0.90	1.09	1.16
3-HYDROXY-3-METHYLGLUTARATE	ME657559	0.92	0.98	0.94	1.06	1.08
LACTATE	ME657617	0.93	0.99	0.89	1.07	1.10
MALATE	ME657620	0.98	1.14	0.73	1.10	1.03
TAURINE	ME657655	1.00	1.02	0.87	1.17	0.95
2-HYDROXYGLUTARATE (*)	ME657554	0.97	1.11	0.88	1.05	0.98
FUMARIC ACID	ME657601	0.99	1.07	0.86	1.08	1.00
3-(2-HYDROXYPHENYL)PROPANOATE	ME657557	1.11	1.11	1.17	0.82	0.85
2`-DEOXYCYTIDINE	ME657552	0.90	1.10	1.14	0.86	0.99
B-ALANYL-N(PAI)-METHYL-L-HISTIDINE	ME657584	0.84	1.08	1.11	0.81	1.07
CINNAMIC ACID	ME657590	1.03	0.91	1.14	0.85	1.10
5,6-DIHYDROURACIL	ME657568	0.86	0.96	1.17	0.92	1.09
BOC-ASN	ME657585	0.86	0.92	1.19	0.93	1.10
[C13] TYROSINE	ME657548	0.94	1.00	1.12	0.92	1.03
DEOXYURIDINE	ME657596	0.88	1.00	1.14	0.88	1.09
PHENYLALANINE	ME657646	0.93	1.00	1.16	0.86	1.06
ARGININE	ME657581	0.93	0.96	1.16	0.89	1.06
[C13] PHENYLALANINE	ME657547	0.93	0.96	1.16	0.89	1.06
CIS-7,10,13,16-DOCOSATETRAENOIC ACID	ME657591	1.01	1.03	0.99	1.05	0.92
HEPTANOIC ACID	ME657607	0.99	1.10	1.00	1.02	0.88
CYTIDINE	ME657594	0.99	1.08	1.11	0.98	0.85
PANTOTHENIC ACID	ME657643	0.99	1.15	1.05	0.88	0.93
URATE	ME657666	0.96	1.15	1.02	0.93	0.92
2-OXO-3-HYDROXY-4-PHOSPHOBUTANOATE (*)	ME657556	0.95	1.09	1.05	0.95	0.95
3-(4-HYDROXYPHENYL)LACTATE	ME657558	0.95	1.05	1.10	0.94	0.97
N(PAI)-METHYL-L-HISTIDINE	ME657629	0.89	1.01	1.04	1.02	1.04
(S)-LACTATE	ME657546	0.95	0.96	1.04	0.99	1.06
LL-2,6-DIAMINOHEPTANEDIOATE	ME657619	0.95	1.12	1.00	0.89	1.02
4-HYDROXY-2-QUINOLINECARBOXYLIC ACID	ME657564	0.98	1.07	1.01	0.90	1.05
ASPARTATE	ME657582	0.95	1.08	0.99	0.92	1.06
4-AMINOBENZOATE	ME657563	1.00	1.09	0.94	0.95	1.04
NONANOATE	ME657639	0.98	1.04	1.00	0.95	1.03
PENTITOL	ME657644	1.01	1.03	0.98	0.96	1.01
5-HYDROXYINDOLE-3-ACETIC ACID	ME657570	0.98	1.00	1.00	0.91	1.10
BOC-PHE-OH	ME657587	0.99	1.00	1.01	0.90	1.11
BOC-ASP-OH	ME657586	0.95	1.07	1.07	0.84	1.06
URIDINE	ME657667	1.01	1.06	1.01	0.85	1.07
DECANOATE	ME657595	0.90	1.14	0.97	0.91	1.05
HYDROXYDECANOATE (*)	ME657611	0.86	1.20	0.96	0.92	1.03
N-ACETYL-D-HEXOSAMINE	ME657631	0.90	1.20	0.99	0.91	0.98
GAMMA-GLUTAMYLTHREONINE (*)	ME657602	0.88	1.13	1.04	0.89	1.05
TRYPTOPHAN (*)	ME657663	0.88	1.11	1.08	0.87	1.06
CAPRYLIC ACID	ME657588	0.89	1.13	1.05	0.94	0.99
EDTA	ME657599	0.90	1.09	1.04	0.92	1.03
MALEIMIDE	ME657621	0.92	1.08	1.03	0.94	1.01
4-VINYLPHENOL SULFATE (*)	ME657567	1.07	0.97	1.00	0.82	1.11
[C13] VALINE	ME657549	1.05	1.02	1.06	0.89	1.00
URACIL	ME657665	1.13	0.99	1.05	0.86	0.92
TRYPTOPHANAMIDE	ME657664	1.05	1.06	0.88	0.95	1.05
ADENINE	ME657574	1.05	1.16	0.99	0.82	0.99
TRIDECANOIC ACID	ME657662	1.13	1.11	0.92	0.83	1.02
HIPPURATE	ME657610	1.15	1.22	0.80	0.73	1.09
PYRIDOXAL	ME657649	0.94	1.30	0.77	0.73	1.18
OCTADECANEDIOATE (*)	ME657640	0.98	1.24	0.91	0.88	0.96
ORNITHINE	ME657641	1.05	1.23	0.94	0.85	0.90
INOSINE	ME657615	0.96	1.32	0.85	0.92	0.85
METHYLMALONATE	ME657625	1.04	1.34	0.81	0.90	0.93
SUCCINATE	ME657654	0.99	1.26	0.81	0.97	0.95
2-HYDROXYQUINOLINE	ME657555	0.81	1.45	0.89	0.97	0.84
GLUCURONOLACTONE	ME657605	1.00	1.38	1.00	0.89	0.72
AMINOPROPIONIC ACID / SARCOSINE	ME657580	0.73	1.23	1.23	0.93	0.87
HEXANOATE	ME657608	0.76	1.23	1.17	0.91	0.94
GAMMA-LINOLENIC ACID	ME657603	0.97	1.35	0.97	0.70	0.99
N-ACETYLGLYCINE	ME657633	1.01	1.36	0.88	0.76	0.98
2`-DEOXYURIDINE 5`-MONOPHOSPHATE	ME657553	1.06	1.21	1.02	0.70	1.03
N-ACETYL-L-PHENYLALANINE	ME657635	0.95	1.22	1.04	0.72	1.07
PHENYLACETATE (*)	ME657645	0.91	1.16	0.98	0.81	1.13
PROLINE	ME657648	0.83	1.19	0.99	0.81	1.16
4-PYRIDOXATE	ME657566	0.92	1.32	0.89	0.85	1.02
N-ACETYL-D-TRYPTOPHAN	ME657632	0.89	1.26	0.90	0.84	1.09
THYMIDINE 5`-MONOPHOSPHATE	ME657661	0.89	1.22	0.93	0.88	1.07
N-OLEOYLGLYCINE	ME657638	0.81	1.23	1.03	0.85	1.07
N(PAI)-METHYL-L-HISTIDINE (*)	ME657630	0.79	1.21	1.08	0.80	1.07
3-METHOXY-L-TYROSINE	ME657560	0.76	1.19	1.05	0.87	1.03
ADENOSINE 5`-MONOPHOSPHATE	ME657576	0.73	1.26	1.08	0.87	1.03
DODECENOATE (*)	ME657597	0.72	1.37	0.97	0.76	1.08
3-METHYL-2-OXOVALERIC ACID	ME657562	0.79	1.31	1.06	0.74	1.07
4-METHYL-2-OXO-PENTANOIC ACID	ME657565	0.79	1.32	1.11	0.69	1.07

Factors:

F1	Treatment:Acarbose
F2	Treatment:Caloric restriction
F3	Treatment:Control
F4	Treatment:Estrogen
F5	Treatment:Rapamycin

Data matrix