Clustering data with hclust algorithm for A study of changes in lipid metabolism of ovarian cancer cells co-cultured with adipocytes: UPLC-QTRAP MS analysis (Study ST000096)
Oxylipins analysis,Negative (Analysis AN000152)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 |
|---|---|---|---|---|---|---|---|
| PGD2 | ME658239 | 1.10 | 0.18 | 3.87 | 0.42 | 0.54 | 0.16 |
| 9,10-13-TriHOME | ME658226 | 1.23 | 0.14 | 4.23 | 0.56 | 0.08 | 0.04 |
| 9,12,13-TriHOME | ME658229 | 1.29 | 0.18 | 4.14 | 0.54 | 0.08 | 0.05 |
| 15-HETrE | ME658199 | 3.06 | 1.46 | 0.57 | 0.77 | 0.03 | 0.23 |
| 12(13)-EpOME | ME658179 | 3.21 | 1.67 | 0.53 | 0.51 | 0.12 | 0.22 |
| 9(10)-EpOME | ME658225 | 3.20 | 1.75 | 0.49 | 0.48 | 0.11 | 0.23 |
| 9-HODE | ME658232 | 3.54 | 1.06 | 0.21 | 0.35 | 0.03 | 0.35 |
| 12,13-DiHOME | ME658181 | 3.38 | 0.83 | 0.96 | 0.49 | 0.22 | 0.37 |
| 13-KODE | ME658188 | 3.19 | 1.12 | 0.88 | 0.54 | 0.14 | 0.35 |
| 9,10-DiHOME | ME658228 | 3.51 | 1.09 | 0.86 | 0.34 | 0.31 | 0.15 |
| 9-KODE | ME658235 | 3.69 | 1.06 | 0.64 | 0.48 | 0.07 | 0.29 |
| 8-HETE | ME658223 | 1.63 | 0.57 | 0.60 | 1.45 | 0.08 | 1.49 |
| 5-HETE | ME658215 | 2.41 | 0.71 | 0.31 | 0.84 | 0.10 | 1.36 |
| 11-HETE | ME658176 | 2.16 | 1.14 | 0.50 | 1.12 | 0.07 | 1.13 |
| 5-KETE | ME658217 | 2.16 | 0.94 | 0.35 | 1.06 | 0.05 | 1.37 |
| 6-keto PGF1a | ME658218 | 1.48 | 0.64 | 2.28 | 0.71 | NA | 0.08 |
| PGE2 | ME658241 | 1.59 | 0.47 | 2.93 | 0.50 | 0.42 | 0.27 |
| 12(13)-Ep-9-KODE | ME658177 | 2.82 | 0.72 | 1.65 | 0.77 | 0.11 | 0.19 |
| PGF2a | ME658243 | 2.85 | 0.24 | 2.18 | 0.30 | 0.31 | 0.15 |
| TXB2 | ME658247 | 1.32 | NA | 1.73 | NA | 0.08 | NA |
| 11,12,15-THET | ME658174 | 1.05 | NA | 1.99 | NA | 0.10 | NA |
| PGE1 | ME658240 | 0.88 | NA | 1.89 | NA | 0.37 | NA |
| 15-deoxy PGJ2 | ME658196 | 0.89 | NA | 1.62 | NA | 0.58 | NA |
| 17,18-DiHETE | ME658204 | 0.63 | NA | 1.58 | NA | 0.89 | NA |
| PGE3 | ME658242 | 0.54 | NA | 1.69 | NA | 0.91 | NA |
| 19,20-DiHDoPA | ME658207 | 0.83 | NA | 1.35 | NA | 0.92 | NA |
| 8(9)-EpETrE | ME658220 | 0.59 | NA | 1.38 | NA | 1.04 | NA |
| 14(15)-EpETE | ME658189 | 0.63 | NA | 1.02 | NA | 1.35 | NA |
| 5-HpETE | ME658216 | 0.90 | NA | 1.05 | NA | 1.01 | NA |
| 6-trans-LTB4 | ME658219 | 1.13 | NA | 0.96 | NA | 0.91 | NA |
| 5,6-DiHETrE | ME658213 | 2.10 | NA | 0.20 | NA | 0.09 | NA |
| 9,10-DiHODE | ME658227 | 2.40 | NA | 0.53 | NA | 0.18 | NA |
| Lipoxin A4 | ME658236 | 2.36 | NA | 0.68 | NA | 0.07 | NA |
| 13-HOTE | ME658186 | 2.75 | NA | 0.33 | NA | 0.05 | NA |
| 12(13)-EpODE | ME658178 | 2.66 | NA | 0.40 | NA | 0.08 | NA |
| 9(10)-EpODE | ME658224 | 2.65 | NA | 0.38 | NA | 0.10 | NA |
| 9-HOTE | ME658233 | 2.37 | NA | 0.19 | NA | 0.04 | NA |
| 15(16)-EpODE | ME658194 | 2.50 | NA | 0.33 | NA | 0.04 | NA |
| 17-HDoHE | ME658205 | 2.49 | NA | 0.25 | NA | 0.13 | NA |
| 12-HEPE | ME658182 | 1.51 | NA | 0.88 | NA | 0.66 | NA |
| 15-KETE | ME658201 | 1.66 | NA | 0.82 | NA | 0.60 | NA |
| 14-HDoHE | ME658193 | 2.08 | NA | 0.60 | NA | 0.41 | NA |
| 5-HEPE | ME658214 | 1.99 | NA | 0.51 | NA | 0.35 | NA |
| 5,15-DiHETE | ME658212 | 1.77 | NA | 0.68 | NA | 0.38 | NA |
| 8,9-DiHETrE | ME658222 | 1.84 | NA | 0.70 | NA | 0.25 | NA |
| 14,15-DiHETE | ME658191 | 1.31 | NA | 1.24 | NA | 0.48 | NA |
| PGJ2/ d 12-PGJ2 | ME658244 | 1.25 | NA | 1.23 | NA | 0.56 | NA |
| 15,16-DiHODE | ME658195 | 1.88 | NA | 1.22 | NA | 0.04 | NA |
| 11,12-DiHETrE | ME658175 | 1.56 | NA | 1.45 | NA | 0.12 | NA |
| 14,15-DiHETrE | ME658192 | 1.43 | NA | 1.11 | NA | 0.05 | NA |
| 4-HDoHE | ME658211 | NA | 0.47 | NA | 0.96 | NA | 1.49 |
| 12-HpETE | ME658184 | 0.23 | 1.60 | 0.06 | 2.07 | 0.05 | 1.71 |
| 9-HETE | ME658231 | 0.80 | 0.61 | 0.21 | 1.87 | 0.15 | 2.33 |
| 9-HpODE | ME658234 | 0.04 | 4.08 | 0.00 | 1.14 | 0.00 | 0.60 |
| 13-HpODE | ME658187 | 0.10 | 3.31 | 0.01 | 1.79 | 0.01 | 1.03 |
| 15-HpETE | ME658200 | 0.09 | 3.28 | 0.04 | 1.39 | 0.02 | 1.32 |
| 15-HEPE | ME658197 | 1.36 | 1.68 | 0.65 | 1.68 | 0.50 | 0.43 |
| 11(12)-EpETrE | ME658173 | 1.73 | 2.32 | 0.37 | 1.05 | 0.07 | 0.80 |
| 13-HODE | ME658185 | 2.31 | 2.28 | 0.38 | 1.06 | 0.02 | 0.20 |
| 12-HETE | ME658183 | 1.25 | 2.55 | 0.48 | 1.54 | 0.06 | 0.38 |
| 15-HETE | ME658198 | 1.43 | 3.28 | 0.17 | 1.21 | 0.02 | 0.16 |
Factors:
| F1 | Sample Type:Adipocyte | Timepoint:18 hours |
| F2 | Sample Type:Adipocyte | Timepoint:4 hours |
| F3 | Sample Type:Co-culture | Timepoint:18 hours |
| F4 | Sample Type:Co-culture | Timepoint:4 hours |
| F5 | Sample Type:Control | Timepoint:18 hours |
| F6 | Sample Type:Control | Timepoint:4 hours |
