Clustering data with hclust algorithm for Metabolic analysis of Normal Mouse Lung Fiboblasts with/without TGFbeta treatment (Part 1) (Study ST000143)
ESI negative ion mode (Analysis AN000226)| Metabolite | Structure | F1 | F2 | F3 | F4 |
|---|---|---|---|---|---|
| Nicotinamide Adenine Dinucleotide reduced | ME685040 | 1.07 | 1.04 | NA | 0.93 |
| Acetyl-CoA | ME685030 | 0.56 | 1.41 | 0.59 | 1.12 |
| Adenosine monophosphate | ME685032 | 0.53 | 1.52 | 0.41 | 1.40 |
| Dihydronicotinamide-adenine dinucleotide phosphate | ME685042 | 0.62 | 0.74 | 1.18 | 1.31 |
| Sucrose | ME685044 | 0.96 | 0.86 | 1.33 | 0.93 |
| Nicotinamide adenine dinucleotide phosphate | ME685041 | 0.88 | 0.95 | 0.89 | 1.25 |
| Adenosine diphosphate | ME685031 | 0.99 | 1.02 | 1.05 | 0.95 |
| Flavin adenine dinucleotide | ME685036 | 0.98 | 1.02 | 0.98 | 1.02 |
| Citrate or Isocitrate | ME685034 | 1.30 | 0.46 | 2.13 | 0.40 |
| 6-Phosphogluconate | ME685029 | 1.48 | 0.55 | 1.64 | 0.49 |
| Phosphoenolpyruvate | ME685043 | 1.48 | 0.56 | 1.65 | 0.29 |
| 2 or 3-phosphoglycerate | ME685028 | 1.44 | 0.77 | 1.31 | 0.56 |
| Adenosine triphosphate | ME685033 | 1.13 | 0.69 | 1.66 | 0.68 |
| Glucose 6-phosphate or fructose-6-phosphate | ME685035 | 1.35 | 0.66 | 1.41 | 0.69 |
| Fructose 1,6-bisphosphate | ME685037 | 1.24 | 0.69 | 1.46 | 0.72 |
| Malate | ME685038 | 1.28 | 0.64 | 1.48 | 0.72 |
Factors:
| F1 | Genotype:parp1 ko | Treatment:bleomycin |
| F2 | Genotype:parp1 ko | Treatment:saline |
| F3 | Genotype:parp1 wt | Treatment:bleomycin |
| F4 | Genotype:parp1 wt | Treatment:saline |
