Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for 13C mass isotopomer analysis (LCMS flux studies) MLL-AF9 (part II) (Study ST000157)

ESI/QTOF negative ion mode (Analysis AN000448)

Metabolite	Structure	F1	F2	F3	F4	F5	F6
Fructose 1,6-bisphosphate_13C_2	ME696504	0.32	3.28	0.37	2.77	0.05	NA
Glucose 6-phosphate or fructose-6-phosphate_13C_2	ME696515	0.85	2.22	0.35	3.74	0.19	0.24
Glucose 6-phosphate or fructose-6-phosphate_13C_4	ME696517	0.42	2.21	0.26	3.69	0.16	0.20
Fructose 1,6-bisphosphate_13C_4	ME696506	0.02	1.07	0.03	1.90	NA	NA
Fructose 1,6-bisphosphate_13C_3	ME696505	NA	0.24	0.09	2.25	0.16	NA
Glucose 6-phosphate or fructose-6-phosphate_13C_5	ME696518	NA	0.06	0.00	1.97	NA	NA
Adenosine triphosphate_13C_4	ME696489	NA	0.15	0.40	3.11	NA	0.04
Adenosine triphosphate_13C_2	ME696487	0.16	0.30	1.03	2.92	NA	NA
Adenosine triphosphate_13C_3	ME696488	0.25	0.15	1.27	3.37	0.05	0.38
Adenosine monophosphate_13C_4	ME696478	0.17	1.39	0.81	4.13	0.04	0.48
Adenosine diphosphate_13C_4	ME696472	0.13	0.77	0.69	3.95	NA	0.28
Adenosine monophosphate_13C_5	ME696479	0.11	0.50	0.57	3.95	NA	0.29
Adenosine diphosphate_13C_2	ME696470	0.28	0.81	1.05	3.67	0.17	0.27
Adenosine diphosphate_13C_3	ME696471	0.46	0.61	1.33	3.68	0.09	0.49
Glucose 6-phosphate or fructose-6-phosphate_13C_3	ME696516	0.10	1.72	0.26	3.07	NA	0.33
Erythrose 4-phosphate_13C_2	ME696500	0.33	0.97	0.12	2.75	0.00	NA
Sedoheptulose 7-phosphate_13C_4	ME696565	0.18	1.01	0.20	3.24	NA	0.37
Glucose 6-phosphate or fructose-6-phosphate_13C_1	ME696514	0.58	2.16	0.87	2.11	0.49	0.60
Ribose-5-phosphate or xylulose 5-phosphate_13C_2	ME696557	0.51	1.88	1.24	2.40	0.19	0.44
Malate_13C_4	ME696537	0.53	1.29	1.18	2.57	0.49	0.66
Adenosine monophosphate_13C_2	ME696476	0.29	1.34	1.12	3.34	0.11	0.81
Adenosine monophosphate_13C_3	ME696477	0.43	0.93	1.23	3.02	0.20	0.93
Sedoheptulose 7-phosphate_13C_3	ME696564	0.06	0.91	1.00	2.34	NA	0.18
Ribose-5-phosphate or xylulose 5-phosphate_13C_4	ME696559	0.13	1.53	1.08	2.89	0.07	0.19
Sedoheptulose 7-phosphate_13C_2	ME696563	0.11	1.36	1.15	3.03	0.06	0.17
Ribose-5-phosphate or xylulose 5-phosphate	ME696555	1.53	1.89	0.96	0.71	0.70	0.24
Sedoheptulose 7-phosphate	ME696561	1.50	1.98	0.85	0.73	0.80	0.26
3-Glycerophosphate	ME696520	1.17	1.62	1.13	0.95	0.40	0.72
Malate	ME696449	1.26	1.66	1.10	1.04	0.63	0.43
6-Phosphogluconate	ME696458	1.12	1.78	0.79	1.15	0.92	0.58
Sucrose	ME696453	1.46	1.83	0.72	1.21	0.74	0.33
Adenosine monophosphate	ME696474	1.51	1.75	0.83	1.05	0.64	0.37
Glutamate	ME696524	1.45	1.58	0.87	1.13	0.70	0.39
3-phosphoglyceraldehyde_13C_2	ME696511	1.17	2.18	0.95	1.24	0.36	0.54
3-phosphoglyceraldehyde	ME696509	1.41	2.39	0.59	1.29	0.66	0.10
Erythrose 4-phosphate	ME696498	1.30	2.42	0.65	1.26	0.72	0.22
Fructose 1,6-bisphosphate	ME696448	1.01	3.12	0.95	0.99	0.48	0.17
Glucose 6-phosphate or fructose-6-phosphate	ME696513	1.65	2.67	0.51	0.66	0.74	0.16
Fructose 1,6-bisphosphate_13C_1	ME696503	NA	1.49	0.82	0.87	NA	NA
Sedoheptulose 7-phosphate_13C_6	ME696567	NA	2.16	0.20	0.57	0.70	NA
Citrate or Isocitrate_13C_3	ME696494	0.30	2.34	0.65	0.96	0.09	NA
Sedoheptulose 7-phosphate_13C_5	ME696566	0.18	3.06	0.33	0.52	0.00	NA
Citrate or Isocitrate_13C_1	ME696492	0.92	NA	1.26	0.43	1.34	NA
Citrate or Isocitrate_13C_5	ME696496	0.04	NA	2.15	NA	1.38	1.01
Citrate or Isocitrate_13C_6	ME696497	0.58	0.80	1.04	0.59	1.56	1.35
Nicotinamide Adenine Dinucleotide reduced_13C_3	ME696549	1.19	NA	1.19	0.62	NA	NA
Sedoheptulose 7-phosphate_13C_1	ME696562	0.69	1.02	1.84	0.75	0.39	0.79
Aspartate	ME696480	1.17	0.74	1.52	0.68	0.78	0.70
Citrate or Isocitrate	ME696491	1.28	0.80	1.06	0.64	0.96	0.96
Nicotinamide Adenine Dinucleotide oxidized	ME696450	1.93	0.48	1.99	0.68	0.07	0.35
Adenosine diphosphate	ME696468	1.64	1.38	1.00	1.36	0.38	0.26
Adenosine triphosphate	ME696485	1.54	0.99	1.21	1.65	0.31	0.26
Citrate or Isocitrate_13C_2	ME696493	1.67	0.87	1.32	1.43	0.21	0.27
Acetyl-CoA	ME696465	1.14	0.55	1.42	1.05	0.46	0.11
Nicotinamide Adenine Dinucleotide reduced	ME696451	1.17	0.88	1.78	0.99	0.11	0.20
Sucrose_13C_1	ME696569	0.82	NA	1.17	1.15	0.08	1.48
Glucose 6-phosphate or fructose-6-phosphate_13C_6	ME696519	0.29	0.71	2.38	0.91	NA	NA
Aspartate_13C_1	ME696481	0.37	0.18	2.49	0.62	0.26	0.85
Aspartate_13C_2	ME696482	0.51	0.42	2.31	1.14	0.15	1.09
Erythrose 4-phosphate_13C_1	ME696499	NA	NA	1.25	1.19	0.56	NA
Aspartate_13C_3	ME696483	0.20	0.03	1.88	1.23	NA	0.37
Malate_13C_3	ME696536	0.26	0.25	1.56	1.53	NA	0.10
Ribose-5-phosphate or xylulose 5-phosphate_13C_3	ME696558	0.36	0.94	1.60	1.99	0.32	0.50
Glutamate_13C_2	ME696526	0.95	1.09	1.55	1.85	0.24	0.47
Malate_13C_2	ME696535	0.66	1.07	1.83	1.93	0.20	0.47
Malate_13C_1	ME696534	0.40	0.42	2.18	1.58	0.15	0.69
Glutamate_13C_1	ME696525	0.76	0.46	1.80	1.78	0.29	0.56
Ribose-5-phosphate or xylulose 5-phosphate_13C_1	ME696556	0.58	0.80	1.86	1.38	0.31	0.63
Glutamate_13C_3	ME696527	0.13	0.17	1.77	2.18	NA	0.41
Glutamate_13C_4	ME696528	NA	0.18	1.09	2.02	NA	0.20
Adenosine diphosphate_13C_1	ME696469	0.50	0.53	1.86	2.68	0.17	0.56
Adenosine monophosphate_13C_1	ME696475	0.47	0.59	1.72	2.20	0.29	0.93
Adenosine triphosphate_13C_1	ME696486	0.44	0.24	1.39	2.00	0.05	0.84

Factors:

F1	Cell type:AMPKαfl/fl \| Labeling time, min:5 \| 1,2-13C2-labeled glucose concentration, g/L:0.2
F2	Cell type:AMPKαfl/fl \| Labeling time, min:5 \| 1,2-13C2-labeled glucose concentration, g/L:2
F3	Cell type:AMPKαfl/fl \| Labeling time, min:60 \| 1,2-13C2-labeled glucose concentration, g/L:0.2
F4	Cell type:AMPKαfl/fl \| Labeling time, min:60 \| 1,2-13C2-labeled glucose concentration, g/L:2
F5	Cell type:AMPKαΔ/Δ \| Labeling time, min:5 \| 1,2-13C2-labeled glucose concentration, g/L:0.2
F6	Cell type:AMPKαΔ/Δ \| Labeling time, min:60 \| 1,2-13C2-labeled glucose concentration, g/L:0.2

Data matrix