Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Metabolomic analysis of normal and diabetic mouse bone marrow under PBS or metformin treatment (Study ST000164)

ESI negative ion mode (Analysis AN000257)

Metabolite	Structure	F1	F2	F3	F4
Cinnamic acid	ME697084	3.73	0.30	0.34	0.31
Phosphonopyruvate	ME697108	0.30	0.35	2.31	0.86
Ascorbic acid	ME697072	0.05	1.98	0.09	1.65
Dihydrouracil	ME697109	1.58	1.37	0.56	0.63
Nicotinuric acid	ME697103	1.54	1.37	0.70	0.52
L-Homocysteic acid	ME696992	0.62	1.58	0.94	0.76
Formylmethionine	ME697078	0.79	1.55	0.76	0.85
Glucuronic acid	ME697056	0.73	1.52	0.84	0.84
Oxalic acid	ME697075	1.17	0.76	0.91	1.20
Lauric acid	ME696991	1.49	0.80	0.87	0.96
Mannitol	ME697088	1.44	0.85	0.90	0.92
Hydantoin-5-propionic acid	ME697104	0.96	1.05	1.20	0.78
Hydroxypyruvic acid	ME697112	1.03	1.06	1.25	0.66
ADMA	ME697027	1.11	1.14	0.89	0.89
Tryptophan	ME697017	1.05	1.17	0.92	0.87
Cytosine	ME696998	1.25	1.15	0.88	0.79
Guanidineacetic acid	ME697051	1.19	1.14	0.97	0.75
Cysteine	ME697004	1.04	1.30	0.71	0.96
CMP	ME697014	1.06	1.29	0.87	0.79
Histidinol	ME697032	0.99	1.33	0.85	0.83
4-Hydroxypyridine	ME697098	0.97	0.87	1.14	1.01
Ketoleucine	ME697039	1.01	0.89	1.11	0.99
Proline betaine	ME697095	1.07	1.01	1.05	0.89
Propionyl-L-carnitine	ME697002	1.07	1.08	0.97	0.90
Sucrose	ME697031	1.13	1.03	0.98	0.89
Sedoheptulose 7-phosphate	ME697107	0.98	1.07	1.00	0.96
Pyrrole-2-carboxylic acid	ME697113	1.01	1.03	0.94	1.02
ketoisovaleric acid	ME697096	1.06	1.00	0.99	0.97
N-Acetylcadaverine	ME696990	1.08	0.99	0.98	0.98
Aspartic acid b-semialdehyde	ME697053	1.01	1.00	1.02	0.97
Hydroxyisobutyric acid	ME697086	1.03	0.97	1.02	1.00
3-Indoleacetic Acid	ME697089	1.18	0.98	0.83	1.06
Butyric acid	ME697044	1.13	1.02	0.88	0.99
5-Aminoimidazole-4-carboxamide	ME697106	1.26	1.09	0.78	0.93
Thymine	ME697030	1.16	1.10	0.81	0.97
Fucose	ME697094	1.25	0.81	0.98	1.03
Myristic acid	ME697062	1.28	0.95	0.92	0.92
Pentadecylic acid	ME697073	1.20	0.94	0.94	0.97
3-methyl pyruvic acid	ME697110	0.88	0.92	0.75	1.43
ADP	ME697074	0.75	1.00	0.70	1.48
Glutathione	ME697008	0.39	0.98	0.91	1.56
Thymidine	ME697058	0.53	1.17	0.87	1.31
Creatine	ME697025	0.60	1.00	0.87	1.42
Creatinine	ME697067	0.59	1.04	0.82	1.45
Citric acid	ME697055	0.72	1.38	0.73	1.11
Pantothenic Acid	ME697036	0.72	1.25	0.79	1.17
Glucose	ME696989	0.80	1.28	0.78	1.09
Aconitic acid	ME697054	0.72	1.33	0.80	1.08
Glycolic acid	ME697079	0.70	1.29	0.83	1.10
Threonate	ME697070	0.57	1.30	0.85	1.17
Glutamate	ME696999	0.62	1.20	0.88	1.20
2-(a-D-Mannosyl)-3-phosphoglycerate	ME697065	0.67	1.20	0.90	1.15
Pyrroline hydroxycarboxylic acid	ME697061	0.67	1.21	0.90	1.14
Fumarate	ME697060	0.69	1.25	0.89	1.09
Malic acid	ME697057	0.67	1.24	0.92	1.09
Homocysteinesulfinic acid	ME697064	0.68	1.38	0.90	0.95
Gulonic acid	ME697080	0.74	1.33	0.96	0.90
Uric acid	ME697046	0.79	1.31	0.89	0.96
Coumaric acid	ME697038	0.82	1.23	0.98	0.93
Glyceraldehyde 3-phosphate	ME696994	0.88	1.25	0.94	0.90
Erythrulose	ME697077	0.88	1.15	0.93	1.01
Hydroxy-L-glutamic acid	ME697006	0.93	1.15	0.97	0.93
Pyruvate	ME697068	0.89	1.17	0.81	1.10
Ribose	ME697087	0.90	1.22	0.80	1.05
Oxoglutaric acid	ME697063	0.77	1.22	0.91	1.04
Tartaric acid	ME697069	0.81	1.25	0.85	1.04
Adenosine	ME697052	0.75	0.76	0.93	1.49
Hydroxyhydroquinone	ME696996	0.76	0.87	0.94	1.37
Adenine	ME697111	0.83	0.85	0.97	1.31
N-Acetyl-D-glucosamine	ME697101	0.83	0.79	0.96	1.38
Citrulline	ME697035	0.88	0.74	1.15	1.20
Hypoxanthine	ME697041	0.67	0.76	1.20	1.29
Glutathione, oxidized	ME697024	0.78	0.80	1.06	1.30
Inosine	ME697050	0.74	0.76	1.13	1.30
Glucose 6-phosphate	ME697020	0.63	0.85	1.39	1.04
Uracil	ME697090	0.78	0.91	1.28	0.97
Glycerol 2-phosphate	ME697099	0.74	0.89	1.23	1.08
Ribose 5-phosphate	ME697037	0.80	0.86	1.17	1.12
Maleamic acid	ME697085	0.85	1.12	0.86	1.13
D-Glycerate 3-phosphate	ME697092	0.86	1.07	0.82	1.21
Glycerol	ME697047	0.82	1.05	0.86	1.23
Ornithine	ME696993	0.81	1.06	0.97	1.12
Arachidonic Acid	ME697049	0.75	1.05	0.95	1.19
Uridine	ME697081	0.75	1.09	0.95	1.15
3-Hydroxy-L-proline	ME697029	0.76	1.02	1.00	1.16
Sarcosine	ME697048	0.71	1.04	1.00	1.18
Proline	ME697028	0.65	1.11	0.89	1.26
N-acetylaspartate	ME697000	0.72	1.08	0.91	1.22
Guanosine	ME697082	0.74	1.02	0.91	1.27
Taurine	ME697003	0.71	1.05	0.91	1.26
Pipecolic acid	ME697102	0.96	0.90	1.01	1.13
2-Keto-glutaramic acid	ME697097	0.86	0.90	1.06	1.14
UMP	ME697034	0.87	1.00	1.00	1.09
Glutaric acid	ME697076	0.84	0.97	1.04	1.11
Taurocyamine	ME697091	0.82	0.98	1.00	1.15
Oxaloacetate	ME697105	1.04	0.96	0.89	1.12
Aminobutyric acid	ME697100	0.93	1.01	0.89	1.15
Pyridoxal (Vitamin B6)	ME697040	0.96	1.01	0.89	1.13
AMP	ME697033	0.83	0.96	0.94	1.23
Threonine	ME697019	0.93	0.95	0.88	1.23
Succinic acid semialdehyde	ME697026	0.80	1.08	1.11	0.96
Xanthine	ME697093	0.75	0.98	1.16	1.05
Phosphatidyl glycerol	ME697071	0.72	1.05	1.18	0.98
Tyrosine	ME697009	0.67	1.03	1.17	1.05
Cytidine	ME697021	0.67	1.13	1.06	1.07
IMP	ME697045	0.71	1.09	1.03	1.10
D-Erythrose 4-phosphate	ME697066	0.71	1.17	1.09	0.96
Lactic acid	ME697059	0.72	1.21	1.00	1.00
Hypotaurine	ME696995	0.47	0.91	1.12	1.37
Histidine	ME697005	0.64	0.99	1.12	1.16
N-Carbamoylputrescine	ME697015	0.59	1.04	1.15	1.12
Valine	ME696997	0.61	1.03	1.13	1.14
Isoleucine	ME697016	0.64	1.03	1.13	1.10
Phenylalanine	ME697007	0.62	1.06	1.14	1.09
Lysine	ME697011	0.51	1.00	1.11	1.25
Arginine	ME697023	0.53	1.07	1.11	1.17
Methionine	ME697013	0.51	1.03	1.15	1.18
Serine	ME697012	0.60	0.94	1.15	1.21
Alanine	ME697010	0.65	1.00	1.06	1.20
Aspartate	ME697001	0.60	1.03	1.05	1.22
Asparagine	ME697022	0.61	0.98	1.05	1.26
Glutamine	ME697018	0.56	0.96	1.08	1.29
Aminolevulinic Acid	ME697083	0.73	0.91	1.06	1.23
Glyceric acid	ME697043	0.61	0.95	0.99	1.35
O-Phosphorylethanolamine	ME697042	0.65	1.01	0.97	1.29

Factors:

F1	Mice health condition:MKR \| Treatment:Metformin
F2	Mice health condition:MKR \| Treatment:PBS buffer
F3	Mice health condition:wild type \| Treatment:Metformin
F4	Mice health condition:wild type \| Treatment:PBS buffer

Data matrix