Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Liver and Plasma metaboites for 13C-glucose load in wild type, LIRKO GTT 1 mice (Study ST000215)

ESI negative ion mode (Analysis AN000317)

Metabolite	Structure	F1	F2	F3	F4	F5	F6
Adenosine monophosphate_13C_4	ME698118	3.35	1.82	1.17	1.14	0.94	0.38
Adenosine diphosphate_13C_2	ME698111	2.34	1.25	1.99	0.43	0.99	0.54
2 or 3-phosphoglycerate_13C_3	ME698099	1.32	0.96	2.55	0.29	0.91	NA
2 or 3-phosphoglycerate_2PG/3PG	ME698096	1.16	1.21	3.10	0.82	1.13	0.45
Adenosine diphosphate_13C_3	ME698112	0.32	2.57	0.97	NA	0.71	0.75
Adenosine monophosphate_13C_5	ME698119	NA	1.56	1.43	0.32	1.07	NA
2 or 3-phosphoglycerate_13C_2	ME698098	0.56	0.84	1.78	1.43	0.26	NA
Acetyl-CoA_13C_1	ME698108	NA	0.29	1.45	1.10	1.31	0.70
3-phosphoglyceraldehyde	ME698142	0.25	0.37	0.32	1.64	1.49	0.67
Citrate or Isocitrate_13C_6	ME698136	0.34	NA	0.67	1.40	0.79	1.37
Adenosine diphosphate_13C_4	ME698113	1.08	1.26	0.84	1.75	1.28	0.26
Citrate or Isocitrate_13C_1	ME698131	1.69	0.97	1.25	1.23	1.31	0.02
Citrate or Isocitrate_13C_2	ME698132	1.91	0.95	0.92	1.34	1.65	0.01
6-Phosphogluconate_13C_1	ME698101	0.79	0.42	1.35	0.15	1.43	NA
Aspartate_13C_4	ME698124	0.45	0.29	1.17	0.69	1.34	NA
6-Phosphogluconate_13C_5	ME698105	0.69	NA	0.81	0.33	1.23	NA
6-Phosphogluconate_13C_6	ME698106	0.75	NA	0.97	0.32	1.19	NA
Adenosine monophosphate_13C_2	ME698116	0.76	0.63	1.08	0.56	1.96	0.35
Aspartate	ME698120	1.00	0.73	0.83	1.02	1.57	0.52
Malate	ME698147	1.04	0.87	0.70	1.13	1.48	0.36
6-Phosphogluconate	ME698100	1.04	0.72	0.64	0.68	1.73	0.57
Glutamate	ME698145	0.76	0.60	0.71	0.80	1.44	0.72
Ribose-5-phosphate or xylulose 5-phosphate	ME698152	0.74	0.61	0.76	0.84	1.41	0.78
Citrate or Isocitrate_13C_3	ME698133	1.30	0.68	0.70	0.99	1.11	NA
Citrate or Isocitrate_13C_4	ME698134	1.08	0.66	0.89	1.07	1.18	0.12
6-Phosphogluconate_13C_2	ME698102	0.56	0.52	0.50	0.67	1.70	NA
Aspartate_13C_3	ME698123	0.90	0.51	0.49	0.76	1.43	NA
Aspartate_13C_1	ME698121	0.98	0.68	0.76	0.90	1.53	0.02
Aspartate_13C_2	ME698122	1.12	0.61	0.60	0.93	1.69	0.08
Adenosine diphosphate_13C_1	ME698110	0.73	0.93	1.64	1.12	1.16	0.43
Adenosine monophosphate_13C_3	ME698117	1.09	1.21	1.19	1.01	1.68	0.20
Fructose 1,6-bisphosphate	ME698141	1.06	1.16	1.90	0.38	0.94	1.21
Lactate	ME698146	1.67	0.35	0.76	0.59	1.31	1.13
Nicotinamide Adenine Dinucleotide oxidized	ME698149	1.10	0.76	1.06	1.00	0.50	1.87
Nicotinamide Adenine Dinucleotide reduced	ME698150	1.05	0.61	1.32	1.24	0.66	1.21
Glucose 6-phosphate or fructose-6-phosphate	ME698143	1.78	1.08	0.73	1.14	0.86	0.98
Acetyl-CoA	ME698107	1.32	1.16	1.15	1.23	0.76	0.96
ADP	ME698139	1.70	1.29	1.25	0.97	0.72	1.05
ATP	ME698140	1.68	1.34	1.30	0.79	0.76	1.11
Erythrose 4-phosphate	ME698137	0.68	0.70	0.69	1.08	1.18	1.22
Sucrose	ME698154	0.92	0.88	0.85	1.37	1.00	0.57
Sedoheptulose 7-phosphate	ME698153	1.00	0.89	0.99	0.92	1.13	0.88
AMP	ME698138	1.34	0.92	1.02	1.11	0.98	0.89
3-Glycerophosphate	ME698144	1.06	1.00	0.97	1.24	1.00	0.72
Citrate or Isocitrate	ME698130	1.15	0.90	0.98	1.11	1.17	0.76

Factors:

F1	treatment:glucose \| Strain:IRF floxed
F2	treatment:glucose \| Strain:IR floxed
F3	treatment:glucose \| Strain:IR floxed
F4	treatment:glucose \| Strain:LIRFKO
F5	treatment:glucose \| Strain:LIRKO
F6	treatment:none \| Strain:IR floxed

Data matrix