Summary of Study ST003131

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001945. The data can be accessed directly via it's Project DOI: 10.21228/M89M7J This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST003131
Study TitleUntargeted Metabolomics on mouse caecal contents
Study TypeMouse
Study SummaryWhile there is strong evidence for interactions between the microbiota-gut-brain axis and host physiology in the context of chronic stress, limited research has investigated the role of the microbiome in host response to acute stress. Determining the underlying mechanisms by which stress-induced microbiota changes may provoke functional changes in the gut and brain is critical for developing future therapeutics to alleviate the adverse consequences of traumatic stress. Here, we aimed to identify a biological signature of gut metabolites that are significantly altered following exposure to acute restraint stress. Adult male C57Bl/6 conventional, germ-free and colonized germ-free mice underwent a 15-minute restraint stress exposure. Caecal contents were collected from naïve mice and stressed mice, either immediately or 45 minutes following stress. Caecal contents underwent untargeted metabolomics analysis.
Institute
University College Cork
DepartmentPsychiatry
LaboratoryMicrobiota-Gut-Brain Axis Group
Last NameClarke
First NameGerard
AddressGaol Walk, Cork
EmailG.Clarke@ucc.ie
Phone+353-21-4901408
Submit Date2024-03-19
Num Groups9
Total Subjects63
Num Males63
Analysis Type DetailOther
Release Date2024-03-22
Release Version1
Gerard Clarke Gerard Clarke
https://dx.doi.org/10.21228/M89M7J
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Sample source Factor
SA339176ColGF10Caecal Contents ColGF_0min
SA339177ColGF11Caecal Contents ColGF_0min
SA339178ColGF8Caecal Contents ColGF_0min
SA339179ColGF6Caecal Contents ColGF_0min
SA339180ColGF5Caecal Contents ColGF_0min
SA339181ColGF12Caecal Contents ColGF_0min
SA339182ColGF7Caecal Contents ColGF_0min
SA339183ColGF20Caecal Contents ColGF_45min
SA339184ColGF21Caecal Contents ColGF_45min
SA339185ColGF19Caecal Contents ColGF_45min
SA339186ColGF18Caecal Contents ColGF_45min
SA339187ColGF17Caecal Contents ColGF_45min
SA339188ColGF9Caecal Contents ColGF_45min
SA339189ColGF16Caecal Contents ColGF_45min
SA339190ColGF3Caecal Contents ColGF_Pre
SA339191ColGF1Caecal Contents ColGF_Pre
SA339192ColGF4Caecal Contents ColGF_Pre
SA339193ColGF2Caecal Contents ColGF_Pre
SA339194ColGF14Caecal Contents ColGF_Pre
SA339195ColGF13Caecal Contents ColGF_Pre
SA339196ColGF15Caecal Contents ColGF_Pre
SA339197Conv17Caecal Contents Conv_0min
SA339198Conv16Caecal Contents Conv_0min
SA339199Conv19Caecal Contents Conv_0min
SA339200Conv22Caecal Contents Conv_0min
SA339201Conv13Caecal Contents Conv_0min
SA339202Conv21Caecal Contents Conv_0min
SA339203Conv18Caecal Contents Conv_0min
SA339204Conv8Caecal Contents Conv_45min
SA339205Conv7Caecal Contents Conv_45min
SA339206Conv9Caecal Contents Conv_45min
SA339207Conv14Caecal Contents Conv_45min
SA339208Conv15Caecal Contents Conv_45min
SA339209Conv6Caecal Contents Conv_45min
SA339210Conv10Caecal Contents Conv_45min
SA339211Conv3Caecal Contents Conv_Pre
SA339212Conv1Caecal Contents Conv_Pre
SA339213Conv20Caecal Contents Conv_Pre
SA339214Conv12Caecal Contents Conv_Pre
SA339215Conv2Caecal Contents Conv_Pre
SA339216Conv4Caecal Contents Conv_Pre
SA339217Conv5Caecal Contents Conv_Pre
SA339218GF7Caecal Contents GF_0min
SA339219GF15Caecal Contents GF_0min
SA339220GF16Caecal Contents GF_0min
SA339221GF6Caecal Contents GF_0min
SA339222GF17Caecal Contents GF_0min
SA339223GF5Caecal Contents GF_0min
SA339224GF4Caecal Contents GF_0min
SA339225GF18Caecal Contents GF_45min
SA339226GF20Caecal Contents GF_45min
SA339227GF8Caecal Contents GF_45min
SA339228GF11Caecal Contents GF_45min
SA339229GF19Caecal Contents GF_45min
SA339230GF10Caecal Contents GF_45min
SA339231GF9Caecal Contents GF_45min
SA339232GF3Caecal Contents GF_Pre
SA339233GF2Caecal Contents GF_Pre
SA339234GF12Caecal Contents GF_Pre
SA339235GF1Caecal Contents GF_Pre
SA339236GF21Caecal Contents GF_Pre
SA339237GF14Caecal Contents GF_Pre
SA339238GF13Caecal Contents GF_Pre
Showing results 1 to 63 of 63
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