Summary of Study ST001815
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001148. The data can be accessed directly via it's Project DOI: 10.21228/M89Q5T This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST001815 |
Study Title | Metabolic Markers of Methotrexate Response in Juvenile Idiopathic Arthritis |
Study Type | Clinical |
Study Summary | Plasma from children with juvenile idiopathic arthritis collected pre-treatment and following 3 months of treatment with methotrexate were submitted for metabolomic profiling to the NIH West Coast Metabolomics Center. |
Institute | University of Kansas |
Department | Pharmacy Practice |
Laboratory | Funk Lab |
Last Name | funk |
First Name | ryan |
Address | 2106 Olathe Boulevard |
ryanfunk@kumc.edu | |
Phone | 9135885000 |
Submit Date | 2021-05-18 |
Num Groups | 1 |
Total Subjects | 30 |
Num Males | 9 |
Num Females | 21 |
Analysis Type Detail | GC-MS/LC-MS |
Release Date | 2021-06-17 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
Analysis ID | AN002944 | AN002945 | AN002946 | AN002947 |
---|---|---|---|---|
Analysis type | MS | MS | MS | MS |
Chromatography type | GC | HILIC | Reversed phase | Reversed phase |
Chromatography system | Leco Pegasus IV GC | Agilent 6530 | Agilent 6530 | Agilent 6530 |
Column | Restek Rtx-5Sil (30m x 0.25mm,0.25um) | Waters Acquity BEH Amide (150 x 2.1mm,1.7um) | Waters Acquity CSH C18 (100 x 2.1mm,1.7um) | Waters Acquity CSH C18 (100 x 2.1mm,1.7um) |
MS Type | EI | ESI | ESI | ESI |
MS instrument type | GC-TOF | QTOF | QTOF | QTOF |
MS instrument name | Leco Pegasus IV TOF | Agilent 6530 QTOF | Agilent 6530 QTOF | Agilent 6550 QTOF |
Ion Mode | NEGATIVE | POSITIVE | POSITIVE | NEGATIVE |
Units | Peak Height Intensity | Peak Height Intensity | Peak Height Intensity | Peak Height Intensity |
Chromatography:
Chromatography ID: | CH002180 |
Chromatography Summary: | Primary Metabolism |
Instrument Name: | Leco Pegasus IV GC |
Column Name: | Restek Rtx-5Sil (30m x 0.25mm,0.25um) |
Chromatography Type: | GC |
Chromatography ID: | CH002181 |
Chromatography Summary: | Biogenic Amines |
Instrument Name: | Agilent 6530 |
Column Name: | Waters Acquity BEH Amide (150 x 2.1mm,1.7um) |
Chromatography Type: | HILIC |
Chromatography ID: | CH002182 |
Chromatography Summary: | Lipidomics |
Instrument Name: | Agilent 6530 |
Column Name: | Waters Acquity CSH C18 (100 x 2.1mm,1.7um) |
Column Temperature: | 65 |
Flow Rate: | 0.6 mL/min |
Solvent A: | 60% acetonitrile/40% water; 0.1% formic acid; 10 mM ammonium formate |
Solvent B: | 90% isopropanol/10% acetonitrile; 0.1% formic acid; 10 mM ammonium formate |
Chromatography Type: | Reversed phase |