Summary of Study ST002196
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001400. The data can be accessed directly via it's Project DOI: 10.21228/M8RM5T This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002196 |
Study Title | Metabolic signature of idiopathic inflammatory myopathy |
Study Summary | Objective of this study was to find Metabolic signature of idiopathic inflammatory myopathy (IIM). We used the serum samples of healthy control, IIM, ankylosing spondylitis. Metabolites were quantified using biocrates p180 kit. First, we found IIM specific metabolites by using ANOVA with post-hoc analysis. With set of metabolite panel, we made prediction model using logistic regression (LR), support vector machine (SVM), and random forest (RF). We found 7 metabolites as biomarker for classifying IIM from healthy control and ankylosing spondylitis. Also, we validate our model using 5 cross validation method. Out set of metabolites showed the AUC values of 0.955 (LR), 0.908 (RF) and 0.918 (SVM). |
Institute | Seoul National University |
Last Name | Kang |
First Name | Jihyun |
Address | 502ho Intergrative Biomedical Education Research Building, 101 Deahakro, Jongro-gu, Seoul, 03080, Korea, South Korea |
jikang@snu.ac.kr | |
Phone | +821071014069 |
Submit Date | 2022-06-09 |
Raw Data Available | Yes |
Raw Data File Type(s) | wiff |
Analysis Type Detail | LC-MS |
Release Date | 2022-07-14 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
Analysis ID | AN003595 |
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Analysis type | MS |
Chromatography type | Reversed phase |
Chromatography system | AB SCIEX QTRAP 5500 |
Column | Waters ACQUITY UPLC BEH C18 (75 x 2.1mm,1.7um) |
MS Type | ESI |
MS instrument type | Triple quadrupole |
MS instrument name | ABI Sciex 5500 QTrap |
Ion Mode | POSITIVE |
Units | ng/mL |
Chromatography:
Chromatography ID: | CH002656 |
Instrument Name: | AB SCIEX QTRAP 5500 |
Column Name: | Waters ACQUITY UPLC BEH C18 (75 x 2.1mm,1.7um) |
Solvent A: | 100% water; 0.2% formic acid |
Solvent B: | 100% acetonitrile; 0.2% formic acid |
Chromatography Type: | Reversed phase |