Summary of Study ST002803
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001750. The data can be accessed directly via it's Project DOI: 10.21228/M8H71B This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002803 |
| Study Title | Early life metabolic abnormalities in the bone marrow of the offspring of obese mothers |
| Study Summary | Obese mothers predispose their babies to develop metabolic disorders and obesity before they are even born. The study used a mouse model of maternal high-fat diet-induced obesity that recapitulates cardiovascular and metabolic abnormalities seen in humans born to obese mothers. to compare the metabolic characteristics of bone marrow cells in newly weaned mice. The results showed that the bone marrow of offspring born to mothers on a high-fat diet primarily used glucose through OXPHOS and presented decreased amino acid metabolism. These metabolic changes were observed in the bone marrow of the offspring at a very young age before any symptomatic metabolic disease was present. |
| Institute | Oregon Health and Science University |
| Department | Knight Cardiovascular Institute |
| Laboratory | Maloyan Lab |
| Last Name | Maloyan |
| First Name | Alina |
| Address | 3181 S.W. Sam Jackson Park Road, Portland, Oregon, 97239-3098, USA |
| maloyan@ohsu.edu | |
| Phone | 503-494-0012 |
| Submit Date | 2023-07-21 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | cdf |
| Analysis Type Detail | GC-MS |
| Release Date | 2024-06-18 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN004559 |
|---|---|
| Analysis type | MS |
| Chromatography type | GC |
| Chromatography system | Agilent 7890A |
| Column | Restek Rtx-5Sil (30m x 0.25mm,0.25um) |
| MS Type | EI |
| MS instrument type | GC-TOF |
| MS instrument name | Leco GC-TOF |
| Ion Mode | POSITIVE |
| Units | quant m/z |
Chromatography:
| Chromatography ID: | CH003426 |
| Instrument Name: | Agilent 7890A |
| Column Name: | Restek Rtx-5Sil (30m x 0.25mm,0.25um) |
| Column Temperature: | 275 |
| Flow Gradient: | - |
| Flow Rate: | 1 mL/min |
| Solvent A: | - |
| Solvent B: | - |
| Chromatography Type: | GC |
