Summary of Study ST000918
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000634. The data can be accessed directly via it's Project DOI: 10.21228/M8QM3R This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST000918 |
Study Title | Plasma metabolic fingerprint for breast cancer (MS) - part I |
Study Type | control - case |
Study Summary | Breast cancer is a highly heterogeneous disease associated with metabolic reprogramming. The shifts in the metabolome caused by breast cancer still lack data from Latin populations of Hispanic origin. In this pilot study, metabolomic and lipidomic approaches were performed to establish a plasma metabolic fingerprint of Colombian Hispanic women with breast cancer. NMR, GC-MS and LC-MS datasets were combined and compared. Statistics showed discrimination between breast cancer and healthy subjects on all analytical platforms. |
Institute | Universidad de los Andes, Colombia |
Department | Chemistry |
Last Name | Cala |
First Name | Monica |
Address | Cra. 1 #18a-12 |
mp.cala10@uniandes.edu.co | |
Phone | +571 3394949 |
Submit Date | 2017-12-29 |
Num Groups | 2 |
Total Subjects | 58 |
Analysis Type Detail | GC-MS/LC-MS |
Release Date | 2018-02-07 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
Analysis ID | AN001503 | AN001504 | AN001505 |
---|---|---|---|
Analysis type | MS | MS | MS |
Chromatography type | GC | Reversed phase | Reversed phase |
Chromatography system | Agilent | Agilent 1200 | Agilent 1200 |
Column | Zebron ZB-5MSi capillary GC | Phenomenex Kinetex C18 (150 x 2.1mm,2.6um) | Phenomenex Kinetex C18 (150 x 2.1mm,2.6um) |
MS Type | EI | ESI | ESI |
MS instrument type | Single quadrupole | QTOF | QTOF |
MS instrument name | Agilent 5973 | Agilent 6530 QTOF | Agilent 6530 QTOF |
Ion Mode | POSITIVE | POSITIVE | NEGATIVE |
Units | peak area | peak area | peak area |
Chromatography:
Chromatography ID: | CH001060 |
Chromatography Summary: | Untargeted GC/MS method |
Instrument Name: | Agilent |
Column Name: | Zebron ZB-5MSi capillary GC |
Column Temperature: | 0-1 min 60ªC 1-33 min to 320ªC |
Flow Rate: | 1.0 mL/min |
Sample Injection: | 2 uL |
Chromatography Type: | GC |
Chromatography ID: | CH001061 |
Chromatography Summary: | Untargeted LC/MS method |
Chromatography Comments: | HPLC system 1200 series coupled to Q-TOF 6520 |
Instrument Name: | Agilent 1200 |
Column Name: | Phenomenex Kinetex C18 (150 x 2.1mm,2.6um) |
Column Pressure: | 300 bar |
Column Temperature: | 40°C |
Flow Gradient: | 25% B increased then to 95% B in 35 min, returned to initial conditions in 1 min and was kept constant for 9 min to ensure re-equilibration of the column |
Flow Rate: | 0.3 mL/min |
Sample Injection: | 10 uL |
Solvent A: | 100% water; 0.1% formic acid |
Solvent B: | 100% acetonitrile; 0.1% formic acid |
Chromatography Type: | Reversed phase |