Summary of Study ST002777
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001732. The data can be accessed directly via it's Project DOI: 10.21228/M8TQ6V This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002777 |
Study Title | The ECHO Cohort Exposome: First Steps using HHEAR Analysis – An Opportunity for ALL ECHO Cohorts to Contribute Type A Samples – Untargeted Analysis (Project Viva) |
Study Type | Prospective Cohort Study |
Study Summary | Project Viva is a ground breaking longitudinal research study of women and their children. The initial goal of Project Viva was to find ways to improve the health of mothers and children by looking at the effects of mother's diet as well as other factors during pregnancy and after birth. Over the past two decades, Project Viva has expanded its focus to include a wider range of experiences that influence health extending into midlife for the mothers, and young adulthood for their children. Please see projectviva.org or contact Emily Oken at Project_Viva@point32health.org for more information or questions related to the subject characteristics and outcomes. This research was supported by the Environmental influences on Child Health Outcomes (ECHO) Program, Office of The Director, National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Project Viva is an ECHO cohort which is supported by the following ECHO Program Collaborators: ECHO Coordinating Center: Duke Clinical Research Institute, Durham, North Carolina: Smith PB, Newby KL, Benjamin DK; U2C OD023375 ECHO Data Analysis Center: Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland: Jacobson LP; Research Triangle Institute, Durham, North Carolina: Catellier D; U24 OD023382 North Carolina Human Health Exposure Analysis Resource Hub: Research Triangle Institute: Fennell T, University of North Carolina at Chapel Hill: Sumner S, University of North Carolina at Charlotte: Du X; U2C ES030857 Human Health Exposure Analysis Resource Coordinating Center: Westat, Inc., Rockville, Maryland: O’Brien B; U24 ES026539 |
Institute | Harvard Pilgrim Health Care Institute |
Department | Department of Population Medicine |
Last Name | Oken |
First Name | Emily |
Address | 401 Park Drive, Suite 401 East Boston, MA 02215 |
Project_Viva@point32health.org | |
Phone | 617-867-4835 |
Submit Date | 2023-07-10 |
Total Subjects | 1,184 |
Study Comments | HHEAR Project EM20-0011, ECHO Project EC0376 |
Raw Data Available | Yes |
Raw Data File Type(s) | raw(Thermo) |
Chear Study | Yes |
Analysis Type Detail | LC-MS |
Release Date | 2024-07-10 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
Analysis ID | AN004521 |
---|---|
Analysis type | MS |
Chromatography type | Reversed phase |
Chromatography system | Thermo Vanquish |
Column | Waters ACQUITY UPLC HSS T3 (100 x 2.1mm,1.8um) |
MS Type | ESI |
MS instrument type | Orbitrap |
MS instrument name | Thermo Q Exactive HF-X Orbitrap |
Ion Mode | POSITIVE |
Units | Normalized intensity |
Chromatography:
Chromatography ID: | CH003395 |
Chromatography Summary: | Reversed phase |
Instrument Name: | Thermo Vanquish |
Column Name: | Waters ACQUITY UPLC HSS T3 (100 x 2.1mm,1.8um) |
Column Pressure: | 6000-10000 psi |
Column Temperature: | 50 ℃ |
Flow Gradient: | Time(min) Flow Rate %A %B Curve 1. 0 0.4 99.0 1.0 5 2. 1.00 0.4 99.0 1.0 5 3. 16.00 0.4 1.0 99.0 5 4. 19.00 0.4 1.0 99.0 5 5. 19.50 0.4 99.0 1.0 5 6. 22.00 0.4 99.0 1.0 5 |
Flow Rate: | 0.4 mL/min |
Injection Temperature: | 8 ℃ |
Internal Standard: | Tryptophan-d5 |
Solvent A: | 100% water; 0.1% formic acid |
Solvent B: | 100% methanol; 0.1% formic acid |
Analytical Time: | 22 min |
Weak Wash Solvent Name: | 10% methanol/90% water; 0.1% formic acid |
Strong Wash Solvent Name: | 75% 2-Propanol/25% Water; 0.1% formic acid |
Chromatography Type: | Reversed phase |