Summary of Study ST002981

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001857. The data can be accessed directly via it's Project DOI: 10.21228/M8P99M This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002981
Study TitleDevelopmental Neurotoxicity of Deltamethrin Exposure on Hypothalamic Neurogenesis in Embryonic Zebrafish
Study SummaryIn this study, to investigate DM effects at different stages of early life, zebrafish embryos were exposed to DM just before (10-16 hpf), at the onset of (16-24 hpf), at the peak of (24-36 hpf) hypothalamic neurogenesis and across 10-120 hpf with different dosage levels (0, 1, 100, and 250 nM).
Institute
College of Marine Food and Biological Engineering, Jimei University
Last NameGao
First NameLonghua
AddressNo. 185 Yinjiang Road, Jimei District, Xiamen City, Fujian Province, China
Email1932076629@qq.com
Phone18718180398
Submit Date2023-11-12
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2023-11-22
Release Version1
Longhua Gao Longhua Gao
https://dx.doi.org/10.21228/M8P99M
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN004899 AN004900
Analysis type MS MS
Chromatography type Reversed phase Reversed phase
Chromatography system Thermo Dionex Ultimate 3000 Thermo Dionex Ultimate 3000
Column Waters ACQUITY UPLC BEH C18 (100 x 2.1mm,1.7um) Waters ACQUITY UPLC BEH C18 (100 x 2.1mm,1.7um)
MS Type ESI ESI
MS instrument type Orbitrap Orbitrap
MS instrument name Thermo Orbitrap Exploris 120 Thermo Orbitrap Exploris120
Ion Mode POSITIVE NEGATIVE
Units Peak area Peak area

Chromatography:

Chromatography ID:CH003696
Instrument Name:Thermo Dionex Ultimate 3000
Column Name:Waters ACQUITY UPLC BEH C18 (100 x 2.1mm,1.7um)
Column Temperature:55
Flow Gradient:First maintain 32% B for 1.5 minutes, then linearly increase from 1.5 to 15.5 minutes to 85% B, then linearly increase to 97% B at 0.1 minutes, maintain for 18 minutes, and then rapidly decrease to 32% B at 0.1 minutes, equilibrate until the next injection
Flow Rate:0.4 mL/min
Solvent A:Acetonitrile/water (6:4, v/v)
Solvent B:Isopropanol/acetonitrile (9:1, v/v)
Chromatography Type:Reversed phase
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