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MB Sample ID: SA019041
Local Sample ID: | 110702bwasa19_1 |
Subject ID: | SU000417 |
Subject Type: | Human |
Subject Species: | Homo sapiens |
Taxonomy ID: | 9606 |
Age Or Age Range: | 45-74 |
Gender: | M/F |
Human Smoking Status: | Current vs. former |
Species Group: | Human |
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Collection:
Collection ID: | CO000411 |
Collection Summary: | In total, 208 patients with lung cancer were selected from 222 patients with non–small-cell lung cancer (NSCLC) with serum available in the CARET repository from blood draws that occurred up to 12 months before diagnosis. Fourteen patients with insufficient sample available for the study were excluded.Two control individuals who were free of lung cancer were matched to each patient case on age at baseline (5-year groups), sex, baseline smoking status (current v former), and study enrollment phase (pilot [1985 to 1988] or full-scale trial [1989 to 1994], thus accounting for sample storage time). For one patient, only a single control could be matched, resulting in a total of 208 patients and 415 controls included in the study. The samples were divided into two sets; samples from 100 matched sets were used for biomarker discovery (the discovery set), and the remaining 108 matched sets were reserved for validation of markers identified by the discovery efforts (the validation set). All CARET participants provided informed consent at recruitment and throughout follow-up, and the institutional review boards at each of the six study centers approved all study procedures. |
Collection Protocol Filename: | JCO-2015-Wikoff-3880-6.pdf |
Sample Type: | Blood |
Blood Serum Or Plasma: | Plasma |