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MB Sample ID: SA196427
Local Sample ID: | SRC-3 KO ZT4 replicate2 pos |
Subject ID: | SU002162 |
Subject Type: | Mammal |
Subject Species: | Mus musculus |
Taxonomy ID: | 10090 |
Gender: | Male |
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Collection:
Collection ID: | CO002155 |
Collection Summary: | To further define the 12-hour clock lipidome, we used a temporal lipidomics-based approach to identify hepatic lipid species in the mouse whole-liver. To unbiasedly characterize the 12-hour cycling lipidomes regulated by SRC-3, we profiled the temporal characteristics of oscillating lipidomes from adult male SRC-3 WT and KO littermates at 12-16 weeks of age under the same ZT condition (12h:12h LD cycle). We then sampled two biological replicates of mouse liver tissues at a temporal resolution starting at ZT0 and proceeding every four hours for two complete 12-hour cycles to determine whether SRC-3 ablation perturbs the 12-hour clock lipidome. |
Sample Type: | Liver |