Summary of Study ST001675

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001078. The data can be accessed directly via it's Project DOI: 10.21228/M8C111 This work is supported by NIH grant, U2C- DK119886.

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Study IDST001675
Study TitleQuantitative measurements of ceramides and glycosphingolipids in Th17 and iTreg cells (part-II)
Study TypeMS: Targeted analysis
Study SummaryPart 2/5: It includes quantitative targeted measurements of sphingolipids (ceramides and glycosphingolipids) in Th17, iTreg, and their paired controls (Th0 cells).
Institute
University of Turku
DepartmentSystems Medicine, Turku Bioscience
LaboratoryMetabolomics
Last NameSen
First NamePartho
AddressTykistökatu 6B, BioCity, 5th Floor
Emailpartho.sen@utu.fi
Phone0469608145
Submit Date2021-01-31
Raw Data AvailableYes
Raw Data File Type(s)mzML
Analysis Type DetailLC-MS
Release Date2021-11-02
Release Version1
Partho Sen Partho Sen
https://dx.doi.org/10.21228/M8C111
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Collection:

Collection ID:CO001745
Collection Summary:CD4+ T-cells were isolated from human umbilical cord blood as described previously (Khan et al., 2020; Tripathi et al., 2017; Ubaid et al., 2018). CD4+ T-cells were isolated from human umbilical cord blood as described previously [1-3]. 1. Ubaid, U. et al. Transcriptional Repressor HIC1 Contributes to Suppressive Function of Human Induced Regulatory T Cells. Cell Rep 22, 2094-2106, doi:10.1016/j.celrep.2018.01.070 (2018). 2. Khan, M. M. et al. CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling. iScience 23, 100947, doi:10.1016/j.isci.2020.100947 (2020). 3. Tripathi, S. K. et al. Genome-wide Analysis of STAT3-Mediated Transcription during Early Human Th17 Cell Differentiation. Cell Rep 19, 1888-1901, doi:10.1016/j.celrep.2017.05.013 (2017).
Sample Type:T-cells
Storage Conditions:-80℃
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