Summary of Study ST002418

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001556. The data can be accessed directly via it's Project DOI: 10.21228/M8K429 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002418
Study TitleSerum metabolomics and lipidomics profiling in iliac arteriovenous fistula creation in clinical patients: part 2
Study TypeStudy of the serum metabolome in patients with end stage kidney disease before and 6-weeks after iliac arteriovenous fistula creation via 1H NMR
Study SummaryThis project is focused on a longitudinal analysis of the small molecules metabolomes in end stage renal disease patients undergoing iliac arteriovenous fistula creation using solution state NMR spectroscopy. It was hypothesized that after 6-weeks of AVF creation, these patients would present with altered serum metabolite features.
Institute
University of Florida
DepartmentApplied Physiology and Kinesiology
LaboratoryRm 42 and Rm 43
Last NameKhattri
First NameRam
Address1864 Stadium RD, Gainesville, FL, 32611, USA
Emailrbk11@ufl.edu
Phone3307856045
Submit Date2022-12-22
Num Groups2
Total Subjects45 subjects, 2 samples per subject, total of 90 samples
Num Males36
Num Females9
Study CommentsStudy of the serum metabolome in patients with end stage kidney disease before and 6-weeks after iliac arteriovenous fistula creation via 1H NMR
Raw Data AvailableYes
Raw Data File Type(s)fid
Analysis Type DetailNMR
Release Date2023-12-22
Release Version1
Ram Khattri Ram Khattri
https://dx.doi.org/10.21228/M8K429
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Collection:

Collection ID:CO002500
Collection Summary:Institutional review board (IRB) of the University of Florida reviewed and approved this study. All human subjects included in this study were fully informed about the study, and informed consent were obtained from each of them (IRB#140-2013, IRB#556-2009). Blood samples from ESKD patients were collected at different time points: baseline (pre-operation) and 6-weeks post-op from fistula creation.
Collection Protocol Filename:AVF-NMR_Lipid_Phase_Procedures.docx
Sample Type:Blood (serum)
Collection Method:Serum samples were collected from the patients. The samples were let sit at room temperature for ~45 minutes. Later, the samples were centrifuged for 15 minutes maintaining 2180-rpm speed at 4 oC with brake on. The supernatant from each sample was transfered into a new 15 mL tube and furthermore, aliquoted into a vial (250 uL in each vial). All of the serum samples were stored at -80 oC until analysis.
Storage Conditions:-80℃
Collection Vials:cryovials
Storage Vials:cryovials
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