Summary of Study ST002874
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001796. The data can be accessed directly via it's Project DOI: 10.21228/M8JX52 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002874 |
Study Title | Quantification of metabolites in kynurenine pathway |
Study Summary | Urine samples were collected from two independent cohorts. Patients with LN were classified into proliferative (class III/IV) and membranous (class V) by kidney histopathology. Quantification of metabolites in kynurenine pathway was performed using LC-MS/MS. |
Institute | Mahidol University |
Department | Siriraj Metabolomics and Phenomics Center |
Laboratory | Siriraj Center of Research Excellence in Metabolomics and Systems Biology |
Last Name | Khoomrung |
First Name | Sakda |
Address | 2 Wanglang Road Bangkoknoi, Bangkok 10700, Thailand |
sakda.kho@mahidol.edu | |
Phone | 024195511 |
Submit Date | 2023-09-25 |
Num Groups | 2 |
Total Subjects | 117 |
Publications | https://doi.org/10.1016/j.isci.2021.103355 |
Raw Data Available | Yes |
Raw Data File Type(s) | raw(Waters) |
Analysis Type Detail | LC-MS |
Release Date | 2023-10-10 |
Release Version | 1 |
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Collection:
Collection ID: | CO002980 |
Collection Summary: | Both morning urine and blood samples were collected under sterile conditions within the same day of biopsy/recruitment. Urine samples were centrifuged at 3,500 rpm for 10 min at 4°C. The supernatant was then aliquoted and stored at −80°C until the analysis. Common blood biochemical parameters were measured by an ISO 15189 accredited laboratory. Serum creatinine (SCr) and urine creatinine (UCr) were measured by an enzymatic assay using a Dimension ExL analyzer (Siemens Healthcare Diagnostics, Newark, DE, USA). Urine protein (Uprot) was measured by a modified pyrogallol red-molybdate method. Uprot was reported as urine protein creatinine ratio (UPCR in mg/mgCr). The estimated glomerular filtration rate (eGFR in mL/min/1.73 m2) was calculated using the CKD-EPI equation (Levey et al., 2009): |
Sample Type: | Urine |