Summary of Study ST001003

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000678. The data can be accessed directly via it's Project DOI: 10.21228/M81Q26 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001003
Study TitleA pilot study of urine metabolomics in a female subject towards an outpatient estimate of circadian phase (part I)
Study SummarySerial urine samples were collected at each void (approximately every 3 hours) from subjects during a 6-day inpatient protocol. The total volume of each sample was measured, and then 5 mL was aliquoted into a 7 mL tube and delivered on ice to the processing lab, where the samples were then stored at -80 degrees. At the end of the study, samples were transported (~2 blocks) from the processing lab to our -80 freezer for storage. The samples being sent represent samples from one female subject. This subject spent 6 days in the lab: 3 baseline days where the subject slept for 8 hours at night (at habitual times as determined during the screening period) and 16 hours of ambulatory wake in ambient light, followed by 50 hours of continuous wakefulness in which the subject was kept in a semi-recumbent position in bed under dim light and fed hourly isocaloric snacks (called a constant routine). We are requesting untargeted profiling of 25 samples (sample #: 52919-52943) to determine how the concentrations of different metabolites vary across the 24-hour period, and specifically to compare this circadian variation in each metabolite during a 48-hour ambulatory period versus a 48-hour constant routine period.
Institute
Mayo Clinic
Last NameHilaire
First NameMelissa
Address221 Longwood Avenue, Suite BL438 Boston, Massachusetts 02115
Emailmsthilaire@rics.bwh.harvard.edu
Phone617-732-4013
Submit Date2018-07-10
Analysis Type DetailLC-MS
Release Date2022-12-15
Release Version1
Melissa Hilaire Melissa Hilaire
https://dx.doi.org/10.21228/M81Q26
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Collection:

Collection ID:CO001036
Collection Summary:Serial urine samples were collected at each void (approximately every 3 hours) from subjects during a 6-day inpatient protocol. The total volume of each sample was measured, and then 5 mL was aliquoted into a 7 mL tube and delivered on ice to the processing lab, where the samples were then stored at -80 degrees. At the end of the study, samples were transported (~2 blocks) from the processing lab to our -80 freezer for storage.
Sample Type:Urine
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