Summary of Study ST001846

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001163. The data can be accessed directly via it's Project DOI: 10.21228/M8CH74 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001846
Study TitleProteasome Inhibitor Related Cardiotoxicity (part I)
Study SummaryBALB/c mice were injected with CFZ (16 mg/kg, iv), BTZ (1 mg/kg, iv), CFZ/atRA (CFZ: 16 mg/kg iv, atRA: 1 mg/kg iv) or Captisol (Vehicle, iv) (6 mice per cohort). ECGs were recorded under anesthesia at the end of 1h treatment and the mice were sacrificed by cervical dislocation. Hearts were extracted and were frozen and stored at -80°C until analysis
Institute
University of Zurich
Last NameMendez
First NameMax
AddressRorschacherstrasse 95. 9007, St.Gallen
Emailmaxmendez@runbox.com
Phone+41 71 494 10 67
Submit Date2021-06-01
Num Groups4
Total Subjects24
Num Females24
Raw Data AvailableYes
Raw Data File Type(s)mzXML
Analysis Type DetailLC-MS
Release Date2022-12-01
Release Version1
Max Mendez Max Mendez
https://dx.doi.org/10.21228/M8CH74
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Collection:

Collection ID:CO001916
Collection Summary:Anesthesia was induced with Ketamine 80 mg/kg intramuscular and maintained with Isoflurane 0.5%. Hearts were extracted immediately after cervical dislocation under anesthesia, snap frozen in dry ice and kept at -80°C until analysis.
Sample Type:Cardiac tissue
Storage Conditions:Described in summary
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