Summary of Study ST000051
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000049. The data can be accessed directly via it's Project DOI: 10.21228/M8W88R This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST000051 |
Study Title | Fetal metabolomic signature of exposure to iAs during pregnancy |
Study Type | Metabolomics |
Study Summary | This metabolomics pilot study was aimed to identify a fetal metabolomic signature of exposure to iAs during pregnancy. Fetal cord blood serum was collected immediately after delivery from a saline cleaned umbilical cord using an anticoagulant-free vacutainer tube, after clot formation the tube was centrifuged at 1200 rpm and the serum was collected and stored at -70°C. A subset of 50 cord serum samples were selected from the larger BEAR cohort to represent a wide range of iAs exposure as determined by iAs in drinking water (DW-iAs). The exposure during pregnancy was confirmed using U-tAs. A total of 50 cord blood serum samples were used in the metabolomics analysis The samples included 25 newborns with lower maternal iAs exposure levels (DW < 25?g As/L, mean U-tAs=16 ?g/L) and 25 newborns with higher maternal iAs exposure levels (DW> 25?g As/L, mean U-tAs =107 ?g/L). |
Institute | University of North Carolina |
Department | Systems and Translational Sciences |
Laboratory | Sumner Lab |
Last Name | Sumner |
First Name | Susan |
Address | Eastern Regional Comprehensive Metabolomics Resource Core, UNC Nutrition Research Institute, 500 Laureate Way, Kannapolis, NC, 28081 |
susan_sumner @unc.edu | |
Phone | 704-250-5066 |
Submit Date | 2014-04-30 |
Num Groups | 2 |
Total Subjects | 50 |
Raw Data Available | Yes |
Raw Data File Type(s) | fid |
Uploaded File Size | 31 M |
Analysis Type Detail | NMR |
Release Date | 2018-08-27 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)
mb_sample_id | local_sample_id | As Exposure |
---|---|---|
SA002211 | C-059 | high |
SA002212 | C-062 | high |
SA002213 | C-071 | high |
SA002214 | C-074 | high |
SA002215 | C-058 | high |
SA002216 | C-018 | high |
SA002217 | C-007 | high |
SA002218 | C-104 | high |
SA002219 | C-024 | high |
SA002220 | C-026 | high |
SA002221 | C-031 | high |
SA002222 | C-132 | high |
SA002223 | C-164 | high |
SA002224 | C-187 | high |
SA002225 | C-189 | high |
SA002226 | C-200 | high |
SA002227 | C-134 | high |
SA002228 | C-133 | high |
SA002229 | C-117 | high |
SA002230 | C-120 | high |
SA002231 | C-006 | high |
SA002232 | C-116 | high |
SA002233 | C-005 | high |
SA002234 | C-004 | high |
SA002235 | C-003 | high |
SA002236 | C-095 | low |
SA002237 | C-094 | low |
SA002238 | C-096 | low |
SA002239 | C-098 | low |
SA002240 | C-092 | low |
SA002241 | C-097 | low |
SA002242 | C-085 | low |
SA002243 | C-053 | low |
SA002244 | C-075 | low |
SA002245 | C-081 | low |
SA002246 | C-111 | low |
SA002247 | C-086 | low |
SA002248 | C-115 | low |
SA002249 | C-194 | low |
SA002250 | C-175 | low |
SA002251 | C-197 | low |
SA002252 | C-214 | low |
SA002253 | C-218 | low |
SA002254 | C-167 | low |
SA002255 | C-151 | low |
SA002256 | C-045 | low |
SA002257 | C-123 | low |
SA002258 | C-128 | low |
SA002259 | C-129 | low |
SA002260 | C-113 | low |
SA002205 | CBS-HighP-01R | Pooled-High |
SA002206 | CBS-HighP-02 | Pooled-High |
SA002207 | CBS-LowP-01 | Pooled-Low |
SA002208 | CBS-LowP-02 | Pooled-Low |
SA002209 | CBS-TotalP-01R | Pooled-Total |
SA002210 | CBS-TotalP-02 | Pooled-Total |
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