Summary of Study ST001207
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000811. The data can be accessed directly via it's Project DOI: 10.21228/M8VD62 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST001207 |
Study Title | Lipidomics in the serum of cold exposed mice treated with 12-LOX inhibitor LOXBlock-1 |
Study Summary | We aimed to investigate whether the cold-induced release of 12-LOX products into the circulation were dependent on 12-LOX activation. We pre-treated C57BL6/J mice with the pharmacological inhibitor LOXBlock-1 or its vehicle (DMSO), and after 15 minutes we placed them under cold temperature (5C) for 4 hours. A control group was injected with DMSO and kept at room temperature for the same 4 hours. After this period of time we, collected the blood, and obtained the serum fraction that was immediately frozen and submitted for untargeted lipidomics. |
Institute | Joslin Diabetes Center |
Last Name | Leiria |
First Name | Luiz |
Address | One Joslin Place, Boston-MA, 02215 |
luiz.leiria@joslin.harvard.edu | |
Phone | 617-309-1967 |
Submit Date | 2019-06-26 |
Num Groups | 3 |
Study Comments | Joslin Diabetes Center affiliate of Harvard Medical School |
Raw Data Available | Yes |
Raw Data File Type(s) | wiff |
Analysis Type Detail | LC-MS |
Release Date | 2019-07-17 |
Release Version | 1 |
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Factors:
Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)
mb_sample_id | local_sample_id | Temperature |
---|---|---|
SA084803 | T5 | 22C | Treatment:DMSO |
SA084804 | T6 | 22C | Treatment:DMSO |
SA084805 | T1 | 22C | Treatment:DMSO |
SA084806 | T2 | 22C | Treatment:DMSO |
SA084807 | T3 | 22C | Treatment:DMSO |
SA084808 | T7 | 22C | Treatment:DMSO |
SA084809 | T4 | 22C | Treatment:DMSO |
SA084810 | C4 | 5C | Treatment:DMSO |
SA084811 | C3 | 5C | Treatment:DMSO |
SA084812 | C5 | 5C | Treatment:DMSO |
SA084813 | C6 | 5C | Treatment:DMSO |
SA084814 | C1 | 5C | Treatment:DMSO |
SA084815 | C7 | 5C | Treatment:DMSO |
SA084816 | C2 | 5C | Treatment:DMSO |
SA084817 | LB3 | 5C | Treatment:LoxBlock-1 |
SA084818 | LB1 | 5C | Treatment:LoxBlock-1 |
SA084819 | LB2 | 5C | Treatment:LoxBlock-1 |
SA084820 | LB4 | 5C | Treatment:LoxBlock-1 |
SA084821 | LB5 | 5C | Treatment:LoxBlock-1 |
Showing results 1 to 19 of 19 |