Summary of Study ST001376
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000916. The data can be accessed directly via it's Project DOI: 10.21228/M8912S This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001376 |
| Study Title | 2,3,7,8 -Tetrachlorodibenzo-p-dioxin Mediated Effects on Hepatic Coenzyme A (CoA) and Acetyl-CoA Levels (part-I) |
| Study Type | Dioxin |
| Study Summary | Experiment to study TCDD-elicited effects on hepatic Coenzyme A (CoA) and Acetyl-CoA levels in liver of male mice treated with sesame oil vehicle or 0.01-30 ug/kg TCDD every 4 days for 28 days. |
| Institute | Michigan State University |
| Department | Biochemistry and Molecular Biology |
| Laboratory | Zacharewski Lab |
| Last Name | Fling |
| First Name | Russell |
| Address | 1129 Farm Ln, East Lansing, MI, USA |
| flingrus@msu.edu | |
| Phone | (517) 884-2054 |
| Submit Date | 2020-04-03 |
| Num Groups | 9 |
| Total Subjects | 80 |
| Num Males | 29 |
| Study Comments | Fax: (517) 353-9334; ORCID: 0000-0002-6822-4962; ROLE: Graduate Student; Pubmed ID: -;Publication DOI: -; |
| Publications | - |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Waters) |
| Analysis Type Detail | LC-MS |
| Release Date | 2021-08-02 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Mammalian Subjects; Subject species: Mus musculus (Factor headings shown in green)
| mb_sample_id | local_sample_id | Collection Time |
|---|---|---|
| SA100501 | 8 | Afternoon | TCDD treatment(ug/kg):- |
| SA100502 | 9 | Afternoon | TCDD treatment(ug/kg):- |
| SA100503 | 9_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):- |
| SA100504 | 7 | Afternoon | TCDD treatment(ug/kg):- |
| SA100505 | 10 | Afternoon | TCDD treatment(ug/kg):- |
| SA100506 | 10_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):- |
| SA100507 | 6 | Afternoon | TCDD treatment(ug/kg):- |
| SA100508 | 7_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):- |
| SA100509 | 6_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):- |
| SA100510 | 8_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):- |
| SA100511 | 20 | Afternoon | TCDD treatment(ug/kg):0.01 |
| SA100512 | 18_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.01 |
| SA100513 | 19_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.01 |
| SA100514 | 20_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.01 |
| SA100515 | 19 | Afternoon | TCDD treatment(ug/kg):0.01 |
| SA100516 | 18 | Afternoon | TCDD treatment(ug/kg):0.01 |
| SA100517 | 17_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.01 |
| SA100518 | 17 | Afternoon | TCDD treatment(ug/kg):0.01 |
| SA100519 | 27_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.03 |
| SA100520 | 28_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.03 |
| SA100521 | 30 | Afternoon | TCDD treatment(ug/kg):0.03 |
| SA100522 | 30_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.03 |
| SA100523 | 29_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.03 |
| SA100524 | 26_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.03 |
| SA100525 | 29 | Afternoon | TCDD treatment(ug/kg):0.03 |
| SA100526 | 27 | Afternoon | TCDD treatment(ug/kg):0.03 |
| SA100527 | 26 | Afternoon | TCDD treatment(ug/kg):0.03 |
| SA100528 | 28 | Afternoon | TCDD treatment(ug/kg):0.03 |
| SA100529 | 37_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.1 |
| SA100530 | 38_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.1 |
| SA100531 | 39_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.1 |
| SA100532 | 39 | Afternoon | TCDD treatment(ug/kg):0.1 |
| SA100533 | 37 | Afternoon | TCDD treatment(ug/kg):0.1 |
| SA100534 | 38 | Afternoon | TCDD treatment(ug/kg):0.1 |
| SA100535 | 36_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.1 |
| SA100536 | 36 | Afternoon | TCDD treatment(ug/kg):0.1 |
| SA100537 | 49 | Afternoon | TCDD treatment(ug/kg):0.3 |
| SA100538 | 47_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.3 |
| SA100539 | 48 | Afternoon | TCDD treatment(ug/kg):0.3 |
| SA100540 | 46_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.3 |
| SA100541 | 47 | Afternoon | TCDD treatment(ug/kg):0.3 |
| SA100542 | 48_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.3 |
| SA100543 | 49_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):0.3 |
| SA100544 | 46 | Afternoon | TCDD treatment(ug/kg):0.3 |
| SA100545 | 58 | Afternoon | TCDD treatment(ug/kg):1 |
| SA100546 | 59 | Afternoon | TCDD treatment(ug/kg):1 |
| SA100547 | 60_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):1 |
| SA100548 | 56 | Afternoon | TCDD treatment(ug/kg):1 |
| SA100549 | 60 | Afternoon | TCDD treatment(ug/kg):1 |
| SA100550 | 59_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):1 |
| SA100551 | 56_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):1 |
| SA100552 | 58_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):1 |
| SA100553 | 76 | Afternoon | TCDD treatment(ug/kg):10 |
| SA100554 | 79_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):10 |
| SA100555 | 78_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):10 |
| SA100556 | 77 | Afternoon | TCDD treatment(ug/kg):10 |
| SA100557 | 77_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):10 |
| SA100558 | 79 | Afternoon | TCDD treatment(ug/kg):10 |
| SA100559 | 76_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):10 |
| SA100560 | 80_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):10 |
| SA100561 | 80 | Afternoon | TCDD treatment(ug/kg):10 |
| SA100562 | 78 | Afternoon | TCDD treatment(ug/kg):10 |
| SA100563 | 70 | Afternoon | TCDD treatment(ug/kg):3 |
| SA100564 | 69_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):3 |
| SA100565 | 68_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):3 |
| SA100566 | 67_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):3 |
| SA100567 | 70_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):3 |
| SA100568 | 66 | Afternoon | TCDD treatment(ug/kg):3 |
| SA100569 | 66_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):3 |
| SA100570 | 67 | Afternoon | TCDD treatment(ug/kg):3 |
| SA100571 | 69 | Afternoon | TCDD treatment(ug/kg):3 |
| SA100572 | 68 | Afternoon | TCDD treatment(ug/kg):3 |
| SA100573 | 90 | Afternoon | TCDD treatment(ug/kg):30 |
| SA100574 | 90_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):30 |
| SA100575 | 89 | Afternoon | TCDD treatment(ug/kg):30 |
| SA100576 | 89_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):30 |
| SA100577 | 86 | Afternoon | TCDD treatment(ug/kg):30 |
| SA100578 | 87 | Afternoon | TCDD treatment(ug/kg):30 |
| SA100579 | 86_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):30 |
| SA100580 | 87_1uM_Coa_added | Afternoon | TCDD treatment(ug/kg):30 |
| SA100581 | 5_1uM_Coa_added | Morning | TCDD treatment(ug/kg):- |
| SA100582 | 4_1uM_Coa_added | Morning | TCDD treatment(ug/kg):- |
| SA100583 | 1_1uM_Coa_added | Morning | TCDD treatment(ug/kg):- |
| SA100584 | 3_1uM_Coa_added | Morning | TCDD treatment(ug/kg):- |
| SA100585 | 5 | Morning | TCDD treatment(ug/kg):- |
| SA100586 | 4 | Morning | TCDD treatment(ug/kg):- |
| SA100587 | 3 | Morning | TCDD treatment(ug/kg):- |
| SA100588 | 1 | Morning | TCDD treatment(ug/kg):- |
| SA100589 | 2_1uM_Coa_added | Morning | TCDD treatment(ug/kg):- |
| SA100590 | 2 | Morning | TCDD treatment(ug/kg):- |
| SA100591 | 13 | Morning | TCDD treatment(ug/kg):0.01 |
| SA100592 | 15 | Morning | TCDD treatment(ug/kg):0.01 |
| SA100593 | 11 | Morning | TCDD treatment(ug/kg):0.01 |
| SA100594 | 13_1uM_Coa_added | Morning | TCDD treatment(ug/kg):0.01 |
| SA100595 | 15_1uM_Coa_added | Morning | TCDD treatment(ug/kg):0.01 |
| SA100596 | 11_1uM_Coa_added | Morning | TCDD treatment(ug/kg):0.01 |
| SA100597 | 22 | Morning | TCDD treatment(ug/kg):0.03 |
| SA100598 | 24 | Morning | TCDD treatment(ug/kg):0.03 |
| SA100599 | 23 | Morning | TCDD treatment(ug/kg):0.03 |
| SA100600 | 21 | Morning | TCDD treatment(ug/kg):0.03 |
