Summary of Study ST001928

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001218. The data can be accessed directly via it's Project DOI: 10.21228/M88H76 This work is supported by NIH grant, U2C- DK119886.

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Study IDST001928
Study TitleMetabolomics profiles of premenopausal women are different based on O-desmethylangolensin metabotype
Study SummaryUrinary O-desmethylangolensin (ODMA) concentrations provide a functional gut microbiome marker of dietary isoflavone daidzein metabolism to ODMA. Individuals who do not have gut microbial environments that produce ODMA have less favorable cardiometabolic and cancer risk profiles. Urinary metabolomics profiles were evaluated in relation to ODMA metabotypes within and between individuals over time. Secondary analysis was conducted of data from the BEAN2 trial, which was a cross-over study of premenopausal women consuming six months on a high- and a low-soy diet, each separated by a 1-month washout period. In all of the 672 samples in the study, 66 of the 84 women had the same ODMA metabotype at seven or all eight time points. Two or four urine samples per woman were selected based on temporal metabotypes in order to compare within and across individuals. Metabolomics assays for primary metabolism and biogenic amines were conducted in 60 urine samples from 20 women. Partial least-squares discriminant analysis was used to compare metabolomics profiles.
Institute
George Mason University
Last NameFrankenfeld
First NameCara
Address4400 University Drive, Fairfax, VA 22030
Emailprof.frankenfeld@gmail.com
Phone206-265-2563
Submit Date2021-08-20
Raw Data AvailableYes
Analysis Type DetailLC-MS
Release Date2021-10-29
Release Version1
Cara Frankenfeld Cara Frankenfeld
https://dx.doi.org/10.21228/M88H76
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Organ
SA178426Biorec004Plasma | Treatment:- | Group:- | ODMAmetabotye:-
SA178427Biorec005Plasma | Treatment:- | Group:- | ODMAmetabotye:-
SA178428Biorec003Plasma | Treatment:- | Group:- | ODMAmetabotye:-
SA178429Biorec001Plasma | Treatment:- | Group:- | ODMAmetabotye:-
SA178430Biorec002Plasma | Treatment:- | Group:- | ODMAmetabotye:-
SA178431Biorec006Plasma | Treatment:- | Group:- | ODMAmetabotye:-
SA178420MtdBlank002- | Treatment:- | Group:- | ODMAmetabotye:-
SA178421MtdBlank001- | Treatment:- | Group:- | ODMAmetabotye:-
SA178422MtdBlank004- | Treatment:- | Group:- | ODMAmetabotye:-
SA178423MtdBlank003- | Treatment:- | Group:- | ODMAmetabotye:-
SA178424MtdBlank005- | Treatment:- | Group:- | ODMAmetabotye:-
SA178425MtdBlank006- | Treatment:- | Group:- | ODMAmetabotye:-
SA178432B334u2.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178433B328u8.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178434B328u5.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178435B312u4.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178436B393u2.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178437B434u1.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178438B393u3.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178439B434u5.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178440B407u2.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178441B334u7.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178442B312u3.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178443B455u7.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178444B169u5.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178445B311u8.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178446B169u1.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178447B134u2.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178448B134u1.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178449B455u6.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178450B407u3.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178451B311u6.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Nonproducer
SA178452B134u4.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Producer
SA178453B134u5.2Urine | Treatment:C0 | Group:C0 | ODMAmetabotye:Producer
SA178454B407u5.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178455B455u5.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178456B455u2.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178457B407u6.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178458B434u6.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178459B434u7.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178460B393u1.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178461B312u5.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178462B312u6.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178463B311u2.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178464B169u4.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178465B393u8.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178466B169u6.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178467B328u2.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178468B311u5.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178469B328u3.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178470B334u8.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178471B334u5.2Urine | Treatment:C1 | Group:C1 | ODMAmetabotye:Producer
SA178472B248u2.2Urine | Treatment:NC0 | Group:NC0 | ODMAmetabotye:Nonproducer
SA178473B248u1.2Urine | Treatment:NC0 | Group:NC0 | ODMAmetabotye:Nonproducer
SA178475B199u6.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178476B199u7.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178477B185u2.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178478B234u1.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178479B126u7.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178480B126u2.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178481B105u4.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178482B185u5.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178483B524u8.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178484B431u5.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178485B431u3.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178486B105u3.1Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178487B483u2.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178488B483u7.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178489B532u5.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178490B532u1.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178491B524u6.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178492B234u6.2Urine | Treatment:NC1 | Group:NC1 | ODMAmetabotye:Producer
SA178474B532u4.4Urine | Treatment:NC1 | Group:- | ODMAmetabotye:-
Showing results 1 to 73 of 73
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