Summary of Study ST003073

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001914. The data can be accessed directly via it's Project DOI: 10.21228/M89T5V This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST003073
Study TitleInvestigation of 3,5,3’-L-triiodothyronine (T3) and 3,5,3’5’-L-tetraiodothyronine (T4) by targeted LC-MS analysis from mouse adult or embryonic CSF and from adult serum.
Study SummaryTo maximize discovery from samples with limited amounts, we optimized a method to detect the thyroid hormones ( 3,5,3’-L-triiodothyronine (T3) and 3,5,3’5’-L-tetraiodothyronine (T4)) as well as polar metabolites from central carbon metabolism from mouse adult or embryonic CSF and from adult mouse serum. Samples were ran on reverse phase and HILIC chromatography respectively. For T3 and T4 analysis we utilized targeted analysis using information from previously ran synthetic standards. We interrogated relative changes between fresh and frozen adult (male or female) CSF compared to fresh and frozen embryonic CSF. This data presents the levels of T3 and T4 as interrogated by reverse phase chromatography
Institute
Boston Childrens Hospital
DepartmentPathology
LaboratoryKanarek Lab
Last NamePetrova
First NameBoryana
Address300 Longwood Av
Emailboryana.petrova@childrens.harvard.edu
Phone6173557433
Submit Date2024-01-10
Num Groups7
Total Subjects19
Num Males8
Num Females6
Study Commentsembryos also investigated. samples split for fresh and frozen conditions
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2024-02-14
Release Version1
Boryana Petrova Boryana Petrova
https://dx.doi.org/10.21228/M89T5V
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Sample source
SA332284RF401Adult CSF | Storage condition:Fresh | Sex:Female
SA332285RF402Adult CSF | Storage condition:Fresh | Sex:Female
SA332286RF400Adult CSF | Storage condition:Fresh | Sex:Female
SA332287RF403Adult CSF | Storage condition:Fresh | Sex:Female
SA332288RF398Adult CSF | Storage condition:Fresh | Sex:Male
SA332289RF397Adult CSF | Storage condition:Fresh | Sex:Male
SA332290RF396Adult CSF | Storage condition:Fresh | Sex:Male
SA332291RF399Adult CSF | Storage condition:Fresh | Sex:Male
SA332292RF390Adult CSF | Storage condition:Frozen | Sex:Female
SA332293RF389Adult CSF | Storage condition:Frozen | Sex:Female
SA332294RF387Adult CSF | Storage condition:Frozen | Sex:Female
SA332295RF388Adult CSF | Storage condition:Frozen | Sex:Female
SA332296RF384Adult CSF | Storage condition:Frozen | Sex:Male
SA332297RF383Adult CSF | Storage condition:Frozen | Sex:Male
SA332298RF386Adult CSF | Storage condition:Frozen | Sex:Male
SA332299RF385Adult CSF | Storage condition:Frozen | Sex:Male
SA332300RF381Adult Mock | Storage condition:Fresh | Sex:Female
SA332301RF380Adult Mock | Storage condition:Fresh | Sex:Male
SA332302RF378Adult Mock | Storage condition:Frozen | Sex:Female
SA332303RF377Adult Mock | Storage condition:Frozen | Sex:Male
SA332304RF411Adult Serum | Storage condition:Fresh | Sex:Male
SA332305RF412Adult Serum | Storage condition:Fresh | Sex:Male
SA332306RF410Adult Serum | Storage condition:Frozen | Sex:Male
SA332307RF409Adult Serum | Storage condition:Frozen | Sex:Male
SA332308RF406Embryonic CSF | Storage condition:Fresh | Sex:-
SA332309RF405Embryonic CSF | Storage condition:Fresh | Sex:-
SA332310RF407Embryonic CSF | Storage condition:Fresh | Sex:-
SA332311RF408Embryonic CSF | Storage condition:Fresh | Sex:-
SA332312RF404Embryonic CSF | Storage condition:Fresh | Sex:-
SA332313RF395Embryonic CSF | Storage condition:Frozen | Sex:-
SA332314RF391Embryonic CSF | Storage condition:Frozen | Sex:-
SA332315RF394Embryonic CSF | Storage condition:Frozen | Sex:-
SA332316RF392Embryonic CSF | Storage condition:Frozen | Sex:-
SA332317RF393Embryonic CSF | Storage condition:Frozen | Sex:-
SA332318RF382Embryonic Mock | Storage condition:Fresh | Sex:-
SA332319RF379Embryonic Mock | Storage condition:Frozen | Sex:-
Showing results 1 to 36 of 36
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