Summary of Study ST003256
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002015. The data can be accessed directly via it's Project DOI: 10.21228/M85238 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST003256 |
Study Title | Exploration of Zeb1-dependent changes in the redox-lipidome of MDA-MB-231 cells |
Study Summary | Human breast cancer MDA-MB-231 wildtype (WT) cells and the stably transduced MDA-MB-231 shZeb1 (stable Zeb1 knockdown) and shCtrl cell lines (control cell line for the stable Zeb1 knockdown) (Spaderna et al. 2008, DOI: 10.1158/0008-5472.CAN-07-5682) were treated with DMSO or RSL3 (1 or 10 µM) for 2 h, 4 h, 6 h or 24 h. The cell pellets were collected and analyzed for their oxidized phospholipid profile by UPLC-MS/MS. Please note that one sample set was measured three times with the same sample-ID, but with different methods (Ox-PE, Ox-PC, Ox-PI), therefore each sub-class has their own raw-data file marked by their corresponding abbreviation (Ox-PE, Ox-PC, Ox-PI; e.g. "210514_MDA_ZEB1_oxPE_dil_UD_std_1ul_JZ_oxPE_MRM_003.wiff", "210514_MDA_ZEB1_oxPC_dil_UD_std_1ul_JZ_oxPC_MRM_002.wiff" or "210514_MDA_ZEB1_oxPI_dil_UD_std_1ul_JZ_oxPI_MRM_001.wiff"). |
Institute | University of Innsbruck |
Department | Michael Popp Institute |
Last Name | Koeberle |
First Name | Andreas |
Address | Mitterweg 24, Innsbruck, Tyrol, 6020, Austria |
Andreas.Koeberle@uibk.ac.at | |
Phone | +43 512 507 57903 |
Submit Date | 2024-05-27 |
Raw Data Available | Yes |
Raw Data File Type(s) | wiff |
Analysis Type Detail | LC-MS |
Release Date | 2024-07-05 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Cultured cells; Subject species: Homo sapiens (Factor headings shown in green)
mb_sample_id | local_sample_id | Sample source | Genotype | Treatment | Treatment Time |
---|---|---|---|---|---|
SA353986 | 210514_MDA_ZEB1_n3_2h_sh-Ctrl_DMSO_22 | Breast cancer cells | shCtrl | DMSO | 2 h |
SA353987 | 210514_MDA_ZEB1_n2_2h_sh-Ctrl_DMSO_13 | Breast cancer cells | shCtrl | DMSO | 2 h |
SA353988 | 210514_MDA_ZEB1_n1_2h_sh-Ctrl_DMSO_4 | Breast cancer cells | shCtrl | DMSO | 2 h |
SA353992 | 210514_MDA_ZEB1_n2_2h_sh-Ctrl_RSL3_10_uM_15 | Breast cancer cells | shCtrl | RSL3 (10 µM) | 2 h |
SA353993 | 210514_MDA_ZEB1_n3_2h_sh-Ctrl_RSL3_10_uM_24 | Breast cancer cells | shCtrl | RSL3 (10 µM) | 2 h |
SA353994 | 210514_MDA_ZEB1_n1_2h_sh-Ctrl_RSL3_10_uM_6 | Breast cancer cells | shCtrl | RSL3 (10 µM) | 2 h |
SA353989 | 210514_MDA_ZEB1_n2_2h_sh-Ctrl_RSL3_1_uM_14 | Breast cancer cells | shCtrl | RSL3 (1 µM) | 2 h |
SA353990 | 210514_MDA_ZEB1_n3_2h_sh-Ctrl_RSL3_1_uM_23 | Breast cancer cells | shCtrl | RSL3 (1 µM) | 2 h |
SA353991 | 210514_MDA_ZEB1_n1_2h_sh-Ctrl_RSL3_1_uM_5 | Breast cancer cells | shCtrl | RSL3 (1 µM) | 2 h |
SA353995 | 210514_MDA_ZEB1_n2_2h_sh-ZEB1_DMSO_16 | Breast cancer cells | shZeb1 | DMSO | 2 h |
SA353996 | 210514_MDA_ZEB1_n1_2h_sh-ZEB1_DMSO_7 | Breast cancer cells | shZeb1 | DMSO | 2 h |
SA353997 | 210514_MDA_ZEB1_n3_2h_sh-ZEB1_DMSO_25 | Breast cancer cells | shZeb1 | DMSO | 2 h |
SA354001 | 210514_MDA_ZEB1_n3_2h_sh-ZEB1_RSL3_10_uM_27 | Breast cancer cells | shZeb1 | RSL3 (10 µM) | 2 h |
SA354002 | 210514_MDA_ZEB1_n1_2h_sh-ZEB1_RSL3_10_uM_9 | Breast cancer cells | shZeb1 | RSL3 (10 µM) | 2 h |
SA354003 | 210514_MDA_ZEB1_n2_2h_sh-ZEB1_RSL3_10_uM_18 | Breast cancer cells | shZeb1 | RSL3 (10 µM) | 2 h |
SA353998 | 210514_MDA_ZEB1_n2_2h_sh-ZEB1_RSL3_1_uM_17 | Breast cancer cells | shZeb1 | RSL3 (1 µM) | 2 h |
SA353999 | 210514_MDA_ZEB1_n3_2h_sh-ZEB1_RSL3_1_uM_26 | Breast cancer cells | shZeb1 | RSL3 (1 µM) | 2 h |
SA354000 | 210514_MDA_ZEB1_n1_2h_sh-ZEB1_RSL3_1_uM_8 | Breast cancer cells | shZeb1 | RSL3 (1 µM) | 2 h |
SA353944 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n1_24h_DMSO_7 | Breast cancer cells | WT | DMSO | 24 h |
SA353945 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n5_24h_DMSO_77 | Breast cancer cells | WT | DMSO | 24 h |
SA353946 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n4_24h_DMSO_65 | Breast cancer cells | WT | DMSO | 24 h |
SA353947 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n3_24h_DMSO_46 | Breast cancer cells | WT | DMSO | 24 h |
SA353948 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n2_24h_DMSO_23 | Breast cancer cells | WT | DMSO | 24 h |
SA353935 | 210514_MDA_ZEB1_n3_2h_WT_DMSO_19 | Breast cancer cells | WT | DMSO | 2 h |
SA353936 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n2_2h_DMSO_17_correct | Breast cancer cells | WT | DMSO | 2 h |
SA353937 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n2_2h_RSL3_1uM_18 | Breast cancer cells | WT | DMSO | 2 h |
SA353938 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n5_2h_DMSO_73 | Breast cancer cells | WT | DMSO | 2 h |
SA353939 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n4_2h_DMSO_61 | Breast cancer cells | WT | DMSO | 2 h |
SA353940 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n3_2h_DMSO_37 | Breast cancer cells | WT | DMSO | 2 h |
SA353941 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n1_2h_DMSO_1 | Breast cancer cells | WT | DMSO | 2 h |
SA353942 | 210514_MDA_ZEB1_n1_2h_WT_DMSO_1 | Breast cancer cells | WT | DMSO | 2 h |
SA353943 | 210514_MDA_ZEB1_n2_2h_WT_DMSO_10 | Breast cancer cells | WT | DMSO | 2 h |
SA353949 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n2_4h_DMSO_19 | Breast cancer cells | WT | DMSO | 4 h |
SA353950 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n3_4h_DMSO_40 | Breast cancer cells | WT | DMSO | 4 h |
SA353951 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n1_4h_DMSO_3 | Breast cancer cells | WT | DMSO | 4 h |
SA353952 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n3_6h_DMSO_43 | Breast cancer cells | WT | DMSO | 6 h |
SA353953 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n2_6h_DMSO_21 | Breast cancer cells | WT | DMSO | 6 h |
SA353954 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n1_6h_DMSO_5 | Breast cancer cells | WT | DMSO | 6 h |
SA353977 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n3_24h_RSL3_10uM_48 | Breast cancer cells | WT | RSL3 (10 µM) | 24 h |
SA353978 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n4_24h_RSL3_10uM_66 | Breast cancer cells | WT | RSL3 (10 µM) | 24 h |
SA353979 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n5_24h_RSL3_10uM_78 | Breast cancer cells | WT | RSL3 (10 µM) | 24 h |
SA353971 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n4_2h_RSL3_10uM_62 | Breast cancer cells | WT | RSL3 (10 µM) | 2 h |
SA353972 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n3_2h_RSL3_10uM_39 | Breast cancer cells | WT | RSL3 (10 µM) | 2 h |
SA353973 | 210514_MDA_ZEB1_n2_2h_WT_RSL3_10_uM_12 | Breast cancer cells | WT | RSL3 (10 µM) | 2 h |
SA353974 | 210514_MDA_ZEB1_n3_2h_WT_RSL3_10_uM_21 | Breast cancer cells | WT | RSL3 (10 µM) | 2 h |
SA353975 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n5_2h_RSL3_10uM_74 | Breast cancer cells | WT | RSL3 (10 µM) | 2 h |
SA353976 | 210514_MDA_ZEB1_n1_2h_WT_RSL3_10_uM_3 | Breast cancer cells | WT | RSL3 (10 µM) | 2 h |
SA353980 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n5_4h_RSL3_10uM_75 | Breast cancer cells | WT | RSL3 (10 µM) | 4 h |
SA353981 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n3_4h_RSL3_10uM_42 | Breast cancer cells | WT | RSL3 (10 µM) | 4 h |
SA353982 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n4_4h_RSL3_10uM_63 | Breast cancer cells | WT | RSL3 (10 µM) | 4 h |
SA353983 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n5_6h_RSL3_10uM_76 | Breast cancer cells | WT | RSL3 (10 µM) | 6 h |
SA353984 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n3_6h_RSL3_10uM_45 | Breast cancer cells | WT | RSL3 (10 µM) | 6 h |
SA353985 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n4_6h_RSL3_10uM_64 | Breast cancer cells | WT | RSL3 (10 µM) | 6 h |
SA353962 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n2_24h_RSL3_1uM_24 | Breast cancer cells | WT | RSL3 (1 µM) | 24 h |
SA353963 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n3_24h_RSL3_1uM_47 | Breast cancer cells | WT | RSL3 (1 µM) | 24 h |
SA353964 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n1_24h_RSL3_1uM_8 | Breast cancer cells | WT | RSL3 (1 µM) | 24 h |
SA353955 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n1_2h_RSL3_1uM_2 | Breast cancer cells | WT | RSL3 (1 µM) | 2 h |
SA353956 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n2_2h_RSL3_1uM_18_correct | Breast cancer cells | WT | RSL3 (1 µM) | 2 h |
SA353957 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n2_2h_DMSO_17 | Breast cancer cells | WT | RSL3 (1 µM) | 2 h |
SA353958 | 210514_MDA_ZEB1_n2_2h_WT_RSL3_1_uM_11 | Breast cancer cells | WT | RSL3 (1 µM) | 2 h |
SA353959 | 210514_MDA_ZEB1_n1_2h_WT_RSL3_1_uM_2 | Breast cancer cells | WT | RSL3 (1 µM) | 2 h |
SA353960 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n3_2h_RSL3_1uM_38 | Breast cancer cells | WT | RSL3 (1 µM) | 2 h |
SA353961 | 210514_MDA_ZEB1_n3_2h_WT_RSL3_1_uM_20 | Breast cancer cells | WT | RSL3 (1 µM) | 2 h |
SA353965 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n1_4h_RSL3_1uM_4 | Breast cancer cells | WT | RSL3 (1 µM) | 4 h |
SA353966 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n3_4h_RSL3_1uM_41 | Breast cancer cells | WT | RSL3 (1 µM) | 4 h |
SA353967 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n2_4h_RSL3_1uM_20 | Breast cancer cells | WT | RSL3 (1 µM) | 4 h |
SA353968 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n3_6h_RSL3_1uM_44 | Breast cancer cells | WT | RSL3 (1 µM) | 6 h |
SA353969 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n1_6h_RSL3_1uM_6 | Breast cancer cells | WT | RSL3 (1 µM) | 6 h |
SA353970 | 210317_MDA_ZEB1_TC_pre_RSL3_WT_n2_6h_RSL3_1uM_22 | Breast cancer cells | WT | RSL3 (1 µM) | 6 h |
Showing results 1 to 69 of 69 |