Summary of Study ST000625

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000456. The data can be accessed directly via it's Project DOI: 10.21228/M83W49 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000625
Study TitleNon targeted metabolomic analysis of mouse and human bronchoalveolar lavage fluid, Aqueous(+) experiment (part I)
Study TypeComprehensive profile
Study SummaryMouse BALF was collected from C57BL/6 mice (n = 10). Five mice were exposed to ambient air for one day (air control) and five mice were exposed to CS for nine months (smoking). Human BALF was collected from subjects from the COPDGene cohort (n = 5). COPD diagnosis was based on the ratio of forced expiratory volume in 1 second to forced vital capacity (FEV1/FVC). Subjects were 45-70 years old, BMI 27-45, weight 76-125kg, and were categorized as follows: 1 male former smoker without COPD (FEV1/FVC = 0.82), 2 male current smokers without COPD (FEV1/FVC = 0.91 and 0.79), 1 female current smoker with moderate COPD (FEV1/FVC = 0.51), and 1 male current smoker with moderate COPD (FEV1/FVC = 0.64).
Institute
University of Colorado Denver
Department Anschutz Medical Campus, Pharmaceutical Sciences
LaboratoryMetabolomics and Mass Spectrometry
Last NameReisdorph
First NameNichole
Address12850 East Montview Blvd, Denver, CO 80204
Emailnichole.reisdorph@ucdenver.edu
Phone-
Submit Date2017-04-21
Num Groups2
Total Subjects15
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2018-12-11
Release Version1
Nichole Reisdorph Nichole Reisdorph
https://dx.doi.org/10.21228/M83W49
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Human | Animal; Subject species: Homo sapiens;Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Species SmokingStatus Phenotype
SA035132HBAL_11833GHuman Former smoker Moderate
SA035133HBAL_10031RHuman Smoker COPD
SA035134HBAL_17800VHuman Smoker COPD
SA035135HBAL_12558PHuman Smoker Healthy
SA035136HBAL_14442GHuman Smoker Healthy
SA035137MBAL_MET142Mouse Non-Smoker Healthy
SA035138MBAL_MET133Mouse Non-Smoker Healthy
SA035139MBAL_MET141Mouse Non-Smoker Healthy
SA035140MBAL_MET144Mouse Non-Smoker Healthy
SA035141MBAL_MET143Mouse Non-Smoker Healthy
SA035142MBAL_MET108Mouse Smoker Emphysema
SA035143MBAL_MET106Mouse Smoker Emphysema
SA035144MBAL_MET107Mouse Smoker Emphysema
SA035145MBAL_MET126Mouse Smoker Emphysema
SA035146MBAL_MET128Mouse Smoker Emphysema
Showing results 1 to 15 of 15
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