Summary of Study ST001804

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001136. The data can be accessed directly via it's Project DOI: 10.21228/M8VQ4D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001804
Study TitleHuman stool exposomics analysis
Study TypeUntargeted MS anlaysis
Study SummaryHuman stool samples, as a noninvasive matrix, have unique value in exposome research but have not been extensively studied for environmental chemical exposures. For lipophilic and unabsorbed dietary environmental chemicals, stool is a primary route of elimination and can therefore provide useful information on body burden and clearance of chemicals. In a pilot analysis of six human stool samples, we detected 52 and quantified 21 environmental chemicals, with HCB found in all samples. Quantification of HCB showed a median concentration of 0.057 ng/g. HCA of correlation matrix showed co-exposures of chemicals are likely as shown in the plasma, lung and thyroid. The high correlations of these persistent chemicals are not surprising as they likely derive from similar environmental exposure events.
Institute
Emory University
DepartmentMedicine/Pulmonary
LaboratoryDean Jones
Last NameHu
First NameXin
AddressEmory University Whitehead building (Rm 225), 615 Michael Street
Emailxin.hu2@emory.edu
Phone4047275091
Submit Date2021-05-07
Raw Data AvailableYes
Raw Data File Type(s)mzXML
Analysis Type DetailGC-MS
Release Date2021-05-28
Release Version1
Xin Hu Xin Hu
https://dx.doi.org/10.21228/M8VQ4D
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id type
SA167593Exstd5_1219_1external std
SA167594Exstd5_1219_2external std
SA167595Exstd5_1219external std
SA167596Exstd5_1019_2external std
SA167597Exstd5_1019external std
SA167598Exstd5_1019_1external std
SA167585NIST1957_2SRM1957
SA167586NIST1957_1SRM1957
SA167587NIST1957_3SRM1957
SA167588NIST1957_4SRM1957
SA167589NIST1958_4SRM1958
SA167590NIST1958_1SRM1958
SA167591NIST1958_3SRM1958
SA167592NIST1958_2SRM1958
SA167599BL_12172019_006stool
SA167600BL_12172019_007stool
SA167601BL_12172019_005stool
SA167602BL_12172019_003stool
SA167603BL_12172019_002stool
SA167604BL_12172019_008stool
SA167605BL_12172019_004stool
SA167606BL_12172019_009stool
SA167607BL_12172019_012stool
SA167608BL_12172019_001stool
SA167609BL_12172019_010stool
SA167610BL_12172019_011stool
SA167611Isooctane_3wash
SA167612Isooctane_1wash
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