Summary of Study ST001886

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001189. The data can be accessed directly via it's Project DOI: 10.21228/M8140K This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Show all samples  |  Perform analysis on untargeted data  
Download mwTab file (text)   |  Download mwTab file(JSON)   |  Download data files (Contains raw data)
Study IDST001886
Study TitleUntargeted metabolomics of hypertrophic cardiomyopathy (part I)
Study SummaryHypertrophic cardiomyopathy (HCM) is a complex disease partly explained by the effects of individual gene variants on sarcomeric protein biomechanics. At the cellular level, HCM mutations most commonly enhance force production, leading to higher energy demands. Despite significant advances in elucidating sarcomeric structure-function relationships, there is still much to be learned about the mechanisms that link altered cardiac energetics to HCM phenotypes. In this work, we test the hypothesis that changes in cardiac energetics represent a common pathophysiologic pathway in HCM.
Institute
Stanford University
Last NameContrepois
First NameKevin
Address300 Pasteur Dr
Emailkcontrep@stanford.edu
Phone6506664538
Submit Date2021-07-13
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2022-07-13
Release Version1
Kevin Contrepois Kevin Contrepois
https://dx.doi.org/10.21228/M8140K
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Group
SA175269D2540Donor
SA175270D2554Donor
SA175271D2507Donor
SA175272D2552Donor
SA175273D1331Donor
SA175274D1234Donor
SA175275M2799Hypertophic cardiomyopathy
SA175276M2800Hypertophic cardiomyopathy
SA175277M2803Hypertophic cardiomyopathy
SA175278M2860Hypertophic cardiomyopathy
SA175279M2692Hypertophic cardiomyopathy
SA175280M2939Hypertophic cardiomyopathy
SA175281M2856Hypertophic cardiomyopathy
SA175282M1455Hypertophic cardiomyopathy
SA175283M467Hypertophic cardiomyopathy
SA175284M433Hypertophic cardiomyopathy
SA175285M2673Hypertophic cardiomyopathy
SA175286M1385Hypertophic cardiomyopathy
SA175287M2622Hypertophic cardiomyopathy
SA175288A1067Hypertrophy control
SA175289A2971Hypertrophy control
SA175290MS270Mitral stenosis
Showing results 1 to 22 of 22
  logo