Summary of Study ST001176
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000788. The data can be accessed directly via it's Project DOI: 10.21228/M8TM3P This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST001176 |
Study Title | Metabolite changes in human plasma before and after YF17D vaccination in symptomatic and asymptomatic subjects |
Study Summary | Plasma was taken before and 1 day post-YF17D vaccination in a total of 13 subjects, of which 6 were asymptomatic and 7 were symptomatic. |
Institute | Duke-NUS Medical School |
Last Name | Chan |
First Name | Kuan Rong |
Address | 8 College Road Singapore 169857, Singapore, Singapore, 169857, Singapore |
kuanrong.chan@duke-nus.edu.sg | |
Phone | 90058277 |
Submit Date | 2019-04-25 |
Num Groups | 2 |
Total Subjects | 13 |
Raw Data Available | Yes |
Analysis Type Detail | CE-MS |
Release Date | 2019-05-15 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
Analysis ID | AN001952 |
---|---|
Analysis type | MS |
Chromatography type | CE |
Chromatography system | Agilent 6210 |
Column | Agilent capillary electrophoresis system |
MS Type | ESI |
MS instrument type | CE-TOFMS |
MS instrument name | Agilent 6210 TOF |
Ion Mode | UNSPECIFIED |
Units | uM |
MS:
MS ID: | MS001807 |
Analysis ID: | AN001952 |
Instrument Name: | Agilent 6210 TOF |
Instrument Type: | CE-TOFMS |
MS Type: | ESI |
MS Comments: | The spectrometer was scanned from m/z 50 to 1,000. Peaks were extracted using MasterHands, automatic integration software (Keio University, Tsuruoka, Yamagata, Japan) in order to obtain peak information including m/z, peak area, and migration time (MT)43. Signal peaks corresponding to isotopomers, adduct ions, and other product ions of known metabolites were excluded, and remaining peaks were annotated according to the HMT metabolite database based on their m/z values with the MTs. Areas of the annotated peaks were then normalized based on internal standard levels and sample volumes in order to obtain relative levels of each metabolite. Partial least square discriminant analysis was performed by HMT’s proprietary software, PeakStat and SampleStat, respectively. Pathway analysis is performed by MetaboAnalyst 4.0. |
Ion Mode: | UNSPECIFIED |