Summary of Study ST001209
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000805. The data can be accessed directly via it's Project DOI: 10.21228/M8MX2J This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST001209 |
Study Title | MARBLES (Markers of Autism Risk in Babies: Learning Early Sign) Enriched Cohort Study:Internal Metabolomic Biomarker Exposome and Development Disorders (IMBEDD) |
Study Summary | This project aims to identify internal biomarkers of drug, food and microbial exposures associated to Autism Spectrum Disorder (ASD) and neurodevelopmental outcomes in an enriched-risk cohort. Using targeted and untargeted internal exposome approaches to identify exposures in maternal blood and child cord blood, internal metabolomics biomarkers will be associated with related exposures and also associated with ASD. |
Institute | Emory University |
Department | School of Medicine |
Laboratory | Clincal Biomarkers Laboratory |
Last Name | Uppal |
First Name | Karan |
Address | NA |
kuppal2@emory.edu | |
Phone | (404) 727 5027 |
Submit Date | 2019-07-03 |
Total Subjects | 269 |
Study Comments | Both CHEAR pooled plasma samples and Clinical Biomarker Laboratory pooled plasma samples were used |
Raw Data Available | Yes |
Raw Data File Type(s) | raw(Thermo) |
Chear Study | 2016-1438 |
Analysis Type Detail | LC-MS |
Release Date | 2021-08-31 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
Analysis ID | AN002012 | AN002013 |
---|---|---|
Analysis type | MS | MS |
Chromatography type | HILIC | Reversed phase |
Chromatography system | Thermo Dionex Ultimate 3000 | Thermo Dionex Ultimate 3000 |
Column | Waters XBridge BEH Amide XP HILIC (50 x 2.1mm x 2.5um) with Thermo Accucore HILIC guard | Higgins endcapped C18 stainless steel (50 x 2.1mm,3um),Product #TS-0521-C183; Thermo Accucore C18 guard with holder,Product #17126-014005 |
MS Type | ESI | ESI |
MS instrument type | Orbitrap | Orbitrap |
MS instrument name | Thermo Q Exactive HF hybrid Orbitrap | Thermo Q Exactive HF hybrid Orbitrap |
Ion Mode | POSITIVE | NEGATIVE |
Units | peak area | peak area |
MS:
MS ID: | MS001865 |
Analysis ID: | AN002012 |
Instrument Name: | Thermo Q Exactive HF hybrid Orbitrap |
Instrument Type: | Orbitrap |
MS Type: | ESI |
MS Comments: | none |
Ion Mode: | POSITIVE |
Capillary Temperature: | 250C |
Collision Gas: | N2 |
Dry Gas Flow: | 45 |
Dry Gas Temp: | 150C |
Mass Accuracy: | < 3ppm |
Spray Voltage: | 3500 |
Activation Parameter: | 5.00E+05 |
Activation Time: | 118ms |
Interface Voltage: | S-Lens RF level= 55 |
Scanning Range: | 85-1275 |
Analysis Protocol File: | EmoryUniversity_HRM_QEHF-MS_092017_v1.pdf |
MS ID: | MS001866 |
Analysis ID: | AN002013 |
Instrument Name: | Thermo Q Exactive HF hybrid Orbitrap |
Instrument Type: | Orbitrap |
MS Type: | ESI |
MS Comments: | none |
Ion Mode: | NEGATIVE |
Capillary Temperature: | 250C |
Collision Gas: | N2 |
Dry Gas Flow: | 45 |
Dry Gas Temp: | 150C |
Mass Accuracy: | < 3ppm |
Spray Voltage: | -4000 |
Activation Parameter: | 5.00E+05 |
Activation Time: | 118ms |
Interface Voltage: | S-Lens RF level= 55 |
Scanning Range: | 85-1275 |
Analysis Protocol File: | EmoryUniversity_HRM_QEHF-MS_092017_v1.pdf |