Summary of Study ST001796
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001139. The data can be accessed directly via it's Project DOI: 10.21228/M8GH59 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST001796 |
Study Title | Changes in mesenteric lymph lipid profile of mice upon high-fat diet with and without Celecoxib |
Study Type | Untargeted lipidomics analysis |
Study Summary | Untargeted lipid profiling of mesenteric mice lymph from mice fed with CHOW, HFD and HFD supplemented with COx-2 inhibitor drug Celecoxib. It is proposed that Celecoxib can protect from deleterious morphological changes in lymphatic system caused by obesity due to HFD. |
Institute | Monash Institute of Pharmaceutical Sciences |
Department | Drug Delivery, Disposition and Dynamics |
Laboratory | Trevaskis Lab, Creek Lab |
Last Name | Anderson |
First Name | Dovile |
Address | 6 Anderson |
dovile.anderson@gmail.com | |
Phone | 8671141 |
Submit Date | 2021-05-17 |
Num Groups | 4 |
Total Subjects | 20 |
Num Males | 20 |
Publications | Manuscript NATMETAB-A20022406A Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential novel treatment target in obesity |
Raw Data Available | Yes |
Raw Data File Type(s) | raw(Thermo) |
Analysis Type Detail | LC-MS |
Release Date | 2021-06-02 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
Analysis ID | AN002917 | AN002918 |
---|---|---|
Analysis type | MS | MS |
Chromatography type | Reversed phase | Reversed phase |
Chromatography system | Thermo Dionex Ultimate 3000 RS | Thermo Dionex Ultimate 3000 RS |
Column | Sigma Aldrich,Supleco,C8 (100 x 2.1mm,2.7um) | Sigma Aldrich,Supleco,C8 (100 x 2.1mm,2.7um) |
MS Type | ESI | ESI |
MS instrument type | Orbitrap | Orbitrap |
MS instrument name | Thermo Q Exactive Orbitrap | Thermo Q Exactive Orbitrap |
Ion Mode | POSITIVE | NEGATIVE |
Units | height | height |
MS:
MS ID: | MS002709 |
Analysis ID: | AN002917 |
Instrument Name: | Thermo Q Exactive Orbitrap |
Instrument Type: | Orbitrap |
MS Type: | ESI |
MS Comments: | Pos and neg data were acquired during the same chromatographic run using polarity switching. Full scan acquisition mode, resolution 140k, AGC target 3e6, max IT 200 ms, mass range 140-2000 m/z, number of scans 1 |
Ion Mode: | POSITIVE |
Mass Accuracy: | 3 ppm |
Automatic Gain Control: | 3e6 |
Desolvation Gas Flow: | 34 |
Interface Voltage: | 3.5 kV |
MS ID: | MS002710 |
Analysis ID: | AN002918 |
Instrument Name: | Thermo Q Exactive Orbitrap |
Instrument Type: | Orbitrap |
MS Type: | ESI |
MS Comments: | Pos and neg data were acquired during the same chromatographic run using polarity switching. Full scan acquisition mode, resolution 140k, AGC target 3e6, max IT 200 ms, mass range 140-2000 m/z, number of scans 1 |
Ion Mode: | NEGATIVE |
Mass Accuracy: | 3 ppm |
Automatic Gain Control: | 3e6 |
Desolvation Gas Flow: | 34 |
Interface Voltage: | 3.5 kV |