Summary of Study ST002339
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001502. The data can be accessed directly via it's Project DOI: 10.21228/M8JD81 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002339 |
Study Title | Myriocin rescue of serine-associated hepatic lipid diversity |
Study Summary | We analyzed hepatic polar and lipid metabolites in mice (C57BL/6J) in response to two dietary interventions. The first was: 1) low fat (LFD), 2) serine/glycine-free LFD (-SG LFD), high fat (HFD), and serine/glycine-free HFD (-SG HFD). And the second was: 1) low fat (LFD), high fat (HFD), serine/glycine-free HFD (-SG HFD), and serine/glycine-free HFD (-SG HFD) with myriocin (0.3 mg/kg every other day) treatment. The goal of the study was to determine the impact of dietary serine/glycine restriction and myriocin treatment on the hepatic lipidome. |
Institute | Salk Institute for Biological Studies |
Department | Molecular and Cell Biology Laboratory |
Laboratory | Metallo Lab |
Last Name | Handzlik |
First Name | Michal |
Address | 10010 N Torrey Pines Rd, La Jolla, California, 92037, USA |
mhandzlik@salk.edu | |
Phone | 2069601945 |
Submit Date | 2022-11-10 |
Num Groups | LFD, -SG LFD, HFD, -SG HFD, LFD+Veh, HFD+Veh, -SG HFD+Veh, -SG HFD+Myr |
Total Subjects | 88 |
Num Males | 88 |
Raw Data Available | Yes |
Raw Data File Type(s) | mzXML |
Analysis Type Detail | LC-MS |
Release Date | 2024-01-01 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
Analysis ID | AN003822 |
---|---|
Analysis type | MS |
Chromatography type | Reversed phase |
Chromatography system | Thermo Vanquish |
Column | Thermo Accucore C30 (150 x 2.1mm,2.6um) |
MS Type | ESI |
MS instrument type | Ion trap |
MS instrument name | Thermo Q Exactive Orbitrap |
Ion Mode | POSITIVE |
Units | normalized ion count/mg protein |
MS:
MS ID: | MS003564 |
Analysis ID: | AN003822 |
Instrument Name: | Thermo Q Exactive Orbitrap |
Instrument Type: | Ion trap |
MS Type: | ESI |
MS Comments: | El-MAVEN |
Ion Mode: | POSITIVE |