Summary of Study ST002996
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001866. The data can be accessed directly via it's Project DOI: 10.21228/M8HM8S This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002996 |
| Study Title | Tissue Lipidomic Profiling for Detection of Non-Small Cell Lung Cancer |
| Study Summary | UPLC-HRMS analysis was performed on AC and SCC patients. OPLSDA classfication was performed on tumor vs. ANT and DNT samples. Panels of discriminant features were identified. The biomarkers identified in discovery set samples for each binary classification were confirmed by using a set of validation samples, which were run separately. Additionally, paired analysis showed the abundance of discriminant compounds has significant altered in tumor tissues compared to corresponding DNT and ANT samples, reflecting the lipid characteristics related to tumor in situ and cancer cell signaling. |
| Institute | OUC |
| Department | Department of Medicine and Pharmacy |
| Laboratory | Analytical chemistry |
| Last Name | Zhang |
| First Name | Jie |
| Address | No. 5 Yushan Road, Qingdao, Shandong, China |
| zhangjieqau@163.com | |
| Phone | 17806277823 |
| Submit Date | 2023-11-16 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2023-12-27 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN004921 |
|---|---|
| Analysis type | MS |
| Chromatography type | Reversed phase |
| Chromatography system | Agilent 1290 Infinity |
| Column | Waters ACQUITY UPLC BEH C18 (50 x 2.1mm,1.7um) |
| MS Type | ESI |
| MS instrument type | Orbitrap |
| MS instrument name | Thermo LTQ XL |
| Ion Mode | POSITIVE |
| Units | Peak area |
MS:
| MS ID: | MS004664 |
| Analysis ID: | AN004921 |
| Instrument Name: | Thermo LTQ XL |
| Instrument Type: | Orbitrap |
| MS Type: | ESI |
| MS Comments: | capillary temperature 300 °C, capillary voltage 20 V, tube lens 35 V, spray voltage 4.0 kV for positive ion mode, auxiliary gas, sheath gas and sweep gas flow rate 10, 40, and 0 arbitrary units. Progenesis QI version 2.4 was used for raw data processing. FORTRAN based home-built secondary data processing was applied for artefact removal, blank correction, QC -based signal correction and normalization, etc. |
| Ion Mode: | POSITIVE |
