Summary of Study ST001280
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000865. The data can be accessed directly via it's Project DOI: 10.21228/M8W40B This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST001280 |
Study Title | Macrophage-Mediated Clofazimine Sequestration is Accompanied by a Shift in Host Energy Metabolism |
Study Type | 4 timepoints for urine collection, whole blood collected at sacrifice (8 weeks) |
Study Summary | Examined the effects of long-term dosing with CFZ of mice, metabolic data on CFZ and sham mice was collected at 0, 2, 4, and 8 weeks, at 8 weeks mice were sacrificed and WB was collected from 6 CFZ treated mice and 7 sham mice |
Institute | University of Michigan |
Department | Clinical Pharmacy |
Laboratory | NMR Metabolomics Laboratory, University of Michigan |
Last Name | Stringer |
First Name | Kathleen |
Address | College of Pharmacy, 428 Church St, Ann Arbor, MI, 48109 |
NMRmetabolomics@umich.edu | |
Phone | 734-647-4775 |
Submit Date | 2019-11-05 |
Num Groups | 2 |
Total Subjects | 13, 48 urine Samples, 13 WB Samples |
Num Males | 13 |
Publications | 10.1016/j.xphs.2016.12.009 |
Raw Data File Type(s) | fid |
Analysis Type Detail | NMR |
Release Date | 2020-01-13 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
NMR:
NMR ID: | NM000153 |
Analysis ID: | AN002121 |
Instrument Name: | Varian 500 MHz |
Instrument Type: | FT-NMR |
NMR Experiment Type: | 1D-1H |
NMR Comments: | Arrayed for water saturation frequency and 90deg. pulse width for each sample |
Spectrometer Frequency: | 500 MHz |
NMR Probe: | ONE-Probe |
NMR Solvent: | D2O |
NMR Tube Size: | 5mm |
Shimming Method: | Auto shim (gradient shimming), manual when necessary. |
Pulse Sequence: | 1D-NOESY |
Water Suppression: | saturation at 80 Hz induced field strength |
Pulse Width: | 5.5ms |
Offset Frequency: | around -178Hz |
Chemical Shift Ref Cpd: | DSS-d6 IS-2 (Chenomx) |
Temperature: | 25 |
Number Of Scans: | 32 |