Summary of Study ST001913
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000319. The data can be accessed directly via it's Project DOI: 10.21228/M8H029 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST001913 |
Study Title | Stool metabolomics in the New Hampshire Birth Cohort Study |
Study Type | Untargeted and semi-targeted metabolomics analysis |
Study Summary | This is a study of data collected from fecal samples from larger New Hampshire Birth Cohort Study (NHBCS). 1H NMR metabolomic profiling of 524 infant stool samples collected at 6 week - 3 year age was performed and spectra were binned (untargeted metabolomics). A set of host-microbiome co-metabolites were library matched in individual sample spectra and their relative concentrations were determined. This study investigated associations of the functional metabolic response of the microbial milieu of the infant gut with environmental and other factors. |
Institute | University of North Carolina at Chapel Hill |
Department | Nutrition |
Laboratory | Metabolomics and Exposome Laboratory, Nutrition Research Institute, UNC Chapel Hill |
Last Name | Sumner |
First Name | Susan |
Address | 500 Laureate Way, Kannapolis, NC 28081 |
susan_sumner@unc.edu | |
Phone | (919) 622-4456 |
Submit Date | 2021-08-09 |
Num Groups | 2 |
Total Subjects | 524 |
Study Comments | The number of groups includes the QC samples, Total samples = 572 |
Raw Data Available | Yes |
Analysis Type Detail | NMR |
Release Date | 2023-01-31 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
NMR:
NMR ID: | NM000214 |
Analysis ID: | AN003111 |
Instrument Name: | Avance III 700 MHz NMR Spectrometer |
Instrument Type: | FT-NMR |
NMR Experiment Type: | 1D-1H |
Field Frequency Lock: | 3015 Hz, D2O |
Standard Concentration: | 0.5 mM |
Spectrometer Frequency: | 700 MHz |
NMR Probe: | CP QCI/HPCN |
NMR Solvent: | 90% H2O, 10% D2O |
NMR Tube Size: | 5 mm |
Shimming Method: | topshim |
Pulse Sequence: | noesygppr1d |
Water Suppression: | pre-saturation |
Pulse Width: | 14.59 us |
Power Level: | 12.3 Watts |
Receiver Gain: | 36 |
Offset Frequency: | 3290.61 Hz |
Presaturation Power Level: | 0.0000964 Watts |
Chemical Shift Ref Cpd: | DSS-d6 |
Temperature: | 25 C |
Number Of Scans: | 64 |
Dummy Scans: | 4 |
Acquisition Time: | 3.9 seconds |
Relaxation Delay: | 2 seconds |
Spectral Width: | 12 ppm |
Num Data Points Acquired: | 65536 |
Real Data Points: | 32768 |
Line Broadening: | 0.5 Hz |
Zero Filling: | Yes |
Apodization: | Lorentzian |
Baseline Correction Method: | Polynomial |
Chemical Shift Ref Std: | DSS-d6 |
Binned Increment: | 0.04ppm |
Binned Data Excluded Range: | 4.79 - 4.85 ppm (Water region) |