Summary of Study ST000603
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000440. The data can be accessed directly via it's Project DOI: 10.21228/M85W25 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST000603 |
Study Title | Urinary Volatile Compound, Associated with Chronic Inflammation In Interstitial Cystitis |
Study Summary | Interstitial cystitis (IC)/bladder pain syndrome (BPS) is a clinical condition that manifests as a sensory hypersensitivity of unknown cause and is characterized by urinary frequency, bladder discomfort, and pelvic pain. In the present volatolomic study, we have analyzed the VOCs unique to urine specimens obtained from interstitial cystitis patients, in compassion to healthy controls.This is the novel finding from comprehensive and unbiased metabolomics analysis that urinary menthol is decreased in urine specimens from IC patients, and that the reduced menthol level in IC is potentially linked to the chronic inflammation, which is often observed in IC patients |
Institute | University of California, Davis |
Department | Genome and Biomedical Sciences Facility |
Laboratory | WCMC Metabolomics Core |
Last Name | Fiehn |
First Name | Oliver |
Address | Health Sciences Drive, Davis, California, 95616, USA |
ofiehn@ucdavis.edu | |
Phone | (530) 754-8258 |
Submit Date | 2017-05-09 |
Raw Data Available | Yes |
Raw Data File Type(s) | cdf |
Analysis Type Detail | GC-MS |
Release Date | 2017-07-10 |
Release Version | 1 |
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Project:
Project ID: | PR000440 |
Project DOI: | doi: 10.21228/M85W25 |
Project Title: | Urinary Volatile Compound, Associated with Chronic Inflammation In Interstitial Cystitis |
Project Summary: | Interstitial cystitis (IC)/bladder pain syndrome (BPS) is a clinical condition that manifests as a sensory hypersensitivity of unknown cause and is characterized by urinary frequency, bladder discomfort, and pelvic pain. In the present volatolomic study, we have analyzed the VOCs unique to urine specimens obtained from interstitial cystitis patients, in compassion to healthy controls.This is the novel finding from comprehensive and unbiased metabolomics analysis that urinary menthol is decreased in urine specimens from IC patients, and that the reduced menthol level in IC is potentially linked to the chronic inflammation, which is often observed in IC patients |
Institute: | Cedars-Sinai Medical Center |
Last Name: | Kim |
First Name: | Jayoung |
Address: | 8700 Beverly Blvd. Davis Research Building Ste 5071 Los Angeles, CA 90048 |
Email: | jayoung.kim@cshs.org |
Phone: | 310-423-7168 |