Summary of Study ST002022
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001284. The data can be accessed directly via it's Project DOI: 10.21228/M8R71H This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002022 |
Study Title | A Sentinel Serum Quality Management Program for NMR Metabolomics |
Study Type | Pharmacometabolomics |
Study Summary | Pooled human serum (Sentinel Serum Samples) was aliquoted for storage at -80C and subsequently had NMR spectra acquired annually for three years. This was to determine sentinel serum sample utility for a quality management program to monitor NMR reproducibility. Sentinel serum quality control samples allowed the quantification of variance between different profilers within a project. They also demonstrated declines in metabolite concentrations over time. A sentinel program is useful for tracking changes in QC serum samples from long-term storage. Separately, QC samples show negligible variance introduced by multiple profilers of NMR spectra within a project. |
Institute | University of Michigan |
Department | Clinical Pharmacy |
Laboratory | UMich NMR Metabolomics Laboratory |
Last Name | Stringer |
First Name | Kathleen |
Address | 428 Church Street |
stringek@med.umich.edu; stringek@umich.edu | |
Phone | 7346474775 |
Submit Date | 2021-11-30 |
Num Groups | 3 |
Total Subjects | 1 |
Study Comments | Samples were aliquots of a batch of pooled human serum, collected from multiple different individuals |
Raw Data Available | Yes |
Raw Data File Type(s) | d |
Analysis Type Detail | NMR |
Release Date | 2022-01-06 |
Release Version | 1 |
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Project:
Project ID: | PR001284 |
Project DOI: | doi: 10.21228/M8R71H |
Project Title: | A Sentinel Serum Quality Management Program for NMR Metabolomics |
Project Type: | Metabolomics |
Project Summary: | Pooled human serum (Sentinel Serum Samples) was aliquoted for storage at -80C and subsequently had NMR spectra acquired annually for three years. This was to determine sentinel serum sample utility for a quality management program to monitor NMR reproducibility. Sentinel serum quality control samples allowed the quantification of variance between different profilers within a project. They also demonstrated declines in metabolite concentrations over time. A sentinel program is useful for tracking changes in QC serum samples from long-term storage. Separately, QC samples show negligible variance introduced by multiple profilers of NMR spectra within a project. |
Institute: | University of Michigan |
Department: | Clinical Pharmacy |
Laboratory: | UMich NMR Metabolomics Laboratory |
Last Name: | Stringer |
First Name: | Kathleen |
Address: | 428 Church Street |
Email: | stringek@med.umich.edu; stringek@umich.edu |
Phone: | 7346474775 |
Funding Source: | NIH/NIGMS |
Contributors: | T. Flott, K Stringer |